ATE336591T1 - Nachweisverfahren für kurze sequenzvarianten - Google Patents

Nachweisverfahren für kurze sequenzvarianten

Info

Publication number
ATE336591T1
ATE336591T1 AT00970925T AT00970925T ATE336591T1 AT E336591 T1 ATE336591 T1 AT E336591T1 AT 00970925 T AT00970925 T AT 00970925T AT 00970925 T AT00970925 T AT 00970925T AT E336591 T1 ATE336591 T1 AT E336591T1
Authority
AT
Austria
Prior art keywords
detection methods
sequence variants
short sequence
gene
oligonucletide
Prior art date
Application number
AT00970925T
Other languages
English (en)
Inventor
Sanjay Tyagi
Fred R Kramer
David Alland
Original Assignee
New York Health Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Health Res Inst filed Critical New York Health Res Inst
Application granted granted Critical
Publication of ATE336591T1 publication Critical patent/ATE336591T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00970925T 1999-10-22 2000-10-13 Nachweisverfahren für kurze sequenzvarianten ATE336591T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16109699P 1999-10-22 1999-10-22

Publications (1)

Publication Number Publication Date
ATE336591T1 true ATE336591T1 (de) 2006-09-15

Family

ID=22579803

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00970925T ATE336591T1 (de) 1999-10-22 2000-10-13 Nachweisverfahren für kurze sequenzvarianten

Country Status (8)

Country Link
US (2) US7662550B1 (de)
EP (1) EP1230387B1 (de)
JP (1) JP4919568B2 (de)
AT (1) ATE336591T1 (de)
AU (1) AU781945B2 (de)
CA (1) CA2387306C (de)
DE (1) DE60030145T2 (de)
WO (1) WO2001031062A1 (de)

Families Citing this family (29)

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US6893868B2 (en) 1997-02-20 2005-05-17 Onco Immunin, Inc. Homo-doubly labeled compositions for the detection of enzyme activity in biological samples
US6037137A (en) 1997-02-20 2000-03-14 Oncoimmunin, Inc. Fluorogenic peptides for the detection of protease activity
US7312302B2 (en) 1997-02-20 2007-12-25 Oncolmmunin, Inc. Compositions for the detection of enzyme activity in biological samples and methods of use thereof
US7019129B1 (en) * 2000-05-09 2006-03-28 Biosearch Technologies, Inc. Dark quenchers for donor-acceptor energy transfer
EP1440311B1 (de) * 2001-08-31 2009-01-07 Gen-Probe Incorporated Sonden mit affinitätsverschiebung zur quantifizierung von analytenpolynukleotiden
JP2005534307A (ja) * 2002-07-26 2005-11-17 ベクトン・ディキンソン・アンド・カンパニー 核酸検定の読み取り値を解析する方法、および、その装置
WO2006029014A2 (en) * 2004-09-02 2006-03-16 The Regents Of The University Of Colorado rRNA OLIGONUCLEOTIDE PROBES FOR SPECIFIC DETECTION OF MYCOBACTERIA AND METHODS OF USE THEREOF
RU2460804C2 (ru) * 2004-10-18 2012-09-10 Брандейс Юнивесити Способ гомогенной детекции по меньшей мере одного продукта одноцепочечной амплификации
JP2006217909A (ja) * 2005-01-11 2006-08-24 Fuji Photo Film Co Ltd 抗酸菌属細菌の検出方法およびそのキット
US7584947B2 (en) * 2005-05-20 2009-09-08 The Boeing Company Reconfigurable workpiece support fixture
WO2009124150A2 (en) 2008-04-01 2009-10-08 Biosearch Technologies, Inc. Stabilized nucleic acid dark quencher-fluorophore probes
AU2010276236B2 (en) 2009-07-21 2014-03-20 Gen-Probe Incorporated Methods and compositions for quantitative detection of nucleic acid sequences over an extended dynamic range
ES2743959T3 (es) 2009-10-21 2020-02-21 Univ Brandeis Kits para analizar secuencias de ácido nucleico monocatenario
EP3135775B1 (de) * 2010-11-10 2018-06-27 Brandeis University Kit zur detektion und identifizierung von mykobakterien
JP2013092393A (ja) * 2011-10-24 2013-05-16 Sony Corp ケミカルセンサ、生体分子検出装置及び生体分子検出方法
KR102047569B1 (ko) * 2011-11-30 2019-11-21 소니 주식회사 케미컬 센서, 케미컬 센서 모듈, 화학물질 검출 장치 및 화학물질 검출 방법
CN114717296B (zh) 2012-02-03 2025-04-04 加州理工学院 多路生化测定中信号的编码和解码
WO2013131083A1 (en) 2012-03-02 2013-09-06 Winthrop-University Hospital METHOD FOR USING PROBE BASED PCR DETECTION TO MEASURE THE LEVELS OF CIRCULATING DEMETHYLATED β CELL DERIVED DNA AS A MEASURE OF β CELL LOSS IN DIABETES
EP3901243A1 (de) 2012-08-03 2021-10-27 California Institute of Technology Multiplexing und quantifizierung in pcr mit reduzierter hardware und reduzierten anforderungen
LT3957753T (lt) 2014-10-10 2025-01-10 Rutgers, The State University Of New Jersey Polimerazės grandininės reakcijos pradmenys ir zondai, skirti mycobacterium tuberculosis
US20160289734A1 (en) 2015-04-03 2016-10-06 University Of Massachusetts Methods of using oligonucleotide-guided argonaute proteins
WO2017173035A1 (en) 2016-04-01 2017-10-05 Chromacode Inc. Competitive probes for engineering signal generation
US10066263B2 (en) 2016-06-17 2018-09-04 California Institute Of Technology Nucleic acid reactions and related methods and compositions
CN107058589A (zh) * 2017-06-09 2017-08-18 苏州达麦迪生物医学科技有限公司 一种快速检测尿路感染细菌的分子信标探针、试剂盒及方法
US12454720B2 (en) 2018-04-17 2025-10-28 ChromaCode, Inc. Methods and systems for multiplex analysis
US12203129B2 (en) 2018-07-03 2025-01-21 ChromaCode, Inc. Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays
CN116287425A (zh) * 2021-12-21 2023-06-23 广东菲鹏生物有限公司 一种进行hpv检测或分型的探针及其引物探针组合物
CN116287107A (zh) * 2021-12-21 2023-06-23 广东菲鹏生物有限公司 一种核酸探针及其使用方法
CN118891381A (zh) * 2022-02-28 2024-11-01 新加坡国立大学 分析微生物组成物的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2031659A1 (en) * 1990-01-26 1991-07-27 John B. Findlay Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
AU713667B2 (en) * 1996-04-12 1999-12-09 Phri Properties, Inc. Detection probes, kits and assays
CA2303414C (en) * 1997-09-12 2008-05-20 Phri Properties, Inc. Non-competitive co-amplification methods
ATE478090T1 (de) * 1997-10-27 2010-09-15 Boston Probes Inc SICH AUF ßPNA MOLECULAR BEACONSß BEZIEHENDE VERFAHREN, TESTSÄTZE UND ZUSAMMENSETZUNGEN
CA2318880C (en) * 1998-02-04 2010-07-27 Applied Biosystems, Llc Determination of a genotype of an amplification product at multiple allelic sites
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits

Also Published As

Publication number Publication date
US20100120048A1 (en) 2010-05-13
JP2003518924A (ja) 2003-06-17
AU781945B2 (en) 2005-06-23
US9260761B2 (en) 2016-02-16
CA2387306C (en) 2010-04-27
JP4919568B2 (ja) 2012-04-18
EP1230387A1 (de) 2002-08-14
DE60030145T2 (de) 2008-01-10
EP1230387A4 (de) 2003-03-05
DE60030145D1 (de) 2006-09-28
WO2001031062A1 (en) 2001-05-03
AU8024000A (en) 2001-05-08
EP1230387B1 (de) 2006-08-16
CA2387306A1 (en) 2001-05-03
US7662550B1 (en) 2010-02-16

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