SG50563A1 - New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents - Google Patents

New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents

Info

Publication number
SG50563A1
SG50563A1 SG1996005012A SG1996005012A SG50563A1 SG 50563 A1 SG50563 A1 SG 50563A1 SG 1996005012 A SG1996005012 A SG 1996005012A SG 1996005012 A SG1996005012 A SG 1996005012A SG 50563 A1 SG50563 A1 SG 50563A1
Authority
SG
Singapore
Prior art keywords
hepatitis
therapeutic
diagnostic agents
new sequences
present
Prior art date
Application number
SG1996005012A
Other languages
English (en)
Inventor
Geert Maertens
Lieven Stuyver
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Publication of SG50563A1 publication Critical patent/SG50563A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG1996005012A 1993-04-27 1994-04-27 New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents SG50563A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93401099 1993-04-27
EP93402019 1993-08-05

Publications (1)

Publication Number Publication Date
SG50563A1 true SG50563A1 (en) 1998-07-20

Family

ID=26134679

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996005012A SG50563A1 (en) 1993-04-27 1994-04-27 New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents

Country Status (15)

Country Link
US (3) US6762024B2 (fr)
EP (4) EP1004670B1 (fr)
JP (5) JPH07508423A (fr)
CN (1) CN1108030A (fr)
AT (4) ATE373093T1 (fr)
AU (1) AU688323B2 (fr)
BR (1) BR9405334A (fr)
CA (2) CA2139100C (fr)
DE (1) DE69435023T2 (fr)
ES (1) ES2294779T3 (fr)
FI (1) FI946066A (fr)
NO (1) NO944967L (fr)
NZ (1) NZ266148A (fr)
SG (1) SG50563A1 (fr)
WO (1) WO1994025601A2 (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3688290B2 (ja) * 1991-11-21 2005-08-24 コモン サーヴィシス エージェンシー Ｃ型肝炎ウイルス検査
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US7258977B1 (en) * 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
US7255997B1 (en) * 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
ATE373093T1 (de) 1993-04-27 2007-09-15 Innogenetics Nv Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika
US6881821B2 (en) 1993-05-05 2005-04-19 Common Services Agency Hepatitis-C virus type 4, 5, and 6
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US7129337B1 (en) * 1994-10-21 2006-10-31 Innogenetics N.V. Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents
US5851759A (en) * 1996-04-19 1998-12-22 Chiron Corporation Heteroduplex tracking assay (HTA) for genotyping HCV
EP2298900A1 (fr) * 1996-09-17 2011-03-23 Novartis Vaccines and Diagnostics, Inc. Compositions et procédés de traitement de maladies intracellulaires
AU751362B2 (en) 1998-04-17 2002-08-15 Innogenetics N.V. Improved immunodiagnostic assays using reducing agents
WO1999055385A2 (fr) * 1998-04-28 1999-11-04 Wolfgang Bergter Produits radioimmunopharmaceutiques pour le traitement de l'hepatite c
EP1113777B1 (fr) * 1998-06-09 2007-01-10 Andrea D. Branch Nouveaux peptides du virus de l'hepatite c et utilisations de ceux-ci
US7052830B1 (en) 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
BRPI0111731C1 (pt) 2000-06-15 2021-07-27 Chiron Corp suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
ATE375804T1 (de) * 2000-08-17 2007-11-15 Tripep Ab Ribavirin-enthaltende vakzine
US7196183B2 (en) * 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
MD2149G2 (ro) * 2001-11-23 2003-10-31 Институт Генетики И Физиологии Растений Академии Наук Молдовы Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C
DK1490383T3 (da) * 2002-03-11 2009-06-08 Lab 21 Ltd Fremgangsmåde og sammensætning til identifikation og karakterisering af hepatitis C
EP1523557A2 (fr) 2002-07-24 2005-04-20 Intercell AG Antigenes a phase de lecture alternante a partir de virus
EP2402026A3 (fr) 2002-09-13 2012-04-18 Intercell AG Procédé pour isoler des peptides du virus de l'hépatite C
WO2004084938A1 (fr) 2003-03-24 2004-10-07 Intercell Ag Vaccins ameliores
PL1648502T3 (pl) 2003-07-11 2011-05-31 Intercell Ag Szczepionki przeciwko HCV
US8124747B2 (en) 2003-08-29 2012-02-28 Innogenetics HCV clade and prototype sequences thereof
CN1977050B (zh) * 2004-01-07 2012-09-05 第三次浪潮技术公司 丙型肝炎病毒基因型的确定
US20060162667A1 (en) * 2005-01-26 2006-07-27 Papadoyianis Ernest D Aquatic habitat and ecological tank
CA2618429A1 (fr) * 2005-05-25 2007-03-22 Tripep Ab Gene de fusion ns3/4a non structurel de l'hepatite c
US20070072211A1 (en) 2005-06-30 2007-03-29 Roche Molecular Systems, Inc. Asymmetric PCR coupled with post-PCR characterization for the identification of nucleic acids
MD3300G2 (ro) * 2006-09-28 2007-11-30 Институт Генетики, Физиологии И Защиты Растений Академии Наук Молдовы Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C
WO2008046922A2 (fr) * 2006-10-20 2008-04-24 Innogenetics N.V. Méthode d'analyse des variations de séquence dans la zone génomique ns5b du vhc
WO2008046923A2 (fr) 2006-10-20 2008-04-24 Innogenetics N.V. Méthode d'analyse de variations de séquence dans une zone génomique ns3/4a du vhc
EP2463389A1 (fr) 2006-10-20 2012-06-13 Innogenetics N.V. Méthode d'analyse des variations de séquence dans la zone génomique NS5B du VHC
US20100227314A1 (en) * 2007-08-09 2010-09-09 Dmitry Alexandrovich Gryadunov Method of identification of genotype and subtype of hepatitis c virus on a biological microchip
EP2185195A2 (fr) * 2007-08-16 2010-05-19 Tripep Ab Plate-forme immunogène
CN101842498A (zh) * 2007-10-30 2010-09-22 英特芒尼公司 Hcv基因型分型和表型分型
WO2009130588A2 (fr) * 2008-04-22 2009-10-29 Tripep Ab Plateforme immunogène
WO2010112733A1 (fr) * 2009-03-30 2010-10-07 bioMérieux Support solide de détection du vhc
WO2013150450A1 (fr) * 2012-04-02 2013-10-10 Universidade Do Porto Fragments homologues du vhc, lignées cellulaires et applications associées
JP6859314B2 (ja) * 2015-03-27 2021-04-14 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドＯｒｔｈｏ−Ｃｌｉｎｉｃａｌ Ｄｉａｇｎｏｓｔｉｃｓ， Ｉｎｃ． Ｈｃｖ ｎｓ４ａ／改変されたｎｓ３ポリペプチド及びその使用
WO2018024562A1 (fr) * 2016-08-02 2018-02-08 Roche Diagnostics Gmbh Oligonucléotide auxiliaire pour améliorer l'efficacité de l'amplification et de la détection/quantification d'acides nucléiques

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049686C (zh) * 1987-11-18 2000-02-23 希龙股份有限公司 非ａ和非ｂ肝炎病毒的诊断及疫苗
US5350671A (en) 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
GB2236819B (en) * 1989-09-14 1993-07-14 Gen Motors France Dual master cylinder
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
WO1991004262A1 (fr) * 1989-09-15 1991-04-04 National Institute Of Health Of Japan Nouveaux isolats du virus de l'hepatite c
DK298190A (da) 1989-12-18 1991-06-19 Wellcome Found Viralt middel
EP0435229A1 (fr) * 1989-12-27 1991-07-03 Sanwa Kagaku Kenkyusho Co., Ltd. ADN d'un gène du virus de l'hépatite non-A non-B, son clonage et utilisation
WO1991014779A1 (fr) * 1990-03-28 1991-10-03 Mitsui Toatsu Chemicals, Incorporated Diagnostic du virus de l'hepatite
EP0461863A1 (fr) * 1990-06-12 1991-12-18 Immuno Japan Inc. Amorces oligonucléotidiques et leur utilisation pour la détection de non-A, non-B virus d'hépatite à haute fidélité
CA2045326A1 (fr) 1990-06-25 1991-12-26 Hiroto Okayama Particules du virus de l'hepatite non-a, non-b
DK0754704T3 (da) 1990-12-14 2000-04-03 Innogenetics Nv Syntetiske antigener til påvisning af antistoffer mod hepatitis c-virus
EP0510952A1 (fr) * 1991-04-26 1992-10-28 Immuno Japan Inc. Primaires d'oligonucleotides et leur application de détection à haut détail de non-A, non-B hepatitis
ATE252154T1 (de) 1991-05-08 2003-11-15 Chiron Corp Genomische hcv-sequenzen für diagnostik und therapie
RO117329B1 (ro) 1991-06-24 2002-01-30 Chiron Corp Emeryville Polipeptide care contin o secventa a virusului hepatitei c
EP0532167A3 (en) * 1991-08-09 1993-03-31 Immuno Japan Inc. Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
JPH06510191A (ja) * 1991-08-21 1994-11-17 アボツト・ラボラトリーズ Ｎｓ１に対する組換え抗原を利用したｃ型肝炎アッセイ
JPH06511149A (ja) 1991-09-13 1994-12-15 カイロン　コーポレイション 免疫反応性ｃ型肝炎ウイルスのポリペプチド組成物
JP3688290B2 (ja) * 1991-11-21 2005-08-24 コモン サーヴィシス エージェンシー Ｃ型肝炎ウイルス検査
AU681612B2 (en) * 1992-11-27 1997-09-04 N.V. Innogenetics S.A. Process for typing of hcv isolates
ATE373093T1 (de) 1993-04-27 2007-09-15 Innogenetics Nv Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika
GEP20012421B (en) 1993-05-10 2001-04-25 Chiron Corp Method for Typing Hepatitis C Virus and Reagents for Use Therein
JPH06319563A (ja) 1993-05-13 1994-11-22 Imuno Japan:Kk Ｃ型肝炎ウイルス遺伝子、オリゴヌクレオチド、並びにｃ型 肝炎ウイルス遺伝子型判定方法
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
JP2687852B2 (ja) * 1993-10-13 1997-12-08 日本電気株式会社 半導体メモリ装置

Also Published As

Publication number Publication date
CA2139100A1 (fr) 1994-11-10
JP2002233388A (ja) 2002-08-20
ATE552340T1 (de) 2012-04-15
US7195765B2 (en) 2007-03-27
CN1108030A (zh) 1995-09-06
AU688323B2 (en) 1998-03-12
EP0984067A2 (fr) 2000-03-08
NZ266148A (en) 1997-06-24
US6762024B2 (en) 2004-07-13
FI946066A0 (fi) 1994-12-23
CA2662090A1 (fr) 1994-11-10
JP2004041207A (ja) 2004-02-12
NO944967D0 (no) 1994-12-21
JPH07508423A (ja) 1995-09-21
ATE551423T1 (de) 2012-04-15
EP0651807A1 (fr) 1995-05-10
US7157226B1 (en) 2007-01-02
EP1004670B1 (fr) 2012-04-11
JP2004041206A (ja) 2004-02-12
CA2139100C (fr) 2009-06-23
WO1994025601A3 (fr) 1995-03-02
US20030008274A1 (en) 2003-01-09
EP0984067B1 (fr) 2012-04-04
AU6722294A (en) 1994-11-21
DE69435023T2 (de) 2008-09-11
EP0651807B1 (fr) 2007-09-12
DE69435023D1 (de) 2007-10-25
EP1004670A2 (fr) 2000-05-31
EP0984068A2 (fr) 2000-03-08
WO1994025601A2 (fr) 1994-11-10
JP2002233389A (ja) 2002-08-20
US20030032005A1 (en) 2003-02-13
FI946066A (fi) 1994-12-23
EP0984068B1 (fr) 2012-03-28
BR9405334A (pt) 1999-05-25
ATE373093T1 (de) 2007-09-15
ES2294779T3 (es) 2008-04-01
ATE553201T1 (de) 2012-04-15
NO944967L (no) 1994-12-21
EP1004670A3 (fr) 2000-09-20
EP0984067A3 (fr) 2000-09-27
EP0984068A3 (fr) 2000-09-20

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