SG11201501683WA - Coated pharmaceutical composition containing regorafenib - Google Patents

Coated pharmaceutical composition containing regorafenib

Info

Publication number
SG11201501683WA
SG11201501683WA SG11201501683WA SG11201501683WA SG11201501683WA SG 11201501683W A SG11201501683W A SG 11201501683WA SG 11201501683W A SG11201501683W A SG 11201501683WA SG 11201501683W A SG11201501683W A SG 11201501683WA SG 11201501683W A SG11201501683W A SG 11201501683WA
Authority
SG
Singapore
Prior art keywords
pharmaceutical composition
composition containing
coated pharmaceutical
containing regorafenib
regorafenib
Prior art date
Application number
SG11201501683WA
Other languages
English (en)
Inventor
Dr Susanne Skrabs
Dr Adrian Funke
Dr Mayk Kresse
Dr Ulrich Oberdieck
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46963450&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201501683W(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of SG11201501683WA publication Critical patent/SG11201501683WA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11201501683WA 2012-09-06 2013-09-05 Coated pharmaceutical composition containing regorafenib SG11201501683WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12183331 2012-09-06
PCT/US2013/058257 WO2014039677A1 (en) 2012-09-06 2013-09-05 Coated pharmaceutical composition containing regorafenib

Publications (1)

Publication Number Publication Date
SG11201501683WA true SG11201501683WA (en) 2015-04-29

Family

ID=46963450

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201501683WA SG11201501683WA (en) 2012-09-06 2013-09-05 Coated pharmaceutical composition containing regorafenib

Country Status (43)

Country Link
US (1) US20140065212A1 (zh)
EP (2) EP3243508A1 (zh)
JP (1) JP6445436B2 (zh)
KR (1) KR102162036B1 (zh)
CN (5) CN116392484A (zh)
AP (1) AP2015008292A0 (zh)
AR (1) AR092439A1 (zh)
AU (1) AU2013312531B2 (zh)
BR (1) BR112015004936B1 (zh)
CA (1) CA2883767C (zh)
CL (1) CL2015000544A1 (zh)
CO (1) CO7310528A2 (zh)
CR (1) CR20150114A (zh)
CU (1) CU24244B1 (zh)
CY (1) CY1118839T1 (zh)
DK (1) DK2892507T3 (zh)
EA (1) EA027685B1 (zh)
ES (1) ES2623205T3 (zh)
GT (1) GT201500053A (zh)
HK (1) HK1214170A1 (zh)
HR (1) HRP20170620T1 (zh)
HU (1) HUE032758T2 (zh)
IL (1) IL237350B (zh)
IN (1) IN2015DN01673A (zh)
JO (1) JO3479B1 (zh)
LT (1) LT2892507T (zh)
MA (1) MA37888B1 (zh)
MX (1) MX359922B (zh)
MY (1) MY176135A (zh)
NZ (1) NZ705578A (zh)
PE (1) PE20151005A1 (zh)
PH (1) PH12015500460B1 (zh)
PL (1) PL2892507T3 (zh)
PT (1) PT2892507T (zh)
RS (1) RS56019B1 (zh)
SA (1) SA515360113B1 (zh)
SG (1) SG11201501683WA (zh)
SI (1) SI2892507T1 (zh)
TW (1) TWI640329B (zh)
UA (1) UA115994C2 (zh)
UY (1) UY35006A (zh)
WO (1) WO2014039677A1 (zh)
ZA (1) ZA201501394B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR081060A1 (es) 2010-04-15 2012-06-06 Bayer Schering Pharma Ag Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida
US20160220494A1 (en) * 2013-09-13 2016-08-04 Bayer Pharma Aktiengesellschaft Pharmaceutical compositions containing refametinib
CN104586808B (zh) * 2014-12-27 2017-08-18 北京元延医药科技股份有限公司 抗肿瘤药物组合物
CN105136956A (zh) * 2015-09-11 2015-12-09 江苏嘉逸医药有限公司 一种快速测定瑞戈非尼含量的方法
CN105267167A (zh) * 2015-09-11 2016-01-27 江苏嘉逸医药有限公司 一种瑞戈非尼口服固体药物组合物的制备方法
CN106880607A (zh) * 2015-12-15 2017-06-23 北大方正集团有限公司 一种含有瑞戈非尼的口腔崩解片及其制备方法
CN106880615A (zh) * 2015-12-15 2017-06-23 北大方正集团有限公司 一种瑞戈非尼的口服固体制剂及其制备方法
CN105496975B (zh) * 2015-12-17 2019-01-04 河南润弘制药股份有限公司 一种瑞戈非尼片剂及其制备方法
CN106913527A (zh) * 2015-12-28 2017-07-04 江苏先声药业有限公司 一种瑞戈非尼速释微丸及其制备方法
CN105879049B (zh) * 2016-05-13 2019-03-26 浙江大学 一种瑞戈非尼与β-环糊精的包合物及其制备方法
CN107661296A (zh) * 2016-07-27 2018-02-06 江苏先声药业有限公司 一种瑞戈非尼固体分散体及其制备方法
EP3630112B9 (en) 2017-06-02 2024-06-26 Bayer HealthCare LLC Combination of regorafenib and nivolumab for treating cancer
KR20210029775A (ko) * 2018-07-06 2021-03-16 아지오스 파마슈티컬스 아이엔씨. 이보시데닙 형태 및 약제학적 조성물
CN111053751A (zh) * 2018-10-16 2020-04-24 正大天晴药业集团股份有限公司 瑞戈非尼的缓释片剂及其制备方法
TWI799599B (zh) * 2019-06-06 2023-04-21 華納國際生物科技股份有限公司 醫藥或保健品自乳化固體分散組成物
EP3861989A1 (en) * 2020-02-07 2021-08-11 Bayer Aktiengesellschaft Pharmaceutical composition containing regorafenib and a stabilizing agent
CN112587485A (zh) * 2021-01-08 2021-04-02 湖南南新制药股份有限公司 一种药物固体分散体及其制备方法
CN113018274A (zh) * 2021-03-10 2021-06-25 药源生物科技（启东）有限公司 一种含羟丙甲纤维素的药物组合物及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003272504A1 (en) * 2002-09-20 2004-04-08 Andrx Labs Llc Multistage formulation containing a biguanide and thiazolidindione derivatives
CN1265793C (zh) * 2002-11-18 2006-07-26 杭州容立医药科技有限公司 左西替利嗪伪麻黄碱复方口服制剂及制备方法
UA84156C2 (ru) 2003-07-23 2008-09-25 Байер Фармасьютикалс Корпорейшн Фторозамещённая омега-карбоксиарилдифенилмочевина для лечения и профилактики болезней и состояний
MY191349A (en) 2004-08-27 2022-06-17 Bayer Pharmaceuticals Corp New pharmaceutical compositions for the treatment of hyper-proliferative disorders
EP1962842A1 (en) * 2005-12-15 2008-09-03 Bayer HealthCare AG Diaryl ureas for treating inflammatory skin, eye and/or ear diseases
AR062927A1 (es) 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
WO2008044111A1 (en) * 2006-10-13 2008-04-17 Pfizer Products Inc. Pharmaceutical formulation tablet
US20100179184A1 (en) * 2006-12-07 2010-07-15 Matthew John Moon Article of manufacture for prasugrel
US20100316711A1 (en) * 2007-10-25 2010-12-16 Bayer Yakuhin ,Ltd. Nifedipine containing opress coated tablet and method of preparing same
AR081060A1 (es) * 2010-04-15 2012-06-06 Bayer Schering Pharma Ag Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida
JP6055465B2 (ja) * 2011-05-20 2016-12-27 アストラゼネカ・ユーケイ・リミテッドＡｓｔｒａＺｅｎｅｃａ ＵＫ Ｌｉｍｉｔｅｄ ロスバスタチンカルシウムの医薬組成物

Also Published As

Publication number Publication date
KR20150048872A (ko) 2015-05-07
JO3479B1 (ar) 2020-07-05
MX2015002815A (es) 2015-05-15
CY1118839T1 (el) 2018-01-10
AR092439A1 (es) 2015-04-22
MA37888B1 (fr) 2019-08-30
RS56019B1 (sr) 2017-09-29
AU2013312531B2 (en) 2017-10-19
IN2015DN01673A (zh) 2015-07-03
ZA201501394B (en) 2016-07-27
UY35006A (es) 2014-03-31
EP3243508A1 (en) 2017-11-15
MY176135A (en) 2020-07-24
MA37888A1 (fr) 2018-07-31
JP6445436B2 (ja) 2018-12-26
SA515360113B1 (ar) 2016-08-10
UA115994C2 (uk) 2018-01-25
NZ705578A (en) 2017-10-27
GT201500053A (es) 2015-10-12
US20140065212A1 (en) 2014-03-06
TW201414510A (zh) 2014-04-16
AP2015008292A0 (en) 2015-02-28
AU2013312531A1 (en) 2015-03-12
CA2883767C (en) 2018-11-13
PH12015500460A1 (en) 2015-04-20
BR112015004936A2 (pt) 2017-07-04
ES2623205T3 (es) 2017-07-10
PH12015500460B1 (en) 2015-04-20
CA2883767A1 (en) 2014-03-13
EA201590520A1 (ru) 2015-10-30
SI2892507T1 (sl) 2017-08-31
CU24244B1 (es) 2017-02-02
HRP20170620T1 (hr) 2017-06-30
CN104902878A (zh) 2015-09-09
IL237350B (en) 2020-11-30
HK1214170A1 (zh) 2016-07-22
LT2892507T (lt) 2017-06-12
WO2014039677A1 (en) 2014-03-13
CO7310528A2 (es) 2015-06-30
HUE032758T2 (en) 2017-10-30
CN116392485A (zh) 2023-07-07
DK2892507T3 (en) 2017-05-01
PE20151005A1 (es) 2015-06-27
EP2892507B1 (en) 2017-02-01
EA027685B1 (ru) 2017-08-31
CU20150020A7 (es) 2015-05-28
IL237350A0 (en) 2015-04-30
JP2015527395A (ja) 2015-09-17
CR20150114A (es) 2015-05-11
CN116392484A (zh) 2023-07-07
MX359922B (es) 2018-10-16
BR112015004936B1 (pt) 2022-12-06
TWI640329B (zh) 2018-11-11
KR102162036B1 (ko) 2020-10-07
CL2015000544A1 (es) 2015-08-21
CN116392598A (zh) 2023-07-07
PT2892507T (pt) 2017-05-02
CN111249247A (zh) 2020-06-09
PL2892507T3 (pl) 2017-09-29
EP2892507A1 (en) 2015-07-15

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