SG161311A1 - Novel use of spiegelmers - Google Patents

Novel use of spiegelmers

Info

Publication number
SG161311A1
SG161311A1 SG201002837-1A SG2010028371A SG161311A1 SG 161311 A1 SG161311 A1 SG 161311A1 SG 2010028371 A SG2010028371 A SG 2010028371A SG 161311 A1 SG161311 A1 SG 161311A1
Authority
SG
Singapore
Prior art keywords
spiegelmers
novel use
relates
active agent
present
Prior art date
Application number
SG201002837-1A
Other languages
English (en)
Inventor
Florian Jarosch
Christian Maasch
Sven Klussmann
Axel Vater
Dirk Eulberg
Werner Purschke
Klaus Buchner
Original Assignee
Noxxon Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noxxon Pharma Ag filed Critical Noxxon Pharma Ag
Publication of SG161311A1 publication Critical patent/SG161311A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
SG201002837-1A 2005-05-04 2006-05-04 Novel use of spiegelmers SG161311A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005020874 2005-05-04

Publications (1)

Publication Number Publication Date
SG161311A1 true SG161311A1 (en) 2010-05-27

Family

ID=36928624

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201002837-1A SG161311A1 (en) 2005-05-04 2006-05-04 Novel use of spiegelmers

Country Status (11)

Country Link
US (2) US8497250B2 (fr)
EP (2) EP1877069A2 (fr)
JP (2) JP2008540363A (fr)
KR (2) KR101418367B1 (fr)
CN (2) CN104293780A (fr)
AU (1) AU2006243334A1 (fr)
BR (1) BRPI0610367A2 (fr)
CA (1) CA2607185A1 (fr)
MX (1) MX2007013760A (fr)
SG (1) SG161311A1 (fr)
WO (1) WO2006117217A2 (fr)

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WO2007150030A2 (fr) 2006-06-23 2007-12-27 Massachusetts Institute Of Technology Synthèse microfluidique de nanoparticules organiques
EP2134830A2 (fr) 2007-02-09 2009-12-23 Massachusetts Institute of Technology Bioréacteur oscillant pour la culture de cellules
WO2008124639A2 (fr) 2007-04-04 2008-10-16 Massachusetts Institute Of Technology Fractions de ciblage de poly (acide aminé)
ES2627292T3 (es) 2007-10-12 2017-07-27 Massachusetts Institute Of Technology Nanotecnología de vacunas
US8343498B2 (en) 2008-10-12 2013-01-01 Massachusetts Institute Of Technology Adjuvant incorporation in immunonanotherapeutics
US8277812B2 (en) 2008-10-12 2012-10-02 Massachusetts Institute Of Technology Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
US8591905B2 (en) 2008-10-12 2013-11-26 The Brigham And Women's Hospital, Inc. Nicotine immunonanotherapeutics
US8343497B2 (en) 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
AU2010254551B2 (en) 2009-05-27 2016-10-20 Selecta Biosciences, Inc. Immunomodulatory agent-polymeric compounds
EP2533798A2 (fr) * 2010-02-09 2012-12-19 Universität Bremen P19arf, hmga2 et mdm2 destinés à être utilisés dans le diagnostic et le traitement d'une croissance cellulaire aberrante
EP2561079A1 (fr) 2010-04-21 2013-02-27 Noxxon Pharma AG Acides nucléiques se liant à un lipide
CA2798323A1 (fr) 2010-05-26 2011-12-01 Selecta Biosciences, Inc. Selection de dose de nanovecteurs synthetiques avec adjuvant
CN102375064A (zh) * 2010-08-26 2012-03-14 杭州华得森生物技术有限公司 用酶联免疫法检测人体中hmga2含量的体外诊断试剂盒
DE102010056610A1 (de) * 2010-12-31 2012-07-05 Volker A. Erdmann Pharmazeutische Zusammensetzung enthaltend L-DNA
US20130028857A1 (en) 2011-07-29 2013-01-31 Selecta Biosciences, Inc. Synthetic nanocarriers comprising polymers comprising multiple immunomodulatory agents
CN103958682A (zh) * 2011-10-21 2014-07-30 诺松制药股份公司 结合胰高血糖素的核酸
EP2802659A1 (fr) * 2012-01-10 2014-11-19 Noxxon Pharma AG Acides nucléiques se liant spécifiquement à cgrp
CN112587658A (zh) 2012-07-18 2021-04-02 博笛生物科技有限公司 癌症的靶向免疫治疗
US9233119B2 (en) * 2012-09-27 2016-01-12 Miami University Use of HGMA-targeted phosphorothioate DNA aptamers to suppress carcinogenic activity and increase sensitivity to chemotherapy agents in human cancer cells
US10679730B2 (en) 2013-05-28 2020-06-09 The University Of Chicago Prognostic and predictive breast cancer signature
WO2014193964A2 (fr) * 2013-05-28 2014-12-04 Marsha Rosner Signature pronostique et prédictive du cancer du sein
CN105899537A (zh) 2014-01-10 2016-08-24 博笛生物科技（北京）有限公司 靶向表达egfr的肿瘤的化合物和组合物
CN112546231A (zh) 2014-07-09 2021-03-26 博笛生物科技有限公司 用于治疗癌症的联合治疗组合物和联合治疗方法
CA2954446A1 (fr) 2014-07-09 2016-01-14 Shanghai Birdie Biotech, Inc. Combinaisons anti-pd-l1 pour le traitement des tumeurs
CN105440135A (zh) 2014-09-01 2016-03-30 博笛生物科技有限公司 用于治疗肿瘤的抗-pd-l1结合物
KR101755617B1 (ko) 2014-07-23 2017-07-10 한국과학기술연구원 삼차원 자기조립 핵산 나노입자 구조를 갖는 약물전달체
CN107249678B (zh) * 2014-12-19 2021-02-19 凯敏工业公司 使用离子电渗法进行生物活性分子的眼内递送
CA2985818A1 (fr) 2015-05-31 2016-12-08 Curegenix Corporation Compositions de combinaison comprenant un antagoniste de porcupine et un antagoniste de l'axe pd-l/pd-1 aux fins d'immunotherapie
US10221249B2 (en) 2015-09-10 2019-03-05 Affigen, Llc Method of making patient specific anti-idiotype antibodies
DE17829597T1 (de) * 2016-11-30 2019-12-05 Noxxon Pharma Ag Verfahren zur polyalkoxylierung von nukleinsäuren zur rückgewinnung und wiederverwendung einer überschüssigen polyalkoxylierungsreagenz
WO2020055663A1 (fr) * 2018-09-11 2020-03-19 The Texas A&M University System Inhibiteurs de l-oligonucléotide du complexe répressif polycomb 2 (prc2)
CN112725438B (zh) * 2021-02-05 2023-08-22 深圳市宝安区妇幼保健院 子宫内膜息肉甲基化标志物组合、检测试剂盒及应用
CN114807183B (zh) * 2021-12-06 2023-06-02 西藏自治区农牧科学院农业研究所 一种青稞矢车菊素氧甲基转移酶基因的新用途

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Also Published As

Publication number Publication date
KR101418369B1 (ko) 2014-07-24
JP2008540363A (ja) 2008-11-20
BRPI0610367A2 (pt) 2010-06-15
CN104293780A (zh) 2015-01-21
CN101217967A (zh) 2008-07-09
WO2006117217A2 (fr) 2006-11-09
MX2007013760A (es) 2008-01-28
US20090192100A1 (en) 2009-07-30
WO2006117217A3 (fr) 2007-08-09
US20130337049A1 (en) 2013-12-19
KR101418367B1 (ko) 2014-07-25
CN101217967B (zh) 2014-09-10
EP2206501A2 (fr) 2010-07-14
KR20080009276A (ko) 2008-01-28
US9074214B2 (en) 2015-07-07
KR20140042941A (ko) 2014-04-07
AU2006243334A1 (en) 2006-11-09
JP2013224319A (ja) 2013-10-31
EP2206501A3 (fr) 2010-09-29
US8497250B2 (en) 2013-07-30
EP1877069A2 (fr) 2008-01-16
CA2607185A1 (fr) 2006-11-09
JP5766750B2 (ja) 2015-08-19

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