SG11202009371WA - Methods for treating atopic dermatitis by administering an il-4r inhibitor - Google Patents

Methods for treating atopic dermatitis by administering an il-4r inhibitor

Info

Publication number
SG11202009371WA
SG11202009371WA SG11202009371WA SG11202009371WA SG11202009371WA SG 11202009371W A SG11202009371W A SG 11202009371WA SG 11202009371W A SG11202009371W A SG 11202009371WA SG 11202009371W A SG11202009371W A SG 11202009371WA SG 11202009371W A SG11202009371W A SG 11202009371WA
Authority
SG
Singapore
Prior art keywords
administering
inhibitor
methods
atopic dermatitis
treating atopic
Prior art date
Application number
SG11202009371WA
Other languages
English (en)
Inventor
Ashish Bansal
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of SG11202009371WA publication Critical patent/SG11202009371WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
SG11202009371WA 2018-05-13 2019-05-10 Methods for treating atopic dermatitis by administering an il-4r inhibitor SG11202009371WA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862670824P 2018-05-13 2018-05-13
US201962840493P 2019-04-30 2019-04-30
PCT/US2019/031801 WO2019222055A1 (fr) 2018-05-13 2019-05-10 Méthodes de traitement de la dermatite atopique par administration d'un inhibiteur de l'il-4r

Publications (1)

Publication Number Publication Date
SG11202009371WA true SG11202009371WA (en) 2020-10-29

Family

ID=66641513

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009371WA SG11202009371WA (en) 2018-05-13 2019-05-10 Methods for treating atopic dermatitis by administering an il-4r inhibitor

Country Status (12)

Country Link
US (2) US11292847B2 (fr)
EP (1) EP3793597A1 (fr)
JP (2) JP2021523188A (fr)
KR (1) KR20210010518A (fr)
CN (1) CN112153982A (fr)
AU (1) AU2019270940A1 (fr)
BR (1) BR112020020387A2 (fr)
CA (1) CA3099066A1 (fr)
MA (1) MA52624A (fr)
MX (1) MX2020012064A (fr)
SG (1) SG11202009371WA (fr)
WO (1) WO2019222055A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI697334B (zh) 2013-06-04 2020-07-01 美商再生元醫藥公司 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
TWI634900B (zh) 2013-07-11 2018-09-11 再生元醫藥公司 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法
AU2015222951B2 (en) 2014-02-28 2020-06-11 Regeneron Pharmaceuticals, Inc. Methods for treating skin infection by administering an IL-4R antagonist
CN107474134B (zh) 2016-06-08 2021-07-27 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
JP2019531273A (ja) 2016-09-01 2019-10-31 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. Il−4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法
US11053309B2 (en) 2017-08-04 2021-07-06 Regeneron Pharmaceuticals, Inc. Methods for treating active eosinophilic esophagitis
PT3515465T (pt) 2017-08-18 2024-03-04 Regeneron Pharma Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r
EP3941589A1 (fr) 2019-03-21 2022-01-26 Regeneron Pharmaceuticals, Inc. Combinaison d'inhibiteurs de la voie il-4/il-13 et d'ablation de plasmocytes pour traiter une allergie
CN114173816A (zh) * 2019-08-05 2022-03-11 瑞泽恩制药公司 通过施用il-4r拮抗剂治疗特应性皮炎的方法
US11504426B2 (en) 2019-08-05 2022-11-22 Regeneron Pharmaceuticals, Inc. Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8808015D0 (en) 1988-04-06 1988-05-05 Ritter M A Chemical compounds
WO1990005183A1 (fr) 1988-10-31 1990-05-17 Immunex Corporation Recepteurs d'interleukine-4
EP0668774A1 (fr) 1991-05-03 1995-08-30 Seragen, Inc. Molecules ciblees sur un recepteur de l'interleukine destinees a traiter l'arthrite inflammatoire
JP3315427B2 (ja) 1992-03-05 2002-08-19 大日本除蟲菊株式会社 皮膚炎治療剤
US5714146A (en) 1992-08-26 1998-02-03 Board Of Regents Of The University Of Washington IL-4 bone therapy
EP0604693A1 (fr) 1992-12-29 1994-07-06 Schering-Plough Anticorps monoclonaux contre le récepteur de l'interleukine-4 humain et hydridomes les produisant
ZA946875B (en) 1993-09-07 1995-07-06 Smithkline Beecham Corp Recombinant il4 antibodies useful in treatment of il4 mediated disorders
ES2259478T3 (es) 1998-09-18 2006-10-01 Dynavax Technologies Corporation Metodos para tratar trastornos asociados con la ige y composiciones para este uso.
ES2382891T3 (es) 2000-05-26 2012-06-14 Immunex Corporation Uso de anticuerpos IL-4R y sus composiciones
US7879328B2 (en) 2000-06-16 2011-02-01 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator
KR100572408B1 (ko) 2000-07-26 2006-04-19 가부시키가이샤 호오도 진양성 조성물 및 창상치유촉진 조성물
US20030103938A1 (en) 2001-05-09 2003-06-05 Alk-Abello A/S Pharmaceutical compositions for preventing or treating Th1 and Th2 cell related diseases by modulating the Th1/Th2 ratio
JP2004529180A (ja) 2001-05-11 2004-09-24 ノバルティス アクチエンゲゼルシャフト IgE関連障害を処置するのに使用するための組成物
AU2002339121B2 (en) 2001-05-23 2007-03-22 Duotol Ab Suppression of allergic reactions by transdermal administration of allergens in conjunction with or conjugated to toxin subunits or fragments thereof
EP2298717B1 (fr) 2001-11-30 2015-10-28 Biogen MA Inc. Anticorps dirigés contre des protéines chimiotactiques
DK1527100T3 (da) 2002-03-29 2009-09-07 Schering Corp Humane monoklonale antistoffer mod interleukin-5 og fremgangsm der og sammens tninger omfattende samme
WO2004070011A2 (fr) 2003-02-01 2004-08-19 Tanox, Inc. Anticorps ige anti-humains a affinite elevee
US7923209B2 (en) 2003-03-14 2011-04-12 Anergis, S.A. Allergen peptide fragments and use thereof
ES2383809T3 (es) 2003-11-07 2012-06-26 Immunex Corporation Anticuerpos que se unen al receptor de interleucina 4
US7884054B2 (en) 2003-12-22 2011-02-08 Amgen Inc. Methods for identifying functional antibodies
JP2008504806A (ja) 2004-02-27 2008-02-21 リジェネロン・ファーマシューティカルズ・インコーポレイテッド Il−4/il−13特異的ポリペプチドおよびその治療上の使用
US20090098142A1 (en) 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
TWI307630B (en) 2004-07-01 2009-03-21 Glaxo Group Ltd Immunoglobulins
JP5234445B2 (ja) 2004-10-05 2013-07-10 源一郎 杣 薬剤
WO2006083390A2 (fr) 2004-12-07 2006-08-10 Children's Hospital Medical Center Eotaxine-3 dans l'oesophagite eosinophile
TW200902555A (en) 2005-01-03 2009-01-16 Hoffmann La Roche Antibodies against IL-13 receptor alpha 1 and uses thereof
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
JP4221018B2 (ja) 2006-08-31 2009-02-12 トヨタ自動車株式会社 頭部保護エアバッグ装置
US7608693B2 (en) 2006-10-02 2009-10-27 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human IL-4 receptor
EP2069403B1 (fr) 2006-10-02 2014-05-07 Regeneron Pharmaceuticals, Inc. Anticorps humains à haute affinité vis-à-vis du récepteur il-4 humain
ES2478242T3 (es) 2007-03-22 2014-07-21 Genentech, Inc. Anticuerpos anti IgE apoptóticos que se unen con el IgE unido a membrana
EP2022507A1 (fr) 2007-08-07 2009-02-11 Universität Hamburg Compositions d'anticorps spécifiques pour les épitopes des lgE, lgG4 et lgA en tant qu'outils pour la création de molécules hypoallergéniques pour l'immunothérapie spécifique
US8637239B2 (en) 2007-11-05 2014-01-28 The Board Of Trustees Of The University Of Illinois Minimally-invasive measurement of esophageal inflammation
US8092804B2 (en) 2007-12-21 2012-01-10 Medimmune Limited Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
DE202008006598U1 (de) 2008-04-11 2008-10-02 Alk-Abelló A/S Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung
US20090264392A1 (en) 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
US20120004205A1 (en) 2008-12-01 2012-01-05 Cincinnati Children's Hospital Medical Center Il-13 induced gene signature for eosinophilic esophagitis
WO2010120524A2 (fr) 2009-03-31 2010-10-21 Altair Therapeutics, Inc. Procédés de modulation d'une réponse immunitaire à une infection virale
US8497528B2 (en) 2010-05-06 2013-07-30 Taiwan Semiconductor Manufacturing Company, Ltd. Method for fabricating a strained structure
WO2011026966A2 (fr) 2009-09-07 2011-03-10 Dbv Technologies Méthode de traitement d'oesophagite éosinophile
US8993347B2 (en) 2009-12-17 2015-03-31 Cornell University Methods for detecting antibodies in mucosal samples and device for sampling mucosal material
EP2585075B8 (fr) 2010-06-24 2021-09-22 ViroPharma Biologics LLC Méthodes de traitement de l'inflammation oesophagienne
CA2813587C (fr) 2010-10-06 2019-01-15 Regeneron Pharmaceuticals, Inc. Formulations stabilisees contenant des anticorps anti-recepteur de l'interleukine-4 (il-4r)
RU2453303C1 (ru) 2010-12-23 2012-06-20 Общество с ограниченной ответственностью "ЦитоНИР" (ООО "ЦитоНИР") Фармацевтическая композиция для лечения атопического дерматита
EP2661631A4 (fr) 2011-01-06 2014-05-21 Childrens Hosp Medical Center Profils d'expression de cytokine sophagienne dans l' sophagite à éosinophiles
US20130052190A1 (en) 2011-02-22 2013-02-28 Oxagen Limited CRTH2 Antagonists for Treatment of Eosinophilic Diseases and Conditions
US9928344B2 (en) 2011-06-21 2018-03-27 Children's Hospital Medical Center Diagnostic methods of eosinophilic esophagitis
WO2013051928A1 (fr) 2011-10-06 2013-04-11 N.V. Nutricia Traitement de l'œsophagite à éosinophiles
EP2790696A1 (fr) 2011-12-16 2014-10-22 Atopix Therapeutics Limited Combinaison d'un antagoniste de crth2 et d'un inhibiteur de pompe à protons pour le traitement de l' sophagite à éosinophiles
KR20140119777A (ko) 2012-01-31 2014-10-10 제넨테크, 인크. 항-ig-e m1'' 항체 및 그의 사용 방법
WO2013155010A1 (fr) 2012-04-09 2013-10-17 Children's Hospital Medical Center Biomarqueurs non invasifs pour l'œsophagite éosinophile
WO2014031610A1 (fr) 2012-08-21 2014-02-27 Sanofi Procédés permettant de traiter ou d'empêcher l'asthme par administration d'un antagoniste du récepteur à l'interleukine 4 (il-4r)
EP4374919A2 (fr) 2012-09-07 2024-05-29 Regeneron Pharmaceuticals, Inc. Méthodes de traitement de la dermatite atopique par administration d'un antagoniste de l'il-4r
US10132809B2 (en) 2012-10-10 2018-11-20 Rhote Island Hospital Differential expression of protein markers for the diagnosis and treatment of eosinophilic esophagitis
US10077315B2 (en) 2013-02-05 2018-09-18 Engmab Sàrl Bispecific antibodies against CD3 and BCMA
TWI697334B (zh) 2013-06-04 2020-07-01 美商再生元醫藥公司 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
US10059771B2 (en) 2013-06-21 2018-08-28 Sanofi Biotechnology Methods for treating nasal polyposis by administering an IL-4R antagonist
TWI634900B (zh) 2013-07-11 2018-09-11 再生元醫藥公司 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法
CA2940295A1 (fr) 2014-02-21 2015-08-27 Sanofi Biotechnology Methodes de traitement ou de prevention de l'asthme par administration d'un antagoniste d'il-4 r
AU2015222951B2 (en) 2014-02-28 2020-06-11 Regeneron Pharmaceuticals, Inc. Methods for treating skin infection by administering an IL-4R antagonist
CA2967602A1 (fr) 2014-11-14 2016-05-19 Sanofi Biotechnology Methodes de traitement de la sinusite chronique avec polypose nasale par administration d'un antagoniste d'il-4r
KR20180110089A (ko) 2016-02-19 2018-10-08 리제너론 파아마슈티컬스, 인크. Il-4r 길항제를 투여함으로써 백신의 효능을 향상시키는 방법
CN107474134B (zh) 2016-06-08 2021-07-27 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
TWI728172B (zh) 2016-08-18 2021-05-21 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法
JP2019531273A (ja) 2016-09-01 2019-10-31 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. Il−4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法
US11845803B2 (en) 2017-02-17 2023-12-19 Fred Hutchinson Cancer Center Combination therapies for treatment of BCMA-related cancers and autoimmune disorders
WO2018201051A1 (fr) 2017-04-28 2018-11-01 Novartis Ag Agent ciblant le bcma et polythérapie incluant un inhibiteur de gamma-sécrétase
US11053309B2 (en) 2017-08-04 2021-07-06 Regeneron Pharmaceuticals, Inc. Methods for treating active eosinophilic esophagitis
PT3515465T (pt) 2017-08-18 2024-03-04 Regeneron Pharma Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r
ES2969049T3 (es) 2017-10-30 2024-05-16 Sanofi Biotechnology Antagonista de IL-4R para uso en un método para tratar o prevenir el asma
EP3941589A1 (fr) 2019-03-21 2022-01-26 Regeneron Pharmaceuticals, Inc. Combinaison d'inhibiteurs de la voie il-4/il-13 et d'ablation de plasmocytes pour traiter une allergie
US11504426B2 (en) 2019-08-05 2022-11-22 Regeneron Pharmaceuticals, Inc. Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist
CN114173816A (zh) 2019-08-05 2022-03-11 瑞泽恩制药公司 通过施用il-4r拮抗剂治疗特应性皮炎的方法
CN115768516A (zh) 2020-05-22 2023-03-07 瑞泽恩制药公司 通过施用il-4r抑制剂治疗嗜酸细胞性食管炎的方法

Also Published As

Publication number Publication date
NZ769607A (en) 2023-11-24
EP3793597A1 (fr) 2021-03-24
MX2020012064A (es) 2021-04-13
JP2021523188A (ja) 2021-09-02
US11292847B2 (en) 2022-04-05
KR20210010518A (ko) 2021-01-27
US20190345253A1 (en) 2019-11-14
JP2024038234A (ja) 2024-03-19
MA52624A (fr) 2021-03-24
AU2019270940A1 (en) 2020-11-26
WO2019222055A1 (fr) 2019-11-21
BR112020020387A2 (pt) 2021-01-19
CN112153982A (zh) 2020-12-29
CA3099066A1 (fr) 2019-11-21
US20220298250A1 (en) 2022-09-22

Similar Documents

Publication Publication Date Title
PT3515465T (pt) Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r
SG11202009371WA (en) Methods for treating atopic dermatitis by administering an il-4r inhibitor
IL289930A (en) Methods for treating atopic dermatitis using an IL-4R antagonist
IL285201A (en) EZH2 inhibitors for the treatment of lymphoma
IL274134A (en) Methods of treating or preventing asthma by administering an IL-4R agonist
IL256056A (en) ezh2 inhibitors for the treatment of lymphoma
EP3413852A4 (fr) Méthodes, compositions et appareils pour le traitement du psoriasis par photothérapie
IL265516A (en) Methods for treating severe allergic dermatitis by administering an il-4r inhibitor
EP3282629A4 (fr) Procédé de déclaration d'état de canal et appareil associé
PT3107575T (pt) Métodos de tratamento e prevenção de asma administrando um antagonista de il-4r
EP3229887A4 (fr) Appareil et procédé pour traiter les maux de tête
EP3268087A4 (fr) Méthodes de traitement du cancer par des inhibiteurs de ror gamma
IL281318A (en) A method for treating medulloblastoma with an EZH2 inhibitor
EP3329018A4 (fr) Méthodes de traitement de troubles médiés par l'hepcidine
EP3134120A4 (fr) Compositions et méthodes pour le traitement de troubles liés aux cytokines
ZA201600048B (en) Method for treating internal arcs
EP3654193A4 (fr) Procédé pour autoriser une valeur de champ d'un champ de formulaire au moyen d'un champ de tierce partie
EP3302695A4 (fr) Procédé et dispositifs de traitement des muscles
EP3244043A4 (fr) Appareil et procédé de commande de soupape rge
EP3262065A4 (fr) Procédés et compositions de traitement des dystroglycanopathies
EP3589370A4 (fr) Méthode de traitement de la sclérose en plaques
EP3307775A4 (fr) Méthodes de diagnostic et de traitement de troubles affectifs
EP3250218A4 (fr) Méthodes de traitement de l'obésité
EP3139911A4 (fr) Procédé de traitement d'une stéatohépatite non alcoolique avancée
MX2016009541A (es) Metodo para tratar vajilla.