SG11201501185WA - Pluripotent stem cell that induces repair and regeneration after myocardial infarction - Google Patents

Pluripotent stem cell that induces repair and regeneration after myocardial infarction

Info

Publication number
SG11201501185WA
SG11201501185WA SG11201501185WA SG11201501185WA SG11201501185WA SG 11201501185W A SG11201501185W A SG 11201501185WA SG 11201501185W A SG11201501185W A SG 11201501185WA SG 11201501185W A SG11201501185W A SG 11201501185WA SG 11201501185W A SG11201501185W A SG 11201501185WA
Authority
SG
Singapore
Prior art keywords
regeneration
stem cell
myocardial infarction
pluripotent stem
induces repair
Prior art date
Application number
SG11201501185WA
Other languages
English (en)
Inventor
Masanori Yoshida
Shinya Minatoguchi
Mari Dezawa
Original Assignee
Univ Gifu
Univ Tohoku
Clio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Gifu, Univ Tohoku, Clio Inc filed Critical Univ Gifu
Publication of SG11201501185WA publication Critical patent/SG11201501185WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
SG11201501185WA 2012-08-17 2013-08-15 Pluripotent stem cell that induces repair and regeneration after myocardial infarction SG11201501185WA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012181029 2012-08-17
PCT/JP2013/054049 WO2014027474A1 (ja) 2012-08-17 2013-02-19 心筋梗塞の修復再生を誘導する多能性幹細胞
PCT/JP2013/071981 WO2014027684A1 (ja) 2012-08-17 2013-08-15 心筋梗塞の修復再生を誘導する多能性幹細胞

Publications (1)

Publication Number Publication Date
SG11201501185WA true SG11201501185WA (en) 2015-05-28

Family

ID=50685515

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201800829XA SG10201800829XA (en) 2012-08-17 2013-08-15 Pluripotent stem cell that induces repair and regeneration after myocardial infarction
SG11201501185WA SG11201501185WA (en) 2012-08-17 2013-08-15 Pluripotent stem cell that induces repair and regeneration after myocardial infarction

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201800829XA SG10201800829XA (en) 2012-08-17 2013-08-15 Pluripotent stem cell that induces repair and regeneration after myocardial infarction

Country Status (14)

Country Link
US (3) US9844570B2 (enExample)
EP (2) EP3659612B1 (enExample)
JP (1) JP5968442B2 (enExample)
KR (1) KR101730052B1 (enExample)
CN (1) CN104582711B (enExample)
AU (1) AU2013303492B2 (enExample)
CA (1) CA2882239C (enExample)
DK (1) DK2886123T3 (enExample)
ES (1) ES2767182T3 (enExample)
IN (1) IN2015DN01616A (enExample)
PL (1) PL2886123T3 (enExample)
PT (1) PT2886123T (enExample)
SG (2) SG10201800829XA (enExample)
WO (2) WO2014027474A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014027474A1 (ja) 2012-08-17 2014-02-20 株式会社Clio 心筋梗塞の修復再生を誘導する多能性幹細胞
JP2015160820A (ja) * 2014-02-26 2015-09-07 株式会社Clio 慢性腎障害治療のための多能性幹細胞
JP6452107B2 (ja) 2014-09-05 2019-01-16 国立大学法人 東京大学 糖尿病性皮膚潰瘍治療のための多能性幹細胞
WO2016168993A1 (en) * 2015-04-22 2016-10-27 Innolife Co., Ltd. Methods of tissue repair and regeneration
JP6770673B2 (ja) * 2016-02-26 2020-10-21 国立大学法人東海国立大学機構 急性心筋梗塞の予後マーカー及びその利用
US20190201455A1 (en) * 2016-07-01 2019-07-04 Tohoku University Prophylactic or therapeutic agent for organ fibrosis
JP7029729B2 (ja) 2016-07-29 2022-03-04 国立大学法人東北大学 血管障害の予防又は治療剤
SG10202101160RA (en) * 2016-08-03 2021-03-30 Hiroshi Yabuki Alleviation and treatment of ischemia reperfusion-induced lung injury using pluripotent stem cells
US11920180B2 (en) 2016-08-03 2024-03-05 Tohoku University Method for inducing differentiation of pluripotent stem cells in vitro
WO2018025973A1 (ja) * 2016-08-03 2018-02-08 国立大学法人名古屋大学 多能性幹細胞による慢性肺疾患の改善及び治療
CN106822899B (zh) * 2017-03-10 2020-11-27 北京大学 一种通过抑制自噬促进心肌再生的药物
SG11202003507QA (en) * 2017-10-17 2020-05-28 Univ Hiroshima Pluripotent stem cells inducing osteochondral repair
JP7102666B2 (ja) * 2018-01-25 2022-07-20 国立大学法人東海国立大学機構 Muse細胞動員剤及び心筋障害への利用
JP7072777B2 (ja) * 2018-07-03 2022-05-23 株式会社生命科学インスティテュート 慢性腎障害治療のための多能性幹細胞
CN110302212A (zh) * 2019-07-17 2019-10-08 陶正博 一种用于治疗急性心肌梗死的细胞制剂及其制备方法
JP7500083B2 (ja) 2019-08-19 2024-06-17 セルアクシア株式会社 細胞含有医薬組成物
JP7627496B2 (ja) * 2019-09-05 2025-02-06 国立大学法人東北大学 心筋炎の治療剤
EP4052718A1 (en) * 2019-10-31 2022-09-07 Life Science Institute, Inc. Therapy for interstitial cystitis by pluripotent stem cells
JPWO2021201286A1 (enExample) 2020-04-02 2021-10-07
TWI825446B (zh) * 2020-08-14 2023-12-11 中國醫藥大學 醫藥組合物治療組織缺血狀況之用途
JP2021073305A (ja) * 2021-02-09 2021-05-13 株式会社生命科学インスティテュート 慢性腎障害治療のための多能性幹細胞
CN119198334A (zh) * 2024-10-31 2024-12-27 北京大学深圳研究生院 一种心肌梗死边界区组织鉴定方法

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AU4543193A (en) * 1992-06-22 1994-01-24 Henry E. Young Scar inhibitory factor and use thereof
DE69831957T3 (de) * 1997-07-14 2009-07-23 Osiris Therapeutics, Inc. Herzmuskelregenerierung unter verwendung mesenchymaler stammzellen
BR9912662A (pt) * 1998-07-31 2001-06-05 Genzyme Corp Melhoria de função cardìaca por transplante de célula de ramo mesenquimal
WO2002009650A2 (en) 2000-07-31 2002-02-07 New York Medical College Methods and compositions for the repair and/or regeneration of damaged myocardium
EP1370642A2 (en) 2001-01-20 2003-12-17 Cardion AG Pluripotent adult stem cells derived from regenerative tissue
KR20040022448A (ko) 2001-07-12 2004-03-12 제론 코포레이션 인간 다분화능 줄기 세포로부터 제조된 심근 세포 계통의세포
WO2006080434A1 (ja) 2005-01-27 2006-08-03 Japan Health Sciences Foundation 間葉系幹細胞を含む細胞シート
EP4223769A3 (en) 2005-12-13 2023-11-01 Kyoto University Nuclear reprogramming factor
CN101517069A (zh) * 2006-07-13 2009-08-26 塞拉帝思股份公司 由人类胚泡来源的干细胞衍生的多能心脏前体细胞新种群
WO2009046058A1 (en) * 2007-10-01 2009-04-09 University Of Miami A method to amplify cardiac stem cells in vitro and in vivo
EP2210608B1 (en) * 2007-11-02 2016-08-31 JCR Pharmaceuticals CO., LTD. Pharmaceutical composition containing human mesenchymal stem cell
JP5564679B2 (ja) * 2009-04-16 2014-07-30 公益財団法人ヒューマンサイエンス振興財団 心筋細胞分化誘導促進剤およびその使用方法
US9550975B2 (en) * 2009-07-15 2017-01-24 Mari Dezawa SSEA-3 pluripotent stem cell isolated from body tissue
WO2012054501A1 (en) * 2010-10-18 2012-04-26 Sunshine Biotech Inc. Human multipotent embryonic stem cell-like progenitor cells
WO2014027474A1 (ja) 2012-08-17 2014-02-20 株式会社Clio 心筋梗塞の修復再生を誘導する多能性幹細胞

Also Published As

Publication number Publication date
CA2882239A1 (en) 2014-02-20
CA2882239C (en) 2018-05-22
EP2886123A4 (en) 2016-06-22
US10376544B2 (en) 2019-08-13
WO2014027474A1 (ja) 2014-02-20
DK2886123T3 (da) 2020-01-27
AU2013303492A1 (en) 2015-03-12
JP5968442B2 (ja) 2016-08-10
PL2886123T3 (pl) 2020-05-18
EP2886123B1 (en) 2019-10-23
EP3659612B1 (en) 2023-06-07
ES2767182T3 (es) 2020-06-16
US10639335B2 (en) 2020-05-05
EP3659612A1 (en) 2020-06-03
KR20150043482A (ko) 2015-04-22
US20190307806A1 (en) 2019-10-10
EP2886123A1 (en) 2015-06-24
SG10201800829XA (en) 2018-03-28
JPWO2014027684A1 (ja) 2016-07-28
US9844570B2 (en) 2017-12-19
AU2013303492B2 (en) 2017-02-16
WO2014027684A1 (ja) 2014-02-20
US20150196600A1 (en) 2015-07-16
CN104582711B (zh) 2019-12-06
IN2015DN01616A (enExample) 2015-07-03
CN104582711A (zh) 2015-04-29
PT2886123T (pt) 2020-01-22
KR101730052B1 (ko) 2017-04-25
US20180050067A1 (en) 2018-02-22

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