DE60030145D1 - Nachweisverfahren für kurze sequenzvarianten - Google Patents

Nachweisverfahren für kurze sequenzvarianten

Info

Publication number
DE60030145D1
DE60030145D1 DE60030145T DE60030145T DE60030145D1 DE 60030145 D1 DE60030145 D1 DE 60030145D1 DE 60030145 T DE60030145 T DE 60030145T DE 60030145 T DE60030145 T DE 60030145T DE 60030145 D1 DE60030145 D1 DE 60030145D1
Authority
DE
Germany
Prior art keywords
sequence variants
detection procedure
short sequence
gene
oligonucletide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60030145T
Other languages
English (en)
Other versions
DE60030145T2 (de
Inventor
Sanjay Tyagi
R Kramer
David Alland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phri Properties inc Newark N j Us
Original Assignee
Public Health Research Institute of City of New York Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Public Health Research Institute of City of New York Inc filed Critical Public Health Research Institute of City of New York Inc
Publication of DE60030145D1 publication Critical patent/DE60030145D1/de
Application granted granted Critical
Publication of DE60030145T2 publication Critical patent/DE60030145T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
DE60030145T 1999-10-22 2000-10-13 Nachweisverfahren für kurze sequenzvarianten Expired - Lifetime DE60030145T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US161096P 1996-07-23
US16109699P 1999-10-22 1999-10-22
PCT/US2000/028515 WO2001031062A1 (en) 1999-10-22 2000-10-13 Assays for short sequence variants

Publications (2)

Publication Number Publication Date
DE60030145D1 true DE60030145D1 (de) 2006-09-28
DE60030145T2 DE60030145T2 (de) 2008-01-10

Family

ID=22579803

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60030145T Expired - Lifetime DE60030145T2 (de) 1999-10-22 2000-10-13 Nachweisverfahren für kurze sequenzvarianten

Country Status (8)

Country Link
US (2) US7662550B1 (de)
EP (1) EP1230387B1 (de)
JP (1) JP4919568B2 (de)
AT (1) ATE336591T1 (de)
AU (1) AU781945B2 (de)
CA (1) CA2387306C (de)
DE (1) DE60030145T2 (de)
WO (1) WO2001031062A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7312302B2 (en) 1997-02-20 2007-12-25 Oncolmmunin, Inc. Compositions for the detection of enzyme activity in biological samples and methods of use thereof
US6037137A (en) 1997-02-20 2000-03-14 Oncoimmunin, Inc. Fluorogenic peptides for the detection of protease activity
US6893868B2 (en) 1997-02-20 2005-05-17 Onco Immunin, Inc. Homo-doubly labeled compositions for the detection of enzyme activity in biological samples
US7019129B1 (en) 2000-05-09 2006-03-28 Biosearch Technologies, Inc. Dark quenchers for donor-acceptor energy transfer
WO2003020952A2 (en) * 2001-08-31 2003-03-13 Gen-Probe Incorporated Affinity-shifted probes for quantifying analyte polynucleotides
CA2493613A1 (en) * 2002-07-26 2004-02-05 Becton, Dickinson And Company Method for analyzing readings of nucleic acid assays
WO2006029014A2 (en) * 2004-09-02 2006-03-16 The Regents Of The University Of Colorado rRNA OLIGONUCLEOTIDE PROBES FOR SPECIFIC DETECTION OF MYCOBACTERIA AND METHODS OF USE THEREOF
ES2359322T3 (es) 2004-10-18 2011-05-20 Brandeis University Procedimiento para la amplificación de ácidos nucleicos.
JP2006217909A (ja) * 2005-01-11 2006-08-24 Fuji Photo Film Co Ltd 抗酸菌属細菌の検出方法およびそのキット
US7584947B2 (en) * 2005-05-20 2009-09-08 The Boeing Company Reconfigurable workpiece support fixture
SI2757091T1 (en) 2008-04-01 2018-01-31 Biosearch Technologies, Inc. Stabilized nucleic acid black gas-fluorofor probe
EP2456887B1 (de) 2009-07-21 2015-11-25 Gen-Probe Incorporated Verfahren und zusammensetzungen für den quantitativen nachweis von nukleinsäuresequenzen in einem erweiterten dynamischen bereich
EP2980224B1 (de) 2009-10-21 2019-07-03 Brandeis University Kits zur analyse einzelstrangiger nukleinsäuresequenzen
WO2012064978A2 (en) * 2010-11-10 2012-05-18 Brandeis University Compositions, methods, and kits for detecting and identifying mycobacteria
JP2013092393A (ja) * 2011-10-24 2013-05-16 Sony Corp ケミカルセンサ、生体分子検出装置及び生体分子検出方法
WO2013080473A1 (ja) * 2011-11-30 2013-06-06 ソニー株式会社 ケミカルセンサ、ケミカルセンサモジュール、化学物質検出装置及び化学物質検出方法
BR112014019168B1 (pt) 2012-02-03 2021-10-05 California Institute Of Technology Método capaz de detectar de forma não degenerada presença ou ausência de analitos em um único volume de amostra e método de detecção da presença ou ausência de cada analito dentre uma pluralidade de analitos
US9127317B2 (en) 2012-03-02 2015-09-08 Winthrop-University Hospital Method for using probe based PCR detection to measure the levels of circulating demethylated β cell derived DNA as a measure of β cell loss in diabetes
CN108753932B (zh) 2012-08-03 2022-12-02 加州理工学院 Pcr中具有减少的硬件和要求的多重化和定量
RU2717655C2 (ru) 2014-10-10 2020-03-24 Рутгерс, Зе Стейт Юниверсити Оф Нью-Джерси Праймеры и зонды для полимеразной цепной реакции для обнаружения mycobacterium tuberculosis
US20160289734A1 (en) 2015-04-03 2016-10-06 University Of Massachusetts Methods of using oligonucleotide-guided argonaute proteins
CN116083543A (zh) 2016-04-01 2023-05-09 克罗玛科德公司 用于工程化信号产生的竞争性探针
CN109642252A (zh) 2016-06-17 2019-04-16 加州理工学院 核酸反应及相关方法和组合物
CN107058589A (zh) * 2017-06-09 2017-08-18 苏州达麦迪生物医学科技有限公司 一种快速检测尿路感染细菌的分子信标探针、试剂盒及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2031659A1 (en) * 1990-01-26 1991-07-27 John B. Findlay Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
AU713667B2 (en) * 1996-04-12 1999-12-09 Phri Properties, Inc. Detection probes, kits and assays
JP4306957B2 (ja) * 1997-09-12 2009-08-05 ピーエイチアールアイ プロパティーズ，インコーポレイテッド 非競合的共増幅法
EP1025120B1 (de) * 1997-10-27 2010-08-18 Boston Probes, Inc. Sich auf "pna molecular beacons" beziehende verfahren, testsätze und zusammensetzungen
EP1053348B1 (de) * 1998-02-04 2010-06-02 Life Technologies Corporation Bestimmung des genotyps eines amplifikationsproduktes an mehreren allelen stellen
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits

Also Published As

Publication number Publication date
ATE336591T1 (de) 2006-09-15
EP1230387B1 (de) 2006-08-16
EP1230387A1 (de) 2002-08-14
US20100120048A1 (en) 2010-05-13
US7662550B1 (en) 2010-02-16
AU781945B2 (en) 2005-06-23
AU8024000A (en) 2001-05-08
CA2387306A1 (en) 2001-05-03
JP4919568B2 (ja) 2012-04-18
CA2387306C (en) 2010-04-27
DE60030145T2 (de) 2008-01-10
WO2001031062A1 (en) 2001-05-03
US9260761B2 (en) 2016-02-16
EP1230387A4 (de) 2003-03-05
JP2003518924A (ja) 2003-06-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PHRI PROPERTIES,INC., NEWARK, N:J., US

8328 Change in the person/name/address of the agent

Representative=s name: MUELLER FOTTNER STEINECKE RECHTSANWAELTE PATENTANW