SG165995A1 - Phenol derivatives and their use as rotamase inhibitors - Google Patents
Phenol derivatives and their use as rotamase inhibitorsInfo
- Publication number
- SG165995A1 SG165995A1 SG200702382-3A SG2007023823A SG165995A1 SG 165995 A1 SG165995 A1 SG 165995A1 SG 2007023823 A SG2007023823 A SG 2007023823A SG 165995 A1 SG165995 A1 SG 165995A1
- Authority
- SG
- Singapore
- Prior art keywords
- substituted
- alkyl
- straight
- poly
- mono
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/18—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20020020987 EP1402888A1 (en) | 2002-09-18 | 2002-09-18 | The use of substituted carbocyclic compounds as rotamases inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
SG165995A1 true SG165995A1 (en) | 2010-11-29 |
Family
ID=31970282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG200702382-3A SG165995A1 (en) | 2002-09-18 | 2003-09-18 | Phenol derivatives and their use as rotamase inhibitors |
Country Status (14)
Country | Link |
---|---|
US (2) | US20070054904A1 (xx) |
EP (3) | EP1402888A1 (xx) |
JP (2) | JP2005539072A (xx) |
KR (1) | KR20050053673A (xx) |
CN (1) | CN100546977C (xx) |
AU (1) | AU2003271619A1 (xx) |
BR (1) | BR0314544A (xx) |
CA (1) | CA2498662A1 (xx) |
MX (1) | MXPA05003084A (xx) |
PL (1) | PL374846A1 (xx) |
RU (2) | RU2005111256A (xx) |
SG (1) | SG165995A1 (xx) |
WO (1) | WO2004026815A2 (xx) |
ZA (1) | ZA200501913B (xx) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1594847A2 (en) * | 2003-02-12 | 2005-11-16 | Transtech Pharma, Inc. | Substituted azole derivatives as therapeutic agents |
WO2004089296A2 (en) | 2003-04-03 | 2004-10-21 | The Regents Of The University Of California | Improved inhibitors for the soluble epoxide hydrolase |
PT1701940E (pt) * | 2003-12-23 | 2008-07-30 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-benzil-amina como ssri |
CN1918131B (zh) * | 2004-02-05 | 2011-05-04 | 前体生物药物股份公司 | 谷氨酰胺酰基环化酶抑制剂 |
EP1765311A4 (en) | 2004-03-16 | 2009-04-29 | Univ California | REDUCTION OF NEPHROPATHY WITH INHIBITORS OF SOLUBLE EPOXY HYDROLASE AND EPOXYEICOSANOIDS |
MXPA06013118A (es) * | 2004-05-12 | 2007-02-28 | Schering Corp | Antagonistas de cxcr1 y cxcr2 de quimocina. |
US7550499B2 (en) | 2004-05-12 | 2009-06-23 | Bristol-Myers Squibb Company | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions |
AR052308A1 (es) * | 2004-07-16 | 2007-03-14 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto |
NZ554555A (en) * | 2004-10-20 | 2011-09-30 | Univ California | Cyclohexyl-urea derivatives as improved inhibitors for the soluble epoxide hydrolase |
JP2008527043A (ja) | 2005-01-19 | 2008-07-24 | ブリストル−マイヤーズ スクイブ カンパニー | 血栓塞栓障害治療用のp2y1受容体阻害剤としての2−フェノキシ−n−(1,3,4−チアジアゾール−2−イル)ピリジン−3−アミン誘導体および関連化合物 |
CA2605508A1 (en) * | 2005-05-12 | 2006-11-23 | Wisconsin Alumni Research Foundation | Blockade of pin1 prevents cytokine production by activated immune cells |
US7629473B2 (en) * | 2005-06-17 | 2009-12-08 | H. Lundbeck A/S | 2-(1H-indolylsulfanyl)-aryl amine derivatives |
AR054393A1 (es) * | 2005-06-17 | 2007-06-20 | Lundbeck & Co As H | Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos. |
US7714002B2 (en) | 2005-06-27 | 2010-05-11 | Bristol-Myers Squibb Company | Carbocycle and heterocycle antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions |
ATE502924T1 (de) | 2005-06-27 | 2011-04-15 | Bristol Myers Squibb Co | Lineare harnstoffmimetika-antagonisten des p2y1- rezeptors zur behandlung von thromboseleiden |
EP1899299B1 (en) | 2005-06-27 | 2010-10-20 | Bristol-Myers Squibb Company | C-linked cyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions |
US7728008B2 (en) | 2005-06-27 | 2010-06-01 | Bristol-Myers Squibb Company | N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions |
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2003
- 2003-09-18 CA CA002498662A patent/CA2498662A1/en not_active Abandoned
- 2003-09-18 KR KR1020057004693A patent/KR20050053673A/ko not_active Application Discontinuation
- 2003-09-18 US US10/528,139 patent/US20070054904A1/en not_active Abandoned
- 2003-09-18 AU AU2003271619A patent/AU2003271619A1/en not_active Abandoned
- 2003-09-18 BR BR0314544-1A patent/BR0314544A/pt not_active IP Right Cessation
- 2003-09-18 RU RU2005111256/04A patent/RU2005111256A/ru not_active Application Discontinuation
- 2003-09-18 CN CNB038252651A patent/CN100546977C/zh not_active Expired - Fee Related
- 2003-09-18 EP EP03753427A patent/EP1539683A2/en not_active Ceased
- 2003-09-18 WO PCT/EP2003/010406 patent/WO2004026815A2/en active Application Filing
- 2003-09-18 JP JP2004537125A patent/JP2005539072A/ja not_active Withdrawn
- 2003-09-18 MX MXPA05003084A patent/MXPA05003084A/es not_active Application Discontinuation
- 2003-09-18 SG SG200702382-3A patent/SG165995A1/en unknown
- 2003-09-18 EP EP09007837A patent/EP2100876A3/en not_active Withdrawn
- 2003-09-18 PL PL03374846A patent/PL374846A1/xx not_active Application Discontinuation
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2005
- 2005-03-07 ZA ZA2005/01913A patent/ZA200501913B/en unknown
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2009
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2010
- 2010-09-02 RU RU2010136779/04A patent/RU2010136779A/ru not_active Application Discontinuation
- 2010-09-29 JP JP2010219856A patent/JP2011037869A/ja active Pending
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Also Published As
Publication number | Publication date |
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CN100546977C (zh) | 2009-10-07 |
JP2011037869A (ja) | 2011-02-24 |
AU2003271619A1 (en) | 2004-04-08 |
US20070054904A1 (en) | 2007-03-08 |
ZA200501913B (en) | 2005-07-27 |
BR0314544A (pt) | 2005-08-16 |
RU2010136779A (ru) | 2012-03-10 |
KR20050053673A (ko) | 2005-06-08 |
JP2005539072A (ja) | 2005-12-22 |
US20110065760A1 (en) | 2011-03-17 |
PL374846A1 (en) | 2005-11-14 |
EP1539683A2 (en) | 2005-06-15 |
MXPA05003084A (es) | 2005-11-17 |
CA2498662A1 (en) | 2004-04-01 |
CN1701061A (zh) | 2005-11-23 |
WO2004026815A2 (en) | 2004-04-01 |
EP1402888A1 (en) | 2004-03-31 |
RU2005111256A (ru) | 2006-10-27 |
EP2100876A2 (en) | 2009-09-16 |
EP2100876A3 (en) | 2010-02-24 |
WO2004026815A3 (en) | 2004-12-02 |
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