SG43383A1 - N n-diethyl-8,8-dipropyl-2-azaspiro[4.5]decane-2- propanamine dimaleate - Google Patents

N n-diethyl-8,8-dipropyl-2-azaspiro[4.5]decane-2- propanamine dimaleate

Info

Publication number
SG43383A1
SG43383A1 SG1996010235A SG1996010235A SG43383A1 SG 43383 A1 SG43383 A1 SG 43383A1 SG 1996010235 A SG1996010235 A SG 1996010235A SG 1996010235 A SG1996010235 A SG 1996010235A SG 43383 A1 SG43383 A1 SG 43383A1
Authority
SG
Singapore
Prior art keywords
azaspiro
dipropyl
decane
diethyl
propanamine dimaleate
Prior art date
Application number
SG1996010235A
Other languages
English (en)
Inventor
Raymond E Dagger
Carolyn W Grady
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of SG43383A1 publication Critical patent/SG43383A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
SG1996010235A 1995-07-13 1996-07-08 N n-diethyl-8,8-dipropyl-2-azaspiro[4.5]decane-2- propanamine dimaleate SG43383A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US113995P 1995-07-13 1995-07-13
US1606596P 1996-04-23 1996-04-23

Publications (1)

Publication Number Publication Date
SG43383A1 true SG43383A1 (en) 1997-10-17

Family

ID=26668617

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996010235A SG43383A1 (en) 1995-07-13 1996-07-08 N n-diethyl-8,8-dipropyl-2-azaspiro[4.5]decane-2- propanamine dimaleate

Country Status (29)

Country Link
EP (1) EP0753512B1 (bg)
JP (1) JP3949750B2 (bg)
KR (1) KR100404832B1 (bg)
CN (1) CN1067378C (bg)
AR (1) AR003452A1 (bg)
AT (1) ATE164154T1 (bg)
AU (1) AU716256B2 (bg)
BG (1) BG62359B1 (bg)
CA (1) CA2181006C (bg)
CZ (1) CZ289617B6 (bg)
DE (1) DE69600189T2 (bg)
DK (1) DK0753512T3 (bg)
EA (1) EA000037B1 (bg)
ES (1) ES2113765T3 (bg)
HK (1) HK1010052A1 (bg)
HU (1) HU226691B1 (bg)
IL (1) IL118815A (bg)
MA (1) MA23936A1 (bg)
MX (1) MX9602767A (bg)
NO (1) NO306672B1 (bg)
NZ (1) NZ286951A (bg)
PL (1) PL191019B1 (bg)
RO (1) RO117376B1 (bg)
SG (1) SG43383A1 (bg)
SK (1) SK281254B6 (bg)
TR (1) TR199600579A2 (bg)
TW (1) TW419462B (bg)
UA (1) UA42749C2 (bg)
UY (1) UY24283A1 (bg)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE350362T1 (de) * 2000-08-08 2007-01-15 Daiichi Seiyaku Co Verfahren zur herstellung von bicyclischen verbindungen und deren zwischenstufen
MXPA05009708A (es) * 2003-03-10 2006-05-25 Callisto Pharmaceuticals Inc Metodo para el tratamiento de cancer con composiciones de azaspirina.
CN104119321B (zh) * 2013-04-28 2017-09-08 齐鲁制药有限公司 二氢吲哚酮衍生物的二马来酸盐及其多晶型物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3211397A1 (de) * 1982-03-27 1983-11-10 Hoechst Ag, 6230 Frankfurt Spiro (4.(3+n))-2-aza-3-carbonsaeure-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
US4430335A (en) * 1983-02-09 1984-02-07 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1-azaspiro[4,5]decanes and their analgesic compositions
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
PT100566B (pt) * 1991-06-07 1999-06-30 Smithkline Beecham Corp Azaspiranos imunomoduladores, composicoes farmaceuticas que os contem, sua preparacao e seu uso
GB9122735D0 (en) * 1991-10-25 1991-12-11 Smithkline Beecham Corp Methods
GB9217116D0 (en) * 1992-08-13 1992-09-23 Smithkline Beecham Corp Methods
US5506232A (en) * 1994-03-28 1996-04-09 Boehringer Mannheim Italia S.P.A. 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and its dimaleate salt

Also Published As

Publication number Publication date
CZ289617B6 (cs) 2002-03-13
NO962931L (no) 1997-01-14
SK88696A3 (en) 1997-06-04
CZ203696A3 (en) 1997-03-12
EA199600048A3 (ru) 1997-03-31
UY24283A1 (es) 2001-10-25
TR199600579A2 (tr) 1997-01-21
TW419462B (en) 2001-01-21
KR970069987A (ko) 1997-11-07
JP3949750B2 (ja) 2007-07-25
BG100710A (bg) 1997-03-31
NO962931D0 (no) 1996-07-12
EA000037B1 (ru) 1998-02-26
JPH09118618A (ja) 1997-05-06
DE69600189T2 (de) 1998-10-15
ATE164154T1 (de) 1998-04-15
CN1140710A (zh) 1997-01-22
HUP9601918A2 (en) 1997-09-29
RO117376B1 (ro) 2002-02-28
EP0753512A1 (en) 1997-01-15
CN1067378C (zh) 2001-06-20
DE69600189D1 (de) 1998-04-23
KR100404832B1 (ko) 2004-01-13
IL118815A (en) 2000-06-29
PL191019B1 (pl) 2006-03-31
CA2181006C (en) 2007-04-03
ES2113765T3 (es) 1998-05-01
NO306672B1 (no) 1999-12-06
UA42749C2 (uk) 2001-11-15
MX9602767A (es) 1998-01-31
CA2181006A1 (en) 1997-01-14
AR003452A1 (es) 1998-08-05
AU716256B2 (en) 2000-02-24
SK281254B6 (sk) 2001-01-18
AU5945596A (en) 1997-01-23
DK0753512T3 (da) 1998-10-19
BG62359B1 (bg) 1999-09-30
HU226691B1 (en) 2009-06-29
NZ286951A (en) 1998-02-26
EP0753512B1 (en) 1998-03-18
EA199600048A2 (ru) 1996-12-30
HK1010052A1 (en) 1999-06-11
HUP9601918A3 (en) 1998-01-28
MA23936A1 (fr) 1997-04-01
IL118815A0 (en) 1996-10-31
HU9601918D0 (en) 1996-09-30
PL315191A1 (en) 1997-01-20

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