SG11202009314XA - Heterocyclic compound - Google Patents

Heterocyclic compound

Info

Publication number
SG11202009314XA
SG11202009314XA SG11202009314XA SG11202009314XA SG11202009314XA SG 11202009314X A SG11202009314X A SG 11202009314XA SG 11202009314X A SG11202009314X A SG 11202009314XA SG 11202009314X A SG11202009314X A SG 11202009314XA SG 11202009314X A SG11202009314X A SG 11202009314XA
Authority
SG
Singapore
Prior art keywords
heterocyclic compound
heterocyclic
compound
Prior art date
Application number
SG11202009314XA
Other languages
English (en)
Inventor
Yoshinori Yoshida
Kenji Miki
Akira Kaieda
Shigeru Kondo
Hiroshi Nara
Yoshinori Ikeura
Original Assignee
Univ Kyoto
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyoto, Takeda Pharmaceuticals Co filed Critical Univ Kyoto
Publication of SG11202009314XA publication Critical patent/SG11202009314XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657Cardiomyocytes; Heart cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999Small molecules not provided for elsewhere

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
SG11202009314XA 2018-03-30 2019-03-28 Heterocyclic compound SG11202009314XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018069872 2018-03-30
PCT/JP2019/013529 WO2019189553A1 (ja) 2018-03-30 2019-03-28 複素環化合物

Publications (1)

Publication Number Publication Date
SG11202009314XA true SG11202009314XA (en) 2020-10-29

Family

ID=68059192

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009314XA SG11202009314XA (en) 2018-03-30 2019-03-28 Heterocyclic compound

Country Status (14)

Country Link
US (1) US11401264B2 (es)
EP (1) EP3778587B1 (es)
JP (1) JP7257698B2 (es)
CN (1) CN111918866B (es)
AU (1) AU2019241702B2 (es)
BR (1) BR112020019579A8 (es)
CA (1) CA3095717A1 (es)
CO (1) CO2020012101A2 (es)
ES (1) ES2966207T3 (es)
IL (1) IL277340B2 (es)
MX (1) MX2020010184A (es)
SG (1) SG11202009314XA (es)
TW (1) TWI820104B (es)
WO (1) WO2019189553A1 (es)

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9210098B (sl) * 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo
US5594003A (en) 1991-02-06 1997-01-14 Dr. Karl Thomae Gmbh Tetrahydroimidazo[1,2-a]pyridin-2-yl-(benzimidazol-1-yl)-methyl-biphenyls useful as angiotensin-II antagonists
US5602127A (en) 1991-02-06 1997-02-11 Karl Thomae Gmbh (Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls useful as angiotensin-II antagonists
US5614519A (en) 1991-02-06 1997-03-25 Karl Thomae Gmbh (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists
DE4212748A1 (de) 1992-04-16 1993-10-21 Thomae Gmbh Dr K Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US7727762B2 (en) 2003-10-03 2010-06-01 Keiichi Fukuda Method of inducing the differentiation of stem cells into myocardial cells
MXPA06011371A (es) 2004-04-10 2006-12-20 Henkel Kgaa Tubo para rizar el cabello.
CN101228264B (zh) 2005-06-22 2017-12-26 阿斯特利亚斯生物治疗股份公司 使灵长类多能干细胞分化成心肌细胞系细胞
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
BRPI0619794B8 (pt) 2005-12-13 2022-06-14 Univ Kyoto Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas
CN101426902B (zh) 2006-04-28 2013-03-27 第一三共株式会社 将多能性干细胞分化诱导成心肌细胞的方法
US7661738B2 (en) 2006-11-28 2010-02-16 Veritainer Corporation Radiation detection unit for mounting a radiation sensor to a container crane
WO2008124133A1 (en) 2007-04-07 2008-10-16 Whitehead Institute For Biomedical Research Reprogramming of somatic cells
WO2008151058A2 (en) 2007-05-30 2008-12-11 The General Hospital Corporation Methods of generating pluripotent cells from somatic cells
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
WO2009118928A1 (en) 2008-03-26 2009-10-01 Kyoto University Efficient production and use of highly cardiogenic progenitors and cardiomyocytes from embryonic and induced pluripotent stem cells
CN103209968B (zh) * 2010-08-26 2015-08-05 国立大学法人京都大学 多能干细胞心肌细胞分化促进剂
US9499790B2 (en) 2010-08-26 2016-11-22 Kyoto University Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
JP5840855B2 (ja) 2011-03-30 2016-01-06 学校法人東京女子医科大学 胚性幹細胞から心筋シートを製造する方法
US9764063B2 (en) 2012-03-15 2017-09-19 Iheart Japan Corporation Method for producing mixed cell population of cardiomyocytes and vascular cells from induced pluripotent stem cell
EP3006559B1 (en) 2013-05-31 2019-11-06 iHeart Japan Corporation Layered cell sheet incorporating hydrogel
CN105473708A (zh) * 2013-06-11 2016-04-06 普鲁瑞欧米克斯有限公司 用于使衍生自多能哺乳动物干细胞的心肌细胞成熟的培养基组合物
EP3150705B1 (en) 2014-05-30 2019-05-15 Kyoto University Method for inducing myocardial differentiation of pluripotent stem cells using low-molecular compound
EP3219790B1 (en) 2014-11-12 2021-08-04 Terumo Kabushiki Kaisha Myocardial cell sheet
JP2017060422A (ja) 2015-09-24 2017-03-30 国立大学法人 東京大学 成熟した心筋細胞を分化誘導させる方法
JP6702134B2 (ja) 2016-10-27 2020-05-27 トヨタ自動車株式会社 電動車両

Also Published As

Publication number Publication date
RU2020135574A (ru) 2022-05-04
EP3778587C0 (en) 2023-10-04
CO2020012101A2 (es) 2020-12-10
BR112020019579A8 (pt) 2022-10-18
CN111918866B (zh) 2023-07-04
EP3778587A4 (en) 2021-10-06
IL277340B1 (en) 2024-03-01
TWI820104B (zh) 2023-11-01
TW201942354A (zh) 2019-11-01
BR112020019579A2 (pt) 2021-01-12
CN111918866A (zh) 2020-11-10
JP7257698B2 (ja) 2023-04-14
WO2019189553A1 (ja) 2019-10-03
MX2020010184A (es) 2020-10-28
KR20200139210A (ko) 2020-12-11
US11401264B2 (en) 2022-08-02
AU2019241702A1 (en) 2020-10-08
IL277340A (en) 2020-10-29
IL277340B2 (en) 2024-07-01
CA3095717A1 (en) 2019-10-03
AU2019241702B2 (en) 2023-07-27
US20210024512A1 (en) 2021-01-28
JPWO2019189553A1 (ja) 2021-03-25
EP3778587A1 (en) 2021-02-17
EP3778587B1 (en) 2023-10-04
ES2966207T3 (es) 2024-04-18

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