SI1803440T1 - Farmacevtski pripravek, ki vsebuje mikrokapsule statinov suspendiranih v alkilnih estrih polinenasičenih maščobnih kislin (PUFA) - Google Patents
Farmacevtski pripravek, ki vsebuje mikrokapsule statinov suspendiranih v alkilnih estrih polinenasičenih maščobnih kislin (PUFA)Info
- Publication number
- SI1803440T1 SI1803440T1 SI200531074T SI200531074T SI1803440T1 SI 1803440 T1 SI1803440 T1 SI 1803440T1 SI 200531074 T SI200531074 T SI 200531074T SI 200531074 T SI200531074 T SI 200531074T SI 1803440 T1 SI1803440 T1 SI 1803440T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pufa
- microcapsules
- alkyl esters
- polyunsaturated fatty
- asids
- Prior art date
Links
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title abstract 2
- 125000005907 alkyl ester group Chemical group 0.000 title abstract 2
- 239000003094 microcapsule Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A61K9/5057—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200402492A ES2255426B1 (es) | 2004-10-19 | 2004-10-19 | Formulacion farmaceutica que comprende microcapsulas de estatinas suspendidas en ester alquilicos de acidos grasos poliinsaturados (pufa). |
| PCT/ES2005/000542 WO2006045865A1 (es) | 2004-10-19 | 2005-10-13 | Formulación farmacéutica que comprende microcapsulas de estatinas suspendidas en ester alquílicos de ácidos grasos poliinsaturados (pufa) |
| EP05802903A EP1803440B1 (en) | 2004-10-19 | 2005-10-13 | Pharmaceutical formulation comprising microcapsules of statins suspended in alkyl esters of polyunsaturated fatty asids (pufa) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1803440T1 true SI1803440T1 (sl) | 2010-10-29 |
Family
ID=36227494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200531074T SI1803440T1 (sl) | 2004-10-19 | 2005-10-13 | Farmacevtski pripravek, ki vsebuje mikrokapsule statinov suspendiranih v alkilnih estrih polinenasičenih maščobnih kislin (PUFA) |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20090196920A1 (sl) |
| EP (1) | EP1803440B1 (sl) |
| JP (1) | JP4976302B2 (sl) |
| KR (1) | KR101413339B1 (sl) |
| CN (2) | CN102727462A (sl) |
| AT (1) | ATE469641T1 (sl) |
| AU (1) | AU2005298587B2 (sl) |
| BR (1) | BRPI0516152A (sl) |
| CA (1) | CA2583756C (sl) |
| CY (1) | CY1110751T1 (sl) |
| DE (1) | DE602005021668D1 (sl) |
| DK (1) | DK1803440T3 (sl) |
| EA (1) | EA012371B1 (sl) |
| ES (2) | ES2255426B1 (sl) |
| IL (1) | IL182466A (sl) |
| MX (1) | MX2007004655A (sl) |
| NZ (1) | NZ554265A (sl) |
| PL (1) | PL1803440T3 (sl) |
| PT (1) | PT1803440E (sl) |
| SI (1) | SI1803440T1 (sl) |
| WO (1) | WO2006045865A1 (sl) |
| ZA (1) | ZA200703509B (sl) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0610344A2 (pt) | 2005-12-13 | 2016-11-29 | Teva Pharma | forma cristalizada do atorvastatin hemi-calcium, processo para sua preparação, produto famacêutico derivado e seu uso medicinal |
| US8784886B2 (en) | 2006-03-09 | 2014-07-22 | GlaxoSmithKline, LLC | Coating capsules with active pharmaceutical ingredients |
| EP2018153B1 (en) | 2006-04-26 | 2012-04-11 | Rosemont Pharmaceuticals Ltd | Liquid oral compositions |
| WO2008000731A2 (en) * | 2006-06-26 | 2008-01-03 | Valpharma S.A. | Pharmaceutical composition for the oral administration of omega polyenoic fatty acids |
| CA2654529A1 (en) * | 2006-07-06 | 2008-01-10 | Teva Pharmaceutical Industries Ltd. | Compositions with controlled pharmacokinetics |
| ITMI20072142A1 (it) | 2007-11-08 | 2009-05-09 | Yervant Zarmanian | Composizioni farmaceutiche contenenti statine e derivati di acidi grassi omega-3 |
| GB0724735D0 (en) | 2007-12-19 | 2008-01-30 | Psynova Neurotech Ltd | Methods and biomarkers for diagnosing and monitoring psychotic disorders |
| NZ587019A (en) * | 2008-01-10 | 2012-07-27 | Takeda Pharmaceutical | Capsule formulation |
| GB0818473D0 (en) | 2008-10-08 | 2008-11-12 | Probio Nutraceuticals As | Composition |
| GB0818472D0 (en) * | 2008-10-08 | 2008-11-12 | Probio Nutraceuticals As | Composition |
| ITFI20080243A1 (it) * | 2008-12-15 | 2010-06-16 | Valpharma Sa | Formulazioni per la somministrazione orale di acidi grassi omega polienoici in combinazione con statine di origine naturale o semi-sintetica. |
| NZ624963A (en) | 2009-04-29 | 2016-07-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| ES2364011B1 (es) * | 2009-11-20 | 2013-01-24 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares. |
| ES2363964B1 (es) * | 2009-11-20 | 2012-08-22 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados. |
| ES2363965B1 (es) * | 2009-11-20 | 2013-01-24 | Gp Pharm S.A. | Cápsulas de principios activos betabloqueantes y ésteres de ácidos grasos poliinsaturados. |
| EP2517697B1 (en) * | 2009-12-23 | 2015-01-07 | Sigma-Tau Industrie Farmaceutiche Riunite SpA | Combination composition useful for treating cardiovascular diseases |
| CA3065589C (en) | 2010-06-03 | 2022-04-26 | Catalent Ontario Limited | Multi phase soft gel capsules, apparatus and method thereof |
| CA2706270C (en) * | 2010-06-03 | 2020-01-07 | Accucaps Industries Limited | Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation |
| JP5829607B2 (ja) | 2010-06-30 | 2015-12-09 | 持田製薬株式会社 | ω３脂肪酸の配合製剤 |
| US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
| US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
| US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| AU2011336856A1 (en) | 2010-11-29 | 2013-07-04 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| KR101310710B1 (ko) * | 2011-03-23 | 2013-09-27 | 한미약품 주식회사 | 오메가-3 지방산 에스테르 및 ＨＭＧ-ＣｏＡ 환원효소 억제제를 포함하는 경구용 복합 조성물 |
| WO2012170417A2 (en) | 2011-06-06 | 2012-12-13 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
| KR101466617B1 (ko) * | 2011-11-17 | 2014-11-28 | 한미약품 주식회사 | 오메가-3 지방산 및 HMG-CoA 환원효소 억제제를 포함하는 안정성이 증가된 경구용 복합 제제 |
| EP2846779A4 (en) * | 2012-05-07 | 2015-12-16 | Omthera Pharmaceuticals Inc | STATIN AND OMEGA-3 FATTY ACID COMPOSITIONS |
| AU2013264518B2 (en) | 2012-05-22 | 2016-02-11 | Kuhnil Pharm. Co., Ltd. | Multilayer coating form of orally administered pharmaceutical composition containing omega-3 fatty acid or alkyl ester thereof and statin based drug |
| CN102824636A (zh) * | 2012-08-15 | 2012-12-19 | 四川大学 | 一种含他汀类药物和多不饱和脂肪酸的药物组合物及其用途 |
| WO2014182003A1 (en) * | 2013-05-06 | 2014-11-13 | Hanmi Pharm. Co., Ltd. | Composite formulation comprising a film coating layer containing rosuvastatin or a pharmaceutically acceptable salt thereof |
| KR102240429B1 (ko) * | 2013-05-06 | 2021-04-15 | 한미약품 주식회사 | 로수바스타틴 또는 이의 약학적으로 허용되는 염이 함유된 필름 코팅층을 포함하는 복합 제형 |
| WO2015185240A1 (en) | 2014-06-04 | 2015-12-10 | Sigma-Tau Industrire Farmaceutiche Riunite S.P.A. | Compositions containing simvastatin in omega-3 polyunsaturated fatty acids |
| RU2614734C2 (ru) * | 2015-05-21 | 2017-03-28 | Татьяна Алексеевна Денисюк | Способ получения нанокапсул розувастатина в каррагинане |
| KR101950907B1 (ko) | 2016-02-05 | 2019-02-21 | 한국유나이티드제약 주식회사 | 지용성 약물 및 방유성 기제가 코팅된 고형제제를 포함하는 경구용 복합제제 |
| WO2019143981A1 (en) * | 2018-01-19 | 2019-07-25 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for delivering pharmaceutical agents |
| MA51765A (fr) | 2018-09-24 | 2020-12-16 | Amarin Pharmaceuticals Ie Ltd | Procédés de réduction du risque d'événements cardiovasculaires chez un sujet |
| WO2022129002A1 (en) * | 2020-12-15 | 2022-06-23 | Dsm Ip Assets B.V. | Coarse dispersion comprising statin and vitamin e oil |
| US11986452B2 (en) | 2021-04-21 | 2024-05-21 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing the risk of heart failure |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5312473B1 (sl) | 1971-05-24 | 1978-05-01 | ||
| PH19942A (en) | 1980-11-18 | 1986-08-14 | Sintex Inc | Microencapsulation of water soluble polypeptides |
| JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| GB2209937B (en) | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
| US5180589A (en) | 1988-03-31 | 1993-01-19 | E. R. Squibb & Sons, Inc. | Pravastatin pharmaceuatical compositions having good stability |
| US5035896A (en) | 1988-06-15 | 1991-07-30 | Warner-Lambert Company | Water insoluble drugs coated by coacervated fish gelatin |
| CH683149A5 (fr) * | 1991-07-22 | 1994-01-31 | Debio Rech Pharma Sa | Procédé pour la préparation de microsphères en matériau polymère biodégradable. |
| US5225202A (en) | 1991-09-30 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Enteric coated pharmaceutical compositions |
| HU9203780D0 (en) * | 1991-12-12 | 1993-03-29 | Sandoz Ag | Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them |
| US5861399A (en) * | 1996-07-17 | 1999-01-19 | Heart Care Partners | Methods and compositions for the rapid and enduring relief of inadequate myocardial function |
| US6235311B1 (en) | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
| WO2000057918A2 (en) | 1999-03-31 | 2000-10-05 | Abbott Laboratories | Novel formulations comprising lipid-regulating agents |
| MXPA01009840A (es) | 1999-03-31 | 2002-06-21 | Abbott Lab | Nuevas formulaciones que comprenden agentes reguladores de lipido. |
| US6372251B2 (en) | 1999-06-11 | 2002-04-16 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
| US7208180B2 (en) * | 2000-05-08 | 2007-04-24 | N.V. Nutricia | Method and preparation for the preventing and/or treating vascular disorders and secondary disorders associated therewith |
| US6667064B2 (en) * | 2000-08-30 | 2003-12-23 | Pilot Therapeutics, Inc. | Composition and method for treatment of hypertriglyceridemia |
| CA2427618A1 (en) * | 2000-11-29 | 2002-06-06 | Smithkline Beecham Corporation | Composition containing statins and calcium for improved cardiovascular health |
| DE60219307T2 (de) * | 2001-06-12 | 2008-01-10 | Galephar M/F | Oral anzuwendende arzneizusammensetzung enthaltend ein statinderivat |
| CA2456034A1 (en) * | 2001-08-03 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Sustained-release medicines |
| JP4831965B2 (ja) * | 2002-06-10 | 2011-12-07 | エラン ファーマ インターナショナル，リミティド | ＨＭＧ−ＣｏＡ還元酵素インヒビター誘導体（「スタチン」）を含むナノ粒子製剤、その新規組合せ、ならびにこれらの医薬組成物の製造 |
| GB0217306D0 (en) * | 2002-07-25 | 2002-09-04 | Novartis Ag | Compositions comprising organic compounds |
| EP2283838A3 (en) * | 2002-09-27 | 2011-04-20 | Martek Biosciences Corporation | Docosahexaenoic acid for treating subclinical inflammation |
| ES2665464T3 (es) * | 2003-03-28 | 2018-04-25 | Sigmoid Pharma Limited | Forma de dosificación oral sólida que contiene microcápsulas sin costuras |
-
2004
- 2004-10-19 ES ES200402492A patent/ES2255426B1/es not_active Expired - Fee Related
-
2005
- 2005-10-13 PL PL05802903T patent/PL1803440T3/pl unknown
- 2005-10-13 EP EP05802903A patent/EP1803440B1/en not_active Not-in-force
- 2005-10-13 DE DE602005021668T patent/DE602005021668D1/de active Active
- 2005-10-13 PT PT05802903T patent/PT1803440E/pt unknown
- 2005-10-13 AT AT05802903T patent/ATE469641T1/de active
- 2005-10-13 KR KR1020077008798A patent/KR101413339B1/ko not_active IP Right Cessation
- 2005-10-13 AU AU2005298587A patent/AU2005298587B2/en not_active Ceased
- 2005-10-13 ES ES05802903T patent/ES2347055T3/es active Active
- 2005-10-13 JP JP2007537313A patent/JP4976302B2/ja not_active Expired - Fee Related
- 2005-10-13 BR BRPI0516152-5A patent/BRPI0516152A/pt active Search and Examination
- 2005-10-13 CA CA2583756A patent/CA2583756C/en not_active Expired - Fee Related
- 2005-10-13 NZ NZ554265A patent/NZ554265A/en not_active IP Right Cessation
- 2005-10-13 ZA ZA200703509A patent/ZA200703509B/xx unknown
- 2005-10-13 CN CN2012100736124A patent/CN102727462A/zh active Pending
- 2005-10-13 CN CNA2005800357056A patent/CN101043873A/zh active Pending
- 2005-10-13 MX MX2007004655A patent/MX2007004655A/es active IP Right Grant
- 2005-10-13 SI SI200531074T patent/SI1803440T1/sl unknown
- 2005-10-13 DK DK05802903.4T patent/DK1803440T3/da active
- 2005-10-13 US US11/665,665 patent/US20090196920A1/en not_active Abandoned
- 2005-10-13 WO PCT/ES2005/000542 patent/WO2006045865A1/es active Application Filing
- 2005-10-13 EA EA200700614A patent/EA012371B1/ru not_active IP Right Cessation
-
2007
- 2007-04-11 IL IL182466A patent/IL182466A/en not_active IP Right Cessation
-
2010
- 2010-08-30 CY CY20101100790T patent/CY1110751T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2347055T3 (es) | 2010-10-25 |
| ZA200703509B (en) | 2008-09-25 |
| US20090196920A1 (en) | 2009-08-06 |
| JP2008517040A (ja) | 2008-05-22 |
| CA2583756A1 (en) | 2006-05-04 |
| EP1803440A1 (en) | 2007-07-04 |
| KR20070083715A (ko) | 2007-08-24 |
| JP4976302B2 (ja) | 2012-07-18 |
| CN102727462A (zh) | 2012-10-17 |
| DK1803440T3 (da) | 2010-10-04 |
| AU2005298587B2 (en) | 2010-08-05 |
| ATE469641T1 (de) | 2010-06-15 |
| EP1803440B1 (en) | 2010-06-02 |
| ES2255426A1 (es) | 2006-06-16 |
| WO2006045865A1 (es) | 2006-05-04 |
| KR101413339B1 (ko) | 2014-06-27 |
| PL1803440T3 (pl) | 2010-12-31 |
| DE602005021668D1 (de) | 2010-07-15 |
| CA2583756C (en) | 2013-12-24 |
| IL182466A (en) | 2013-06-27 |
| BRPI0516152A (pt) | 2008-08-26 |
| MX2007004655A (es) | 2008-03-10 |
| IL182466A0 (en) | 2007-07-24 |
| ES2255426B1 (es) | 2007-08-16 |
| PT1803440E (pt) | 2010-08-31 |
| CY1110751T1 (el) | 2015-06-10 |
| EA012371B1 (ru) | 2009-10-30 |
| NZ554265A (en) | 2010-12-24 |
| CN101043873A (zh) | 2007-09-26 |
| AU2005298587A1 (en) | 2006-05-04 |
| EA200700614A1 (ru) | 2007-10-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL1803440T3 (pl) | Preparat farmaceutyczny zawierający mikrokapsułki statyn w zawiesinie w estrach alkilowych wielonienasyconych kwasów tłuszczowych (PUFA) | |
| EP2602308A3 (en) | Lipase-catalysed esterification of marine oil | |
| AP2230A (en) | Improved process for the preparation of fatty acidmethyl ester (biodiesel) from triglyceride oil th rough transesterification. | |
| EP2679687A3 (en) | Fatty acid blends and uses therefor | |
| NO990739D0 (no) | Lipase-katalysert esterifikasjon av marine oljer | |
| UY29194A1 (es) | Composiciones de aceites ricos en acidos grasos poliinsaturados (pufa) | |
| WO2008011468A3 (en) | Fatty acid desaturases from tetraselmis suecica | |
| EP1787532A3 (en) | Microbial oil mixtures and uses thereof | |
| ATE538658T1 (de) | Ölzusammensetzung aus konjugierter linolsäure | |
| BR0209749A (pt) | Coenzima q e epa ou outro ácido graxo essencial | |
| EP2510927A3 (en) | Use of dha, epa or dha-derived epa for treating a pathology associated with cellular oxidative damage | |
| BRPI0416403A (pt) | composição de óleo enriquecida em diglicerìdeo com ácido linoléico conjugado | |
| ATE422350T1 (de) | Anisinsäure und glyceride enthaltende zusammensetzungen | |
| FR2903014B1 (fr) | Composition cosmetique a base d'acide gras polyinsatures et ses utilisations | |
| ATE384518T1 (de) | Zusammensetzungen enthaltend phytosterol- und policosanolester von fettsäuren zur herabsetzung des cholesterol- und triglyceridspiegels | |
| BRPI0515958A (pt) | composição agroquìmica contendo éster de ácido fosfórico | |
| AU2614200A (en) | Composition for stabilizing and potentiating the action of anti-angiogenic substances by polyunsaturated fatty acids | |
| TR199801519T2 (xx) | Yenebilir bitkisel ya� bile�imi. | |
| EP1718156A4 (en) | COMPOSITIONS AND METHODS FOR ALTERING POLYUNSATURATED FATTY ACID CONTENT OF BIOLOGICAL CELLS | |
| WO2009059717A3 (en) | Pharmaceutical compositions containing statins and omega-3 fatty acids derivatives and their solid formulations for oral use | |
| AU2003222739A1 (en) | A facile two-step enzyme process for increasing the content of polyunsaturated fatty acids in fish oil | |
| DE69607247D1 (de) | Hydraulische Flüssigkeitzusammensetzung | |
| HK1043605A1 (zh) | 從含有亞油酸或其酯的混合物製備富羥基十八碳二烯脂肪酸或其酯的油的方法 | |
| AR048014A1 (es) | Aceite de girasol con distribucion modificada de acidos grasos en la molecula de triacilglicerol | |
| EA200870059A1 (ru) | Производные хитина для применения при гиперлипидемии |