ATE336591T1 - Nachweisverfahren für kurze sequenzvarianten - Google Patents

Nachweisverfahren für kurze sequenzvarianten

Info

Publication number
ATE336591T1
ATE336591T1 AT00970925T AT00970925T ATE336591T1 AT E336591 T1 ATE336591 T1 AT E336591T1 AT 00970925 T AT00970925 T AT 00970925T AT 00970925 T AT00970925 T AT 00970925T AT E336591 T1 ATE336591 T1 AT E336591T1
Authority
AT
Austria
Prior art keywords
detection methods
sequence variants
short sequence
gene
oligonucletide
Prior art date
Application number
AT00970925T
Other languages
English (en)
Inventor
Sanjay Tyagi
Fred R Kramer
David Alland
Original Assignee
New York Health Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Health Res Inst filed Critical New York Health Res Inst
Application granted granted Critical
Publication of ATE336591T1 publication Critical patent/ATE336591T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT00970925T 1999-10-22 2000-10-13 Nachweisverfahren für kurze sequenzvarianten ATE336591T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16109699P 1999-10-22 1999-10-22

Publications (1)

Publication Number Publication Date
ATE336591T1 true ATE336591T1 (de) 2006-09-15

Family

ID=22579803

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00970925T ATE336591T1 (de) 1999-10-22 2000-10-13 Nachweisverfahren für kurze sequenzvarianten

Country Status (8)

Country Link
US (2) US7662550B1 (de)
EP (1) EP1230387B1 (de)
JP (1) JP4919568B2 (de)
AT (1) ATE336591T1 (de)
AU (1) AU781945B2 (de)
CA (1) CA2387306C (de)
DE (1) DE60030145T2 (de)
WO (1) WO2001031062A1 (de)

Families Citing this family (24)

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US6037137A (en) 1997-02-20 2000-03-14 Oncoimmunin, Inc. Fluorogenic peptides for the detection of protease activity
US6893868B2 (en) 1997-02-20 2005-05-17 Onco Immunin, Inc. Homo-doubly labeled compositions for the detection of enzyme activity in biological samples
US7312302B2 (en) 1997-02-20 2007-12-25 Oncolmmunin, Inc. Compositions for the detection of enzyme activity in biological samples and methods of use thereof
US7019129B1 (en) * 2000-05-09 2006-03-28 Biosearch Technologies, Inc. Dark quenchers for donor-acceptor energy transfer
ATE420351T1 (de) * 2001-08-31 2009-01-15 Gen Probe Inc Sonden mit affinitätsverschiebung zur quantifizierung von analytenpolynukleotiden
CA2493613A1 (en) * 2002-07-26 2004-02-05 Becton, Dickinson And Company Method for analyzing readings of nucleic acid assays
WO2006029014A2 (en) * 2004-09-02 2006-03-16 The Regents Of The University Of Colorado rRNA OLIGONUCLEOTIDE PROBES FOR SPECIFIC DETECTION OF MYCOBACTERIA AND METHODS OF USE THEREOF
EP2927238B1 (de) 2004-10-18 2018-01-17 Brandeis University Verfahren zur LATE Amplifikation und Sequenzierung von Nukleinsäuren
JP2006217909A (ja) * 2005-01-11 2006-08-24 Fuji Photo Film Co Ltd 抗酸菌属細菌の検出方法およびそのキット
US7584947B2 (en) * 2005-05-20 2009-09-08 The Boeing Company Reconfigurable workpiece support fixture
MX2010010881A (es) 2008-04-01 2011-03-04 Biosearch Tech Inc Sondas oscuras apagadoras de fluoroforo de acido nucleico estabilizado.
JP5575239B2 (ja) 2009-07-21 2014-08-20 ジェン−プローブ・インコーポレーテッド 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物
ES2549777T3 (es) 2009-10-21 2015-11-02 Brandeis University Métodos para analizar secuencias de ácido nucleico monocatenario
EP2638178B1 (de) * 2010-11-10 2016-10-05 Brandeis University Verfahren und kits zum nachweis und zur identifikation von mykobakterien
JP2013092393A (ja) * 2011-10-24 2013-05-16 Sony Corp ケミカルセンサ、生体分子検出装置及び生体分子検出方法
CN103946691B (zh) 2011-11-30 2016-11-23 索尼公司 化学传感器、化学传感器模块、化学物质检测装置和化学物质检测方法
CN104271767B (zh) 2012-02-03 2017-08-25 加州理工学院 多路生化测定中信号的编码和解码
EP2820157B1 (de) 2012-03-02 2019-05-01 Winthrop-University Hospital Verfahren zur verwendung von sondenbasierter pcr-detektion zum messen der konzentration von dna aus zirkulierenden entmethylierten beta-zellen als massstab für beta-zell-verlust bei diabetes
US9791372B2 (en) 2012-08-03 2017-10-17 California Institute Of Technology Multiplexing and quantification in PCR with reduced hardware and requirements
CA2964265A1 (en) 2014-10-10 2016-04-14 Rutgers, The State University Of New Jersey Polymerase chain reaction primers and probes for mycobacterium tuberculosis
US20160289734A1 (en) 2015-04-03 2016-10-06 University Of Massachusetts Methods of using oligonucleotide-guided argonaute proteins
CN116083543A (zh) 2016-04-01 2023-05-09 克罗玛科德公司 用于工程化信号产生的竞争性探针
EP3472354A4 (de) 2016-06-17 2020-01-01 California Institute of Technology Nukleinsäurereaktionen sowie zugehörige verfahren und zusammensetzungen
CN107058589A (zh) * 2017-06-09 2017-08-18 苏州达麦迪生物医学科技有限公司 一种快速检测尿路感染细菌的分子信标探针、试剂盒及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2031659A1 (en) * 1990-01-26 1991-07-27 John B. Findlay Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
CA2252048C (en) * 1996-04-12 2008-03-11 The Public Health Research Institute Of The City Of New York, Inc. Detection probes, kits and assays
WO1999013113A1 (en) * 1997-09-12 1999-03-18 The Public Health Research Institute Of The City Of New York, Inc. Non-competitive co-amplification methods
US6355421B1 (en) * 1997-10-27 2002-03-12 Boston Probes, Inc. Methods, kits and compositions pertaining to PNA molecular beacons
DE69942444D1 (de) 1998-02-04 2010-07-15 Life Technologies Corp Bestimmung des genotyps eines amplifikationsproduktes an mehreren allelen stellen
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits

Also Published As

Publication number Publication date
US20100120048A1 (en) 2010-05-13
US7662550B1 (en) 2010-02-16
DE60030145D1 (de) 2006-09-28
DE60030145T2 (de) 2008-01-10
EP1230387A4 (de) 2003-03-05
AU781945B2 (en) 2005-06-23
US9260761B2 (en) 2016-02-16
EP1230387A1 (de) 2002-08-14
WO2001031062A1 (en) 2001-05-03
EP1230387B1 (de) 2006-08-16
JP4919568B2 (ja) 2012-04-18
JP2003518924A (ja) 2003-06-17
CA2387306A1 (en) 2001-05-03
CA2387306C (en) 2010-04-27
AU8024000A (en) 2001-05-08

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