SI0912613T1 - Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same - Google Patents

Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same

Info

Publication number
SI0912613T1
SI0912613T1 SI9730424T SI9730424T SI0912613T1 SI 0912613 T1 SI0912613 T1 SI 0912613T1 SI 9730424 T SI9730424 T SI 9730424T SI 9730424 T SI9730424 T SI 9730424T SI 0912613 T1 SI0912613 T1 SI 0912613T1
Authority
SI
Slovenia
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
method therefor
containing same
Prior art date
Application number
SI9730424T
Other languages
English (en)
Slovenian (sl)
Inventor
Pierre Alexandre Driguez
Philippe Duchaussoy
Jean-Marc Herbert
Maurice Petitou
Boeckel Constant Van
Peter Grootenhuis
Cornelia Dreef-Tromp
Johannes Basten
Original Assignee
Sanofi-Synthelabo
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo, Akzo Nobel N.V. filed Critical Sanofi-Synthelabo
Publication of SI0912613T1 publication Critical patent/SI0912613T1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9730424T 1996-07-19 1997-07-18 Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same SI0912613T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9609116A FR2751334B1 (fr) 1996-07-19 1996-07-19 Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
EP97934596A EP0912613B1 (fr) 1996-07-19 1997-07-18 Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
PCT/FR1997/001344 WO1998003554A1 (fr) 1996-07-19 1997-07-18 Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
SI0912613T1 true SI0912613T1 (en) 2003-04-30

Family

ID=9494266

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9730424T SI0912613T1 (en) 1996-07-19 1997-07-18 Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same

Country Status (36)

Country Link
US (1) US6534481B1 (cs)
EP (1) EP0912613B1 (cs)
JP (1) JP3345020B2 (cs)
KR (1) KR100311857B1 (cs)
CN (1) CN1200003C (cs)
AR (1) AR008068A1 (cs)
AT (1) ATE224917T1 (cs)
AU (1) AU726679B2 (cs)
BR (1) BR9710739B1 (cs)
CA (1) CA2261597C (cs)
CZ (1) CZ301009B6 (cs)
DE (1) DE69715866T2 (cs)
DK (1) DK0912613T3 (cs)
EE (1) EE03929B1 (cs)
ES (1) ES2184123T3 (cs)
FR (1) FR2751334B1 (cs)
HK (1) HK1019757A1 (cs)
HU (1) HU223691B1 (cs)
ID (1) ID20604A (cs)
IL (2) IL128018A0 (cs)
IS (1) IS1968B (cs)
MY (1) MY124548A (cs)
NO (1) NO319682B1 (cs)
NZ (1) NZ333721A (cs)
PL (1) PL190397B1 (cs)
PT (1) PT912613E (cs)
RU (1) RU2167163C2 (cs)
SA (1) SA99200037B1 (cs)
SI (1) SI0912613T1 (cs)
SK (1) SK284881B6 (cs)
TR (1) TR199900114T2 (cs)
TW (1) TW520376B (cs)
UA (1) UA61921C2 (cs)
WO (1) WO1998003554A1 (cs)
YU (1) YU49247B (cs)
ZA (1) ZA976340B (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2773801B1 (fr) * 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
US7138531B2 (en) * 2001-10-15 2006-11-21 Kemin Pharma B.V.B.A. Preparation and use of carbohydrate-based bicyclic ring structures with antimicrobial and cytostatic activity
EP1574516A1 (en) * 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
US7563780B1 (en) * 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
FR2874924B1 (fr) * 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
IL181431A0 (en) * 2007-02-19 2007-07-04 Micha Shemer Fruit juice and puree with a lowered amount of available sugars
MX338213B (es) 2007-10-16 2016-04-07 Progen Pharmaceuticals Ltd Derivados de oligosacaridos sulfatados novedosos.
CN102046781A (zh) 2008-05-30 2011-05-04 动量制药公司 糖结构以及制造和使用此类结构的方法
FR2935386B1 (fr) * 2008-08-26 2010-09-10 Sanofi Aventis Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
EP2464668B1 (en) * 2009-07-31 2022-12-07 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
KR101682466B1 (ko) * 2010-02-01 2016-12-05 롯데정밀화학 주식회사 아세틸화 셀룰로오스 에테르 및 이를 포함하는 물품
JP2013537181A (ja) 2010-09-10 2013-09-30 サノフイ 抗血栓活性及び改善された代謝安定性を有するビオチン化多糖類
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique
CN109134553B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134554B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134555B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801583A (en) 1982-01-15 1989-01-31 Choay S.A. Oligosaccharides and their biological applications
EP0300099A1 (en) 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
US5382570A (en) 1990-04-23 1995-01-17 Akzo, N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
US5378829A (en) 1990-04-23 1995-01-03 Akzo N.V. Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
IL102758A (en) 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
EP0649854B1 (en) 1993-09-01 2000-03-15 Akzo Nobel N.V. Bisconjugates comprising two saccharides and a spacer
FR2749849B1 (fr) * 1996-06-14 1998-09-04 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
EP0912613B1 (fr) 2002-09-25
JP3345020B2 (ja) 2002-11-18
NO990215D0 (no) 1999-01-18
CN1200003C (zh) 2005-05-04
JP2000500807A (ja) 2000-01-25
HUP9902287A3 (en) 2001-09-28
KR100311857B1 (ko) 2001-11-14
HK1019757A1 (en) 2000-02-25
AU3774797A (en) 1998-02-10
IL128018A0 (en) 1999-11-30
YU1999A (sh) 2000-03-21
IL128018A (en) 2007-10-31
PT912613E (pt) 2003-01-31
WO1998003554A1 (fr) 1998-01-29
BR9710739B1 (pt) 2008-11-18
CZ301009B6 (cs) 2009-10-14
NZ333721A (en) 2000-08-25
EE9900015A (et) 1999-08-16
AU726679B2 (en) 2000-11-16
SK284881B6 (sk) 2006-02-02
SK5399A3 (en) 2000-05-16
EP0912613A1 (fr) 1999-05-06
CA2261597A1 (fr) 1998-01-29
KR20000067909A (ko) 2000-11-25
CN1228785A (zh) 1999-09-15
MY124548A (en) 2006-06-30
PL331259A1 (en) 1999-07-05
US6534481B1 (en) 2003-03-18
RU2167163C2 (ru) 2001-05-20
TR199900114T2 (xx) 1999-03-22
BR9710739A (pt) 1999-08-17
DK0912613T3 (da) 2003-01-27
PL190397B1 (pl) 2005-12-30
IS4945A (is) 1999-01-18
HU223691B1 (hu) 2004-12-28
FR2751334A1 (fr) 1998-01-23
FR2751334B1 (fr) 1998-10-16
DE69715866T2 (de) 2003-05-28
HUP9902287A1 (hu) 1999-10-28
IS1968B (is) 2004-12-15
DE69715866D1 (de) 2002-10-31
SA99200037B1 (ar) 2006-08-23
YU49247B (sh) 2004-12-31
TW520376B (en) 2003-02-11
ID20604A (id) 1999-01-21
AR008068A1 (es) 1999-12-09
CZ16099A3 (cs) 1999-06-16
ZA976340B (en) 1999-01-22
ATE224917T1 (de) 2002-10-15
NO319682B1 (no) 2005-09-05
CA2261597C (fr) 2004-12-14
EE03929B1 (et) 2002-12-16
ES2184123T3 (es) 2003-04-01
NO990215L (no) 1999-03-18
UA61921C2 (uk) 2003-12-15

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