EP3007720A4 - Zusammensetzungen mit einem gc-makrophagen-aktivierenden faktor und verwendungen davon - Google Patents

Zusammensetzungen mit einem gc-makrophagen-aktivierenden faktor und verwendungen davon

Info

Publication number
EP3007720A4
EP3007720A4 EP14810595.0A EP14810595A EP3007720A4 EP 3007720 A4 EP3007720 A4 EP 3007720A4 EP 14810595 A EP14810595 A EP 14810595A EP 3007720 A4 EP3007720 A4 EP 3007720A4
Authority
EP
European Patent Office
Prior art keywords
compositions
activating factor
macrophage activating
macrophage
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14810595.0A
Other languages
English (en)
French (fr)
Other versions
EP3007720A1 (de
Inventor
Ilana Margalit
Michal Shahar
Sveta Lifshits
Aya Spitzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EFRANAT Ltd
Original Assignee
EFRANAT Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EFRANAT Ltd filed Critical EFRANAT Ltd
Publication of EP3007720A1 publication Critical patent/EP3007720A1/de
Publication of EP3007720A4 publication Critical patent/EP3007720A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP14810595.0A 2013-06-09 2014-06-09 Zusammensetzungen mit einem gc-makrophagen-aktivierenden faktor und verwendungen davon Withdrawn EP3007720A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361832867P 2013-06-09 2013-06-09
PCT/IL2014/050516 WO2014199373A1 (en) 2013-06-09 2014-06-09 Compositions comprising gc- macrophage activating factor and uses thereof

Publications (2)

Publication Number Publication Date
EP3007720A1 EP3007720A1 (de) 2016-04-20
EP3007720A4 true EP3007720A4 (de) 2016-12-07

Family

ID=52021738

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14810595.0A Withdrawn EP3007720A4 (de) 2013-06-09 2014-06-09 Zusammensetzungen mit einem gc-makrophagen-aktivierenden faktor und verwendungen davon

Country Status (7)

Country Link
US (1) US20160120946A1 (de)
EP (1) EP3007720A4 (de)
JP (1) JP2016520646A (de)
CN (1) CN105530950A (de)
AU (1) AU2014279627A1 (de)
CA (1) CA2913115A1 (de)
WO (1) WO2014199373A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180078613A1 (en) * 2015-04-07 2018-03-22 Efranat Ltd. Macrophage activating factor for treating benign or precancerous papillomas
WO2016162867A1 (en) * 2015-04-08 2016-10-13 Efranat Ltd. Combination therapy of macrophage activating factor and pd-1 signaling inhibitors
JP6555738B2 (ja) * 2015-05-20 2019-08-07 再生ファーマ株式会社 疲労を伴う疾患の予防改善剤
TW201722984A (zh) * 2015-11-05 2017-07-01 Glatt Ingtech Gmbh 用於生產含ＧｃＭＡＦ配方之乾燥劑型之方法及裝置
US20210198307A1 (en) * 2017-12-15 2021-07-01 Foundation For Biomedical Research And Innovation At Kobe Method for producing active gcmaf
AT521556A1 (de) * 2018-07-24 2020-02-15 Hg Pharma Gmbh Vitamin D bindendes Protein
RU2717218C1 (ru) * 2019-08-07 2020-03-18 Зайцева Инга Николаевна Способ торможения роста подкожного трансплантата экспериментальной глиобластомы человека u-87, перевитого иммунодефицитным мышам nu/j
CN112618482A (zh) * 2019-09-24 2021-04-09 江苏恒瑞医药股份有限公司 新型蛋白制剂

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712104A (en) * 1995-06-07 1998-01-27 Yamamoto; Nobuto Diagnostic and prognostic elisa assays of serum or plasma α-N-acetylgalactosaminidase for cancer
WO2004060396A2 (en) * 2002-12-27 2004-07-22 Chiron Corporation Immunogenic compositions containing phospholpid

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1234383A (en) * 1982-03-17 1983-09-22 Inter-Yeda Ltd. Interferon stabilised with polyvinyl-pyrrolidone
DE3603444A1 (de) * 1986-02-05 1987-08-06 Thomae Gmbh Dr K Pharmazeutische zubereitungsformen zur stabilisierung von interferon alpha
US5177002A (en) * 1989-11-20 1993-01-05 Nobuto Yamamoto In vitro enzymatic conversion of glycosylated human vitamin D binding protein to a potent macrophage activating factor
US5177001A (en) * 1989-11-20 1993-01-05 Nobuto Yamamoto In vitro enzymatic conversion of glycosylated mammalian vitamin D-binding protein to a potent macrophage activating factor
US6806355B2 (en) * 2001-08-14 2004-10-19 Statens Serum Institut Purification process for large scale production of Gc-globulin, the Gc-globulin produced hereby, a use of Gc.globulin and a Gc-globulin medicinal product
DE60237841D1 (de) * 2001-11-13 2010-11-11 Genentech Inc Zusammensetzungen basierend auf APO2-Ligand/ TRAIL und ihre Verwendung
SI21257A (sl) * 2002-07-17 2004-02-29 LEK farmacevtska dru�ba d.d. Stabilni farmacevtski pripravek, ki vsebuje eritropoietin
US8367054B2 (en) * 2006-11-24 2013-02-05 Cadila Healthcare Limited Formulations of PEG-interferon alpha conjugates
WO2012137199A1 (en) * 2011-04-07 2012-10-11 Efranat Ltd. Macrophage activating factor for pharmaceutical compositions
EP2561879A1 (de) * 2011-08-23 2013-02-27 Protea Biopharma N.V. Makrophagenaktivierungsfaktor zur Verwendung bei der Behandlung des chronischen Ermüdungssyndroms sowie Erkrankungen und Störungen im Zusammenhang mit dem chronischen Ermüdungssyndrom

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712104A (en) * 1995-06-07 1998-01-27 Yamamoto; Nobuto Diagnostic and prognostic elisa assays of serum or plasma α-N-acetylgalactosaminidase for cancer
WO2004060396A2 (en) * 2002-12-27 2004-07-22 Chiron Corporation Immunogenic compositions containing phospholpid

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NOBUTO YAMAMOTO ET AL: "Immunotherapy for Prostate Cancer with Gc Protein-Derived Macrophage-Activating Factor, GcMAF", TRANSLATIONAL ONCOLOGY, NEOPLASIA PRESS, UNITED STATES, vol. 1, no. 2, 1 June 2008 (2008-06-01), pages 65 - 72, XP008154499, ISSN: 1944-7124, DOI: 10.1593/TLO.08106 *
See also references of WO2014199373A1 *

Also Published As

Publication number Publication date
JP2016520646A (ja) 2016-07-14
WO2014199373A1 (en) 2014-12-18
US20160120946A1 (en) 2016-05-05
EP3007720A1 (de) 2016-04-20
CN105530950A (zh) 2016-04-27
CA2913115A1 (en) 2014-12-18
AU2014279627A1 (en) 2015-12-03

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