SG104091G - Ibuprofen sustained release matrix and process - Google Patents

Ibuprofen sustained release matrix and process

Info

Publication number
SG104091G
SG104091G SG1040/91A SG104091A SG104091G SG 104091 G SG104091 G SG 104091G SG 1040/91 A SG1040/91 A SG 1040/91A SG 104091 A SG104091 A SG 104091A SG 104091 G SG104091 G SG 104091G
Authority
SG
Singapore
Prior art keywords
ibuprofen
sustained release
granulation
release matrix
erosion
Prior art date
Application number
SG1040/91A
Other languages
English (en)
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of SG104091G publication Critical patent/SG104091G/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG1040/91A 1987-04-22 1991-12-07 Ibuprofen sustained release matrix and process SG104091G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/041,164 US4806359A (en) 1987-04-22 1987-04-22 Iburprofen sustained release matrix and process

Publications (1)

Publication Number Publication Date
SG104091G true SG104091G (en) 1992-02-14

Family

ID=21915089

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1040/91A SG104091G (en) 1987-04-22 1991-12-07 Ibuprofen sustained release matrix and process

Country Status (21)

Country Link
US (1) US4806359A (pt)
EP (2) EP0290168B1 (pt)
JP (2) JP2519296B2 (pt)
KR (1) KR960007750B1 (pt)
AT (1) ATE86479T1 (pt)
AU (2) AU604110B2 (pt)
CA (1) CA1310272C (pt)
DE (2) DE3865077D1 (pt)
ES (1) ES2039277T3 (pt)
GR (1) GR1000019B (pt)
HK (1) HK22892A (pt)
IE (1) IE62786B1 (pt)
IN (1) IN165929B (pt)
MY (1) MY103076A (pt)
NO (1) NO176203C (pt)
NZ (1) NZ224278A (pt)
PH (1) PH25176A (pt)
PT (1) PT87285B (pt)
SG (1) SG104091G (pt)
WO (1) WO1988008299A1 (pt)
ZA (1) ZA882827B (pt)

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US5200193A (en) * 1987-04-22 1993-04-06 Mcneilab, Inc. Pharmaceutical sustained release matrix and process
US4999226A (en) * 1988-06-01 1991-03-12 Merrell Dow Pharmaceuticals Inc. Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination
EP0373417A1 (en) * 1988-11-30 1990-06-20 Schering Corporation Sustained release diltiazem formulation
US4911921A (en) * 1989-02-02 1990-03-27 Mallinckrodt, Inc. High ibuprofen content granulations
US5104648A (en) * 1989-02-02 1992-04-14 Mallinckrodt Specialty Chemicals Company High ibuprofen content granulations
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
KR920002148A (ko) * 1990-07-03 1992-02-28 안드레아 엘. 콜비 비스테로이드계 소염제에 의해 유발된 위장 증상을 완화시키기 위한 약제 조성물 및 이를 완화시키는 방법
FR2677886B1 (fr) * 1991-06-18 1995-03-31 Adir Comprime matriciel permettant la liberation prolongee d'indapamide apres administration par voie orale.
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140179C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Ibuprofen enthaltendes Arzneimittel
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140172C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Ibuprofen enthaltendes Arzneimittel
DE4140185C2 (de) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung
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US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
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IT1276689B1 (it) * 1995-06-09 1997-11-03 Applied Pharma Res Forma farmaceutica solida ad uso orale
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
JP3628809B2 (ja) * 1996-06-10 2005-03-16 アルケア株式会社 薬剤徐放性医療用配合物及びその製造方法
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
CA2269707C (en) * 1996-10-25 2005-08-16 Edward M. Rudnic Soluble form osmotic dose delivery system
US6361796B1 (en) * 1996-10-25 2002-03-26 Shire Laboratories, Inc. Soluble form osmotic dose delivery system
ATE313319T1 (de) * 1999-03-31 2006-01-15 Janssen Pharmaceutica Nv Vorgelatinierte stärke in einer formulierung mit gesteuerter freigabe
AR028299A1 (es) * 1999-09-17 2003-05-07 Novartis Ag Una composicion farmaceutica que comprende nateglinida, un proceso para su preparacion y el uso de dicha composicion para la preparacion de un medicamento para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con diabetes.
EP1368003A4 (en) * 2001-02-05 2004-05-12 Scherer Technologies Inc R P METHODS AND COMPOSITIONS FOR REDUCING THE TASTE OF PHARMACEUTICAL ACTIVE SUBSTANCES
US6602911B2 (en) 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
CA2479350A1 (en) * 2002-03-15 2003-09-25 Cypress Bioscience, Inc. Ne and 5-ht reuptake inhibitors for treating visceral pain syndromes
US20040132826A1 (en) * 2002-10-25 2004-07-08 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
CA2513893A1 (en) * 2003-01-28 2004-08-12 Collegium Pharmaceutical, Inc. Multiparticulate compositions of milnacipran for oral administration
JP2006528190A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
CA2533358C (en) * 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2006528189A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質産物、その使用法および製剤
CA2535398C (en) 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
US8246996B2 (en) * 2003-08-29 2012-08-21 Shionogi Inc. Antibiotic product, use and formulation thereof
CA2538064C (en) * 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005030182A1 (en) * 2003-09-26 2005-04-07 Alza Corporation Controlled release formulations exhibiting an ascending rate of release
EP1663145B1 (en) * 2003-09-26 2011-04-06 ALZA Corporation Oros-push-stick for controlled delivery of active agents
KR20120106757A (ko) * 2003-09-26 2012-09-26 알자 코포레이션 오피오이드 및 비오피오이드 진통제의 제어 방출 제제
AU2004314693B2 (en) * 2003-09-26 2011-04-07 Alza Corporation Drug coating providing high drug loading and methods for providing the same
WO2006007095A2 (en) 2004-06-30 2006-01-19 Albemarle Corporation High ibuprofen content granules and their preparation and use
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20070077297A1 (en) 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
US20060099253A1 (en) * 2004-10-20 2006-05-11 Wyeth Antibiotic product formulation
EP1909770B1 (en) * 2005-02-22 2013-03-20 Sun Pharmaceutical Industries Limited Oral controlled release composition containing levetiracetam
DE102005037630A1 (de) 2005-08-09 2007-02-15 Glatt Gmbh Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung
US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
GB0525461D0 (en) 2005-12-15 2006-01-25 Archimedes Dev Ltd Pharmaceutical compositions
CN101330904B (zh) * 2005-12-16 2012-04-18 韩美控股株式会社 含有低熔点活性成分的固体分散体以及含有它的口服给药片剂
US7749537B2 (en) 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
US8623397B2 (en) 2007-04-13 2014-01-07 The Regents Of The University Of Michigan Delivery device and method for forming the same
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CA2730005C (en) * 2008-07-21 2017-06-13 Albermarle Corporation High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
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JP6893086B2 (ja) 2013-03-13 2021-06-23 エーブリー デニソン コーポレイション 接着特性の向上
CN110037994B (zh) * 2019-05-24 2022-04-12 中国药科大学 一种布洛芬速释缓释双层片及其制备方法
CN114177155B (zh) * 2020-09-08 2023-10-03 越洋医药开发(广州)有限公司 一种布洛芬控释片及其制备方法

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US4264573A (en) * 1979-05-21 1981-04-28 Rowell Laboratories, Inc. Pharmaceutical formulation for slow release via controlled surface erosion
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US4465660A (en) * 1981-04-01 1984-08-14 Mead Johnson & Company Sustained release tablet containing at least 95 percent theophylline
FR2532177A1 (fr) * 1982-08-30 1984-03-02 Being Well Products Inc Complement nutritionnel a zones de liberation determinees et son procede de fabrication
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
CA1261260A (en) * 1984-04-16 1989-09-26 Anil Salpekar Directly compressible codeine salt compositions
US4753801A (en) * 1985-10-25 1988-06-28 Eli Lilly And Company Sustained release tablets

Also Published As

Publication number Publication date
IE62786B1 (en) 1995-02-22
PT87285B (pt) 1992-08-31
NO881732D0 (no) 1988-04-21
AU1477488A (en) 1988-10-27
ES2039277T3 (es) 1993-09-16
JPS63280021A (ja) 1988-11-17
AU1719788A (en) 1988-12-02
IN165929B (pt) 1990-02-10
NO176203C (no) 1995-02-22
HK22892A (en) 1992-04-03
DE3865077D1 (de) 1991-10-31
JP2776856B2 (ja) 1998-07-16
EP0312581A1 (en) 1989-04-26
NZ224278A (en) 1990-09-26
JPH01503070A (ja) 1989-10-19
AU604110B2 (en) 1990-12-06
CA1310272C (en) 1992-11-17
US4806359A (en) 1989-02-21
NO881732L (no) 1988-10-24
AU603675B2 (en) 1990-11-22
MY103076A (en) 1993-04-30
GR1000019B (el) 1990-01-31
JP2519296B2 (ja) 1996-07-31
KR960007750B1 (ko) 1996-06-12
PH25176A (en) 1991-03-27
NO176203B (no) 1994-11-14
PT87285A (pt) 1988-05-01
WO1988008299A1 (en) 1988-11-03
ATE86479T1 (de) 1993-03-15
IE881195L (en) 1988-10-22
EP0290168B1 (en) 1991-09-25
DE3879080T2 (de) 1993-07-15
GR880100258A (en) 1989-01-31
KR880012213A (ko) 1988-11-26
DE3879080D1 (de) 1993-04-15
EP0290168A1 (en) 1988-11-09
ZA882827B (en) 1989-12-27
EP0312581B1 (en) 1993-03-10

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