SG148027A1 - Methods for identifying combinations of entities as therapeutics - Google Patents

Methods for identifying combinations of entities as therapeutics

Info

Publication number
SG148027A1
SG148027A1 SG200502530-9A SG2005025309A SG148027A1 SG 148027 A1 SG148027 A1 SG 148027A1 SG 2005025309 A SG2005025309 A SG 2005025309A SG 148027 A1 SG148027 A1 SG 148027A1
Authority
SG
Singapore
Prior art keywords
compounds
whole cells
combinations
effect
contacting
Prior art date
Application number
SG200502530-9A
Other languages
English (en)
Inventor
Brent R Stockwell
Alexis Borisy
Michael A Foley
Original Assignee
Combinatorx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Combinatorx Inc filed Critical Combinatorx Inc
Publication of SG148027A1 publication Critical patent/SG148027A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
SG200502530-9A 2000-07-07 2001-07-05 Methods for identifying combinations of entities as therapeutics SG148027A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61183500A 2000-07-07 2000-07-07

Publications (1)

Publication Number Publication Date
SG148027A1 true SG148027A1 (en) 2008-12-31

Family

ID=24450586

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200502530-9A SG148027A1 (en) 2000-07-07 2001-07-05 Methods for identifying combinations of entities as therapeutics

Country Status (20)

Country Link
US (3) US20020019011A1 (fr)
EP (2) EP1586900A3 (fr)
JP (1) JP3790447B2 (fr)
KR (1) KR100470825B1 (fr)
CN (1) CN1452719A (fr)
AR (1) AR029581A1 (fr)
AT (1) ATE298424T1 (fr)
AU (1) AU2001271841A1 (fr)
BR (1) BR0102781A (fr)
CA (1) CA2352515C (fr)
DE (1) DE60111595T2 (fr)
DK (1) DK1170591T3 (fr)
ES (1) ES2243367T3 (fr)
IL (1) IL144049A (fr)
MX (1) MXPA01006914A (fr)
NZ (2) NZ524186A (fr)
PT (1) PT1170591E (fr)
SG (1) SG148027A1 (fr)
TW (1) TWI240074B (fr)
WO (1) WO2002004946A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1243327A1 (fr) * 2001-03-19 2002-09-25 BioChip Technologies GmbH Surface avec un motif de cellules et méthode pour sa production
TW573125B (en) * 2001-08-29 2004-01-21 Combinatorx Inc A screening system for identifying drug-drug interactions and methods of use thereof
WO2004080445A1 (fr) * 2003-03-12 2004-09-23 Molecular Engines Laboratories Sa Methodes et compositions pour le traitement du cancer
ES2343411T3 (es) 2003-03-26 2010-07-30 Synergy Biosystems Ltd. Procedimientos para identificar agentes biologicamente activos y combinaciones sinergicas.
JP2007526438A (ja) * 2003-06-06 2007-09-13 コンビナトルックス インコーポレイテッド 組成物の組み合わせの多次元評価システムおよび方法
JP4632400B2 (ja) 2003-12-16 2011-02-16 キヤノン株式会社 細胞培養用基板、その製造方法、それを用いた細胞スクリーニング法
WO2005059086A1 (fr) * 2003-12-16 2005-06-30 Canon Kabushiki Kaisha Feuille de transfert de substance biologiquement active, kit pour culture cellulaire forme d'une plaque de culture cellulaire et d'une feuille de transfert de substance biologiquement active, procede de production y relatif, et procede de criblage d'etats de culture cellulaire utilisant cette feuille
US20060040338A1 (en) * 2004-08-18 2006-02-23 Odyssey Thera, Inc. Pharmacological profiling of drugs with cell-based assays
WO2008105855A2 (fr) * 2006-11-13 2008-09-04 University Of Wyoming Appareil et procédé pour mesurer la fluorescence de grands organismes multicellulaires
US20090269772A1 (en) * 2008-04-29 2009-10-29 Andrea Califano Systems and methods for identifying combinations of compounds of therapeutic interest
CN104090094A (zh) * 2013-05-28 2014-10-08 长兴化学工业股份有限公司 生物医学装置
EP3374751B1 (fr) * 2015-11-13 2024-01-24 The United States of America, as represented by The Secretary, Department of Health and Human Services Moyen de fixative et procede pous ses utilisations
EP3510175A4 (fr) * 2016-09-08 2020-06-24 Curematch, Inc. Optimisation d'options thérapeutiques en médecine personnalisée
DE102020202529A1 (de) * 2020-02-27 2021-09-02 Robert Bosch Gesellschaft mit beschränkter Haftung Verfahren zur Identifikation einer Wirkstoffkombination

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
CA2058252A1 (fr) * 1991-03-18 1992-09-19 Linda R. Robertson Essai de selection de produit synergiste pour biocides
US5885782A (en) * 1994-09-13 1999-03-23 Nce Pharmaceuticals, Inc. Synthetic antibiotics
US5985356A (en) * 1994-10-18 1999-11-16 The Regents Of The University Of California Combinatorial synthesis of novel materials
US5756304A (en) * 1995-07-14 1998-05-26 Molecular Solutions Screening of microorganisms for bioremediation
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
US6030942A (en) * 1996-08-30 2000-02-29 The Trustees Of The University Of Pennsylvania Peptides peptide analogs peptidomimetics and other small molecules useful for inhibiting the activity of ribonucleotide reductase
US5985214A (en) * 1997-05-16 1999-11-16 Aurora Biosciences Corporation Systems and methods for rapidly identifying useful chemicals in liquid samples
ATE322477T1 (de) * 1997-05-16 2006-04-15 Woman & Infants Hospital 3-epi-vitamin d2 verbindungen und ihre anwendungen
US5992226A (en) * 1998-05-08 1999-11-30 The United States Of America As Represented By The Secretary Of The Navy Apparatus and method for measuring intermolecular interactions by atomic force microscopy
US6219674B1 (en) * 1999-11-24 2001-04-17 Classen Immunotherapies, Inc. System for creating and managing proprietary product data
US7266458B2 (en) * 2000-03-06 2007-09-04 Bioseek, Inc. BioMAP analysis

Also Published As

Publication number Publication date
NZ524186A (en) 2004-10-29
WO2002004946A2 (fr) 2002-01-17
EP1170591B1 (fr) 2005-06-22
PT1170591E (pt) 2005-11-30
EP1586900A2 (fr) 2005-10-19
US20020019010A1 (en) 2002-02-14
DE60111595T2 (de) 2006-05-18
EP1170591A2 (fr) 2002-01-09
DK1170591T3 (da) 2005-10-10
IL144049A0 (en) 2002-04-21
WO2002004946A3 (fr) 2003-01-23
DE60111595D1 (de) 2005-07-28
US20020019011A1 (en) 2002-02-14
CA2352515C (fr) 2007-06-19
BR0102781A (pt) 2002-03-12
IL144049A (en) 2006-12-10
MXPA01006914A (es) 2004-10-15
JP3790447B2 (ja) 2006-06-28
NZ512821A (en) 2003-05-30
KR20020065340A (ko) 2002-08-13
ATE298424T1 (de) 2005-07-15
EP1170591A3 (fr) 2002-09-18
AR029581A1 (es) 2003-07-02
CA2352515A1 (fr) 2002-01-07
AU2001271841A1 (en) 2002-01-21
ES2243367T3 (es) 2005-12-01
US20060177877A1 (en) 2006-08-10
TWI240074B (en) 2005-09-21
CN1452719A (zh) 2003-10-29
KR100470825B1 (ko) 2005-03-08
JP2002328124A (ja) 2002-11-15
EP1586900A3 (fr) 2005-12-14

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