NO990433L - Nye forbindelser og blandinger for behandling av sykdommer i forbindelse med tryptase-aktivitet - Google Patents

Nye forbindelser og blandinger for behandling av sykdommer i forbindelse med tryptase-aktivitet

Info

Publication number
NO990433L
NO990433L NO990433A NO990433A NO990433L NO 990433 L NO990433 L NO 990433L NO 990433 A NO990433 A NO 990433A NO 990433 A NO990433 A NO 990433A NO 990433 L NO990433 L NO 990433L
Authority
NO
Norway
Prior art keywords
compositions
treatment
diseases associated
new compounds
tryptase activity
Prior art date
Application number
NO990433A
Other languages
English (en)
Norwegian (no)
Other versions
NO990433D0 (no
Inventor
Jeffrey Mark Dener
Elaine Yee-Lin Kuo
Ken Duane Rice
Vivian Rueywen Wang
Wendy Beth Young
Original Assignee
Arris Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arris Pharm Corp filed Critical Arris Pharm Corp
Publication of NO990433D0 publication Critical patent/NO990433D0/no
Publication of NO990433L publication Critical patent/NO990433L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C07D233/08Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
    • C07D233/12Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D233/14Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
NO990433A 1996-07-30 1999-01-29 Nye forbindelser og blandinger for behandling av sykdommer i forbindelse med tryptase-aktivitet NO990433L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2313996P 1996-07-30 1996-07-30
US89577297A 1997-07-17 1997-07-17
PCT/US1997/013422 WO1998004537A1 (en) 1996-07-30 1997-07-30 Novel compounds and compositions for treating diseases associated with tryptase activity

Publications (2)

Publication Number Publication Date
NO990433D0 NO990433D0 (no) 1999-01-29
NO990433L true NO990433L (no) 1999-03-25

Family

ID=26696778

Family Applications (1)

Application Number Title Priority Date Filing Date
NO990433A NO990433L (no) 1996-07-30 1999-01-29 Nye forbindelser og blandinger for behandling av sykdommer i forbindelse med tryptase-aktivitet

Country Status (17)

Country Link
EP (1) EP0934293A1 (sv)
JP (1) JP2001509787A (sv)
KR (1) KR20000029679A (sv)
CN (1) CN1073103C (sv)
AU (1) AU733621B2 (sv)
CA (1) CA2262542A1 (sv)
CZ (1) CZ29799A3 (sv)
EE (1) EE9900036A (sv)
FI (1) FI990171A (sv)
HU (1) HUP0003267A3 (sv)
LV (1) LV12291B (sv)
NO (1) NO990433L (sv)
NZ (1) NZ333713A (sv)
PL (1) PL331465A1 (sv)
SI (1) SI9720047A (sv)
SK (1) SK8599A3 (sv)
WO (1) WO1998004537A1 (sv)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221914B1 (en) 1997-11-10 2001-04-24 Array Biopharma Inc. Sulfonamide bridging compounds that inhibit tryptase activity
EP1060171A2 (de) * 1998-02-06 2000-12-20 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Tryptase-inhibitoren
ES2233025T3 (es) * 1998-02-06 2005-06-01 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Agente inhibidores de la triptasa.
AU5625499A (en) * 1998-09-04 2000-03-27 Altana Pharma Ag Novel pyranoses
DE60014932T2 (de) 1999-08-10 2005-10-13 Altana Pharma Ag Diazocindionderivate und ihre verwendung als tryptase inhibitoren
AU778965B2 (en) * 1999-09-14 2004-12-23 Altana Pharma Ag Tryptase inhibitors
WO2001036386A1 (fr) * 1999-11-17 2001-05-25 Sumitomo Pharmaceuticals Co., Ltd. Traitement du diabete contenant un derive de dipiperazine
DE19955476A1 (de) * 1999-11-18 2001-05-23 Boehringer Ingelheim Pharma Bis-basische Verbindungen als Tryptase-Inhibitoren, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
CA2392127A1 (en) 1999-12-20 2001-06-28 Byk Gulden Lomberg Chemische Fabrik Gmbh Tryptase inhibitors
TR200402322T4 (tr) * 1999-12-20 2004-12-21 Altana Pharma Ag Triptaz inhibitörler
DK1358182T3 (da) * 2001-01-31 2004-12-20 Altana Pharma Ag Diazocin-derivater og anvendelsen deraf som tryptase-inhibitorer
ATE349427T1 (de) 2001-02-21 2007-01-15 Altana Pharma Ag Tryptaseinhibitoren
CA2438711A1 (en) 2001-02-21 2002-08-29 Altana Pharma Ag Tryptase inhibitors
US20040087792A1 (en) * 2001-03-15 2004-05-06 Thomas Martin Tryptase-inhibitors
WO2002074732A2 (en) * 2001-03-15 2002-09-26 Altana Pharma Ag Tryptase-inhibitors
AU2002345664C1 (en) 2001-06-11 2008-03-06 Xenoport, Inc. Prodrugs of gaba analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
ES2278928T3 (es) 2001-06-19 2007-08-16 Altana Pharma Ag Inhibidores de triptasa.
WO2006050514A1 (en) 2004-11-04 2006-05-11 Xenoport, Inc. Gabapentin prodrug sustained release oral dosage forms
TWI432188B (zh) 2008-12-19 2014-04-01 Merz Pharma Gmbh & Co Kgaa 供治療發炎性皮膚疾病之1-胺基-烷基環己烷衍生物類
AU2009328497A1 (en) 2008-12-19 2010-06-24 Merz Pharma Gmbh & Co. Kgaa 1-amino-alkylcyclohexane derivatives for the treatment of mast cell mediated diseases
FR3038605B1 (fr) 2015-07-06 2018-08-24 Universite Amiens Picardie Jules Verne Diamines primaires vicinales associees a des motifs chelateurs de metaux et/ou de radicaux libres, actives contre les stress carbonyle et oxydant et leur utilisation
CN110869362A (zh) * 2017-05-12 2020-03-06 国立研究开发法人理化学研究所 A类gpcr结合性化合物改性体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4845242A (en) * 1987-04-28 1989-07-04 Georgia Tech Research Corporation Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
JPH08507768A (ja) * 1993-03-12 1996-08-20 アリス ファーマシューティカル コーポレイション 免疫仲介炎症疾患の処置のための組成物および方法
US5525623A (en) * 1993-03-12 1996-06-11 Arris Pharmaceutical Corporation Compositions and methods for the treatment of immunomediated inflammatory disorders
JPH10501238A (ja) * 1994-06-01 1998-02-03 アリス ファーマシューティカル コーポレイション 肥満細胞媒介症状を治療するための組成物及び方法
SI9520101A (en) * 1994-09-23 1997-12-31 Arris Pharm Corp Compositions and methods for treating mast-cell inflammatory condition
KR19980703261A (ko) * 1995-03-24 1998-10-15 다니엘 이이치. 페트리 가역성 프로테아제 억제제
TW438591B (en) * 1995-06-07 2001-06-07 Arris Pharm Corp Reversible cysteine protease inhibitors

Also Published As

Publication number Publication date
AU733621B2 (en) 2001-05-17
JP2001509787A (ja) 2001-07-24
FI990171A (sv) 1999-03-23
SI9720047A (sl) 1999-08-31
FI990171A0 (sv) 1999-01-29
HUP0003267A3 (en) 2002-02-28
NO990433D0 (no) 1999-01-29
CN1226892A (zh) 1999-08-25
AU3967097A (en) 1998-02-20
CN1073103C (zh) 2001-10-17
SK8599A3 (en) 2000-03-13
LV12291A (lv) 1999-06-20
CA2262542A1 (en) 1998-02-05
NZ333713A (en) 2000-12-22
PL331465A1 (en) 1999-07-19
KR20000029679A (ko) 2000-05-25
EP0934293A1 (en) 1999-08-11
EE9900036A (et) 1999-08-16
CZ29799A3 (cs) 1999-06-16
HUP0003267A2 (hu) 2001-06-28
LV12291B (en) 2000-04-20
WO1998004537A1 (en) 1998-02-05

Similar Documents

Publication Publication Date Title
NO990433L (no) Nye forbindelser og blandinger for behandling av sykdommer i forbindelse med tryptase-aktivitet
AU2003301020A1 (en) Isoquinolinone derivatives and their use as therapeutic agents
NO20021328L (no) Pyrazolopyrimidier som terapeutiske midler
NO20012977D0 (no) N-ureidoalkylpiperidiner som modulatorer av chemokinreseptoraktivitet
NO20093464L (no) Nye medikamentblandinger basert pa anti-cholinergisk effektive forbindelser og beta-mimetika
SE0202462D0 (sv) Novel use
DK1178958T3 (da) N-cyanomethylamider som proteaseinhibitorer
MXPA02012712A (es) N-ureidoheterocicloalquil-piperidinas como moduladores de la actividad del receptor de quimiocinas.
NO992400L (no) Nye substituerte pyrazolderivater
NO20051263L (no) Ny anvendelse av benzotiazolderivater
ATE302606T1 (de) N-ureidoalkylpiperidine als modulatoren der aktivität der chemokinrezeptoren
NO963731L (no) Behandling av obsessive-kompulsive sykdommer med 5HT2-antagonister
BR0109211A (pt) Compostos com atividade 5-ht1a úteis para o tratamento de distúrbios da retina externa
NO20014529D0 (no) Tetrahydropyranderivater og deres anvendelse som terapautiske midler
NO20073113L (no) Indenylderivater og anvendelse derav for behandling av neurologiske lidelser
DK0888271T3 (da) Benzamidinderivater substitueret med aminosyre- og hydroxysyrederivater og deres anvendelse som antikoagulerende midler
NO20016201L (no) Tienopyrimidiner som fosfodiesteraseinhibitorer
DE60031686D1 (de) Pyrazinone, diese verbindungen enthaltende zusammenstellungen
NO982863L (no) Nye forbindelser med analgetisk effekt
DK0871446T3 (da) Anvendelse af eliprodil til fremstilling af et lægemiddel til behandling af ischaemiske sygdomme i nethinden eller den optiske nerve
BR0317289A (pt) Método para tratar distúrbios do movimento usando derivados do ácido barbitúrico
WO2000076500A3 (en) Compound for use as a medicament for treatment of disorders involving bronchocontraction
DK0767783T3 (da) Substituerede alkyldiaminderivater og deres anvendelse som tachykinin-antagonister
BRPI0415546A (pt) composto, composição farmacêutica, uso de um composto, e, métodos de tratamento ou profilaxia de doenças ou condições humanas, e de distúrbios
NO20001846L (no) Nye farmasøytisk aktive forbindelser, deres fremstilling og anvendelse som ECE-inhibitorer

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application