DK1101497T3 - Stabiliserende olieagtige præparationer af tobicillin (beta-lactam antibiotikum) - Google Patents

Stabiliserende olieagtige præparationer af tobicillin (beta-lactam antibiotikum)

Info

Publication number
DK1101497T3
DK1101497T3 DK99925357T DK99925357T DK1101497T3 DK 1101497 T3 DK1101497 T3 DK 1101497T3 DK 99925357 T DK99925357 T DK 99925357T DK 99925357 T DK99925357 T DK 99925357T DK 1101497 T3 DK1101497 T3 DK 1101497T3
Authority
DK
Denmark
Prior art keywords
beta
tobicillin
lactam antibiotic
oily preparations
stabilizing
Prior art date
Application number
DK99925357T
Other languages
English (en)
Inventor
Hatsuo Shibatani
Tomoyasu Nakamura
Original Assignee
Schering Plough Animal Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Animal Health filed Critical Schering Plough Animal Health
Application granted granted Critical
Publication of DK1101497T3 publication Critical patent/DK1101497T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
DK99925357T 1998-08-04 1999-06-16 Stabiliserende olieagtige præparationer af tobicillin (beta-lactam antibiotikum) DK1101497T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22016198 1998-08-04
PCT/JP1999/003233 WO2000007628A1 (fr) 1998-08-04 1999-06-16 Preparations stabilisees de beta-lactamine

Publications (1)

Publication Number Publication Date
DK1101497T3 true DK1101497T3 (da) 2008-03-31

Family

ID=16746851

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99925357T DK1101497T3 (da) 1998-08-04 1999-06-16 Stabiliserende olieagtige præparationer af tobicillin (beta-lactam antibiotikum)

Country Status (14)

Country Link
US (1) US6514962B1 (da)
EP (1) EP1101497B1 (da)
JP (1) JP3531648B2 (da)
KR (1) KR100412231B1 (da)
CN (1) CN1149102C (da)
AT (1) ATE386546T1 (da)
CA (1) CA2339147C (da)
DE (1) DE69938184T2 (da)
DK (1) DK1101497T3 (da)
ES (1) ES2297925T3 (da)
HK (1) HK1041217A1 (da)
PT (1) PT1101497E (da)
TW (1) TW550081B (da)
WO (1) WO2000007628A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010635A1 (es) 1999-10-08 2001-08-15 Smithkline Beecham Corp Inhibidores de fab i utiles para el tratamiento de infecciones bacterianas
ES2320984T3 (es) * 2001-04-06 2009-06-01 Affinium Pharmaceuticals, Inc. Inhibidores de fab i.
ES2518316T3 (es) 2002-12-06 2014-11-05 Debiopharm International Sa Compuestos heterocíclicos, métodos de fabricación de los mismos y su uso en terapia
CA2519429C (en) * 2003-03-17 2013-08-06 Affinium Pharmaceuticals, Inc. Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
ES2515101T3 (es) 2004-06-04 2014-10-29 Debiopharm International Sa Derivados de acrilamida como agentes antibióticos
KR20080075027A (ko) * 2005-12-05 2008-08-13 아피늄 파마슈티컬스, 인크. Fabi 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물
EP2054422B1 (en) 2006-07-20 2017-06-14 Debiopharm International SA Acrylamide derivatives as fab i inhibitors
US8263613B2 (en) * 2007-02-16 2012-09-11 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab I inhibitors
NZ702695A (en) 2012-06-19 2015-10-30 Debiopharm Int Sa Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
US10751351B2 (en) 2016-02-26 2020-08-25 Debiopharm International S.A. Medicament for treatment of diabetic foot infections
BR112020000196A2 (pt) 2017-07-07 2020-07-07 Epicentrx, Inc. composições para administração parenteral de agentes terapêuticos

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59176209A (ja) * 1983-03-28 1984-10-05 Sankyo Co Ltd β−ラクタム環を有する化合物の直腸投与用組成物
SE8405611D0 (sv) 1984-11-09 1984-11-09 Astra Laekemedel Ab Process for stabilization of bacampicillin hydrochloride
US4731362A (en) 1985-08-05 1988-03-15 Shionogi & Co., Ltd. Alkylcarbamoyloxymethylcephem compounds
DK8603837A (da) 1985-08-13 1987-02-14
US5063074A (en) * 1990-01-30 1991-11-05 Rich Products Corporation Low fat low cholesterol milk products
JP3233434B2 (ja) 1992-04-01 2001-11-26 塩野義製薬株式会社 カルバペネム誘導体
FR2698560B1 (fr) * 1992-11-30 1995-02-03 Virbac Laboratoires Principes actifs pulvérulents stabilisés, compositions les contenant, leur procédé d'obtention et leurs applications.
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems
JPH06298769A (ja) 1993-04-13 1994-10-25 Fujisawa Pharmaceut Co Ltd アンピシリンフェニルエステルおよびその塩

Also Published As

Publication number Publication date
EP1101497A4 (en) 2002-03-06
KR20010071964A (ko) 2001-07-31
CN1322140A (zh) 2001-11-14
JP3531648B2 (ja) 2004-05-31
DE69938184D1 (de) 2008-04-03
EP1101497B1 (en) 2008-02-20
WO2000007628A1 (fr) 2000-02-17
CA2339147A1 (en) 2000-02-17
TW550081B (en) 2003-09-01
ES2297925T3 (es) 2008-05-01
DE69938184T2 (de) 2009-03-26
CN1149102C (zh) 2004-05-12
CA2339147C (en) 2009-04-21
PT1101497E (pt) 2008-04-23
ATE386546T1 (de) 2008-03-15
US6514962B1 (en) 2003-02-04
HK1041217A1 (zh) 2002-07-05
KR100412231B1 (ko) 2003-12-24
EP1101497A1 (en) 2001-05-23

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