SG11202009314XA - Heterocyclic compound - Google Patents

Heterocyclic compound

Info

Publication number
SG11202009314XA
SG11202009314XA SG11202009314XA SG11202009314XA SG11202009314XA SG 11202009314X A SG11202009314X A SG 11202009314XA SG 11202009314X A SG11202009314X A SG 11202009314XA SG 11202009314X A SG11202009314X A SG 11202009314XA SG 11202009314X A SG11202009314X A SG 11202009314XA
Authority
SG
Singapore
Prior art keywords
heterocyclic compound
heterocyclic
compound
Prior art date
Application number
SG11202009314XA
Inventor
Yoshinori Yoshida
Kenji Miki
Akira Kaieda
Shigeru Kondo
Hiroshi Nara
Yoshinori Ikeura
Original Assignee
Univ Kyoto
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyoto, Takeda Pharmaceuticals Co filed Critical Univ Kyoto
Publication of SG11202009314XA publication Critical patent/SG11202009314XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657Cardiomyocytes; Heart cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999Small molecules not provided for elsewhere

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
SG11202009314XA 2018-03-30 2019-03-28 Heterocyclic compound SG11202009314XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018069872 2018-03-30
PCT/JP2019/013529 WO2019189553A1 (en) 2018-03-30 2019-03-28 Heterocyclic compound

Publications (1)

Publication Number Publication Date
SG11202009314XA true SG11202009314XA (en) 2020-10-29

Family

ID=68059192

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009314XA SG11202009314XA (en) 2018-03-30 2019-03-28 Heterocyclic compound

Country Status (15)

Country Link
US (1) US11401264B2 (en)
EP (1) EP3778587B1 (en)
JP (1) JP7257698B2 (en)
KR (1) KR102708268B1 (en)
CN (1) CN111918866B (en)
AU (1) AU2019241702B2 (en)
BR (1) BR112020019579A8 (en)
CA (1) CA3095717A1 (en)
CO (1) CO2020012101A2 (en)
ES (1) ES2966207T3 (en)
IL (1) IL277340B2 (en)
MX (1) MX2020010184A (en)
SG (1) SG11202009314XA (en)
TW (1) TWI820104B (en)
WO (1) WO2019189553A1 (en)

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591762A (en) 1991-02-06 1997-01-07 Dr. Karl Thomae Gmbh Benzimidazoles useful as angiotensin-11 antagonists
US5594003A (en) 1991-02-06 1997-01-14 Dr. Karl Thomae Gmbh Tetrahydroimidazo[1,2-a]pyridin-2-yl-(benzimidazol-1-yl)-methyl-biphenyls useful as angiotensin-II antagonists
SI9210098B (en) * 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoles, drugs with this compounds, and process for their preparation
US5602127A (en) 1991-02-06 1997-02-11 Karl Thomae Gmbh (Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls useful as angiotensin-II antagonists
DE4212748A1 (en) 1992-04-16 1993-10-21 Thomae Gmbh Dr K New 1-bi:phenyl:methyl- benzimidazole derivs. - used as angiotensin antagonists, e.g. for treating cardiovascular, pulmonary and CNS disorders e.g. Alzheimer's disease, ischaemia etc.
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
RU2392315C2 (en) 2003-10-03 2010-06-20 Кейити ФУКУДА Method of stem cells differentiation into miocardial cells induction
DE502004001104D1 (en) 2004-04-10 2006-09-14 Henkel Kgaa CURLER
JP5560393B2 (en) 2005-06-22 2014-07-23 アステリアス バイオセラピューティクス インコーポレイテッド Differentiation of primate pluripotent stem cells into cardiomyocyte lineage cells
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
EP3418297B1 (en) 2005-12-13 2023-04-05 Kyoto University Nuclear reprogramming factor
BRPI0710949A2 (en) 2006-04-28 2012-03-06 Asubio Pharma Co., Ltd. METHOD FOR INDUCING PLURIPOTENT STEM CELL DIFFERENTIATION IN CARDIOMYOCYTES
US7661738B2 (en) 2006-11-28 2010-02-16 Veritainer Corporation Radiation detection unit for mounting a radiation sensor to a container crane
EP2145000A4 (en) 2007-04-07 2010-05-05 Whitehead Biomedical Inst Reprogramming of somatic cells
EP2164951A2 (en) 2007-05-30 2010-03-24 The General Hospital Corporation Methods of generating pluripotent cells from somatic cells
JP2008307007A (en) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag Human pluripotent stem cell induced from human tissue-originated undifferentiated stem cell after birth
US8765465B2 (en) 2008-03-26 2014-07-01 Kyoto University Efficient production and use of highly cardiogenic progenitors and cardiomyocytes from embryonic and induced pluripotent stem cells
US9499790B2 (en) 2010-08-26 2016-11-22 Kyoto University Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
JP5930205B2 (en) * 2010-08-26 2016-06-08 国立大学法人京都大学 Promoting myocardial differentiation of pluripotent stem cells
JP5840855B2 (en) 2011-03-30 2016-01-06 学校法人東京女子医科大学 Method for producing myocardial sheet from embryonic stem cells
JP5920741B2 (en) 2012-03-15 2016-05-18 iHeart Japan株式会社 Method for producing myocardial and vascular mixed cells from induced pluripotent stem cells
CN105247041B (en) 2013-05-31 2018-04-20 爱心细胞有限公司 Group enters to have the stacking cell patch of hydrogel
EP3008172B1 (en) * 2013-06-11 2020-05-06 Ncardia B.V. Culture medium compositions for maturating cardiomyocytes derived from pluripotent mammalian stem cells
JP6651218B2 (en) * 2014-05-30 2020-02-19 国立大学法人京都大学 Induction of myocardial differentiation of pluripotent stem cells using low molecular weight compounds
EP3219790B1 (en) 2014-11-12 2021-08-04 Terumo Kabushiki Kaisha Myocardial cell sheet
JP2017060422A (en) * 2015-09-24 2017-03-30 国立大学法人 東京大学 Method for differentiation induction of mature cardiomyocyte
JP6702134B2 (en) 2016-10-27 2020-05-27 トヨタ自動車株式会社 Electric vehicle

Also Published As

Publication number Publication date
RU2020135574A (en) 2022-05-04
JP7257698B2 (en) 2023-04-14
CN111918866B (en) 2023-07-04
BR112020019579A2 (en) 2021-01-12
AU2019241702A1 (en) 2020-10-08
ES2966207T3 (en) 2024-04-18
JPWO2019189553A1 (en) 2021-03-25
CN111918866A (en) 2020-11-10
EP3778587C0 (en) 2023-10-04
WO2019189553A1 (en) 2019-10-03
MX2020010184A (en) 2020-10-28
KR102708268B1 (en) 2024-09-20
TWI820104B (en) 2023-11-01
CA3095717A1 (en) 2019-10-03
BR112020019579A8 (en) 2022-10-18
EP3778587A4 (en) 2021-10-06
TW201942354A (en) 2019-11-01
AU2019241702B2 (en) 2023-07-27
US20210024512A1 (en) 2021-01-28
IL277340B1 (en) 2024-03-01
IL277340B2 (en) 2024-07-01
KR20200139210A (en) 2020-12-11
CO2020012101A2 (en) 2020-12-10
EP3778587B1 (en) 2023-10-04
US11401264B2 (en) 2022-08-02
EP3778587A1 (en) 2021-02-17
IL277340A (en) 2020-10-29

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