SI0871616T1 - Process for the preparation of anti-malarial drugs - Google Patents

Process for the preparation of anti-malarial drugs

Info

Publication number
SI0871616T1
SI0871616T1 SI9630461T SI9630461T SI0871616T1 SI 0871616 T1 SI0871616 T1 SI 0871616T1 SI 9630461 T SI9630461 T SI 9630461T SI 9630461 T SI9630461 T SI 9630461T SI 0871616 T1 SI0871616 T1 SI 0871616T1
Authority
SI
Slovenia
Prior art keywords
preparation
malarial drugs
malarial
drugs
Prior art date
Application number
SI9630461T
Other languages
English (en)
Slovenian (sl)
Inventor
Cletus Onwuzurike SmithKline Beecham UGWUEGBULAM
James Edward SmithKline Beecham FOY
Original Assignee
Smithkline Beecham P.L.C.
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham P.L.C., Smithkline Beecham Corporation filed Critical Smithkline Beecham P.L.C.
Publication of SI0871616T1 publication Critical patent/SI0871616T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9630461T 1995-10-13 1996-10-11 Process for the preparation of anti-malarial drugs SI0871616T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9521004.3A GB9521004D0 (en) 1995-10-13 1995-10-13 Process
PCT/EP1996/004433 WO1997013753A1 (en) 1995-10-13 1996-10-11 Process for the preparation of anti-malarial drugs
EP96934646A EP0871616B1 (en) 1995-10-13 1996-10-11 Process for the preparation of anti-malarial drugs

Publications (1)

Publication Number Publication Date
SI0871616T1 true SI0871616T1 (en) 2002-12-31

Family

ID=10782264

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9630461T SI0871616T1 (en) 1995-10-13 1996-10-11 Process for the preparation of anti-malarial drugs

Country Status (28)

Country Link
US (1) US6479660B1 (xx)
EP (1) EP0871616B1 (xx)
JP (1) JP4083803B2 (xx)
KR (1) KR100453256B1 (xx)
CN (1) CN1147475C (xx)
AR (1) AR004015A1 (xx)
AT (1) ATE214372T1 (xx)
AU (1) AU709333B2 (xx)
BR (1) BR9611010A (xx)
CA (1) CA2231633C (xx)
CZ (1) CZ290380B6 (xx)
DE (1) DE69619863T2 (xx)
DK (1) DK0871616T3 (xx)
ES (1) ES2170874T3 (xx)
GB (1) GB9521004D0 (xx)
HK (1) HK1016180A1 (xx)
HU (1) HUP9900739A3 (xx)
IL (1) IL124060A (xx)
NO (1) NO313285B1 (xx)
NZ (1) NZ320209A (xx)
PL (1) PL186055B1 (xx)
PT (1) PT871616E (xx)
SA (1) SA97170574B1 (xx)
SI (1) SI0871616T1 (xx)
TR (1) TR199800637T2 (xx)
TW (1) TW450950B (xx)
WO (1) WO1997013753A1 (xx)
ZA (1) ZA968550B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08276712A (ja) * 1995-04-05 1996-10-22 Masao Tsuji チュ−ブレススパイクタイヤ
GB0210150D0 (en) * 2002-05-03 2002-06-12 Smithkline Beecham Plc Process
JP2009507824A (ja) * 2005-09-12 2009-02-26 カウンシル・オブ・サイエンティフィック・アンド・インダストリアル・リサーチ 抗マラリアベイリス−ヒルマン付加物およびその調製方法
WO2007127930A2 (en) * 2006-04-28 2007-11-08 Kansas State University Research Foundation Compounds affecting gap junction activity
GB0620005D0 (en) 2006-10-10 2006-11-22 Glaxo Group Ltd Compounds
US20090076072A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched tafenoquine
ES2453206B1 (es) 2013-09-25 2015-01-12 Thyssenkrupp Elevator Innovation Center, S.A. Sistema de tracción para un sistema de transporte
CN113248431A (zh) * 2021-05-21 2021-08-13 重庆医药高等专科学校 一种磷酸伯氨喹的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431807A (en) * 1980-06-12 1984-02-14 The United States Of America As Represented By The Secretary Of The Army 4-Methyl-5-(unsubstituted and substituted phenoxy)-6-methoxy-8-(aminoalkylamino)quinolines
US4617394A (en) * 1985-10-15 1986-10-14 The United States Of America As Represented By The Secretary Of The Army 4-methyl-5-(unsubstituted and substituted phenoxy)-2,6-dimethoxy-8-(aminoalkylamino) quinolines

Also Published As

Publication number Publication date
BR9611010A (pt) 1999-07-13
PL186055B1 (pl) 2003-09-30
ZA968550B (en) 1998-04-14
DE69619863T2 (de) 2002-11-21
GB9521004D0 (en) 1995-12-13
NO981537D0 (no) 1998-04-03
JP4083803B2 (ja) 2008-04-30
CZ290380B6 (cs) 2002-07-17
EP0871616B1 (en) 2002-03-13
ATE214372T1 (de) 2002-03-15
NO313285B1 (no) 2002-09-09
KR100453256B1 (ko) 2004-12-17
HUP9900739A2 (hu) 1999-09-28
CA2231633A1 (en) 1997-04-17
PT871616E (pt) 2002-07-31
JPH11513399A (ja) 1999-11-16
US6479660B1 (en) 2002-11-12
HUP9900739A3 (en) 1999-11-29
AU7291096A (en) 1997-04-30
DK0871616T3 (da) 2002-07-01
IL124060A (en) 2003-07-31
HK1016180A1 (en) 1999-10-29
AR004015A1 (es) 1998-09-30
SA97170574B1 (ar) 2006-09-25
DE69619863D1 (de) 2002-04-18
TW450950B (en) 2001-08-21
NZ320209A (en) 1999-08-30
WO1997013753A1 (en) 1997-04-17
CZ110398A3 (cs) 1998-09-16
NO981537L (no) 1998-04-03
CN1147475C (zh) 2004-04-28
TR199800637T2 (xx) 1998-07-21
CA2231633C (en) 2006-10-03
PL326194A1 (en) 1998-08-31
KR19990064210A (ko) 1999-07-26
CN1199395A (zh) 1998-11-18
ES2170874T3 (es) 2002-08-16
EP0871616A1 (en) 1998-10-21
AU709333B2 (en) 1999-08-26

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