SG11201400505YA - Endoglycosidase from streptococcus pyogenes and methods using it - Google Patents

Endoglycosidase from streptococcus pyogenes and methods using it

Info

Publication number
SG11201400505YA
SG11201400505YA SG11201400505YA SG11201400505YA SG11201400505YA SG 11201400505Y A SG11201400505Y A SG 11201400505YA SG 11201400505Y A SG11201400505Y A SG 11201400505YA SG 11201400505Y A SG11201400505Y A SG 11201400505YA SG 11201400505Y A SG11201400505Y A SG 11201400505YA
Authority
SG
Singapore
Prior art keywords
endoglycosidase
methods
streptococcus pyogenes
pyogenes
streptococcus
Prior art date
Application number
SG11201400505YA
Other languages
English (en)
Inventor
Mattias Collin
Maria Allhorn
Jonathan Sjögren
Original Assignee
Genovis Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genovis Ab filed Critical Genovis Ab
Publication of SG11201400505YA publication Critical patent/SG11201400505YA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01096Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (3.2.1.96)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56944Streptococcus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201400505YA 2011-09-13 2012-09-12 Endoglycosidase from streptococcus pyogenes and methods using it SG11201400505YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201115841A GB201115841D0 (en) 2011-09-13 2011-09-13 Protein and method
PCT/EP2012/067841 WO2013037824A1 (en) 2011-09-13 2012-09-12 Endoglycosidase from streptococcus pyogenes and methods using it

Publications (1)

Publication Number Publication Date
SG11201400505YA true SG11201400505YA (en) 2014-04-28

Family

ID=44908522

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201400505YA SG11201400505YA (en) 2011-09-13 2012-09-12 Endoglycosidase from streptococcus pyogenes and methods using it

Country Status (20)

Country Link
US (1) US9493752B2 (zh)
EP (1) EP2756077B1 (zh)
JP (1) JP6076349B2 (zh)
KR (1) KR102001427B1 (zh)
CN (1) CN103946377B (zh)
AU (1) AU2012307461B2 (zh)
BR (1) BR112014005816A2 (zh)
CA (1) CA2848230C (zh)
DK (1) DK2756077T3 (zh)
EA (1) EA028490B8 (zh)
ES (1) ES2627334T3 (zh)
GB (2) GB201115841D0 (zh)
IL (1) IL231410A0 (zh)
IN (1) IN2014CN02163A (zh)
MX (1) MX347727B (zh)
PL (1) PL2756077T3 (zh)
PT (1) PT2756077T (zh)
SG (1) SG11201400505YA (zh)
WO (1) WO2013037824A1 (zh)
ZA (1) ZA201401840B (zh)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002216863B8 (en) * 2000-12-21 2008-03-20 Id Biomedical Corporation Streptococcus pyogenes antigens and corresponding DNA fragments
LT3912642T (lt) 2012-10-23 2023-07-25 Synaffix B.V. Modifikuotas antikūnas, antikūno konjugatas ir jų gamybos būdas
ES2759503T3 (es) 2013-05-02 2020-05-11 Glykos Finland Oy Conjugados de una glicoproteína o un glicano con una carga útil tóxica
EP3058083B1 (en) 2013-10-14 2018-04-11 SynAffix B.V. Modified glycoprotein, protein-conjugate and process for the preparation thereof
WO2015057066A1 (en) 2013-10-14 2015-04-23 Synaffix B.V. Glycoengineered antibody, antibody-conjugate and methods for their preparation
WO2015057063A1 (en) 2013-10-14 2015-04-23 Synaffix B.V. Modified glycoprotein, protein-conjugate and process for the preparation thereof
WO2015057065A1 (en) 2013-10-14 2015-04-23 Synaffix B.V. Glycoengineered antibody, antibody-conjugate and methods for their preparation
GB201318490D0 (en) * 2013-10-18 2013-12-04 Genovis Ab Method
JP2017505770A (ja) 2014-01-24 2017-02-23 シンアフィックス ビー.ブイ. (ヘテロ)アリール1,3−双極子化合物と(ヘテロ)シクロアルキンとの環化付加のためのプロセス
ES2785551T3 (es) 2014-06-30 2020-10-07 Glykos Finland Oy Derivado de sacárido de una carga útil tóxica y sus conjugados con anticuerpos
GB201413240D0 (en) * 2014-07-25 2014-09-10 Hansa Medical Ab Method
JP2017528124A (ja) 2014-08-04 2017-09-28 シンアフィックス ビー.ブイ. ベータ−(1,4)−n−アセチルガラクトサミニルトランスフェラーゼ又はその突然変異体を用いる糖タンパク質の改変方法
GB201502306D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502305D0 (en) * 2015-02-12 2015-04-01 Hansa Medical Ab Protein
PL3134520T3 (pl) 2015-04-23 2018-06-29 Synaffix B.V. Sposób modyfikacji glikoproteiny z zastosowaniem glikozylotransferazy, która jest lub pochodzi od β-(1,4)-N-acetylogalaktozaminylotransferazy
US11008601B2 (en) * 2016-01-15 2021-05-18 University Of Maryland Endo-S2 mutants as glycosynthases, method of making and use for glycoengineering of glycoproteins
SG11201806639VA (en) * 2016-02-04 2018-09-27 Genovis Ab New streptococcal proteases
CA3034876C (en) * 2016-08-24 2022-10-04 CHO Pharma Inc. Endoglycosidase mutants for glycoprotein remodeling and methods of using it
FI3630968T3 (fi) 2017-05-26 2024-07-24 Genovis Ab Entsyymejä glykaanien analysointiin
US20210228738A1 (en) 2017-07-17 2021-07-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
JP2021528406A (ja) 2018-06-19 2021-10-21 グリコス バイオメディカル オーワイ コンジュゲート
EP3813883A1 (en) 2018-06-29 2021-05-05 Glykos Biomedical Oy Conjugates
WO2021123506A1 (en) 2019-12-18 2021-06-24 Glykos Biomedical Oy Stabile conjugate
CN111044731B (zh) * 2019-12-19 2021-05-07 北京科技大学 脉冲温育免疫反应分离富集多肽药物中肽类杂质的方法
AU2021205312A1 (en) 2020-01-09 2022-07-14 Mersana Therapeutics, Inc. Site specific antibody-drug conjugates with peptide-containing linkers
US20230374083A1 (en) * 2020-09-21 2023-11-23 Shanghai Bao Pharmaceuticals Co., Ltd. Pharmaceutical combination and use thereof
MX2023008000A (es) 2021-01-04 2023-07-13 Mersana Therapeutics Inc Conjugados de anticuerpo dirigido a b7-h4 y farmaco, y metodos de uso de los mismos.
EP4079848A1 (en) 2021-04-22 2022-10-26 Genovis Ab Immunoglobulin cleaving enzyme
CN115873833B (zh) * 2022-11-08 2024-08-16 上海泰昶生物技术有限公司 生产免疫球蛋白g降解酶的工程菌株和工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130228D0 (en) 2001-12-18 2002-02-06 Hansa Medica Ab Protein
GB0624874D0 (en) 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
EP2190984B1 (en) * 2007-09-14 2013-09-04 Genovis Ab Methods and kits for purification and detection of glycosylated IgG
GB0821100D0 (en) 2008-11-18 2008-12-24 Hansa Medical Ab Antibodies
CA2773882C (en) * 2009-10-02 2016-01-12 Roche Glycart Ag A-fucosylation detection in antibodies

Also Published As

Publication number Publication date
CN103946377B (zh) 2016-10-05
KR20140081813A (ko) 2014-07-01
GB201406321D0 (en) 2014-05-21
ZA201401840B (en) 2018-05-30
ES2627334T3 (es) 2017-07-27
EP2756077B1 (en) 2017-03-29
US9493752B2 (en) 2016-11-15
IN2014CN02163A (zh) 2015-05-29
EP2756077A1 (en) 2014-07-23
EA028490B1 (ru) 2017-11-30
AU2012307461A1 (en) 2014-03-27
NZ622172A (en) 2016-04-29
EA201490447A1 (ru) 2014-09-30
MX2014002906A (es) 2014-10-17
BR112014005816A2 (pt) 2020-12-29
GB2509284A (en) 2014-06-25
WO2013037824A1 (en) 2013-03-21
CA2848230A1 (en) 2013-03-21
KR102001427B1 (ko) 2019-07-18
CN103946377A (zh) 2014-07-23
IL231410A0 (en) 2014-04-30
MX347727B (es) 2017-05-10
EA028490B8 (ru) 2018-01-31
JP2014531205A (ja) 2014-11-27
AU2012307461B2 (en) 2016-08-18
PL2756077T3 (pl) 2017-09-29
DK2756077T3 (en) 2017-07-03
CA2848230C (en) 2020-03-24
US20140302519A1 (en) 2014-10-09
PT2756077T (pt) 2017-06-21
GB201115841D0 (en) 2011-10-26
JP6076349B2 (ja) 2017-02-08

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