GB2139627B - 1 25-dihydroxylated vitamin d2 compounds and intermediates in the preparation thereof - Google Patents
1 25-dihydroxylated vitamin d2 compounds and intermediates in the preparation thereofInfo
- Publication number
- GB2139627B GB2139627B GB08411794A GB8411794A GB2139627B GB 2139627 B GB2139627 B GB 2139627B GB 08411794 A GB08411794 A GB 08411794A GB 8411794 A GB8411794 A GB 8411794A GB 2139627 B GB2139627 B GB 2139627B
- Authority
- GB
- United Kingdom
- Prior art keywords
- intermediates
- compounds
- preparation
- dihydroxylated vitamin
- dihydroxylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49286383A | 1983-05-09 | 1983-05-09 |
Publications (3)
Publication Number | Publication Date |
---|---|
GB8411794D0 GB8411794D0 (en) | 1984-06-13 |
GB2139627A GB2139627A (en) | 1984-11-14 |
GB2139627B true GB2139627B (en) | 1987-02-04 |
Family
ID=23957917
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08411794A Expired GB2139627B (en) | 1983-05-09 | 1984-05-09 | 1 25-dihydroxylated vitamin d2 compounds and intermediates in the preparation thereof |
GB08507475A Expired GB2158443B (en) | 1983-05-09 | 1985-03-22 | 1a,25-dihydroxylated vitamin d2 intermediates |
GB08507474A Expired GB2158442B (en) | 1983-05-09 | 1985-03-22 | Cyclovitamin d compounds |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08507475A Expired GB2158443B (en) | 1983-05-09 | 1985-03-22 | 1a,25-dihydroxylated vitamin d2 intermediates |
GB08507474A Expired GB2158442B (en) | 1983-05-09 | 1985-03-22 | Cyclovitamin d compounds |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS60501261A (en) |
BE (1) | BE899612A (en) |
FR (1) | FR2545824B1 (en) |
GB (3) | GB2139627B (en) |
IE (1) | IE58277B1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4769181A (en) * | 1983-11-07 | 1988-09-06 | Wisconsin Alumni Research Foundation | 1,25-dihydroxyvitamin D2 compounds |
JP2608322B2 (en) * | 1988-04-11 | 1997-05-07 | 日清製粉株式会社 | Method for producing 1α, 25-dihydroxyvitamin D |
US5260290A (en) * | 1990-02-14 | 1993-11-09 | Wisconsin Alumni Research Foundation | Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives |
US5030772A (en) * | 1990-02-14 | 1991-07-09 | Deluca Hector F | Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives |
US5571802A (en) * | 1993-02-19 | 1996-11-05 | Wisconsin Alumni Research Foundation | Method of treating post menopausal osteoporosis with hexafluro-vitamin D |
ATE322477T1 (en) * | 1997-05-16 | 2006-04-15 | Woman & Infants Hospital | 3-EPI-VITAMIN D2 COMPOUNDS AND THEIR APPLICATIONS |
WO1998051678A1 (en) | 1997-05-16 | 1998-11-19 | Women & Infants Hospital | CYCLIC ETHER VITAMIN D3 COMPOUNDS, 1α (OH) 3-EPI-VITAMIN D3 COMPOUNDS AND USES THEREOF |
WO2002030430A1 (en) * | 2000-10-06 | 2002-04-18 | Abbott Laboratories | Use of vitamin d2 compounds for alopecia |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL188286C (en) * | 1978-01-16 | 1992-05-18 | Wisconsin Alumni Res Found | PROCESS FOR PREPARING A 1-ALFA-HYDROXYVITAMINE D COMPOUND |
US4195027A (en) * | 1978-01-16 | 1980-03-25 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
US4267117A (en) * | 1978-06-19 | 1981-05-12 | The Upjohn Company | Compounds and process |
US4264513A (en) * | 1979-05-21 | 1981-04-28 | Wisconsin Alumni Research Foundation | 1α-hydroxy-25-keto-27-nor-cholecalciferol and processes for preparing same |
-
1984
- 1984-05-09 IE IE114984A patent/IE58277B1/en not_active IP Right Cessation
- 1984-05-09 FR FR8407155A patent/FR2545824B1/en not_active Expired
- 1984-05-09 JP JP59502223A patent/JPS60501261A/en active Granted
- 1984-05-09 BE BE0/212897A patent/BE899612A/en not_active IP Right Cessation
- 1984-05-09 GB GB08411794A patent/GB2139627B/en not_active Expired
-
1985
- 1985-03-22 GB GB08507475A patent/GB2158443B/en not_active Expired
- 1985-03-22 GB GB08507474A patent/GB2158442B/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IE58277B1 (en) | 1993-08-25 |
GB2158442B (en) | 1987-02-04 |
BE899612A (en) | 1984-08-31 |
FR2545824B1 (en) | 1987-11-20 |
GB2139627A (en) | 1984-11-14 |
JPS60501261A (en) | 1985-08-08 |
GB8507475D0 (en) | 1985-05-01 |
GB8507474D0 (en) | 1985-05-01 |
FR2545824A1 (en) | 1984-11-16 |
GB8411794D0 (en) | 1984-06-13 |
IE841149L (en) | 1984-11-09 |
JPH0364498B2 (en) | 1991-10-07 |
GB2158443A (en) | 1985-11-13 |
GB2158442A (en) | 1985-11-13 |
GB2158443B (en) | 1987-02-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
727 | Application made for amendment of specification (sect. 27/1977) | ||
727A | Application for amendment of specification now open to opposition (sect. 27/1977) | ||
727B | Case decided by the comptroller ** specification amended (sect. 27/1977) | ||
SP | Amendment (slips) printed | ||
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20030509 |