ATE322477T1 - 3-epi-vitamin d2 verbindungen und ihre anwendungen - Google Patents

3-epi-vitamin d2 verbindungen und ihre anwendungen

Info

Publication number
ATE322477T1
ATE322477T1 AT98921249T AT98921249T ATE322477T1 AT E322477 T1 ATE322477 T1 AT E322477T1 AT 98921249 T AT98921249 T AT 98921249T AT 98921249 T AT98921249 T AT 98921249T AT E322477 T1 ATE322477 T1 AT E322477T1
Authority
AT
Austria
Prior art keywords
vitamin
compounds
epi
beta
applications
Prior art date
Application number
AT98921249T
Other languages
English (en)
Inventor
Satayanarayana G Reddy
Original Assignee
Woman & Infants Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Woman & Infants Hospital filed Critical Woman & Infants Hospital
Application granted granted Critical
Publication of ATE322477T1 publication Critical patent/ATE322477T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5929,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98921249T 1997-05-16 1998-05-15 3-epi-vitamin d2 verbindungen und ihre anwendungen ATE322477T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4664197P 1997-05-16 1997-05-16

Publications (1)

Publication Number Publication Date
ATE322477T1 true ATE322477T1 (de) 2006-04-15

Family

ID=21944565

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98921249T ATE322477T1 (de) 1997-05-16 1998-05-15 3-epi-vitamin d2 verbindungen und ihre anwendungen

Country Status (8)

Country Link
US (1) US6017908A (de)
EP (1) EP0981514B1 (de)
JP (1) JP2002506429A (de)
AT (1) ATE322477T1 (de)
AU (1) AU744471B2 (de)
CA (1) CA2288710A1 (de)
DE (1) DE69834109T2 (de)
WO (1) WO1998051664A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1178960T3 (da) * 1999-04-23 2004-03-15 Leo Pharma As Vitamin D analoger og deres farmaceutiske anvendelse
EP1178808B2 (de) * 1999-04-23 2019-06-12 Leo Pharma A/S Nicht-wässrige pharmazeutische zusammensetzung zur anwendung auf der haut für die behandlung von psoriasis enthaltend ein vitamin d, ein corticosteroid und eine lösungsmittelkomponente
EP1233942A2 (de) * 1999-12-02 2002-08-28 The Penn State Research Foundation Behandlung von entzündlichen darmerkrankungen mit vitamin d-verbindungen
US6358939B1 (en) * 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US20020137731A1 (en) 2000-05-30 2002-09-26 Gewirtz David A. Combination of radiation and vitamin D3 analogs for the treatment of cancer
US20020019011A1 (en) * 2000-07-07 2002-02-14 Stockwell Brent R. Methods for identifying combinations of entities as therapeutics
AU2003291810A1 (en) * 2002-11-18 2004-06-15 Teva Pharmaceutical Industries Ltd. A crystallization method for purification of calcipotriene
WO2004098522A2 (en) * 2003-04-30 2004-11-18 Bioxell S.P.A. Gemini vitamin d3 compounds and methods of use thereof
US20040253642A1 (en) * 2003-06-06 2004-12-16 Grant Zimmermann System and method for multidimensional evaluation of combinations of compositions
US20050192255A1 (en) * 2003-07-30 2005-09-01 Jin Tian Use of Vitamin Ds or Vitamin D analogs to treat cardiovascular disease
US20080039434A1 (en) * 2004-03-01 2008-02-14 Bioxell S. P.A. Treatment of Interstitial Cystitis with Vitamin D Compounds
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
KR20090039833A (ko) * 2006-08-29 2009-04-22 테바 파마슈티컬 인더스트리즈 리미티드 비타민 d 및 코르티코스테로이드를 포함하는 약학 조성물
SG173119A1 (en) * 2009-01-27 2011-08-29 Berg Biosystems Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
BR112012003372A2 (pt) 2009-08-14 2019-09-24 Berg Biosystems Llc vitamina d3 e análogos da mesma para o tratamento de alopecia.
EP3003497B1 (de) 2013-05-29 2024-02-14 BPGbio, Inc. Verhinderung oder verringerung von chemotherapieinduzierter alopezie mit vitamin d
DE102013215580A1 (de) * 2013-08-07 2015-02-12 Orgentec Diagnostika Gmbh 25-OH Vitamin D Derivate zur Bestimmung von Vitamin D Metaboliten

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038272A (en) * 1975-10-20 1977-07-26 Hoffmann-La Roche Inc. Stereospecific syntheses of 24r,25- and 24s,25-dihydroxycholesterol and alkanoyl derivatives thereof
US4021423A (en) * 1976-03-08 1977-05-03 Hoffmann-La Roche Inc. Syntheses of 24R,25- and 24S,25-dihydroxycholecalciferol
US4595776A (en) * 1983-03-21 1986-06-17 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
GB2139627B (en) * 1983-05-09 1987-02-04 Wisconsin Alumni Res Found 1 25-dihydroxylated vitamin d2 compounds and intermediates in the preparation thereof
JPS6144860A (ja) * 1984-08-10 1986-03-04 Taisho Pharmaceut Co Ltd 1α.25−ジヒドロキシ−26.27−ジメチルビタミンD↓3
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
US5104864A (en) * 1988-08-02 1992-04-14 Bone Care International, Inc. Method for treating and preventing loss of bone mass
US5547947A (en) * 1993-03-11 1996-08-20 Hoffmann-La Roche Inc. Methods of treatment
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
ZA95906B (en) * 1994-02-07 1996-08-06 Res Developments Foundation Non-viral vector
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger

Also Published As

Publication number Publication date
AU744471B2 (en) 2002-02-21
CA2288710A1 (en) 1998-11-19
EP0981514B1 (de) 2006-04-05
AU7390398A (en) 1998-12-08
DE69834109T2 (de) 2007-04-19
US6017908A (en) 2000-01-25
DE69834109D1 (de) 2006-05-18
WO1998051664A1 (en) 1998-11-19
JP2002506429A (ja) 2002-02-26
EP0981514A1 (de) 2000-03-01

Similar Documents

Publication Publication Date Title
ATE322477T1 (de) 3-epi-vitamin d2 verbindungen und ihre anwendungen
FI952797A (fi) D-vitamiinianalogin uusi kiteinen muoto
HUP0001232A2 (hu) Béta-amiloid peptid kibocsátást és/vagy szintézist gátló cikloalkil-, laktám-, laktonszármazékok, és ezek tio-analógjai, valamint e vegyületeket tartalmazó gyógyászati készítmények
HUP0100270A2 (hu) Eljárások és vegyületek béta-amiloid peptid kibocsátás és/vagy szintézisgátló peptidek, ezeket tartalmazó gyógyászati készítmények és alkalmazásuk
IL120266A (en) Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
MY116845A (en) New 19-nor-pregnene derivatives
WO1998051663A3 (en) 3-epi compounds of vitamin d3 and uses thereof
AU5715294A (en) Use of 2-amino-6-A-propylamino-4,5,6, 7-tetrahydrobenzothiazole (pramipexol) as an anti-depressantdrug
ES2192031T3 (es) Nuevas amidas aromaticas, su procedimiento de preparacion y su aplicacion como medicamentos.
RS50229B (sr) Analozi vitamina d3
GB9725750D0 (en) Compound
GB9725749D0 (en) Compound
PT100961A (pt) Oximas de azabiciclo-arilacetileno e -arilenino como agentes colinergicos e composicoes farmaceuticas que as contem
BG103789A (en) Fungicidal compositions
DK1101497T3 (da) Stabiliserende olieagtige præparationer af tobicillin (beta-lactam antibiotikum)
BR0011261A (pt) Composição oral compreendendo perlita, e, uso de perlita
MY141507A (en) Slider block radial compliance mechanism with integral deflection bearing
FI951588A (fi) Öljykoostumuksia
ES2103104T3 (es) Nuevos compuestos di- y poliaminicos utiles en la preparacion de poliuretanos.
BG103271A (en) Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means
DE69431662D1 (de) Stabilisierte tablettenformulierung
DK0904272T3 (da) Dihydrobenzofuran og beslægtede forbindelser, der er nyttige som antiinflammatoriske midler
ES2046923A1 (es) Procedimiento para la estabilizacion de elastomeros.
ATE204286T1 (de) Modifizierte alpha-d-glcp-(1,2)-alpha-d-glcp-(1, 3)-alpha-d-glcp-analoge
NO944124L (no) 17 yre

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties