SG11201505241WA - Solid solution compositions and use in severe pain - Google Patents
Solid solution compositions and use in severe painInfo
- Publication number
- SG11201505241WA SG11201505241WA SG11201505241WA SG11201505241WA SG11201505241WA SG 11201505241W A SG11201505241W A SG 11201505241WA SG 11201505241W A SG11201505241W A SG 11201505241WA SG 11201505241W A SG11201505241W A SG 11201505241WA SG 11201505241W A SG11201505241W A SG 11201505241WA
- Authority
- SG
- Singapore
- Prior art keywords
- solid solution
- severe pain
- solution compositions
- compositions
- pain
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 239000006104 solid solution Substances 0.000 title 1
Classifications
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
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US10307388B2 (en) * | 2016-12-29 | 2019-06-04 | The United States Of America As Represented By The Secretary Of The Navy | Compositions and methods for diagnosis and treatment of inflammation |
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EP3793560A4 (de) * | 2018-05-16 | 2022-03-23 | Epitracker, Inc. | Zusammensetzungen und verfahren zur diagnose und behandlung von alterungsbedingten zuständen |
JP2021525249A (ja) | 2018-05-23 | 2021-09-24 | エピトラッカー インコーポレイテッドEpitracker, Inc. | 加齢及び長期性の質に関連する状態の診断及び治療のための組成物及び方法 |
CN108653273A (zh) * | 2018-07-13 | 2018-10-16 | 昆明医科大学第附属医院 | 青蒿素类化合物作为制备治疗贝赫切特病药物的应用 |
CN110251549B (zh) * | 2019-06-24 | 2021-12-03 | 浙江省肿瘤医院 | 淫羊藿总黄酮提取物在制备防治桥本甲状腺炎的药物中的应用 |
CN114007590A (zh) * | 2019-06-28 | 2022-02-01 | 江苏恒瑞医药股份有限公司 | 一种缓释脂质组合物及其制备方法 |
CN113727708A (zh) * | 2019-07-21 | 2021-11-30 | Scf制药股份有限公司 | 具有多不饱和脂肪酸甘油单酯的大麻素组合物、其方法和用途 |
US20230057782A1 (en) * | 2020-02-03 | 2023-02-23 | Curemast, Inc. | Compositions and methods of use thereof for treatment of mastitis |
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Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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US6063768A (en) | 1997-09-04 | 2000-05-16 | First; Eric R. | Application of botulinum toxin to the management of neurogenic inflammatory disorders |
GB2331458B (en) * | 1997-11-21 | 2002-07-31 | Gursharan Singh Moonga | Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
WO2000067728A2 (de) * | 1999-05-07 | 2000-11-16 | Pharmasol Gmbh | Lipidpartikel auf der basis von mischungen von flüssigen und festen lipiden und verfahren zu ihrer herstellung |
US8663692B1 (en) * | 1999-05-07 | 2014-03-04 | Pharmasol Gmbh | Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same |
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CN1174741C (zh) * | 1999-09-21 | 2004-11-10 | Rtp药品公司 | 生物活性物质的表面改性微粒组合物 |
US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
US20060034937A1 (en) * | 1999-11-23 | 2006-02-16 | Mahesh Patel | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
FR2805761B1 (fr) * | 2000-03-02 | 2002-08-30 | Mainelab | Nanocapsules lipidiques, procede de preparation et utilisation comme medicament |
US6455067B1 (en) * | 2000-05-24 | 2002-09-24 | Sang-A Pharmaceutical Co., Ltd. | Transdermal patch for nonsteroidal antiinflammatory drug(s) |
JP3763567B2 (ja) * | 2001-01-19 | 2006-04-05 | 株式会社資生堂 | 化粧料 |
US20030105141A1 (en) * | 2001-04-17 | 2003-06-05 | Ping Gao | Finely self-emulsifiable pharmaceutical composition |
CA2533101A1 (en) * | 2003-07-31 | 2005-02-03 | Pharmacia & Upjohn Company Llc | Dispersible formulation of an anti-inflammatory agent |
KR20060085686A (ko) * | 2003-10-10 | 2006-07-27 | 라이프사이클 파마 에이/에스 | 피브레이트를 포함하는 고형 제제 |
RU2006120408A (ru) * | 2003-11-13 | 2007-12-20 | Комбинаторкс, Инкорпорейтед (Us) | Способы и реагенты для лечения воспалительных нарушений |
EP1694305B1 (de) * | 2003-12-01 | 2019-10-16 | Recordati Ireland Limited | Pharmazeutische zusammensetzungen mit lercanidipin |
US20070196396A1 (en) * | 2004-02-11 | 2007-08-23 | Rubicon Research Private Limited | Controlled release pharmaceutical compositions with improved bioavailability |
PL1729797T3 (pl) * | 2004-03-22 | 2009-02-27 | Abbott Laboratories Gmbh | Doustne kompozycje farmaceutyczne produktów zawierających lipazę, a zwłaszcza pankreatynę, zawierające środki powierzchniowo czynne |
RU2007123366A (ru) * | 2004-11-24 | 2008-12-27 | Мерк Энд Ко. | Жидкие и полутвердые фармацевтические препаративные формы для перорального введения замещенного амида |
US20060138059A1 (en) | 2004-12-28 | 2006-06-29 | Vair Larry L Jr | Corona-treated polypropylene liquid filtration media |
WO2006115463A1 (en) * | 2005-04-28 | 2006-11-02 | Galenica Technology Ab | Pharmaceutical dosage forms comprising a lipid phase |
GB0610867D0 (en) * | 2006-06-01 | 2006-07-12 | Syntaxin Ltd | Treatment of pain |
GB0704846D0 (en) * | 2007-03-13 | 2007-04-18 | Futura Medical Dev Ltd | Topical pharmaceutical formulation |
RU2353349C2 (ru) * | 2007-04-18 | 2009-04-27 | Общество с ограниченной ответственностью "Фармацевтические технологии" | Средство для лечения болезней суставов |
CN101129335B (zh) * | 2007-07-17 | 2010-09-22 | 浙江大学 | 一种纳米结构脂质载体给药系统的用途 |
EP2310371B1 (de) | 2008-05-26 | 2013-05-15 | Genfit | Ppar-agonistenverbindungen und zubereitung und anwendungen davon zur behandlung von diabetes und/oder dyslipidämie |
GB201018289D0 (en) * | 2010-10-29 | 2010-12-15 | Biocopea Ltd | Treatment of respiratory disorders |
MX346224B (es) * | 2011-02-04 | 2017-03-10 | Biocopea Ltd | Composiciones y metodos para el tratamiento de inflamacion cronica y enfermedades inflamatorias. |
EP2688560A2 (de) * | 2011-03-24 | 2014-01-29 | Leo Pharma A/S | Zusammensetzung aus lipidnanopartikeln und einem kortikosteroid oder vitamin-d-derivat |
CN102793628B (zh) * | 2012-08-23 | 2014-07-02 | 东华大学 | 用于化妆品的液-固混合脂质纳米缓释系统及其制备方法 |
KR102252574B1 (ko) * | 2013-01-14 | 2021-05-17 | 인퍼스트 헬스케어 리미티드 | 고용체 조성물들 및 만성염증에서의 이의 용도 |
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