SI2959894T1 - S1P receptorski modulatorji za zdravljenje multiple skleroze - Google Patents
S1P receptorski modulatorji za zdravljenje multiple sklerozeInfo
- Publication number
- SI2959894T1 SI2959894T1 SI200732191T SI200732191T SI2959894T1 SI 2959894 T1 SI2959894 T1 SI 2959894T1 SI 200732191 T SI200732191 T SI 200732191T SI 200732191 T SI200732191 T SI 200732191T SI 2959894 T1 SI2959894 T1 SI 2959894T1
- Authority
- SI
- Slovenia
- Prior art keywords
- multiple sclerosis
- receptor modulators
- treating multiple
- treating
- modulators
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0612721.1A GB0612721D0 (en) | 2006-06-27 | 2006-06-27 | Organic compounds |
EP15177166.4A EP2959894B1 (en) | 2006-06-27 | 2007-06-25 | S1p receptor modulators for treating multiple sclerosis |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2959894T1 true SI2959894T1 (sl) | 2022-11-30 |
Family
ID=36888144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200732191T SI2959894T1 (sl) | 2006-06-27 | 2007-06-25 | S1P receptorski modulatorji za zdravljenje multiple skleroze |
Country Status (21)
Country | Link |
---|---|
US (3) | US20100168078A1 (sl) |
EP (4) | EP2959894B1 (sl) |
JP (7) | JP2009541386A (sl) |
KR (6) | KR20210010956A (sl) |
CN (2) | CN103550195A (sl) |
AU (7) | AU2007264031C1 (sl) |
BR (1) | BRPI0713985A2 (sl) |
CA (1) | CA2653569C (sl) |
DE (1) | DE15177166T1 (sl) |
DK (1) | DK2959894T3 (sl) |
ES (1) | ES2887042T3 (sl) |
GB (1) | GB0612721D0 (sl) |
HK (1) | HK1214758A1 (sl) |
HU (1) | HUE059922T4 (sl) |
LT (1) | LT2959894T (sl) |
MX (3) | MX2008016133A (sl) |
PL (1) | PL2959894T3 (sl) |
PT (1) | PT2959894T (sl) |
RU (1) | RU2617502C2 (sl) |
SI (1) | SI2959894T1 (sl) |
WO (1) | WO2008000419A1 (sl) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
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GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
CA2684953C (en) * | 2007-05-04 | 2016-08-09 | Novartis Ag | Use of s1p receptor modulator |
EP3545953A1 (en) * | 2008-06-20 | 2019-10-02 | Novartis AG | Paediatric compositions for treating1 multiple sclerosis |
CA2733508A1 (en) * | 2008-08-18 | 2010-02-25 | David Leppert | Compounds for the treatment of peripheral neuropathies |
EP2177521A1 (en) | 2008-10-14 | 2010-04-21 | Almirall, S.A. | New 2-Amidothiadiazole Derivatives |
RU2011129229A (ru) * | 2008-12-18 | 2013-01-27 | Новартис Аг | Новые соли |
IL294514A (en) * | 2008-12-18 | 2022-09-01 | Novartis Ag | 1-[4-[1[(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-ethyl-benzyl]-azetidine-3-carboxylic acid mipomarate salt |
CA2746764A1 (en) * | 2008-12-18 | 2010-06-24 | Novartis Ag | New polymorphic form of 1- (4- { l- [ (e) -4-cyclohexyl--3-trifluoromethyl-benzyloxyimino] -ethyl) -2-ethyl-benzy l) -azetidine-3-carboxylic |
EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
EP2210890A1 (en) | 2009-01-19 | 2010-07-28 | Almirall, S.A. | Oxadiazole derivatives as S1P1 receptor agonists |
EP2305660A1 (en) | 2009-09-25 | 2011-04-06 | Almirall, S.A. | New thiadiazole derivatives |
US20110124605A1 (en) * | 2009-11-20 | 2011-05-26 | Shreeram Aradhye | Use of an S1P Receptor Agonist |
JP5939158B2 (ja) * | 2009-11-24 | 2016-06-22 | アラーガン、インコーポレイテッドAllergan,Incorporated | 治療的有用性を有する受容体調節物質としての新規化合物 |
EP2343287A1 (en) | 2009-12-10 | 2011-07-13 | Almirall, S.A. | New 2-aminothiadiazole derivatives |
EP2366702A1 (en) | 2010-03-18 | 2011-09-21 | Almirall, S.A. | New oxadiazole derivatives |
EP2390252A1 (en) | 2010-05-19 | 2011-11-30 | Almirall, S.A. | New pyrazole derivatives |
MX371290B (es) | 2011-01-07 | 2020-01-24 | Novartis Ag | Formulaciones inmunosupresoras. |
CN102120720B (zh) * | 2011-01-25 | 2013-05-22 | 上海华升生物科技有限公司 | 盐酸芬戈莫德的合成新方法 |
AU2012324867B2 (en) * | 2011-10-21 | 2015-09-10 | Novartis Ag | Dosage regimen for an S1P receptor modulator or agonist |
BR112014022171B1 (pt) * | 2012-03-23 | 2022-09-20 | Nec Corporation | Servidor de assinante doméstico, servidor de monitoramento, método executado por um servidor de assinante doméstico |
RU2506949C1 (ru) * | 2012-06-13 | 2014-02-20 | Открытое акционерное общество "Новосибхимфарм" | Фармацевтическая композиция агониста рецептора s1p для лечения демиелинизационных заболеваний |
CN102887829B (zh) * | 2012-09-05 | 2014-07-02 | 中国科学院上海药物研究所 | 芬戈莫德粘酸盐及其晶体的制备方法和用途 |
KR101820330B1 (ko) * | 2013-10-11 | 2018-01-19 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 국소 스핑고신-1-포스페이트 수용체 효현제 제형 및 이의 사용 방법 |
WO2015053879A1 (en) | 2013-10-11 | 2015-04-16 | Teikoku Pharma Usa, Inc. | Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same |
US20180042895A1 (en) | 2015-02-26 | 2018-02-15 | Novartis Ag | Treatment of autoimmune disease in a patient receiving additionally a beta-blocker |
US20190047951A1 (en) | 2016-01-04 | 2019-02-14 | Auspex Pharmaceuticals, Inc. | Azetidine modulators of the sphingosine 1-phosphate receptor |
US11434200B2 (en) | 2017-03-09 | 2022-09-06 | Novartis Ag | Solid forms comprising an oxime ether compound and a coformer, compositions and methods of use thereof |
US11629124B2 (en) | 2017-03-09 | 2023-04-18 | Novartis Ag | Solid forms comprising an oxime ether compound, compositions and methods of use thereof |
CN114599363A (zh) | 2019-10-31 | 2022-06-07 | 爱杜西亚药品有限公司 | Cxcr7拮抗剂与s1p1受体调节剂的组合 |
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CL2004001120A1 (es) | 2003-05-19 | 2005-04-15 | Irm Llc | Compuestos derivados de amina sustituidas con heterociclos, inmunosupresores; composicion farmaceutica; y uso para tratar enfermedades mediadas por interacciones de linfocito, tales como enfermedades autoinmunes, inflamatorias, infecciosas, cancer. |
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SI1819358T1 (sl) * | 2004-11-18 | 2014-10-30 | Imclone Llc | Protitelesa proti receptorju 1 za vaskularni endotelijski rastni dejavnik (vegfr-1) |
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GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
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-
2006
- 2006-06-27 GB GBGB0612721.1A patent/GB0612721D0/en not_active Ceased
-
2007
- 2007-06-25 AU AU2007264031A patent/AU2007264031C1/en active Active
- 2007-06-25 KR KR1020217001928A patent/KR20210010956A/ko not_active Application Discontinuation
- 2007-06-25 KR KR1020197007465A patent/KR20190030776A/ko active Search and Examination
- 2007-06-25 ES ES15177166T patent/ES2887042T3/es active Active
- 2007-06-25 DK DK15177166.4T patent/DK2959894T3/da active
- 2007-06-25 CA CA2653569A patent/CA2653569C/en active Active
- 2007-06-25 EP EP15177166.4A patent/EP2959894B1/en active Active
- 2007-06-25 EP EP20208442.2A patent/EP3797765A1/en not_active Withdrawn
- 2007-06-25 WO PCT/EP2007/005597 patent/WO2008000419A1/en active Application Filing
- 2007-06-25 HU HUE15177166A patent/HUE059922T4/hu unknown
- 2007-06-25 SI SI200732191T patent/SI2959894T1/sl unknown
- 2007-06-25 CN CN201310446846.3A patent/CN103550195A/zh active Pending
- 2007-06-25 PT PT151771664T patent/PT2959894T/pt unknown
- 2007-06-25 EP EP07764828A patent/EP2037906A1/en not_active Withdrawn
- 2007-06-25 KR KR1020157030213A patent/KR20150122812A/ko not_active Application Discontinuation
- 2007-06-25 KR KR1020097001390A patent/KR20090024281A/ko not_active Application Discontinuation
- 2007-06-25 KR KR1020147010290A patent/KR20140069178A/ko active Application Filing
- 2007-06-25 LT LTEP2959894T patent/LT2959894T/lt unknown
- 2007-06-25 RU RU2009102278A patent/RU2617502C2/ru active
- 2007-06-25 BR BRPI0713985-3A patent/BRPI0713985A2/pt not_active Application Discontinuation
- 2007-06-25 JP JP2009516964A patent/JP2009541386A/ja active Pending
- 2007-06-25 CN CN2007800236012A patent/CN101478961B/zh not_active Expired - Fee Related
- 2007-06-25 PL PL15177166.4T patent/PL2959894T3/pl unknown
- 2007-06-25 US US12/303,765 patent/US20100168078A1/en not_active Abandoned
- 2007-06-25 MX MX2008016133A patent/MX2008016133A/es not_active Application Discontinuation
- 2007-06-25 DE DE15177166.4T patent/DE15177166T1/de active Pending
- 2007-06-25 KR KR1020177034918A patent/KR20170138583A/ko not_active Application Discontinuation
- 2007-06-25 EP EP13186359.9A patent/EP2698154A1/en not_active Withdrawn
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2008
- 2008-12-16 MX MX2019012750A patent/MX2019012750A/es unknown
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2011
- 2011-04-21 AU AU2011201844A patent/AU2011201844B2/en active Active
- 2011-05-31 US US13/149,468 patent/US8741963B2/en active Active
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2013
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2014
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2016
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- 2016-12-01 AU AU2016266058A patent/AU2016266058A1/en not_active Abandoned
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2018
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2019
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2021
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