HU195800B
(en)
*
|
1983-10-13 |
1988-07-28 |
Sandoz Ltd |
Process for producing 4h-benzo/4,5/cylopenta/1,2-b/ thiofene derivatives and pharmaceutical compositions containing them
|
HU194864B
(en)
*
|
1984-02-15 |
1988-03-28 |
Schering Corp |
Process for production of 8-chlor-6,11-dihydro-11-(4-piperidilidene)-5h-benzo (5,6)-cyclo-hepta (1,2-b) pyridine and its salts
|
EP0208855B1
(en)
*
|
1985-05-13 |
1991-03-06 |
Schering Corporation |
process for preparing piperidylidene dihydrodibenzo(a,d)cycloheptenes and aza derivatives thereof, compounds obtained by such process and the use of such compounds for preparing useful pharmaceutical compositions
|
US4804666A
(en)
*
|
1985-08-14 |
1989-02-14 |
Schering Corporation |
Antiallergic 6,11-dihydro-11-(4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines
|
US5438062A
(en)
*
|
1986-10-31 |
1995-08-01 |
Schering Corporation |
Benzo(5,6)cycloheptapyridines, compositions and methods of use
|
AU635400B2
(en)
*
|
1986-10-31 |
1993-03-18 |
Schering Corporation |
Intermediates for producing benzo(5,6)cycloheptapyridines
|
US5089496A
(en)
|
1986-10-31 |
1992-02-18 |
Schering Corporation |
Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
|
US4826853A
(en)
*
|
1986-10-31 |
1989-05-02 |
Schering Corporation |
6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use
|
US5665726A
(en)
*
|
1986-10-31 |
1997-09-09 |
Schering Corporation |
Benzo[5,6]cycloheptapyridines, compositions and methods of use
|
EP0411048A1
(en)
*
|
1988-04-28 |
1991-02-06 |
Schering Corporation |
Novel benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use
|
US4912222A
(en)
*
|
1988-06-17 |
1990-03-27 |
Fisons Corporation |
Antihistamines related to cyproheptadine
|
US4863931A
(en)
*
|
1988-09-15 |
1989-09-05 |
Schering Corporation |
Antihistaminic fluoro substituted benzocycloheptapyridines
|
US4990535A
(en)
*
|
1989-05-03 |
1991-02-05 |
Schering Corporation |
Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
|
CA2038417A1
(en)
*
|
1990-04-11 |
1991-10-12 |
Yasuo Ito |
Piperidine compounds, method for preparation thereof, and a pharmaceutical composition comprising the same
|
ZA914764B
(en)
*
|
1990-06-22 |
1992-03-25 |
Schering Corp |
Bis-benzo or benzopyrido cyclohepta piperidene,piperidylidene and piperazine compounds,compositions and methods of use
|
WO1992006970A1
(en)
*
|
1990-10-10 |
1992-04-30 |
Schering Corporation |
Bis-benzo cyclohepta piperidylidene, piperidine and piperazine compounds, compositions and methods of use
|
JPH089616B2
(ja)
*
|
1990-10-10 |
1996-01-31 |
シェリング・コーポレーション |
置換されたイミダゾベンズアゼピン類およびイミダゾピリドアゼピン類
|
WO1992011034A1
(en)
*
|
1990-12-18 |
1992-07-09 |
The Wellcome Foundation Limited |
Agents for potentiating the effects of antitumor agents and combating multiple drug resistance
|
KR920014799A
(ko)
*
|
1991-01-18 |
1992-08-25 |
나오가따 다이도 |
신규벤조[5,6]시클로헵타[1,2-b]피리딘 유도체 및 이를 함유하는 항알레르기제
|
EP0586560A1
(en)
*
|
1991-05-23 |
1994-03-16 |
Schering Corporation |
Novel benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use
|
EP0595989A1
(en)
*
|
1991-07-23 |
1994-05-11 |
Schering Corporation |
Benzopyrido piperylidene compounds, compositions, methods of manufacture and methods of use
|
ES2040177B1
(es)
*
|
1992-03-06 |
1994-05-16 |
S A Tamarang |
Procedimiento para la sintesis de la 8-cloro-6, 11-dihidro-11, (1-etoxicarbonil-4-piperidiliden) -5h-benzo (5,6) ciclohepta-(1,2-b) piridina.
|
NZ251540A
(en)
*
|
1992-03-27 |
1996-09-25 |
Schering Corp |
Bridged bis-aryl carbinol derivatives, preparation and medicaments
|
DE69303605T2
(de)
*
|
1992-03-27 |
1997-01-23 |
Schering Corp |
Unverbrückte bis-aryl-carbinol-derivate, zusammensetzungen und ihre verwendung
|
ES2042421B1
(es)
*
|
1992-05-22 |
1994-08-01 |
Uriach & Cia Sa J |
Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
|
US5314697A
(en)
*
|
1992-10-23 |
1994-05-24 |
Schering Corporation |
Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
|
US6080428A
(en)
*
|
1993-09-20 |
2000-06-27 |
Bova; David J. |
Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
|
US6746691B2
(en)
|
1993-09-20 |
2004-06-08 |
Kos Pharmaceuticals, Inc. |
Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
|
US6676967B1
(en)
|
1993-09-20 |
2004-01-13 |
Kos Pharmaceuticals, Inc. |
Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
|
US6129930A
(en)
*
|
1993-09-20 |
2000-10-10 |
Bova; David J. |
Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
|
US6818229B1
(en)
|
1993-09-20 |
2004-11-16 |
Kos Pharmaceuticals, Inc. |
Intermediate release nicotinic acid compositions for treating hyperlipidemia
|
US5719148A
(en)
*
|
1993-10-15 |
1998-02-17 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
PT723538E
(pt)
*
|
1993-10-15 |
2002-05-31 |
Schering Corp |
Compostos triciclicos de carbamato uteis para a ainibicao da funcao da proteina g e para o tratamento de doencas proliferativas
|
US5721236A
(en)
*
|
1993-10-15 |
1998-02-24 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
US6365588B1
(en)
|
1993-10-15 |
2002-04-02 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
US6075025A
(en)
|
1993-10-15 |
2000-06-13 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
US5661152A
(en)
*
|
1993-10-15 |
1997-08-26 |
Schering Corporation |
Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
NZ275646A
(en)
*
|
1993-10-15 |
1998-02-26 |
Schering Corp |
Tricyclic sulphonamide derivatives and medicaments
|
US7211582B1
(en)
*
|
1994-12-30 |
2007-05-01 |
Sepracor Inc. |
Methods for treating urticaria using descarboethoxyloratadine
|
US5595997A
(en)
|
1994-12-30 |
1997-01-21 |
Sepracor Inc. |
Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
|
US7214683B1
(en)
|
1994-12-30 |
2007-05-08 |
Sepracor Inc. |
Compositions of descarboethoxyloratadine
|
US5684013A
(en)
*
|
1995-03-24 |
1997-11-04 |
Schering Corporation |
Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
US5700806A
(en)
*
|
1995-03-24 |
1997-12-23 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
US5712280A
(en)
*
|
1995-04-07 |
1998-01-27 |
Schering Corporation |
Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
US5801175A
(en)
*
|
1995-04-07 |
1998-09-01 |
Schering Corporation |
Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
IL117798A
(en)
*
|
1995-04-07 |
2001-11-25 |
Schering Plough Corp |
Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
|
US5891872A
(en)
*
|
1995-04-07 |
1999-04-06 |
Schering Corporation |
Tricyclic compounds
|
JP3779349B2
(ja)
*
|
1995-04-24 |
2006-05-24 |
興和株式会社 |
ピペリジン誘導体
|
JPH09152696A
(ja)
|
1995-11-30 |
1997-06-10 |
Fuji Photo Film Co Ltd |
ハロゲン化銀カラー写真感光材料
|
JP3383499B2
(ja)
|
1995-11-30 |
2003-03-04 |
富士写真フイルム株式会社 |
ハロゲン化銀カラー写真感光材料
|
US5874442A
(en)
*
|
1995-12-22 |
1999-02-23 |
Schering-Plough Corporation |
Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease
|
KR19990082367A
(ko)
*
|
1996-02-08 |
1999-11-25 |
폴락 돈나 엘. |
치료 방법 및 약제학적 조성물
|
JP3882224B2
(ja)
*
|
1996-05-31 |
2007-02-14 |
旭硝子株式会社 |
パロキセチンの製造方法
|
US5945429A
(en)
*
|
1996-09-13 |
1999-08-31 |
Schering Corporation |
Compounds useful for inhibition of farnesyl protein transferase
|
CZ84499A3
(cs)
*
|
1996-09-13 |
1999-08-11 |
Schering Corporation |
Substituované deriváty benzocykloheptapyridinu použitelné pro inhibici farnesylprotein transferasy
|
US5900421A
(en)
*
|
1997-02-11 |
1999-05-04 |
Sepracor Inc. |
Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
|
US5939426A
(en)
*
|
1997-02-28 |
1999-08-17 |
Sepracor Inc. |
Methods for treating urinary incontinence using descarboethoxyloratadine
|
SE509618C2
(sv)
|
1997-03-06 |
1999-02-15 |
Goeran Blomqvist |
Farmaceutisk komposition för behandling av s k restless legs
|
US5998620A
(en)
*
|
1997-03-25 |
1999-12-07 |
Schering Corporation |
Synthesis of intermediates useful in preparing tricyclic compounds
|
US6506767B1
(en)
|
1997-07-02 |
2003-01-14 |
Schering Corporation |
8-chloro-6,11-dihydro-11-(4-piperidylidine)-5H-benzo[5,6]cyclohepta[1-2-b] pyridine
|
US5869479A
(en)
*
|
1997-08-14 |
1999-02-09 |
Schering Corporation |
Treatment of upper airway allergic responses
|
JP2001519428A
(ja)
*
|
1997-10-10 |
2001-10-23 |
シェーリング コーポレイション |
エチル4−(8−クロロ−5,6−ジヒドロ−11H−ベンゾ[5,6]シクロヘプタ[1,2−b]ピリジン−11−イリデン)−1−ピペリデンカルボキシレート多形物
|
US6335347B1
(en)
*
|
1997-10-10 |
2002-01-01 |
Schering Corporation |
Ethyl 4-(8-chloro-5,6-dihydro-11 H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidene carboxylate polymorph
|
DK0968715T3
(da)
*
|
1998-06-30 |
2004-12-27 |
Pfizer Prod Inc |
Loratadin til anvendelse som et antiarytmikum
|
US6423721B1
(en)
|
1998-09-10 |
2002-07-23 |
Schering Corporation |
Methods and compositions for treating sinusitis, otitis media and other related disorders using antihistamines
|
US6372909B1
(en)
|
1998-11-20 |
2002-04-16 |
Schering Corporation |
Synthesis of intermediates useful in preparing tricyclic compounds
|
AR028138A1
(es)
|
1998-11-20 |
2003-04-30 |
Schering Corp |
Sintesis de intermediarios utiles para preparar compuestos triciclicos
|
US6271378B1
(en)
|
1998-12-18 |
2001-08-07 |
Schering Corporation |
Process for preparing tricyclic compounds having antihistaminic activity
|
CN1257166C
(zh)
*
|
1998-12-18 |
2006-05-24 |
先灵公司 |
制备具有抗组胺活性的三环化合物的方法
|
US6894059B1
(en)
|
1999-03-26 |
2005-05-17 |
Ucb S.A. |
Compounds and methods for treatment of asthma, allergy and inflammatory disorders
|
PE20001566A1
(es)
*
|
1999-03-26 |
2001-02-05 |
Ucb Sa |
Piperazinas 1,4-sustituidas, piperidinas 1,4-sustituidas y 4-alquilidenilpiperidinas 1-sustituidas
|
US6686502B1
(en)
|
1999-03-26 |
2004-02-03 |
Ucb S.A. |
Compounds and methods for treatment of asthma, allergy and inflammatory disorders
|
US6555139B2
(en)
|
1999-06-28 |
2003-04-29 |
Wockhardt Europe Limited |
Preparation of micron-size pharmaceutical particles by microfluidization
|
US6100274A
(en)
*
|
1999-07-07 |
2000-08-08 |
Schering Corporation |
8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions
|
BR0013720A
(pt)
|
1999-09-02 |
2002-07-23 |
Nostrum Pharmaceuticals Inc |
Formulação em pelota de liberação controlada
|
US6267986B1
(en)
|
1999-09-24 |
2001-07-31 |
Ranbaxy Laboratories Limited |
Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine
|
US6114346A
(en)
*
|
1999-10-22 |
2000-09-05 |
Schering Corporation |
Treating sleep disorders using desloratadine
|
WO2001045676A2
(en)
|
1999-12-20 |
2001-06-28 |
Schering Corporation |
Extended release oral dosage composition
|
SK287684B6
(sk)
*
|
1999-12-20 |
2011-06-06 |
Schering Corporation |
Pevná orálna farmaceutická dávková forma s predĺženým uvoľňovaním
|
US7405223B2
(en)
|
2000-02-03 |
2008-07-29 |
Schering Corporation |
Treating allergic and inflammatory conditions
|
CN1636982A
(zh)
|
2000-04-18 |
2005-07-13 |
先灵公司 |
用于制备三环化合物的中间产品的合成
|
WO2002036077A2
(en)
*
|
2000-11-06 |
2002-05-10 |
Andrx Pharmaceuticals, Inc. |
Once a day antihistamine and decongestant formulation
|
HU226998B1
(en)
|
2000-11-23 |
2010-04-28 |
Richter Gedeon Nyrt |
Desloratadine hemisulphate, process for the preparation thereof and pharmaceutical compositions containing the same
|
US6599913B1
(en)
*
|
2001-06-29 |
2003-07-29 |
Schering Corporation |
Treating allergic and inflammatory conditions
|
US6720002B2
(en)
|
2001-07-20 |
2004-04-13 |
R.P. Scherer Technologies, Inc. |
Antihistamine formulations for soft capsule dosage forms
|
US20030004179A1
(en)
*
|
2002-05-21 |
2003-01-02 |
Affrime Melton B |
Treating allergic and inflammatory conditions
|
US20040033257A1
(en)
*
|
2002-05-30 |
2004-02-19 |
Strides Inc. |
Pharmaceutical formulation in a drug delivery system and process for preparing the same
|
TW200400816A
(en)
*
|
2002-06-26 |
2004-01-16 |
Lilly Co Eli |
Tricyclic steroid hormone nuclear receptor modulators
|
US20040001885A1
(en)
*
|
2002-06-27 |
2004-01-01 |
Unchalee Kositprapa |
Rapidly disintegrating antihistamine formulation
|
US20040101563A1
(en)
*
|
2002-07-18 |
2004-05-27 |
Kundu Subhas C. |
Storage stable antihistaminic syrup formulations
|
US8092831B2
(en)
*
|
2002-11-08 |
2012-01-10 |
Andrx Pharmaceuticals, Llc |
Antihistamine and decongestant system
|
US6635654B1
(en)
|
2003-01-09 |
2003-10-21 |
Allergan, Inc. |
Ophthalmic compositions containing loratadine
|
WO2004108700A1
(en)
*
|
2003-03-12 |
2004-12-16 |
Teva Gyogyszergyar Reszvenytarsasag |
Processes for preparation of polymorphic forms of desloratadine
|
US20050026890A1
(en)
*
|
2003-07-31 |
2005-02-03 |
Robinson Cynthia B. |
Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
|
JP3881640B2
(ja)
*
|
2003-08-08 |
2007-02-14 |
塩野義製薬株式会社 |
ロラタジンを含むドライシロップ剤
|
US20060030550A1
(en)
*
|
2004-08-04 |
2006-02-09 |
Lithgow Theodore L |
Pharmaceutical formulations
|
US20060154948A1
(en)
*
|
2005-01-12 |
2006-07-13 |
Schering Corporation |
Treating allergic and inflammatory conditions
|
WO2006115770A2
(en)
*
|
2005-04-22 |
2006-11-02 |
Teva Pharmaceuticals Usa, Inc. |
Orally disintegrating pharmaceutical tablet formulations of olanzapine
|
AU2005333081B2
(en)
*
|
2005-06-17 |
2010-06-24 |
Aft Pharmaceuticals Limited |
Novel pharmaceutical composition and its use in a method for treatment of patients with upper respiratory mucosal congestion
|
US20080194823A1
(en)
*
|
2006-04-04 |
2008-08-14 |
Mayur Devjibhai Khunt |
Preparation of loratadine form i
|
TWI405567B
(zh)
*
|
2006-06-01 |
2013-08-21 |
Merck Sharp & Dohme |
持續釋放脫羥腎上腺素之醫藥組合物
|
BRPI0712532A2
(pt)
|
2006-06-01 |
2013-04-02 |
Schering Plough Healthcare Prod Inc |
formulaÇÕes e composiÇÕes farmacÊuticas de fenilefrina para absorÇço colânica
|
NZ573174A
(en)
|
2006-06-01 |
2012-01-12 |
Msd Consumer Care Inc |
Sustained release pharmaceutical dosage form containing phenylephrine
|
WO2007143382A2
(en)
*
|
2006-06-07 |
2007-12-13 |
Morton Grove Pharmaceuticals, Inc. |
Oral liquid loratadine formulations and methods
|
KR101561707B1
(ko)
|
2007-03-12 |
2015-10-19 |
넥타르 테라퓨틱스 |
올리고머―항히스타민제 컨주게이트
|
US20090082385A1
(en)
*
|
2007-09-26 |
2009-03-26 |
Protia, Llc |
Deuterium-enriched desloratidine
|
WO2010021681A2
(en)
*
|
2008-08-18 |
2010-02-25 |
Combinatorx (Singapore) Pte. Ltd. |
Compositions and methods for treatment of viral diseases
|
CA2764830A1
(en)
|
2009-06-16 |
2010-12-23 |
Schering Corporation |
Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof
|
US20110130711A1
(en)
*
|
2009-11-19 |
2011-06-02 |
Follica, Inc. |
Hair growth treatment
|
CA2690490C
(en)
|
2010-01-19 |
2012-06-26 |
Accucaps Industries Limited |
Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
|
EP2762141A4
(en)
|
2011-09-29 |
2015-03-25 |
Shionogi & Co |
THERAPEUTIC PHARMACEUTICAL PRODUCT AGAINST ALLERGIC RHINITIS COMPRISING A PGD2 ANTAGONIST AND A HISTAMINE ANTAGONIST
|
US10525057B2
(en)
|
2013-09-24 |
2020-01-07 |
Otsuka Pharmaceutical Co., Ltd. |
Method of providing aripiprazole to patients having impaired CYP2D6 or CYP3A4 enzyme function
|
CN106478595B
(zh)
*
|
2016-09-18 |
2019-05-21 |
西安交通大学 |
氯雷他定晶型及其制备方法和用途
|
CN110818684B
(zh)
*
|
2019-10-08 |
2023-04-07 |
深圳市南山区人民医院 |
一种抗金黄色葡萄球菌毒力和生物被膜形成的抑制剂Lo-SH及其用途
|
CN110845473B
(zh)
*
|
2019-10-08 |
2023-04-07 |
深圳市南山区人民医院 |
一种抗金黄色葡萄球菌毒力和生物被膜形成的抑制剂Lo-乙酸乙酯及其用途
|
CN110818685A
(zh)
*
|
2019-10-08 |
2020-02-21 |
深圳市南山区人民医院 |
一种抗金黄色葡萄球菌毒力和生物被膜形成的抑制剂Lo-异己基及其用途
|
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