SG11201407625WA - Process for making amino acid compounds - Google Patents
Process for making amino acid compoundsInfo
- Publication number
- SG11201407625WA SG11201407625WA SG11201407625WA SG11201407625WA SG11201407625WA SG 11201407625W A SG11201407625W A SG 11201407625WA SG 11201407625W A SG11201407625W A SG 11201407625WA SG 11201407625W A SG11201407625W A SG 11201407625WA SG 11201407625W A SG11201407625W A SG 11201407625WA
- Authority
- SG
- Singapore
- Prior art keywords
- lllll
- international
- llll
- amino acid
- acid compounds
- Prior art date
Links
- -1 amino acid compounds Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 101000582929 Homo sapiens Plasmolipin Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102100030265 Plasmolipin Human genes 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 239000003197 protein kinase B inhibitor Substances 0.000 abstract 1
- 125000004527 pyrimidin-4-yl group Chemical group N1=CN=C(C=C1)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/313—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of doubly bound oxygen containing functional groups, e.g. carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261648534P | 2012-05-17 | 2012-05-17 | |
| PCT/US2013/041687 WO2013173779A1 (en) | 2012-05-17 | 2013-05-17 | Process for making amino acid compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201407625WA true SG11201407625WA (en) | 2014-12-30 |
Family
ID=48483247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201407625WA SG11201407625WA (en) | 2012-05-17 | 2013-05-17 | Process for making amino acid compounds |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9278917B2 (https=) |
| EP (1) | EP2850054B1 (https=) |
| JP (1) | JP6196294B2 (https=) |
| KR (1) | KR102074535B1 (https=) |
| CN (1) | CN104520263B (https=) |
| AU (1) | AU2013262516B2 (https=) |
| BR (1) | BR112014028585B1 (https=) |
| CA (1) | CA2873658C (https=) |
| ES (1) | ES2668477T3 (https=) |
| HR (1) | HRP20180948T1 (https=) |
| IL (1) | IL235630A (https=) |
| MA (1) | MA37751B1 (https=) |
| MX (1) | MX350443B (https=) |
| MY (1) | MY171538A (https=) |
| NZ (1) | NZ702939A (https=) |
| PL (1) | PL2850054T3 (https=) |
| RU (1) | RU2643146C2 (https=) |
| SG (1) | SG11201407625WA (https=) |
| SI (1) | SI2850054T1 (https=) |
| TR (1) | TR201807444T4 (https=) |
| WO (1) | WO2013173779A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104471070B (zh) | 2012-05-17 | 2018-09-25 | 基因泰克公司 | 制备羟基化环戊并嘧啶化合物和其盐的方法 |
| HRP20200992T1 (hr) | 2012-05-17 | 2020-10-16 | Genentech, Inc. | Amorfni oblik pirimidinil-ciklopentanskog spoja koji inhibira akt, te njegovi pripravci i postupci |
| RU2014151017A (ru) | 2012-05-17 | 2016-07-10 | Аррэй Байофарма Инк. | Способ получения гидроксилированных циклопентилпиримидинов |
| AU2013262505B2 (en) | 2012-05-17 | 2017-09-21 | Array Biopharma Inc. | Process for making hydroxylated cyclopentylpyrimidine compounds |
| ES2765511T3 (es) * | 2013-11-15 | 2020-06-09 | Hoffmann La Roche | Procesos para la preparación de compuestos de pirimidinilciclopentano |
| ES2749100T3 (es) * | 2014-09-26 | 2020-03-19 | Hoffmann La Roche | Procesos para preparar compuestos de (ciclopentil[d]pirimidin-4-il)piperazina |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663327A (en) * | 1984-05-23 | 1987-05-05 | Bayer Aktiengesellschaft | 1-heteroaryl-4-aryl-pyrazolin-5-ones |
| JPH09506369A (ja) | 1993-12-12 | 1997-06-24 | アグロジーン・リミテッド | 菌類感染から植物を保護するための新規方法 |
| AU724216B2 (en) | 1997-04-07 | 2000-09-14 | Merck & Co., Inc. | A method of treating cancer |
| US6201023B1 (en) | 1997-06-10 | 2001-03-13 | Agrogene Ltd. | Methods and compositions to protect crops against plant parasitic nematodes |
| EP0982300A3 (en) | 1998-07-29 | 2000-03-08 | Societe Civile Bioprojet | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
| CA2363169A1 (en) | 1999-03-03 | 2000-09-08 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| WO2001022963A1 (en) | 1999-09-27 | 2001-04-05 | Merck & Co., Inc. | Method of preventing osteoporosis |
| JP4550811B2 (ja) | 2003-06-09 | 2010-09-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | パピローマウイルスのインヒビター |
| FR2892416B1 (fr) | 2005-10-20 | 2008-06-27 | Sanofi Aventis Sa | Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique |
| US8927546B2 (en) | 2006-02-28 | 2015-01-06 | Dart Neuroscience (Cayman) Ltd. | Therapeutic piperazines |
| UA95641C2 (xx) * | 2006-07-06 | 2011-08-25 | Эррей Биофарма Инк. | Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы |
| US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| EP2209775A1 (en) | 2007-10-09 | 2010-07-28 | UCB Pharma, S.A. | Heterobicyclic compounds as histamine h4-receptor antagonists |
| CN102459165B (zh) | 2009-04-15 | 2015-09-02 | Abbvie公司 | 抗病毒化合物 |
| MX2012004780A (es) | 2009-10-23 | 2012-08-23 | Lilly Co Eli | Inhibidores de akt. |
| EP2592933B1 (en) | 2010-07-16 | 2017-04-05 | Anderson Gaweco | Mif inhibitors and their uses |
| WO2012177925A1 (en) | 2011-06-21 | 2012-12-27 | The Board Institute, Inc. | Akt inhibitors for treating cancer expressing a magi3 - akt3 fusion gene |
| RU2014151017A (ru) | 2012-05-17 | 2016-07-10 | Аррэй Байофарма Инк. | Способ получения гидроксилированных циклопентилпиримидинов |
| CN104471070B (zh) | 2012-05-17 | 2018-09-25 | 基因泰克公司 | 制备羟基化环戊并嘧啶化合物和其盐的方法 |
| WO2014071194A2 (en) | 2012-11-01 | 2014-05-08 | Katz Robert S | Methods for treating fibromyalgia |
| WO2014127350A1 (en) | 2013-02-18 | 2014-08-21 | The Scripps Research Institute | Modulators of vasopressin receptors with therapeutic potential |
| WO2014150395A1 (en) | 2013-03-15 | 2014-09-25 | Shifa Biomedical Corporation | Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases |
-
2013
- 2013-05-17 MX MX2014013863A patent/MX350443B/es active IP Right Grant
- 2013-05-17 EP EP13724711.0A patent/EP2850054B1/en active Active
- 2013-05-17 US US14/401,095 patent/US9278917B2/en active Active
- 2013-05-17 SG SG11201407625WA patent/SG11201407625WA/en unknown
- 2013-05-17 KR KR1020147035263A patent/KR102074535B1/ko active Active
- 2013-05-17 ES ES13724711.0T patent/ES2668477T3/es active Active
- 2013-05-17 SI SI201331043T patent/SI2850054T1/en unknown
- 2013-05-17 JP JP2015512903A patent/JP6196294B2/ja active Active
- 2013-05-17 RU RU2014150991A patent/RU2643146C2/ru active
- 2013-05-17 TR TR2018/07444T patent/TR201807444T4/tr unknown
- 2013-05-17 CA CA2873658A patent/CA2873658C/en active Active
- 2013-05-17 MY MYPI2014703417A patent/MY171538A/en unknown
- 2013-05-17 MA MA37751A patent/MA37751B1/fr unknown
- 2013-05-17 NZ NZ702939A patent/NZ702939A/en not_active IP Right Cessation
- 2013-05-17 WO PCT/US2013/041687 patent/WO2013173779A1/en not_active Ceased
- 2013-05-17 CN CN201380037572.0A patent/CN104520263B/zh active Active
- 2013-05-17 HR HRP20180948TT patent/HRP20180948T1/hr unknown
- 2013-05-17 BR BR112014028585-3A patent/BR112014028585B1/pt active IP Right Grant
- 2013-05-17 AU AU2013262516A patent/AU2013262516B2/en active Active
- 2013-05-17 PL PL13724711T patent/PL2850054T3/pl unknown
-
2014
- 2014-11-11 IL IL235630A patent/IL235630A/en active IP Right Grant
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