SG11201709634QA - Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity - Google Patents
Nitrogen-containing tricyclic derivative having hiv replication inhibitory activityInfo
- Publication number
- SG11201709634QA SG11201709634QA SG11201709634QA SG11201709634QA SG11201709634QA SG 11201709634Q A SG11201709634Q A SG 11201709634QA SG 11201709634Q A SG11201709634Q A SG 11201709634QA SG 11201709634Q A SG11201709634Q A SG 11201709634QA SG 11201709634Q A SG11201709634Q A SG 11201709634QA
- Authority
- SG
- Singapore
- Prior art keywords
- nitrogen
- inhibitory activity
- hiv replication
- tricyclic derivative
- containing tricyclic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015109547 | 2015-05-29 | ||
| JP2015170222 | 2015-08-31 | ||
| JP2015223036 | 2015-11-13 | ||
| JP2016054215 | 2016-03-17 | ||
| PCT/JP2016/065702 WO2016194806A1 (fr) | 2015-05-29 | 2016-05-27 | Dérivé tricyclique contenant de l'azote présentant une activité inhibitrice de la réplication du vih |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201709634QA true SG11201709634QA (en) | 2017-12-28 |
Family
ID=57442245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201709634QA SG11201709634QA (en) | 2015-05-29 | 2016-05-27 | Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10494380B2 (fr) |
| EP (1) | EP3305789A4 (fr) |
| JP (2) | JP6614585B2 (fr) |
| KR (1) | KR20180011267A (fr) |
| CN (2) | CN111138458A (fr) |
| AU (1) | AU2016271762B2 (fr) |
| BR (1) | BR112017025367A2 (fr) |
| CA (1) | CA2987384A1 (fr) |
| HK (1) | HK1253539A1 (fr) |
| IL (1) | IL255580B (fr) |
| MA (1) | MA43120A (fr) |
| MX (1) | MX2017015256A (fr) |
| RU (1) | RU2720145C2 (fr) |
| SG (1) | SG11201709634QA (fr) |
| TW (1) | TWI700284B (fr) |
| WO (1) | WO2016194806A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2970282B1 (fr) | 2013-03-15 | 2019-08-21 | Incyte Holdings Corporation | Hétérocycles tricycliques en tant qu'inhibiteurs de protéine bet |
| EP3019502B1 (fr) | 2013-07-08 | 2017-05-17 | Incyte Holdings Corporation | Hétérocycles tricycliques en tant qu'inhibiteurs de protéines bet |
| US9399640B2 (en) | 2013-11-26 | 2016-07-26 | Incyte Corporation | Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors |
| US9309246B2 (en) | 2013-12-19 | 2016-04-12 | Incyte Corporation | Tricyclic heterocycles as BET protein inhibitors |
| MY180775A (en) | 2014-04-23 | 2020-12-09 | Incyte Corp | 1h-pyrrolo[2,3-c]pyridin-7(6h)-ones and pyrazolo[3,4-c]pyridin-7(6h)-ones as inhibitors of bet proteins |
| JP6599979B2 (ja) | 2014-09-15 | 2019-10-30 | インサイト・コーポレイション | Ｂｅｔタンパク質阻害剤として用いるための三環式複素環化合物 |
| TW201722966A (zh) | 2015-10-29 | 2017-07-01 | 英塞特公司 | Bet蛋白質抑制劑之非晶固體形式 |
| EP4234554A3 (fr) | 2016-06-20 | 2023-12-27 | Incyte Corporation | Formes cristallines solides d'un inhibiteur bet |
| JP7290356B2 (ja) * | 2019-01-23 | 2023-06-13 | アビスコ セラピューティクス カンパニー リミテッド | １，２，３，４－テトラヒドロキノキサリン誘導体、その製造方法および使用 |
| TW202133858A (zh) | 2019-11-28 | 2021-09-16 | 日商鹽野義製藥股份有限公司 | 以組合整合酶阻礙劑及抗ｈｉｖ藥為特徵之ｈｉｖ感染症的預防及治療用醫藥 |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
| CN112409493B (zh) * | 2020-08-12 | 2022-09-30 | 浙江工业大学 | 一种重组融合酶及其在乙醛酸甲酯合成中的应用 |
| CN114075212B (zh) * | 2020-08-14 | 2023-05-12 | 江苏恒瑞医药股份有限公司 | 稠合三环类衍生物、其制备方法及其在医药上的应用 |
Family Cites Families (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000505451A (ja) | 1996-02-21 | 2000-05-09 | ダーウィン・ディスカバリー・リミテッド | キノロン類およびこれらの治療的使用 |
| AU710825B2 (en) * | 1996-02-21 | 1999-09-30 | Darwin Discovery Limited | Quinolones and their therapeutic use |
| US5792774A (en) | 1996-02-21 | 1998-08-11 | Chiroscience Limited | Quinolones and their therapeutic use |
| DE19946289A1 (de) * | 1999-09-28 | 2001-03-29 | Basf Ag | Benzodiazepin-Derivate, deren Herstellung und Anwendung |
| WO2002012239A1 (fr) * | 2000-08-08 | 2002-02-14 | Sanofi-Synthelabo | Derives de benzimidazole, leur preparation et leur application en therapeutique |
| US7026311B2 (en) | 2002-01-10 | 2006-04-11 | Abbott Gmbh & Co., Kg | Dibenzodiazepine derivatives, their preparation and use |
| JP2004256531A (ja) * | 2003-02-07 | 2004-09-16 | Takeda Chem Ind Ltd | 三環性化合物、その製造法および用途 |
| EP1593681A4 (fr) | 2003-02-07 | 2007-09-05 | Takeda Pharmaceutical | Compose tricyclique, procede de production et utilisation dudit compose |
| AR056918A1 (es) | 2005-01-10 | 2007-11-07 | Tibotec Pharm Ltd | 2-oxo-3-ciano-1,6a-diaza-tetrahidro-fluorantenos 1,5,6-sustituidos, proceso de preparacion del compuesto y composicion farmaceutica |
| MX2008001152A (es) | 2005-08-05 | 2008-04-02 | Astrazeneca Ab | Benzimidazoles triciclicos y su uso como moduladores del receptor de glutamato metabotropico. |
| US7939545B2 (en) | 2006-05-16 | 2011-05-10 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
| RU2503679C2 (ru) | 2007-11-15 | 2014-01-10 | Джилид Сайенсиз, Инк. | Ингибиторы репликации вируса иммунодефицита человека |
| SI2220076T1 (sl) | 2007-11-15 | 2012-05-31 | Gilead Sciences Inc | Inhibitorji replikacije virusa humane imunske pomankljivosti |
| WO2009062308A1 (fr) | 2007-11-16 | 2009-05-22 | Boehringer Ingelheim International Gmbh | Inhibiteurs de la réplication du virus de l'immunodéficience humaine |
| EA201200631A1 (ru) | 2007-11-16 | 2012-11-30 | Джилид Сайенсиз, Инк. | Ингибиторы репликации вируса иммунодефицита человека |
| US8338441B2 (en) * | 2009-05-15 | 2012-12-25 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| GB0908394D0 (en) | 2009-05-15 | 2009-06-24 | Univ Leuven Kath | Novel viral replication inhibitors |
| GB0913636D0 (en) | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
| SG181423A1 (en) | 2009-12-23 | 2012-07-30 | Univ Leuven Kath | Novel antiviral compounds |
| PE20130525A1 (es) | 2010-07-02 | 2013-05-05 | Gilead Sciences Inc | Derivados de acido 2 quinolinil acetico como compuestos antivirales frente a vih |
| MA34397B1 (fr) * | 2010-07-02 | 2013-07-03 | Gilead Sciences Inc | Dérivés d'acide napht-2-ylacétique dans le traitement du sida |
| US8633200B2 (en) | 2010-09-08 | 2014-01-21 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| CA2817896A1 (fr) | 2010-11-15 | 2012-05-24 | Viiv Healthcare Uk Limited | Inhibiteurs de la replication du vih |
| EP2640705A2 (fr) | 2010-11-15 | 2013-09-25 | Katholieke Universiteit Leuven | Nouveaux composés antiviraux |
| WO2012102985A1 (fr) | 2011-01-24 | 2012-08-02 | Glaxosmithkline Llc | Composés d'isoquinoléine et procédés pour traiter le vih |
| EP2508511A1 (fr) | 2011-04-07 | 2012-10-10 | Laboratoire Biodim | Inhibiteurs de la réplication virale, leur procédé de préparation et leurs utilisations thérapeutiques |
| EP2511273B8 (fr) * | 2011-04-15 | 2019-06-26 | Hivih | Inhibiteurs de la réplication virale, leur procédé de préparation et leurs utilisations thérapeutiques |
| CA2833377C (fr) | 2011-04-21 | 2019-02-12 | Gilead Sciences, Inc. | Composes benzothiazoles et leur utilisation pharmaceutique |
| WO2013002357A1 (fr) | 2011-06-30 | 2013-01-03 | 塩野義製薬株式会社 | Inhibiteur de réplication du vih |
| ES2624984T3 (es) | 2011-07-15 | 2017-07-18 | Viiv Healthcare Uk Limited | Derivados de ácido 2-(pirrolo[2,3-b]piridin-5-il)-2-(t-butoxi)-acético como inhibidores de la replicación del VIH para el tratamiento del SIDA |
| US8791108B2 (en) | 2011-08-18 | 2014-07-29 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| WO2013043553A1 (fr) | 2011-09-22 | 2013-03-28 | Glaxosmithkline Llc | Composés pyrrolopyridinones et méthodes de traitement du vih |
| US9199959B2 (en) | 2011-10-25 | 2015-12-01 | Shionogi & Co., Ltd. | HIV replication inhibitor |
| PT2781519T (pt) | 2011-11-15 | 2019-12-17 | St Pharm Co Ltd | Novo derivado de pirrolopiridina antiviral e um método de produção do mesmo |
| US9284323B2 (en) | 2012-01-04 | 2016-03-15 | Gilead Sciences, Inc. | Naphthalene acetic acid derivatives against HIV infection |
| US9376392B2 (en) | 2012-01-04 | 2016-06-28 | Gilead Sciences, Inc. | 2-(tert-butoxy)-2-(7-methylquinolin-6-yl) acetic acid derivatives for treating AIDS |
| US8629276B2 (en) | 2012-02-15 | 2014-01-14 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| US9034882B2 (en) | 2012-03-05 | 2015-05-19 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| US9006235B2 (en) | 2012-03-06 | 2015-04-14 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| WO2013157622A1 (fr) | 2012-04-19 | 2013-10-24 | 塩野義製薬株式会社 | Inhibiteur de la réplication du vih |
| PE20141558A1 (es) | 2012-04-20 | 2014-11-06 | Gilead Sciences Inc | Derivados de acido benzotiazol-6-il acetico y su uso para tratar una infeccion por vih |
| CA2876370A1 (fr) * | 2012-07-12 | 2014-01-16 | Viiv Healthcare Uk Limited | Composes et procedes de traitement du vih |
| US8906929B2 (en) | 2012-08-16 | 2014-12-09 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| EP2716639A1 (fr) | 2012-10-05 | 2014-04-09 | Laboratoire Biodim | Inhibiteurs de la réplication virale, leur procédé de préparation et leurs utilisations thérapeutiques |
| EP2716632A1 (fr) | 2012-10-05 | 2014-04-09 | Laboratoire Biodim | Inhibiteurs de la réplication virale, leur procédé de préparation et leurs utilisations thérapeutiques |
| EP2719685A1 (fr) | 2012-10-11 | 2014-04-16 | Laboratoire Biodim | Inhibiteurs de la réplication virale, leur procédé de préparation et leurs utilisations thérapeutiques |
| TW201441197A (zh) * | 2013-01-31 | 2014-11-01 | Shionogi & Co | Ｈｉｖ複製抑制劑 |
| CN105008358B (zh) | 2013-03-13 | 2017-12-29 | 百时美施贵宝公司 | 人免疫缺陷病毒复制的抑制剂 |
| US9580431B2 (en) | 2013-03-13 | 2017-02-28 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
| CN105189503B (zh) | 2013-03-14 | 2017-03-22 | 百时美施贵宝公司 | 人免疫缺陷病毒复制的抑制剂 |
| WO2015126765A1 (fr) | 2014-02-19 | 2015-08-27 | Bristol-Myers Squibb Company | Inhibiteurs de la réplication du virus de l'immunodéficience humaine |
| WO2015147247A1 (fr) | 2014-03-28 | 2015-10-01 | 塩野義製薬株式会社 | Dérivé tricyclique présentant une activité inhibitrice de la réplication du vih |
| EP3144311A4 (fr) | 2014-05-16 | 2018-01-03 | Shionogi & Co., Ltd. | Dérivé hétérocyclique tricyclique présentant un effet d'inhibition de la réplication du vih |
| WO2015179448A1 (fr) | 2014-05-21 | 2015-11-26 | Gilead Sciences, Inc. | Composés thérapeutiques |
| JP2017521428A (ja) | 2014-07-08 | 2017-08-03 | ヴィーブ ヘルスケア ユーケー リミテッド | ウイルス感染症の治療に使用するためのイソインドリン誘導体 |
| UY36221A (es) | 2014-07-22 | 2016-02-29 | Viiv Healthcare Uk Ltd | Derivados de isoindolinona |
| AU2015306779B2 (en) | 2014-08-27 | 2017-11-02 | VIIV Healthcare UK (NO.5) Ltd | Imidazo[1,2-a]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication |
| TW201720798A (zh) | 2015-09-17 | 2017-06-16 | Ｖｉｉｖ醫療保健英國有限公司 | 苯并氮呯衍生物 |
| EP3383862A1 (fr) | 2015-12-04 | 2018-10-10 | ViiV Healthcare UK Limited | Dérivés d'isoindoline |
| JP2018536001A (ja) | 2015-12-04 | 2018-12-06 | ヴィーブ ヘルスケア ユーケー リミテッド | イソインドリン誘導体 |
| WO2017093930A1 (fr) | 2015-12-04 | 2017-06-08 | Viiv Healthcare Uk Limited | Dérivés d'isoindoline |
| JP2019501143A (ja) | 2015-12-04 | 2019-01-17 | ヴィーブ ヘルスケア ユーケー リミテッド | テトラヒドロイソキノリン誘導体 |
-
2016
- 2016-05-27 US US15/577,795 patent/US10494380B2/en not_active Expired - Fee Related
- 2016-05-27 JP JP2017521897A patent/JP6614585B2/ja not_active Expired - Fee Related
- 2016-05-27 WO PCT/JP2016/065702 patent/WO2016194806A1/fr active Application Filing
- 2016-05-27 MA MA043120A patent/MA43120A/fr unknown
- 2016-05-27 CA CA2987384A patent/CA2987384A1/fr not_active Abandoned
- 2016-05-27 CN CN202010066935.5A patent/CN111138458A/zh active Pending
- 2016-05-27 SG SG11201709634QA patent/SG11201709634QA/en unknown
- 2016-05-27 TW TW105116757A patent/TWI700284B/zh not_active IP Right Cessation
- 2016-05-27 EP EP16803241.5A patent/EP3305789A4/fr not_active Withdrawn
- 2016-05-27 CN CN201680043904.XA patent/CN107922423B/zh not_active Expired - Fee Related
- 2016-05-27 KR KR1020177037486A patent/KR20180011267A/ko unknown
- 2016-05-27 MX MX2017015256A patent/MX2017015256A/es unknown
- 2016-05-27 RU RU2017145082A patent/RU2720145C2/ru active
- 2016-05-27 BR BR112017025367-4A patent/BR112017025367A2/pt active Search and Examination
- 2016-05-27 AU AU2016271762A patent/AU2016271762B2/en not_active Ceased
-
2017
- 2017-11-09 IL IL255580A patent/IL255580B/en active IP Right Grant
-
2018
- 2018-10-05 HK HK18112740.8A patent/HK1253539A1/zh unknown
-
2019
- 2019-10-28 US US16/665,231 patent/US10870661B2/en active Active
- 2019-10-29 JP JP2019196066A patent/JP6797464B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016271762B2 (en) | 2020-01-23 |
| JPWO2016194806A1 (ja) | 2018-03-22 |
| MA43120A (fr) | 2018-09-05 |
| RU2720145C2 (ru) | 2020-04-24 |
| CA2987384A1 (fr) | 2016-12-08 |
| CN107922423A (zh) | 2018-04-17 |
| IL255580A (en) | 2018-01-31 |
| US20180162876A1 (en) | 2018-06-14 |
| US20200055873A1 (en) | 2020-02-20 |
| HK1253539A1 (zh) | 2019-06-21 |
| BR112017025367A2 (pt) | 2018-08-07 |
| WO2016194806A1 (fr) | 2016-12-08 |
| KR20180011267A (ko) | 2018-01-31 |
| TW201706275A (zh) | 2017-02-16 |
| IL255580B (en) | 2020-11-30 |
| CN111138458A (zh) | 2020-05-12 |
| AU2016271762A1 (en) | 2017-11-30 |
| EP3305789A1 (fr) | 2018-04-11 |
| CN107922423B (zh) | 2020-10-27 |
| JP6614585B2 (ja) | 2019-12-04 |
| TWI700284B (zh) | 2020-08-01 |
| JP6797464B2 (ja) | 2020-12-09 |
| RU2017145082A (ru) | 2019-07-01 |
| MX2017015256A (es) | 2018-02-19 |
| EP3305789A4 (fr) | 2018-11-21 |
| RU2017145082A3 (fr) | 2019-10-24 |
| US10494380B2 (en) | 2019-12-03 |
| US10870661B2 (en) | 2020-12-22 |
| JP2020097568A (ja) | 2020-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1253539A1 (zh) | 具有hiv複製抑制作用的含氮三環性衍生物 | |
| IL291598A (en) | History of benzodiazepine cytotoxicity | |
| HK1245253A1 (zh) | Parg抑制化合物 | |
| EP3193667A4 (fr) | Étagères modulaires | |
| ZA201900019B (en) | Pharmaceutical combinations | |
| PL3310784T3 (pl) | Związki tricykliczne i ich zastosowanie jako inhibitory fosfodiesterazy | |
| GB2529856B (en) | Modular furniture system | |
| IL257808B (en) | decarboxylation without water | |
| HK1253011A1 (zh) | 聯合hiv療法 | |
| EP3144311A4 (fr) | Dérivé hétérocyclique tricyclique présentant un effet d'inhibition de la réplication du vih | |
| PL3531872T3 (pl) | Mebel | |
| HK1245796A1 (zh) | 黃嘌呤衍生物 | |
| PT3187071T (pt) | Gaveta | |
| EP3174864A4 (fr) | Composés inhibiteurs de vmat | |
| GB201612404D0 (en) | Vdu | |
| GB201607978D0 (en) | Inhibitory compounds | |
| AU201613667S (en) | Log splitter | |
| GB201610579D0 (en) | Furniture | |
| AU2015904138A0 (en) | Saddle Shelving | |
| GB201517291D0 (en) | Modular furniture system | |
| GB201509287D0 (en) | Modular furniture system | |
| GB201402369D0 (en) | Pair Pursuit |