SI1150966T1 - Method for the preparation of 5-cyanophthalide - Google Patents

Method for the preparation of 5-cyanophthalide

Info

Publication number
SI1150966T1
SI1150966T1 SI200030024T SI200030024T SI1150966T1 SI 1150966 T1 SI1150966 T1 SI 1150966T1 SI 200030024 T SI200030024 T SI 200030024T SI 200030024 T SI200030024 T SI 200030024T SI 1150966 T1 SI1150966 T1 SI 1150966T1
Authority
SI
Slovenia
Prior art keywords
cyanophthalide
preparation
Prior art date
Application number
SI200030024T
Other languages
English (en)
Slovenian (sl)
Inventor
Beat Weber
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of SI1150966T1 publication Critical patent/SI1150966T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SI200030024T 1999-01-29 2000-01-26 Method for the preparation of 5-cyanophthalide SI1150966T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199900128 1999-01-29
PCT/DK2000/000032 WO2000044738A1 (en) 1999-01-29 2000-01-26 Method for the preparation of 5-cyanophthalide
EP00901482A EP1150966B1 (en) 1999-01-29 2000-01-26 Method for the preparation of 5-cyanophthalide

Publications (1)

Publication Number Publication Date
SI1150966T1 true SI1150966T1 (en) 2003-02-28

Family

ID=8090069

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030024T SI1150966T1 (en) 1999-01-29 2000-01-26 Method for the preparation of 5-cyanophthalide

Country Status (31)

Country Link
US (1) US6441201B1 (is)
EP (1) EP1150966B1 (is)
JP (1) JP2002535397A (is)
KR (1) KR100430327B1 (is)
CN (1) CN1158271C (is)
AR (1) AR022329A1 (is)
AT (1) ATE222900T1 (is)
AU (1) AU763666B2 (is)
BG (1) BG64924B1 (is)
BR (1) BR0008978A (is)
CA (1) CA2361395C (is)
CZ (1) CZ300257B6 (is)
DE (1) DE60000364T2 (is)
DK (1) DK1150966T3 (is)
EA (1) EA003257B1 (is)
ES (1) ES2180508T3 (is)
HK (1) HK1044342B (is)
HU (1) HUP0104976A3 (is)
IL (2) IL144114A0 (is)
IS (1) IS2223B (is)
IT (1) IT1317741B1 (is)
NO (1) NO326532B1 (is)
NZ (1) NZ512775A (is)
PL (1) PL198385B1 (is)
PT (1) PT1150966E (is)
SI (1) SI1150966T1 (is)
SK (1) SK284367B6 (is)
TR (1) TR200102135T2 (is)
UA (1) UA70987C2 (is)
WO (1) WO2000044738A1 (is)
ZA (1) ZA200105549B (is)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
EA003057B1 (ru) 1998-12-23 2002-12-26 Х.Лундбекк А/С Способ получения 5-цианофталида
CN1142926C (zh) 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
EP1228056B1 (en) 1999-10-25 2004-09-22 H. Lundbeck A/S Method for the preparation of citalopram
PT1298124E (pt) 1999-10-25 2007-05-31 Lundbeck & Co As H Método para a preparação de citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
PT1246812E (pt) 1999-12-28 2004-08-31 Lundbeck & Co As H Metodo para a preparacao de citalopram
EP1246813B1 (en) 1999-12-30 2003-11-05 H. Lundbeck A/S Method for the preparation of citalopram
ATE252570T1 (de) 2000-01-14 2003-11-15 Lundbeck & Co As H Verfahren zur herstellung von 5-cyanophthalid
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EP1265881A1 (en) 2000-03-13 2002-12-18 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
EA200200982A1 (ru) * 2000-03-16 2003-02-27 Х.Лундбекк А/С Способ получения 5-циано-1-(4-фторфенил)-1,3-дигидроизобензофуранов
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144816A (en) * 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
CA2360303C (en) 2000-12-22 2003-08-12 Marco Villa Process for the preparation of pure citalopram
PT1181272E (pt) 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro
GR1004635B (el) * 2001-08-14 2004-07-14 H@Αlundbeckαa@Sαα Μεθοδοσαπαρασκευησατησασιταλοπραμης@αα
EP1321464A1 (en) * 2001-12-21 2003-06-25 ICROM S.p.A. Process for the preparation of 5-cyanophthalide and intermediates useful therein
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
US7687645B2 (en) 2003-03-21 2010-03-30 H. Lundbeck A/S Intermediates for the preparation of citalopram and escitalopram
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
EP1777221A1 (en) * 2005-10-14 2007-04-25 Adorkem Technology SpA Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (is) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
DE1015416T1 (de) 1997-07-08 2000-10-05 Lundbeck A S Kobenhavn Valby H Verfahren zur herstellung von citalopram
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
JP3813820B2 (ja) 1997-11-11 2006-08-23 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
EA003057B1 (ru) * 1998-12-23 2002-12-26 Х.Лундбекк А/С Способ получения 5-цианофталида
CN1142926C (zh) 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
EP1228056B1 (en) 1999-10-25 2004-09-22 H. Lundbeck A/S Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
CA2360303C (en) 2000-12-22 2003-08-12 Marco Villa Process for the preparation of pure citalopram
PT1181272E (pt) 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro

Also Published As

Publication number Publication date
TR200102135T2 (tr) 2002-01-21
EA200100834A1 (ru) 2001-12-24
CN1337957A (zh) 2002-02-27
ATE222900T1 (de) 2002-09-15
US6441201B1 (en) 2002-08-27
IS2223B (is) 2007-03-15
JP2002535397A (ja) 2002-10-22
AU2278200A (en) 2000-08-18
EP1150966A1 (en) 2001-11-07
ZA200105549B (en) 2002-07-05
IT1317741B1 (it) 2003-07-15
DE60000364D1 (de) 2002-10-02
HK1044342B (zh) 2005-04-22
SK284367B6 (sk) 2005-02-04
HUP0104976A3 (en) 2002-09-30
EA003257B1 (ru) 2003-02-27
US20020028956A1 (en) 2002-03-07
CZ300257B6 (cs) 2009-04-01
NZ512775A (en) 2003-11-28
BG105692A (en) 2002-02-28
NO326532B1 (no) 2008-12-29
CA2361395C (en) 2005-11-15
IL144114A (en) 2006-06-11
PL198385B1 (pl) 2008-06-30
WO2000044738A1 (en) 2000-08-03
CZ20012734A3 (cs) 2002-01-16
NO20013667L (no) 2001-07-26
IS5982A (is) 2001-06-28
UA70987C2 (uk) 2004-11-15
HK1044342A1 (en) 2002-10-18
CA2361395A1 (en) 2000-08-03
DE60000364T2 (de) 2003-04-03
HUP0104976A2 (en) 2002-06-29
EP1150966B1 (en) 2002-08-28
KR20010101432A (ko) 2001-11-14
ES2180508T3 (es) 2003-02-16
AU763666B2 (en) 2003-07-31
ITMI20000112A0 (it) 2000-01-27
IL144114A0 (en) 2002-05-23
ITMI20000112A1 (it) 2001-07-27
SK10562001A3 (sk) 2002-01-07
KR100430327B1 (ko) 2004-05-03
BG64924B1 (bg) 2006-09-29
AR022329A1 (es) 2002-09-04
BR0008978A (pt) 2001-11-27
PT1150966E (pt) 2003-01-31
NO20013667D0 (no) 2001-07-26
DK1150966T3 (da) 2002-12-30
CN1158271C (zh) 2004-07-21
PL349908A1 (en) 2002-10-07

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