SG11201506977SA - Systems and methods for detection of cells using engineered transduction particles - Google Patents

Systems and methods for detection of cells using engineered transduction particles

Info

Publication number
SG11201506977SA
SG11201506977SA SG11201506977SA SG11201506977SA SG11201506977SA SG 11201506977S A SG11201506977S A SG 11201506977SA SG 11201506977S A SG11201506977S A SG 11201506977SA SG 11201506977S A SG11201506977S A SG 11201506977SA SG 11201506977S A SG11201506977S A SG 11201506977SA
Authority
SG
Singapore
Prior art keywords
cells
systems
detection
methods
transduction particles
Prior art date
Application number
SG11201506977SA
Other languages
English (en)
Inventor
Diego Ariel Rey
Shaunak Roy
Leonardo M Teixeira
Ryan C Griswold
Damian S Matthews
Kenneth G Olson
Bruce J Richardson
Rick V Stellmacher
Victor H Yee
Original Assignee
Geneweave Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geneweave Biosciences Inc filed Critical Geneweave Biosciences Inc
Publication of SG11201506977SA publication Critical patent/SG11201506977SA/en

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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  • Chemical & Material Sciences (AREA)
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  • Plasma & Fusion (AREA)
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  • Biomedical Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Plant Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
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SG11201506977SA 2013-03-13 2014-03-11 Systems and methods for detection of cells using engineered transduction particles SG11201506977SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361779177P 2013-03-13 2013-03-13
US13/802,461 US9481903B2 (en) 2013-03-13 2013-03-13 Systems and methods for detection of cells using engineered transduction particles
PCT/US2014/023422 WO2014164768A1 (en) 2013-03-13 2014-03-11 Systems and methods for detection of cells using engineered transduction particles

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SG11201506977SA true SG11201506977SA (en) 2015-10-29

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Country Status (15)

Country Link
US (6) US9481903B2 (ko)
EP (3) EP3401680B1 (ko)
JP (3) JP6524057B2 (ko)
KR (3) KR102060220B1 (ko)
CN (2) CN105209915B (ko)
AU (3) AU2014249022C1 (ko)
BR (1) BR112015022322A2 (ko)
CA (1) CA2903771C (ko)
ES (2) ES2835228T3 (ko)
HK (1) HK1217539A1 (ko)
MX (1) MX365093B (ko)
NZ (2) NZ750646A (ko)
RU (1) RU2666926C2 (ko)
SG (3) SG11201506977SA (ko)
WO (1) WO2014164768A1 (ko)

Families Citing this family (54)

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Publication number Priority date Publication date Assignee Title
US9816131B2 (en) * 2010-08-02 2017-11-14 Dxna Llc Pressurizable cartridge for polymerase chain reactions
EP3699592A1 (en) 2013-03-13 2020-08-26 Geneweave Biosciences Inc. Non-replicative transduction particles and transduction particle-based reporter systems
US9481903B2 (en) 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
US9540675B2 (en) 2013-10-29 2017-01-10 GeneWeave Biosciences, Inc. Reagent cartridge and methods for detection of cells
FR3019895B1 (fr) * 2014-04-10 2016-05-27 Gilson Sas Systeme de pipetage multicanaux comprenant deux chambres d'aspiration imbriquees l'une dans l'autre
DK3134553T3 (da) 2014-04-24 2019-11-18 Lucira Health Inc Kolorimetrisk detektering af nukleinsyreamplifikation
JP6787794B2 (ja) 2014-06-13 2020-11-18 ジーンウィーブ バイオサイエンシズ，インコーポレイティド 細胞の増殖非依存的検出
TW201614073A (en) 2014-08-25 2016-04-16 Geneweave Biosciences Inc Non-replicative transduction particles and transduction particle-based reporter systems
WO2016089477A1 (en) * 2014-10-16 2016-06-09 Cepheid Biosecurity screening system and method
US9879328B2 (en) 2014-11-21 2018-01-30 GeneWeave Biosciences, Inc. Mechanisms of antimicrobial susceptibility
US10227661B2 (en) 2014-11-21 2019-03-12 GeneWeave Biosciences, Inc. Sequence-specific detection and phenotype determination
US20160238627A1 (en) 2015-02-13 2016-08-18 Abbott Laboratories Decapping and capping apparatus, systems and methods for use in diagnostic analyzers
CN113941381A (zh) 2015-02-20 2022-01-18 文塔纳医疗系统公司 用于储存和运输浸入在流体中的组织样本的组件
US10351893B2 (en) * 2015-10-05 2019-07-16 GeneWeave Biosciences, Inc. Reagent cartridge for detection of cells
IL242807A0 (en) * 2015-11-26 2016-04-21 Novamed Ltd Test facility
EP3178557B1 (en) * 2015-12-11 2018-11-28 Biotage AB Device for flow control
US10718003B2 (en) 2015-12-31 2020-07-21 Roche Molecular Systems, Inc. Detecting an analyte in a flash and glow reaction
WO2017160840A1 (en) 2016-03-14 2017-09-21 Diassess Inc. Selectively vented biological assay devices and associated methods
JP6937774B2 (ja) 2016-03-14 2021-09-22 ルシラ ヘルス インコーポレイテッド 生物学的アッセイを実行するためのシステムおよび方法
AU2017232342B2 (en) 2016-03-14 2022-04-21 Pfizer Inc. Devices and methods for biological assay sample preparation and delivery
WO2017172645A2 (en) * 2016-03-28 2017-10-05 The Charles Stark Draper Laboratory, Inc. Bacteriophage engineering methods
US20170336397A1 (en) 2016-05-19 2017-11-23 Roche Molecular Systems, Inc. RFID Detection Systems And Methods
US20170336428A1 (en) 2016-05-19 2017-11-23 Roche Molecular Systems, Inc. RFID Tracking Systems And Methods
US11149319B2 (en) * 2016-12-20 2021-10-19 Roche Molecular Systems, Inc. Systems and methods for detecting cells using engineered transduction particles
RU2018134774A (ru) * 2016-12-28 2021-01-29 КАБУСИКИ КАЙСЯ Мираи Дженомикс Устройство для анализа
JP2020513764A (ja) 2016-12-30 2020-05-21 クイデル コーポレーション ファージ媒介性イムノアッセイ及び抗生物質又はプロバイオティック薬剤に対する細菌の感受性を決定するための方法
US10334984B2 (en) 2017-02-27 2019-07-02 iYukti LLC Apparatus and methods for making bread
GB201703383D0 (en) 2017-03-02 2017-04-19 Gargle Tech Ltd Testing for particulates
US10520498B2 (en) 2017-03-14 2019-12-31 Becton, Dickinson And Company Devices and techniques for oral fluid collection and seroprotection testing
US11080848B2 (en) 2017-04-06 2021-08-03 Lucira Health, Inc. Image-based disease diagnostics using a mobile device
US11077444B2 (en) 2017-05-23 2021-08-03 Roche Molecular Systems, Inc. Packaging for a molecular diagnostic cartridge
US10549275B2 (en) 2017-09-14 2020-02-04 Lucira Health, Inc. Multiplexed biological assay device with electronic readout
CN209400538U (zh) 2017-09-21 2019-09-17 贝克顿·迪金森公司 引导从表面收集有害污染物样品的模板和包括其的系统
CN209559735U (zh) 2017-09-21 2019-10-29 贝克顿·迪金森公司 用于引导收集有害污染物样本的系统
AU2018337650A1 (en) 2017-09-21 2020-04-09 Becton, Dickinson And Company High dynamic range assays in hazardous contaminant testing
CN111108380B (zh) 2017-09-21 2022-11-01 贝克顿·迪金森公司 危险污染物收集试剂盒和快速测试
AU2018337036B2 (en) 2017-09-21 2023-07-06 Becton, Dickinson And Company Augmented reality devices for hazardous contaminant testing
WO2019060269A1 (en) * 2017-09-21 2019-03-28 Becton, Dickinson And Company KIT FOR COLLECTING HAZARDOUS CONTAMINANTS AND RAPID ANALYSIS
EP3684945A4 (en) 2017-09-21 2021-09-22 Becton, Dickinson and Company SAMPLING SYSTEMS AND METHODS FOR SAMPLING HAZARDOUS CONTAMINANTS WITH HIGH EFFICIENCY
US11008602B2 (en) 2017-12-20 2021-05-18 Roche Molecular Systems, Inc. Non-replicative transduction particles and transduction particle-based reporter systems
KR102504987B1 (ko) * 2018-04-10 2023-02-28 엠쥐아이 테크 컴퍼니 엘티디. 형광 이미지 정합 방법, 유전자 시퀀서 및 시스템, 저장 매체
US11680877B2 (en) 2018-09-05 2023-06-20 Hero Scientific Ltd. Testing for particulates
US10968491B2 (en) 2018-12-05 2021-04-06 GeneWeave Biosciences, Inc. Growth-independent detection of cells
USD910200S1 (en) 2018-12-21 2021-02-09 Lucira Health, Inc. Test tube
EP3902927A1 (en) * 2018-12-29 2021-11-03 F. Hoffmann-La Roche AG Use of sideromycins to limit cross-reactivity and improve bacterial identification in antibiotic susceptibility assays
AU2020215639A1 (en) 2019-01-28 2021-08-05 Becton, Dickinson And Company Hazardous contaminant collection device with integrated swab and test device
US11660592B2 (en) 2020-02-14 2023-05-30 DeNovix, Inc. Dynamic broad volumetric range pipette
WO2021226145A1 (en) * 2020-05-04 2021-11-11 Biotex, Inc. Methods and devices for pathogen detection
USD953561S1 (en) 2020-05-05 2022-05-31 Lucira Health, Inc. Diagnostic device with LED display
USD962470S1 (en) 2020-06-03 2022-08-30 Lucira Health, Inc. Assay device with LCD display
US20220020481A1 (en) 2020-07-20 2022-01-20 Abbott Laboratories Digital pass verification systems and methods
WO2022149135A2 (en) 2021-01-06 2022-07-14 Hero Scientific Ltd. Filtration sampling devices
KR20220107586A (ko) 2021-01-25 2022-08-02 금오공과대학교 산학협력단 전기신호를 이용한 세포수 검출장치 및 이를 이용한 검출방법
KR20240035596A (ko) * 2021-08-31 2024-03-15 주식회사 씨젠 검체 수집 장치 및 검체 수집 방법

Family Cites Families (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE628679A (ko) 1962-02-28
US3826574A (en) 1973-02-12 1974-07-30 Continental Distributors Nephelometer
US4057148A (en) 1974-06-25 1977-11-08 G. D. Searle & Co. Multiple sample support assembly and apparatus for facilitating radioimmunoassays and the like
GB1571466A (en) 1976-12-14 1980-07-16 Univ California Assay mehtod
CA1277931C (en) 1984-06-05 1990-12-18 Shimon Ulitzur Detection and/or identification of microorganisms in a test sample usingbioluminescence or other exogenous genetically-introduced marker
US4861709A (en) 1985-05-31 1989-08-29 Technicon Research A.G. Detection and/or identification of microorganisms in a test sample using bioluminescence or other exogenous genetically-introduced marker
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
DE3540823C1 (de) 1985-11-16 1986-10-02 Laboratorium Prof. Dr. Rudolf Berthold, 7547 Wildbad Fotometrische Messstation
DE3751516T2 (de) 1986-04-30 1996-02-15 Igen Inc Elektrochemilumineszenz-testverfahren.
EP0274527B1 (en) 1986-07-22 1994-05-04 Boyce Thompson Institute For Plant Research, Inc. Use of bacterial luciferase structural genes for cloning and monitoring gene expression in microorganisms and for tagging and identification of genetically engineered organisms
US5221623A (en) 1986-07-22 1993-06-22 Boyce Thompson Institute For Plant Research, Inc. Use of bacterial luciferase structural genes for cloning and monitoring gene expression in microorganisms and for tagging and identification of genetically engineered organisms
US5128104A (en) 1987-04-27 1992-07-07 Murphy Harold R Cuvette for automated testing machine
JP2944694B2 (ja) * 1988-10-04 1999-09-06 ディーエヌエー プラント テクノロジー コーポレイション 検出可能な表現型のファージ形質導入による細菌の検出
FR2641793B1 (fr) 1988-12-26 1993-10-01 Setratech Procede de recombinaison in vivo de sequences d'adn presentant des mesappariements de bases
US5139745A (en) 1990-03-30 1992-08-18 Block Medical, Inc. Luminometer
GB9017443D0 (en) 1990-08-09 1990-09-26 Amersham Int Plc Reporter bacteria for rapid microbial detection
US5188455A (en) 1990-11-13 1993-02-23 The Pennsylvania Research Corporation Apparatus for remote mixing of fluids
US5086233A (en) 1991-01-22 1992-02-04 Dynatech Corporation Luminometers with sample container displacement controlled by ramped abutment
US5252479A (en) 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
US6300061B1 (en) 1992-02-07 2001-10-09 Albert Einstein College Of Medicine Of Yeshiva University Mycobacterial species-specific reporter mycobacteriophages
US5242660A (en) 1992-02-28 1993-09-07 Paul Hsei Sample preparation device
US5364591A (en) 1992-06-01 1994-11-15 Eastman Kodak Company Device for moving a target-bearing solid through a liquid for detection while being contained
JPH0634546A (ja) 1992-07-17 1994-02-08 Tosoh Corp 蛍光検出器
JP2936973B2 (ja) * 1993-09-17 1999-08-23 東洋紡績株式会社 発光測定装置
AU687363B2 (en) 1993-03-19 1998-02-26 Ciba Corning Diagnostics Corp. Luminometer
US5494646A (en) 1993-04-14 1996-02-27 Seymour; Eugene H. Sampling device and sample adequacy system
WO1994025572A1 (en) 1993-04-29 1994-11-10 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Mycobacterial species-specific reporter mycobacteriophages
GB2281966B (en) 1993-09-07 1997-06-04 Biotrace Ltd Bio-luminescence monitoring method
US5645801A (en) 1993-10-21 1997-07-08 Abbott Laboratories Device and method for amplifying and detecting target nucleic acids
DE4423935C2 (de) 1994-07-07 1998-02-05 Deutsche Forsch Luft Raumfahrt Küvette zur mikroskopischen oder makroskopischen Beobachtung einer biologischen Probe
JP2675532B2 (ja) 1994-12-20 1997-11-12 株式会社バイオセンサー研究所 化学発光測定装置
US5656424A (en) 1995-02-15 1997-08-12 Albert Einstein College Of Medicine, A Division Of Yeshiva University Identification of mycobacterium tuberculosis complex species
US5476768A (en) 1995-03-10 1995-12-19 Becton, Dickinson And Company Mycobacteriophage DSGA specific for the mycobacterium tuberculosis complex
DE19517940A1 (de) 1995-05-18 1996-11-21 Merck Patent Gmbh Nachweis von Listerien mittels rekombinanter Bakteriophagen
CA2196793A1 (en) 1995-06-07 1996-12-19 Hugh V. Cottingham Device and method for phage-based antibiotic susceptibility testing
US5730938A (en) 1995-08-09 1998-03-24 Bio-Chem Laboratory Systems, Inc. Chemistry analyzer
US5814022A (en) 1996-02-06 1998-09-29 Plasmaseal Llc Method and apparatus for applying tissue sealant
US5939262A (en) 1996-07-03 1999-08-17 Ambion, Inc. Ribonuclease resistant RNA preparation and utilization
US5677124A (en) 1996-07-03 1997-10-14 Ambion, Inc. Ribonuclease resistant viral RNA standards
US5905029A (en) 1997-02-19 1999-05-18 Fritz Berthold Method for rapid hygiene testing
US5917592A (en) * 1997-02-28 1999-06-29 Charm Sciences, Inc. Photometer, and test sample holder for use therein, method and system
US6410275B1 (en) 1997-05-02 2002-06-25 Biomerieux, Inc. Disposable test devices for performing nucleic acid amplification reactions
US5989499A (en) 1997-05-02 1999-11-23 Biomerieux, Inc. Dual chamber disposable reaction vessel for amplification reactions
SE9702005D0 (sv) 1997-05-28 1997-05-28 Alphahelix Ab New reaction vessel and method for its use
US6326208B1 (en) 1997-07-17 2001-12-04 Synermed International Inc. Assay for total and direct bilirubin
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
WO1999045354A2 (en) * 1998-03-02 1999-09-10 Biosensing Technologies Ltd. Luminescent microbe assay
EP1031630B1 (en) 1999-02-22 2004-10-20 Matsushita Electric Industrial Co., Ltd. Method for detecting bacteria
US6818185B1 (en) 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
US6271034B1 (en) 1999-07-08 2001-08-07 Albert Einstein College Of Medicine Of Yeshiva University One step allelic exchange in mycobacteria using in vitro generated conditional transducing phages
US6737266B1 (en) 1999-10-01 2004-05-18 3M Innovative Properties Company Devices and methods for microorganism detection
US7160511B2 (en) 2000-02-18 2007-01-09 Olympus Corporation Liquid pipetting apparatus and micro array manufacturing apparatus
US6548018B2 (en) * 2000-03-31 2003-04-15 Neogen Corporation Apparatus for chemiluminescent assays
JP2001337039A (ja) * 2000-05-26 2001-12-07 Dkk Toa Corp 発光検出装置
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
GB0108830D0 (en) 2001-04-09 2001-05-30 Univ Nottingham Controlling DNA packaging
ATE398775T1 (de) * 2001-05-09 2008-07-15 Axis Shield Asa Testvorrichtung
US6544729B2 (en) 2001-07-20 2003-04-08 University Of Tennessee Bioluminescent biosensor device
JP4849772B2 (ja) 2001-09-27 2012-01-11 ガンガゲン インコーポレーティッド 免疫原性が低いリシン欠損バクテリオファージ
US20030148335A1 (en) 2001-10-10 2003-08-07 Li Shen Detecting targets by unique identifier nucleotide tags
EP1438252A1 (en) 2001-10-19 2004-07-21 MonoGen, Inc. Container uncapping apparatus and method
WO2003060066A2 (en) 2001-11-07 2003-07-24 Musc Foundation For Research Development Nucleic acid delivery and expression
AU2002357107B2 (en) 2001-12-06 2008-01-10 Biocontrol Systems, Inc. Sample collection and testing system
US20030148536A1 (en) 2002-02-04 2003-08-07 Chi-Wang Liang Chemiluminescence analyzer
US6902704B2 (en) * 2002-02-28 2005-06-07 Equistar Chemicals, L.P Injection pump assembly for a combinatorial reactor and related method
US8216780B2 (en) 2002-04-12 2012-07-10 Microphage (Tm) Incorporated Method for enhanced sensitivity in bacteriophage-based diagnostic assays
DE60332740D1 (de) 2002-04-12 2010-07-08 Colorado School Of Mines Golde Verfahren zum nachweis geringer konzentrationen eines zielbakteriums unter verwendung von phagen zur infizierung von zielbakterienzellen
US20050003346A1 (en) 2002-04-12 2005-01-06 Colorado School Of Mines Apparatus and method for detecting microscopic living organisms using bacteriophage
JP2005532072A (ja) 2002-07-10 2005-10-27 マサチューセッツ・インスティテュート・オブ・テクノロジー サンプルから核酸を単離するための装置および方法
SE521478C2 (sv) 2002-11-14 2003-11-04 Magnetic Biosolutions Sweden A Pipetteringsapparat
US7238520B2 (en) * 2002-12-04 2007-07-03 Smiths Detection Inc. PCR sample preparation holder and method
US7125727B2 (en) 2003-01-29 2006-10-24 Protedyne Corporation Sample handling tool with piezoelectric actuator
DE10319045A1 (de) * 2003-04-25 2004-12-09 november Aktiengesellschaft Gesellschaft für Molekulare Medizin Vorrichtung und Verfahren zur Aufbereitung Biopolymerhaltiger Flüssigkeiten
FI20030867A (fi) 2003-06-10 2004-12-11 Wallac Oy Optinen mittausmenetelmä ja laboratoriomittauslaite
EP2407243B1 (en) 2003-07-31 2020-04-22 Handylab, Inc. Multilayered microfluidic device
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
CA2541941C (en) 2003-10-06 2015-05-26 Gangagen, Inc. Anti-bacterial phage tail compositions and uses thereof
FR2860731B1 (fr) 2003-10-14 2006-01-21 Maxmat S A Appareil de mixage d'un analyseur chimique ou biochimique avec entrainement pendulaire d'une pipette
DE212004000061U1 (de) 2003-11-14 2006-09-21 Oakville Hong Kong Co., Ltd. Schnelle Probenanalyse und Speichervorrichtungen
DE102004003434B4 (de) 2004-01-21 2006-06-08 Eppendorf Ag Pipettiervorrichtung mit einer Verdrängungseinrichtung und einer damit lösbar verbundenen Antriebseinrichtung
US20060257991A1 (en) 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
AU2005324479A1 (en) * 2004-04-07 2006-07-20 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Reporter plasmid phage packaging system for detection of bacteria
CN1980738A (zh) 2004-04-09 2007-06-13 科研智囊团有限公司 用于收集、储存和运输生物样本的设备和方法
US7674621B2 (en) 2004-05-21 2010-03-09 The United States Of America As Represented By The Department Of Health And Human Services Plasmids and phages for homologous recombination and methods of use
NZ551993A (en) 2004-07-06 2009-12-24 Mixis France Sa Generation of recombinant genes in a bacteriophage and a bacterial host cell.
US8182804B1 (en) 2004-09-13 2012-05-22 Trustees Of Boston University Engineered enzymatically active bacteriophages and methods of uses thereof
US20060068398A1 (en) 2004-09-24 2006-03-30 Cepheid Universal and target specific reagent beads for nucleic acid amplification
US7244612B2 (en) 2004-10-07 2007-07-17 University Of Wyoming Template reporter bacteriophage platform and multiple bacterial detection assays based thereon
KR100668310B1 (ko) 2004-11-01 2007-01-12 삼성전자주식회사 표적 세포 특이적 바이러스를 이용하여 표적 세포의존재를 검출하는 방법
RU2007120575A (ru) 2004-11-04 2008-12-10 Виз Энтерпрайсиз Многокамерная емкость и колпачок для нее
WO2006053588A1 (en) * 2004-11-17 2006-05-26 Agilent Technologies, Inc. Supply arrangement with supply reservoir element and fluidic device
US8057756B2 (en) 2005-01-28 2011-11-15 Parker-Hannifin Corporation Sampling probe, gripper and interface for laboratory sample management systems
EP2562266B1 (en) 2005-03-30 2016-02-24 Olympus Corporation Predetermined site luminescence measuring method, predetermined site luminescence measuring apparatus, expression amount measuring method, and measuring apparatus
WO2006105504A1 (en) 2005-03-31 2006-10-05 Microphage Incorporated Apparatus and method for detecting microorganisms using flagged bacteriophage
US20110097702A1 (en) 2005-03-31 2011-04-28 Voorhees Kent J Methods and compositions for in situ detection of microorganisms on a surface
EP1910824A4 (en) 2005-05-31 2012-11-21 Labnow Inc METHOD AND COMPOSITIONS RELATED TO THE PREPARATION AND USE OF A WHITE BLOOD IMAGE
CA2622439A1 (en) 2005-09-15 2007-03-29 Microphage Incorporated Method and apparatus for identification of microorganisms using bacteriophage
US20070072174A1 (en) 2005-09-28 2007-03-29 Sayler Gary S Bioreporter for detection of microbes
US7727473B2 (en) 2005-10-19 2010-06-01 Progentech Limited Cassette for sample preparation
US20070178450A1 (en) 2006-01-27 2007-08-02 Microphage (Tm) Incorporation Method and apparatus for determining level of microorganisms using bacteriophage
US20080003564A1 (en) 2006-02-14 2008-01-03 Iquum, Inc. Sample processing
WO2007115378A1 (en) 2006-04-11 2007-10-18 Minifab (Australia) Pty Ltd Microfluidic package housing
TW200817522A (en) 2006-06-09 2008-04-16 Bio Pur Ag A method for the detection of enzymatic reactions
US20070292397A1 (en) 2006-06-19 2007-12-20 Mcnulty Amy K Method for the detection and neutralization of bacteria
US8530178B2 (en) 2006-10-17 2013-09-10 Zymera, Inc. Hydrolase detection system with caged substrates
EP2087130A2 (en) 2006-10-31 2009-08-12 Microphage, Incorporated Method and apparatus for enhanced bacteriophage-based diagnostic assays by selective inhibition of potential cross-reactive organisms
CN101568636A (zh) 2006-11-02 2009-10-28 威腾技术公司 用于诊断性检测的模块
ITPD20060419A1 (it) 2006-11-13 2008-05-14 Federico Nalesso Dispositivo per il trattamento manutentivo di cateteri venosi centrali
US8355132B2 (en) 2007-04-06 2013-01-15 Qiagen Gaithersburg, Inc. Sample adequacy measurement system having a plurality of sample tubes and using turbidity light scattering techniques
EP2147125A4 (en) 2007-04-18 2010-12-15 Univ Cornell METHOD AND APPARATUS FOR DETECTING MICROORGANISM
JP5026849B2 (ja) * 2007-04-20 2012-09-19 株式会社日立製作所 化学発光計測装置
WO2008136769A1 (en) 2007-05-03 2008-11-13 Nanyang Technological University Online contaminant detection and removal system
JP5150856B2 (ja) 2007-06-15 2013-02-27 マイクロファージ・インコーポレーテッド バクテリオファージ増幅を向上させた微生物の検出方法
US20090155838A1 (en) 2007-11-28 2009-06-18 Smart Tube, Inc. Devices, systems and methods for the collection, stimulation, stabilization, and analysis of a biological sample
US8619257B2 (en) 2007-12-13 2013-12-31 Kimberley-Clark Worldwide, Inc. Recombinant bacteriophage for detection of nosocomial infection
US8153119B2 (en) 2007-12-18 2012-04-10 Trustees Of Boston University Engineered enzymatically active bacteriophage and methods for dispersing biofilms
US8329889B2 (en) 2008-02-15 2012-12-11 Trustees Of Boston University In vivo gene sensors
EP2276852B1 (en) 2008-05-14 2015-11-04 Guild Associates, Inc. Phage-mediated bioluminescent detection of yersinia pestis
CA3162577C (en) 2008-05-20 2023-09-26 University Health Network Device and method for fluorescence-based imaging and monitoring
US20120134975A1 (en) 2008-08-13 2012-05-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Biological targeting compositions and methods of using the same
JP2010107418A (ja) * 2008-10-31 2010-05-13 Optex Co Ltd 光測定方法および装置
KR101650017B1 (ko) 2008-12-16 2016-08-23 바이오메리욱스, 인코포레이티드. 고체 또는 반고체 배지 상의 미생물의 특성화 방법
US8645115B2 (en) 2008-12-22 2014-02-04 Trustees Of Boston University Modular nucleic acid-based circuits for counters, binary operations, memory and logic
JP2010151510A (ja) 2008-12-24 2010-07-08 Tdk Corp 液性測定装置
CN102405212B (zh) 2009-02-18 2016-01-27 康奈尔大学 在体内外使用的偶联识别/检测系统
EP2302029A1 (en) * 2009-09-29 2011-03-30 Fundacion Gaiker Portable enrichment, aliquoting, and testing device of microorganisms and toxins
US20110183314A1 (en) 2010-01-26 2011-07-28 Microphage Incorporated Bacteriophage-based microorganism diagnostic assay using speed or acceleration of bacteriophage reproduction
KR101882940B1 (ko) * 2010-02-23 2018-07-30 루미넥스 코포레이션 일체화된 샘플 제조, 반응 및 검출을 위한 장치 및 방법
WO2012037369A1 (en) 2010-09-15 2012-03-22 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
CA2834790C (en) 2011-05-04 2019-04-09 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
US20120288866A1 (en) 2011-05-11 2012-11-15 Genturadx, Inc. Systems and methods for producing an evaporation barrier in a reaction chamber
CN105861630B (zh) 2011-06-22 2020-01-21 国家医疗保健研究所 用于检测样品中存在产生碳青霉烯酶的细菌的方法
US9234227B2 (en) 2011-09-26 2016-01-12 Sample6 Technologies, Inc. Recombinant phage and methods
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
EP2863733B1 (en) 2012-06-20 2019-05-08 Advanced Animal Diagnostics, Inc. Sample collection and transfer assembly and related methods
EP3699592A1 (en) 2013-03-13 2020-08-26 Geneweave Biosciences Inc. Non-replicative transduction particles and transduction particle-based reporter systems
US9481903B2 (en) 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
US9540675B2 (en) 2013-10-29 2017-01-10 GeneWeave Biosciences, Inc. Reagent cartridge and methods for detection of cells

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