CU24244B1 - Composición farmacéutica recubierta que contiene regorafenib - Google Patents
Composición farmacéutica recubierta que contiene regorafenibInfo
- Publication number
- CU24244B1 CU24244B1 CUP2015000020A CU20150020A CU24244B1 CU 24244 B1 CU24244 B1 CU 24244B1 CU P2015000020 A CUP2015000020 A CU P2015000020A CU 20150020 A CU20150020 A CU 20150020A CU 24244 B1 CU24244 B1 CU 24244B1
- Authority
- CU
- Cuba
- Prior art keywords
- pharmaceutical composition
- composition containing
- containing regorafenib
- covered
- regorafenib
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a una composición farmacéutica recubierta que contiene regorafenib de fórmula (I), ESPACIO PARA FORMULA I o un hidrato, farmacéuticamente aceptable del mismo, donde la composición está recubierta por un recubrimiento que comprende un polímero basado en alcohol polivinílico, útil para el tratamiento de trastornos hiperproliferativos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12183331 | 2012-09-06 | ||
| PCT/US2013/058257 WO2014039677A1 (en) | 2012-09-06 | 2013-09-05 | Coated pharmaceutical composition containing regorafenib |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20150020A7 CU20150020A7 (es) | 2015-05-28 |
| CU24244B1 true CU24244B1 (es) | 2017-02-02 |
Family
ID=46963450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2015000020A CU24244B1 (es) | 2012-09-06 | 2013-09-05 | Composición farmacéutica recubierta que contiene regorafenib |
Country Status (43)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR081060A1 (es) | 2010-04-15 | 2012-06-06 | Bayer Schering Pharma Ag | Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida |
| JP2016531151A (ja) * | 2013-09-13 | 2016-10-06 | バイエル ファーマ アクチエンゲゼルシャフト | レファメチニブを含有する医薬組成物 |
| CN104586808B (zh) * | 2014-12-27 | 2017-08-18 | 北京元延医药科技股份有限公司 | 抗肿瘤药物组合物 |
| CN105136956A (zh) * | 2015-09-11 | 2015-12-09 | 江苏嘉逸医药有限公司 | 一种快速测定瑞戈非尼含量的方法 |
| CN105267167A (zh) * | 2015-09-11 | 2016-01-27 | 江苏嘉逸医药有限公司 | 一种瑞戈非尼口服固体药物组合物的制备方法 |
| CN106880607A (zh) * | 2015-12-15 | 2017-06-23 | 北大方正集团有限公司 | 一种含有瑞戈非尼的口腔崩解片及其制备方法 |
| CN106880615A (zh) * | 2015-12-15 | 2017-06-23 | 北大方正集团有限公司 | 一种瑞戈非尼的口服固体制剂及其制备方法 |
| CN105496975B (zh) * | 2015-12-17 | 2019-01-04 | 河南润弘制药股份有限公司 | 一种瑞戈非尼片剂及其制备方法 |
| CN106913527A (zh) * | 2015-12-28 | 2017-07-04 | 江苏先声药业有限公司 | 一种瑞戈非尼速释微丸及其制备方法 |
| CN105879049B (zh) * | 2016-05-13 | 2019-03-26 | 浙江大学 | 一种瑞戈非尼与β-环糊精的包合物及其制备方法 |
| CN107661296A (zh) * | 2016-07-27 | 2018-02-06 | 江苏先声药业有限公司 | 一种瑞戈非尼固体分散体及其制备方法 |
| CA3244313A1 (en) * | 2017-06-02 | 2025-06-13 | Bayer Healthcare Llc | Combination of regorafenib and pd-1/pd-l1(2) inhibitors for treating cancer |
| BR112021000156A2 (pt) * | 2018-07-06 | 2021-04-06 | Agios Pharmaceuticals, Inc. | Formas de ivosidenib e composições farmacêuticas |
| CN111053751A (zh) * | 2018-10-16 | 2020-04-24 | 正大天晴药业集团股份有限公司 | 瑞戈非尼的缓释片剂及其制备方法 |
| TWI799599B (zh) * | 2019-06-06 | 2023-04-21 | 華納國際生物科技股份有限公司 | 醫藥或保健品自乳化固體分散組成物 |
| EP3861989A1 (en) * | 2020-02-07 | 2021-08-11 | Bayer Aktiengesellschaft | Pharmaceutical composition containing regorafenib and a stabilizing agent |
| CN112587485A (zh) * | 2021-01-08 | 2021-04-02 | 湖南南新制药股份有限公司 | 一种药物固体分散体及其制备方法 |
| CN113018274A (zh) * | 2021-03-10 | 2021-06-25 | 药源生物科技（启东）有限公司 | 一种含羟丙甲纤维素的药物组合物及其制备方法 |
| TR2023002707A2 (tr) * | 2023-03-10 | 2024-09-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Regorafenib içeren bir farmasötik bileşim. |
| WO2025242583A1 (en) | 2024-05-24 | 2025-11-27 | Bayer Consumer Care Ag | Novel formulation comprising elinzanetant in a solid dispersion |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003272504A1 (en) * | 2002-09-20 | 2004-04-08 | Andrx Labs Llc | Multistage formulation containing a biguanide and thiazolidindione derivatives |
| CN1265793C (zh) * | 2002-11-18 | 2006-07-26 | 杭州容立医药科技有限公司 | 左西替利嗪伪麻黄碱复方口服制剂及制备方法 |
| RS52625B (sr) | 2003-07-23 | 2013-06-28 | Bayer Healthcare Llc | Fluoro supstituisana omega-karboksiaril difenil urea za lečenje i prevenciju bolesti i stanja bolesti |
| MY191349A (en) * | 2004-08-27 | 2022-06-17 | Bayer Pharmaceuticals Corp | New pharmaceutical compositions for the treatment of hyper-proliferative disorders |
| JP2009519266A (ja) * | 2005-12-15 | 2009-05-14 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | 炎症性の皮膚、眼および／または耳疾患を処置するためのジアリールウレア類 |
| AR062927A1 (es) * | 2006-10-11 | 2008-12-17 | Bayer Healthcare Ag | 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada |
| WO2008044111A1 (en) * | 2006-10-13 | 2008-04-17 | Pfizer Products Inc. | Pharmaceutical formulation tablet |
| AU2007333302A1 (en) * | 2006-12-07 | 2008-06-19 | Eli Lilly And Company | An article comprising prasugrel |
| JP5351490B2 (ja) * | 2007-10-25 | 2013-11-27 | バイエル薬品株式会社 | ニフェジピン含有有核錠剤およびその製法 |
| AR081060A1 (es) * | 2010-04-15 | 2012-06-06 | Bayer Schering Pharma Ag | Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida |
| KR20200003219A (ko) * | 2011-05-20 | 2020-01-08 | 아스트라제네카 유케이 리미티드 | 로수바스타틴 칼슘의 약학 조성물 |
-
2013
- 2013-09-04 AR ARP130103145A patent/AR092439A1/es not_active Application Discontinuation
- 2013-09-04 UY UY0001035006A patent/UY35006A/es active IP Right Grant
- 2013-09-04 JO JOP/2013/0268A patent/JO3479B1/ar active
- 2013-09-05 EP EP13762967.1A patent/EP2892507B1/en active Active
- 2013-09-05 CN CN202310406916.6A patent/CN116392598A/zh active Pending
- 2013-09-05 EP EP17153541.2A patent/EP3243508A1/en not_active Withdrawn
- 2013-09-05 IN IN1673DEN2015 patent/IN2015DN01673A/en unknown
- 2013-09-05 HU HUE13762967A patent/HUE032758T2/en unknown
- 2013-09-05 BR BR112015004936-2A patent/BR112015004936B1/pt active IP Right Grant
- 2013-09-05 NZ NZ705578A patent/NZ705578A/en unknown
- 2013-09-05 AU AU2013312531A patent/AU2013312531B2/en active Active
- 2013-09-05 MY MYPI2015700672A patent/MY176135A/en unknown
- 2013-09-05 CA CA2883767A patent/CA2883767C/en active Active
- 2013-09-05 CN CN202010052300.XA patent/CN111249247A/zh active Pending
- 2013-09-05 CU CUP2015000020A patent/CU24244B1/es unknown
- 2013-09-05 US US14/018,516 patent/US20140065212A1/en not_active Abandoned
- 2013-09-05 AP AP2015008292A patent/AP2015008292A0/xx unknown
- 2013-09-05 HK HK16102327.2A patent/HK1214170A1/zh unknown
- 2013-09-05 CN CN202310409897.2A patent/CN116392484A/zh active Pending
- 2013-09-05 CN CN201380049461.1A patent/CN104902878A/zh active Pending
- 2013-09-05 TW TW102131928A patent/TWI640329B/zh active
- 2013-09-05 PL PL13762967T patent/PL2892507T3/pl unknown
- 2013-09-05 HR HRP20170620TT patent/HRP20170620T1/hr unknown
- 2013-09-05 UA UAA201502818A patent/UA115994C2/uk unknown
- 2013-09-05 SG SG11201501683WA patent/SG11201501683WA/en unknown
- 2013-09-05 LT LTEP13762967.1T patent/LT2892507T/lt unknown
- 2013-09-05 KR KR1020157008402A patent/KR102162036B1/ko active Active
- 2013-09-05 PE PE2015000289A patent/PE20151005A1/es active IP Right Grant
- 2013-09-05 MA MA37888A patent/MA37888B1/fr unknown
- 2013-09-05 EA EA201590520A patent/EA027685B1/ru not_active IP Right Cessation
- 2013-09-05 DK DK13762967.1T patent/DK2892507T3/en active
- 2013-09-05 JP JP2015531194A patent/JP6445436B2/ja active Active
- 2013-09-05 ES ES13762967.1T patent/ES2623205T3/es active Active
- 2013-09-05 CN CN202310410047.4A patent/CN116392485A/zh active Pending
- 2013-09-05 RS RS20170400A patent/RS56019B1/sr unknown
- 2013-09-05 WO PCT/US2013/058257 patent/WO2014039677A1/en not_active Ceased
- 2013-09-05 PT PT137629671T patent/PT2892507T/pt unknown
- 2013-09-05 SI SI201330621T patent/SI2892507T1/sl unknown
- 2013-09-05 MX MX2015002815A patent/MX359922B/es active IP Right Grant
-
2015
- 2015-02-22 IL IL237350A patent/IL237350B/en active IP Right Grant
- 2015-03-02 ZA ZA2015/01394A patent/ZA201501394B/en unknown
- 2015-03-03 PH PH12015500460A patent/PH12015500460B1/en unknown
- 2015-03-04 SA SA515360113A patent/SA515360113B1/ar unknown
- 2015-03-05 CO CO15050805A patent/CO7310528A2/es unknown
- 2015-03-05 CR CR20150114A patent/CR20150114A/es unknown
- 2015-03-05 GT GT201500053A patent/GT201500053A/es unknown
- 2015-03-05 CL CL2015000544A patent/CL2015000544A1/es unknown
-
2017
- 2017-04-21 CY CY20171100450T patent/CY1118839T1/el unknown
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