TR200402322T4 - Triptaz inhibitörler - Google Patents

Triptaz inhibitörler

Info

Publication number
TR200402322T4
TR200402322T4 TR2004/02322T TR200402322T TR200402322T4 TR 200402322 T4 TR200402322 T4 TR 200402322T4 TR 2004/02322 T TR2004/02322 T TR 2004/02322T TR 200402322 T TR200402322 T TR 200402322T TR 200402322 T4 TR200402322 T4 TR 200402322T4
Authority
TR
Turkey
Prior art keywords
tryptase inhibitors
inhibitors
tryptase
compounds
formula
Prior art date
Application number
TR2004/02322T
Other languages
English (en)
Inventor
Bar Thomas
Stadlwieser Josef
Ulrich Wolf-R�diger
Dominik Andreas
Bundschuh Daniela
Zech Karl
Sommerhoff Christian
Martin Thomas
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of TR200402322T4 publication Critical patent/TR200402322T4/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Mevcut bulus, ilaçlarin hazirlanmasi için farmasötik endüstirisinde kullanilan yeni triptaz inhibitörler ile ilgilidir. Bulus özellikle, asagidaki formül I'e ait bilesikleri ve bu bilesiklerin tuzlarini ve azot içeren heterosikloalkilen'lerin N-oksitlerini ve bunlarin tuzlarini temin etmektedir.
TR2004/02322T 1999-12-20 2000-12-16 Triptaz inhibitörler TR200402322T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99125384 1999-12-20

Publications (1)

Publication Number Publication Date
TR200402322T4 true TR200402322T4 (tr) 2004-12-21

Family

ID=8239661

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2004/02322T TR200402322T4 (tr) 1999-12-20 2000-12-16 Triptaz inhibitörler

Country Status (13)

Country Link
US (1) US7015325B2 (tr)
EP (1) EP1244643B1 (tr)
JP (1) JP2003518109A (tr)
AT (1) ATE269313T1 (tr)
AU (1) AU783217B2 (tr)
CA (1) CA2392121A1 (tr)
DE (1) DE60011677T2 (tr)
DK (1) DK1244643T3 (tr)
ES (1) ES2222259T3 (tr)
PT (1) PT1244643E (tr)
SI (1) SI1244643T1 (tr)
TR (1) TR200402322T4 (tr)
WO (1) WO2001046168A1 (tr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1358182E (pt) 2001-01-31 2004-12-31 Altana Pharma Ag Derivados de diazocinas e sua utilizacao como inibidores de triptase
DE60220504T2 (de) 2001-02-21 2008-02-14 Nycomed Gmbh Tryptasehemmer
AU2002253035B8 (en) 2001-02-21 2008-02-21 Altana Pharma Ag Tryptase inhibitors
US20040087792A1 (en) * 2001-03-15 2004-05-06 Thomas Martin Tryptase-inhibitors
WO2002074732A2 (en) * 2001-03-15 2002-09-26 Altana Pharma Ag Tryptase-inhibitors
DE60216920T2 (de) 2001-06-19 2007-11-15 Nycomed Gmbh Tryptase-inhibitoren
GB0507577D0 (en) * 2005-04-14 2005-05-18 Novartis Ag Organic compounds
JP7383483B2 (ja) * 2017-03-29 2023-11-20 ミネルバ バイオテクノロジーズ コーポレーション 幹細胞を分化し、癌を処置するための作用薬

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3999946A (en) * 1976-02-23 1976-12-28 Allied Chemical Corporation Time-temperature history indicators
US4228126A (en) * 1977-11-25 1980-10-14 Allied Chemical Corporation Diacetylene time-temperature indicators
WO1995032945A1 (en) * 1994-06-01 1995-12-07 Arris Pharmaceutical Corporation Compositions and methods for treating mast-cell mediated conditions
HUT77770A (hu) * 1994-09-23 1998-08-28 Axys Pharmaceuticals, Inc. Készítmény és eljárás hízósejtek által közvetített gyulladásos állapotok kezelésére
NZ333713A (en) * 1996-07-30 2000-12-22 Axys Pharm Inc Compounds for treating diseases associated with tryptase activity
US6221914B1 (en) * 1997-11-10 2001-04-24 Array Biopharma Inc. Sulfonamide bridging compounds that inhibit tryptase activity
PT1060175E (pt) 1998-02-06 2005-03-31 Max Planck Ges Ford Wissenscha Inibidores de triptase
AU2723099A (en) 1998-02-06 1999-08-23 Byk Gulden Lomberg Chemische Fabrik Gmbh Tryptase inhibitors
IL141654A0 (en) 1998-09-04 2002-03-10 Byk Gulden Lomberg Chem Fab Pyranose derivatives and pharmaceutical compositions containing the same
KR20020016942A (ko) 1999-08-10 2002-03-06 빅 굴덴 롬베르크 케미쉐 파브릭 게엠베하 디아조신-디온 유도체 및 이것의 트립타제 억제제로서 용도
EP1216236A1 (en) 1999-09-14 2002-06-26 Byk Gulden Lomberg Chemische Fabrik GmbH Tryptase inhibitors

Also Published As

Publication number Publication date
AU783217B2 (en) 2005-10-06
JP2003518109A (ja) 2003-06-03
US20030083344A1 (en) 2003-05-01
ES2222259T3 (es) 2005-02-01
ATE269313T1 (de) 2004-07-15
DE60011677T2 (de) 2005-07-14
SI1244643T1 (en) 2004-12-31
PT1244643E (pt) 2004-10-29
EP1244643B1 (en) 2004-06-16
US7015325B2 (en) 2006-03-21
WO2001046168A1 (en) 2001-06-28
CA2392121A1 (en) 2001-06-28
AU2166901A (en) 2001-07-03
DK1244643T3 (da) 2004-10-18
EP1244643A1 (en) 2002-10-02
DE60011677D1 (en) 2004-07-22

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