MA43120A - Dérivé tricyclique contenant de l'azote présentant une activité inhibitrice de la réplication du vih - Google Patents

Dérivé tricyclique contenant de l'azote présentant une activité inhibitrice de la réplication du vih

Info

Publication number
MA43120A
MA43120A MA043120A MA43120A MA43120A MA 43120 A MA43120 A MA 43120A MA 043120 A MA043120 A MA 043120A MA 43120 A MA43120 A MA 43120A MA 43120 A MA43120 A MA 43120A
Authority
MA
Morocco
Prior art keywords
nitrogen containing
hiv replication
inhibitor activity
replication inhibitor
tricyclic derivative
Prior art date
Application number
MA043120A
Other languages
English (en)
Inventor
Toshiyuki Akiyama
Takashi Kawasuji
Akira Matsumura
Shuichi Sugiyama
Yoshinori Tamura
Yutaka Tomida
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of MA43120A publication Critical patent/MA43120A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MA043120A 2015-05-29 2016-05-27 Dérivé tricyclique contenant de l'azote présentant une activité inhibitrice de la réplication du vih MA43120A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2015109547 2015-05-29
JP2015170222 2015-08-31
JP2015223036 2015-11-13
JP2016054215 2016-03-17

Publications (1)

Publication Number Publication Date
MA43120A true MA43120A (fr) 2018-09-05

Family

ID=57442245

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043120A MA43120A (fr) 2015-05-29 2016-05-27 Dérivé tricyclique contenant de l'azote présentant une activité inhibitrice de la réplication du vih

Country Status (16)

Country Link
US (2) US10494380B2 (fr)
EP (1) EP3305789A4 (fr)
JP (2) JP6614585B2 (fr)
KR (1) KR20180011267A (fr)
CN (2) CN111138458A (fr)
AU (1) AU2016271762B2 (fr)
BR (1) BR112017025367A2 (fr)
CA (1) CA2987384A1 (fr)
HK (1) HK1253539A1 (fr)
IL (1) IL255580B (fr)
MA (1) MA43120A (fr)
MX (1) MX2017015256A (fr)
RU (1) RU2720145C2 (fr)
SG (1) SG11201709634QA (fr)
TW (1) TWI700284B (fr)
WO (1) WO2016194806A1 (fr)

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UA119848C2 (uk) 2013-03-15 2019-08-27 Інсайт Холдинґс Корпорейшн Трициклічні гетероцикли як інгібітори білків бет
JP2016523964A (ja) 2013-07-08 2016-08-12 インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ Ｂｅｔタンパク質阻害剤としての三環式複素環
WO2015081203A1 (fr) 2013-11-26 2015-06-04 Incyte Corporation Hétérocycles bicycliques servant d'inhibiteurs des protéines bet
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LT3134403T (lt) 2014-04-23 2020-05-11 Incyte Corporation 1h-pirolo[2,3-c]piridin-7(6h)-onai ir pirazolo[3,4-c]piridin-7(6h)-onai, kaip bet baltymų inhibitoriai
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US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms
CN112409493B (zh) * 2020-08-12 2022-09-30 浙江工业大学 一种重组融合酶及其在乙醛酸甲酯合成中的应用
CN114075212B (zh) * 2020-08-14 2023-05-12 江苏恒瑞医药股份有限公司 稠合三环类衍生物、其制备方法及其在医药上的应用

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Also Published As

Publication number Publication date
JP6614585B2 (ja) 2019-12-04
JP6797464B2 (ja) 2020-12-09
EP3305789A4 (fr) 2018-11-21
CN111138458A (zh) 2020-05-12
US10494380B2 (en) 2019-12-03
BR112017025367A2 (pt) 2018-08-07
SG11201709634QA (en) 2017-12-28
US20200055873A1 (en) 2020-02-20
IL255580A (en) 2018-01-31
MX2017015256A (es) 2018-02-19
TWI700284B (zh) 2020-08-01
CA2987384A1 (fr) 2016-12-08
CN107922423B (zh) 2020-10-27
KR20180011267A (ko) 2018-01-31
HK1253539A1 (zh) 2019-06-21
US10870661B2 (en) 2020-12-22
JPWO2016194806A1 (ja) 2018-03-22
US20180162876A1 (en) 2018-06-14
TW201706275A (zh) 2017-02-16
RU2017145082A (ru) 2019-07-01
IL255580B (en) 2020-11-30
RU2017145082A3 (fr) 2019-10-24
AU2016271762A1 (en) 2017-11-30
CN107922423A (zh) 2018-04-17
JP2020097568A (ja) 2020-06-25
RU2720145C2 (ru) 2020-04-24
EP3305789A1 (fr) 2018-04-11
AU2016271762B2 (en) 2020-01-23
WO2016194806A1 (fr) 2016-12-08

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