SG47201A1 - New crystal modification of cdch a process for its preparation and pharmaceutical formulations comprising this modification - Google Patents

New crystal modification of cdch a process for its preparation and pharmaceutical formulations comprising this modification

Info

Publication number
SG47201A1
SG47201A1 SG1996011612A SG1996011612A SG47201A1 SG 47201 A1 SG47201 A1 SG 47201A1 SG 1996011612 A SG1996011612 A SG 1996011612A SG 1996011612 A SG1996011612 A SG 1996011612A SG 47201 A1 SG47201 A1 SG 47201A1
Authority
SG
Singapore
Prior art keywords
modification
cdch
preparation
pharmaceutical formulations
new crystal
Prior art date
Application number
SG1996011612A
Other languages
English (en)
Inventor
Alfons Dr Grunenberg
Patrick Dr Bosche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG47201(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SG47201A1 publication Critical patent/SG47201A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG1996011612A 1995-12-12 1996-12-10 New crystal modification of cdch a process for its preparation and pharmaceutical formulations comprising this modification SG47201A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
SG47201A1 true SG47201A1 (en) 1998-03-20

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996011612A SG47201A1 (en) 1995-12-12 1996-12-10 New crystal modification of cdch a process for its preparation and pharmaceutical formulations comprising this modification

Country Status (42)

Country Link
US (1) US5849752A (en:Method)
EP (1) EP0780390B1 (en:Method)
JP (1) JP4104687B2 (en:Method)
KR (1) KR100525146B1 (en:Method)
CN (1) CN1061348C (en:Method)
AR (1) AR005009A1 (en:Method)
AT (1) ATE221531T1 (en:Method)
AU (1) AU708006B2 (en:Method)
BG (1) BG62258B1 (en:Method)
BR (1) BR9605968A (en:Method)
CA (1) CA2192418C (en:Method)
CO (1) CO4480105A1 (en:Method)
CU (1) CU22774A3 (en:Method)
CZ (1) CZ288657B6 (en:Method)
DE (2) DE19546249A1 (en:Method)
DK (1) DK0780390T3 (en:Method)
EE (1) EE03474B1 (en:Method)
ES (1) ES2179910T3 (en:Method)
HR (1) HRP960558B1 (en:Method)
HU (1) HU226521B1 (en:Method)
ID (1) ID22625A (en:Method)
IL (1) IL119795A (en:Method)
IN (1) IN185805B (en:Method)
MA (1) MA24342A1 (en:Method)
MY (1) MY117492A (en:Method)
NL (1) NL300109I1 (en:Method)
NO (1) NO306725B1 (en:Method)
NZ (1) NZ299905A (en:Method)
PL (1) PL184885B1 (en:Method)
PT (1) PT780390E (en:Method)
RO (1) RO119782B1 (en:Method)
RU (1) RU2162468C2 (en:Method)
SA (1) SA96170492B1 (en:Method)
SG (1) SG47201A1 (en:Method)
SI (1) SI0780390T1 (en:Method)
SK (1) SK282805B6 (en:Method)
SV (1) SV1996000109A (en:Method)
TR (1) TR199600970A2 (en:Method)
TW (1) TW411340B (en:Method)
UA (1) UA35638C2 (en:Method)
YU (1) YU49485B (en:Method)
ZA (1) ZA9610405B (en:Method)

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TR200000752T2 (tr) * 1997-09-25 2000-09-21 Bayer Aktiengesellschaft Etkin terkibin kontrollü salınımı için ilaç formülü.
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
HU229065B1 (en) 1998-11-10 2013-07-29 Bayer Ip Gmbh Pharmaceutical moxifloxacin compositions
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
EP1562942A1 (en) * 2002-10-31 2005-08-17 Ranbaxy Laboratories, Ltd. Amorphous moxifloxacin hydrochloride
ATE439840T1 (de) * 2003-04-09 2009-09-15 Reddys Lab Ltd Dr Kristalline form iii von wasserfreiem moxifloxacin-hydrochlorid und ein verfahren zu seiner herstellung
US20060264635A1 (en) * 2003-08-05 2006-11-23 Chava Satyanarayana Process for the preparation of moxifloxacin hydrochloride
EP1685130B1 (en) * 2003-11-20 2008-12-10 CHEMI S.p.A. Polymorphs of 1-cyclopropyl-7-([s,s] - 2,8-diazadicyclo [4.3.0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
EP2145890B1 (en) 2006-06-27 2012-08-01 Sandoz AG Crystallization of hydrohalides of pharmaceutical compounds
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
KR20150048920A (ko) 2006-11-13 2015-05-07 씨아이피엘에이 엘티디. 목시플록사신 염산염의 합성방법
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
ES2391132T3 (es) * 2008-10-09 2012-11-21 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Uso de disolventes orgánicos en la granulación húmeda de moxifloxacino
US20110212990A1 (en) * 2008-11-06 2011-09-01 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
ES2467105T5 (es) 2008-12-08 2017-12-05 Ratiopharm Gmbh Moxifloxacino compactado
NZ596492A (en) 2009-05-15 2013-08-30 Redx Pharma Ltd Redox drug derivatives
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
US9388178B2 (en) 2012-12-04 2016-07-12 Mankind Research Centre Process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
TWI641372B (zh) 2013-03-15 2018-11-21 美商梅琳塔有限責任公司 使用抗生素治療超重和肥胖患者感染的方法

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
DK164287A (da) * 1986-03-31 1987-10-01 Sankyo Co Quinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf og deres anvendelse
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
RO108347B1 (ro) * 1989-10-30 1994-04-28 Bellon Labor Sa Roger DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA
TW209865B (en:Method) 1992-01-10 1993-07-21 Bayer Ag
WO1993015070A1 (en) * 1992-01-31 1993-08-05 Chugai Seiyaku Kabushiki Kaisha Crystal of quinolonecarboxylic acid derivative hydrate
DE4234078A1 (de) 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
NO301165B1 (no) * 1992-12-25 1997-09-22 Daiichi Seiyaku Co Bicykliske aminderivater og antibakterielle midler inneholdende disse
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
DE69504392T2 (de) * 1994-04-07 1999-02-11 Pfizer Inc., New York, N.Y. Verwendung von Trovafloxacin oder dessen Derivaten zur Herstellung eines Arzneimittels zur Behandlung von H.Pylori Infektionen

Also Published As

Publication number Publication date
PT780390E (pt) 2002-11-29
EP0780390B1 (de) 2002-07-31
MA24342A1 (fr) 1998-07-01
IL119795A0 (en) 1997-03-18
NO306725B1 (no) 1999-12-13
NO965298D0 (no) 1996-12-11
CA2192418A1 (en) 1997-06-13
SV1996000109A (es) 1997-10-23
NZ299905A (en) 1998-09-24
IL119795A (en) 1998-12-27
SI0780390T1 (en) 2002-10-31
MY117492A (en) 2004-07-31
PL317415A1 (en) 1997-06-23
IN185805B (en:Method) 2001-05-05
HUP9603428A2 (en) 1997-08-28
US5849752A (en) 1998-12-15
EE03474B1 (et) 2001-08-15
NO965298L (no) 1997-06-13
CN1061348C (zh) 2001-01-31
DE19546249A1 (de) 1997-06-19
AR005009A1 (es) 1999-04-07
BG101043A (en) 1998-04-30
CN1160052A (zh) 1997-09-24
MX9606325A (es) 1997-10-31
ID22625A (id) 1999-12-02
CZ364696A3 (en) 1997-07-16
CA2192418C (en) 2001-06-12
UA35638C2 (uk) 2001-04-16
EP0780390A1 (de) 1997-06-25
ES2179910T3 (es) 2003-02-01
CU22774A3 (es) 2002-07-24
DK0780390T3 (da) 2002-11-11
HRP960558A2 (en) 1998-02-28
CO4480105A1 (es) 1997-07-09
JP4104687B2 (ja) 2008-06-18
PL184885B1 (pl) 2003-01-31
DE59609501D1 (de) 2002-09-05
TR199600970A2 (tr) 1997-06-21
RU2162468C2 (ru) 2001-01-27
KR100525146B1 (ko) 2006-01-27
AU7421696A (en) 1997-06-19
BG62258B1 (bg) 1999-06-30
JPH09169757A (ja) 1997-06-30
NL300109I1 (nl) 2003-02-03
SK159196A3 (en) 1997-10-08
ZA9610405B (en) 1997-06-23
HRP960558B1 (en) 2002-04-30
BR9605968A (pt) 1998-08-18
ATE221531T1 (de) 2002-08-15
EE9600201A (et) 1997-06-16
SK282805B6 (sk) 2002-12-03
HUP9603428A3 (en) 1997-10-28
TW411340B (en) 2000-11-11
YU65096A (sh) 1998-12-23
HU9603428D0 (en) 1997-01-28
AU708006B2 (en) 1999-07-29
KR970042550A (ko) 1997-07-24
HU226521B1 (en) 2009-03-30
RO119782B1 (ro) 2005-03-30
CZ288657B6 (cs) 2001-08-15
YU49485B (sh) 2006-08-17
SA96170492B1 (ar) 2006-05-23

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