SG49675A1 - New factor VIII coagulant polypeptides and monoclonal antibodies to them - Google Patents

New factor VIII coagulant polypeptides and monoclonal antibodies to them

Info

Publication number
SG49675A1
SG49675A1 SG1996003792A SG1996003792A SG49675A1 SG 49675 A1 SG49675 A1 SG 49675A1 SG 1996003792 A SG1996003792 A SG 1996003792A SG 1996003792 A SG1996003792 A SG 1996003792A SG 49675 A1 SG49675 A1 SG 49675A1
Authority
SG
Singapore
Prior art keywords
polypeptides
reacts
factor viii
those
react
Prior art date
Application number
SG1996003792A
Other languages
English (en)
Inventor
Theodore S Zimmerman
Carol A Fulcher
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27046849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG49675(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of SG49675A1 publication Critical patent/SG49675A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG1996003792A 1983-03-31 1984-04-02 New factor VIII coagulant polypeptides and monoclonal antibodies to them SG49675A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48110583A 1983-03-31 1983-03-31
US55650883A 1983-11-30 1983-11-30

Publications (1)

Publication Number Publication Date
SG49675A1 true SG49675A1 (en) 1998-06-15

Family

ID=27046849

Family Applications (2)

Application Number Title Priority Date Filing Date
SG1996003792A SG49675A1 (en) 1983-03-31 1984-04-02 New factor VIII coagulant polypeptides and monoclonal antibodies to them
SG1996008094A SG48229A1 (en) 1983-03-31 1984-04-02 Monoclonal antibodies to new factor viii coagulant polypeptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG1996008094A SG48229A1 (en) 1983-03-31 1984-04-02 Monoclonal antibodies to new factor viii coagulant polypeptides

Country Status (12)

Country Link
EP (3) EP0770396A3 (de)
JP (2) JPH0829089B2 (de)
AT (2) ATE155490T1 (de)
AU (1) AU572128B2 (de)
CA (1) CA1341506C (de)
DE (2) DE3486453T2 (de)
DK (2) DK172036B1 (de)
FI (1) FI841281A (de)
IE (2) IE80638B1 (de)
NO (1) NO167533C (de)
SG (2) SG49675A1 (de)
ZA (1) ZA842418B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
US5004804A (en) * 1984-01-12 1991-04-02 Nordisk Gentofte Method and composition for preparation of factor VIIIC
DE10399011I1 (de) * 1984-01-12 2003-10-23 Chiron Corp F}r Fakton-VIIIc kodierende DNA-Sequenzen und ver wandte DNA-Konstruktionen
US4716117A (en) * 1984-10-26 1987-12-29 Chiron Corporation Monoclonal antibodies to factor VIIIC
US7138505B1 (en) 1984-01-12 2006-11-21 Novartis Vaccines And Diagnostics, Inc. Factor VIII:C nucleic acid molecules
JPH0764879B2 (ja) * 1984-01-12 1995-07-12 チロン コ−ポレイシヨン フアクタ−ｖ▲ｉｉｉ▼ｃに対するモノクロ−ナル抗体
US5045455A (en) * 1984-01-12 1991-09-03 Chiron Corporation Factor VIII:C cDNA cloning and expression
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
IL74909A (en) * 1984-04-20 1992-01-15 Genentech Inc Preparation of functional human factor viii and dna sequences,expression vectors,transformed microorganisms and cell lines used therein
SE8501050D0 (sv) * 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
KR910006424B1 (ko) * 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
AU607927B2 (en) * 1986-06-24 1991-03-21 Nordisk Gentofte A/S A process for producing a coagulation active complex of factor viii fragments
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
EP0294910B1 (de) 1987-06-12 1996-09-11 Immuno Ag Proteine mit Faktor-VIII-Aktivität, Verfahren zu deren Herstellung unter Verwendung von genetisch modifizierten Zellen und diese enthaltende pharmazeutische Zusammensetzungen
IL88309A0 (en) * 1987-11-17 1989-06-30 Scripps Clinic Res Peptides for use in the purification of factor viii
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
WO1995003332A1 (en) * 1993-07-23 1995-02-02 Baxter International Inc. Activated human factor viii and method of preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
CZ307715B6 (cs) 1999-02-22 2019-03-06 University Of Connecticut Způsob lyofilizace vodné farmaceutické formulace faktoru VIII prosté albuminu
EP1418810A4 (de) 2001-08-03 2006-08-02 Us Gov Health & Human Serv Orale behandlung von hämophilie
TR201900207T4 (tr) 2008-11-07 2019-02-21 Baxalta GmbH Faktör VIII Formülasyonları
BRPI1105317A2 (pt) 2011-01-24 2013-04-30 Fundacco Hemoct De Ribeirco Preto produÇço estÁvel e em larga escala de fviii humano em linhagem celular humana sk-hep-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364937A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human T cell antigen and methods of preparing same
US4364936A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human monocyte antigen and methods of preparing same
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4397841A (en) * 1982-06-28 1983-08-09 Monsanto Company Production of blood coagulation factor VIII:C

Also Published As

Publication number Publication date
EP0123945B2 (de) 2000-04-19
DE3486423T2 (de) 1996-09-19
EP0123945B1 (de) 1996-03-13
CA1341506C (en) 2006-06-06
AU572128B2 (en) 1988-05-05
EP0123945A1 (de) 1984-11-07
DK174984A (da) 1984-10-01
DK172036B1 (da) 1997-09-22
EP0770396A3 (de) 1997-07-23
EP0561427B1 (de) 1997-07-16
SG48229A1 (en) 1998-04-17
ATE155490T1 (de) 1997-08-15
NO841277L (no) 1984-10-01
DE3486423T3 (de) 2001-02-08
EP0770396A2 (de) 1997-05-02
IE840788L (en) 1984-09-30
JPH0638790A (ja) 1994-02-15
EP0561427A1 (de) 1993-09-22
NO167533B (no) 1991-08-05
JPS59184130A (ja) 1984-10-19
NO167533C (no) 1991-11-13
DE3486453D1 (de) 1997-08-21
JPH0829089B2 (ja) 1996-03-27
DE3486453T2 (de) 1998-02-26
DK174984D0 (da) 1984-03-30
IE80858B1 (en) 1999-04-21
AU2627284A (en) 1984-10-04
IE960783L (en) 1984-09-30
DK50497A (da) 1997-05-02
IE80638B1 (en) 1998-10-21
ZA842418B (en) 1984-11-28
ATE135400T1 (de) 1996-03-15
DE3486423D1 (de) 1996-04-18
FI841281A (fi) 1984-10-01
FI841281A0 (fi) 1984-03-30

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