SG10201910844SA - Compositions for modulating sod-1 expression - Google Patents

Compositions for modulating sod-1 expression

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Publication number
SG10201910844SA
SG10201910844SA SG10201910844SA SG10201910844SA SG10201910844SA SG 10201910844S A SG10201910844S A SG 10201910844SA SG 10201910844S A SG10201910844S A SG 10201910844SA SG 10201910844S A SG10201910844S A SG 10201910844SA SG 10201910844S A SG10201910844S A SG 10201910844SA
Authority
SG
Singapore
Prior art keywords
expression
compositions
sod
modulating
modulating sod
Prior art date
Application number
SG10201910844SA
Other languages
English (en)
Inventor
Eric Swayze
Tracy Cole
Holly Kordasiewicz
Susan Freier
Thomas Condon
Edward Wancewicz
Trisha Lockhart
Timothy Vickers
Priyam Singh
Original Assignee
Biogen Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Ma Inc filed Critical Biogen Ma Inc
Publication of SG10201910844SA publication Critical patent/SG10201910844SA/en

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C12Y—ENZYMES
    • C12Y115/00—Oxidoreductases acting on superoxide as acceptor (1.15)
    • C12Y115/01—Oxidoreductases acting on superoxide as acceptor (1.15) with NAD or NADP as acceptor (1.15.1)
    • C12Y115/01001—Superoxide dismutase (1.15.1.1)
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/32—Chemical structure of the sugar
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    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/323—Chemical structure of the sugar modified ring structure
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/34—Spatial arrangement of the modifications
    • C12N2310/341—Gapmers, i.e. of the type ===---===
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/34—Spatial arrangement of the modifications
    • C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications

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  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
SG10201910844SA 2014-04-01 2015-04-01 Compositions for modulating sod-1 expression SG10201910844SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461973803P 2014-04-01 2014-04-01

Publications (1)

Publication Number Publication Date
SG10201910844SA true SG10201910844SA (en) 2020-01-30

Family

ID=54241435

Family Applications (3)

Application Number Title Priority Date Filing Date
SG11201608109TA SG11201608109TA (en) 2014-04-01 2015-04-01 Compositions for modulating sod-1 expression
SG10201910844SA SG10201910844SA (en) 2014-04-01 2015-04-01 Compositions for modulating sod-1 expression
SG10201906520RA SG10201906520RA (en) 2014-04-01 2015-04-01 Compositions for modulating sod-1 expression

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SG11201608109TA SG11201608109TA (en) 2014-04-01 2015-04-01 Compositions for modulating sod-1 expression

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201906520RA SG10201906520RA (en) 2014-04-01 2015-04-01 Compositions for modulating sod-1 expression

Country Status (26)

Country Link
US (3) US10385341B2 (sr)
EP (3) EP3126499B1 (sr)
JP (4) JP6622214B2 (sr)
KR (4) KR102285629B1 (sr)
CN (2) CN111440798A (sr)
AU (3) AU2015240761B2 (sr)
BR (1) BR112016021848B1 (sr)
CA (1) CA2942394A1 (sr)
CL (3) CL2016002509A1 (sr)
CY (1) CY1123288T1 (sr)
DK (2) DK3757214T3 (sr)
ES (2) ES2818236T3 (sr)
HR (2) HRP20220798T1 (sr)
HU (2) HUE050704T2 (sr)
IL (2) IL247714B (sr)
LT (2) LT3757214T (sr)
MX (2) MX2016012922A (sr)
MY (2) MY175665A (sr)
NZ (1) NZ724100A (sr)
PL (2) PL3757214T3 (sr)
PT (2) PT3757214T (sr)
RS (2) RS63487B1 (sr)
RU (1) RU2704619C2 (sr)
SG (3) SG11201608109TA (sr)
SI (2) SI3757214T1 (sr)
WO (1) WO2015153800A2 (sr)

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CL2018001897A1 (es) 2018-11-16
KR20220077933A (ko) 2022-06-09
JP2021072840A (ja) 2021-05-13
HRP20201078T1 (hr) 2020-10-30
US20200354723A1 (en) 2020-11-12
IL247714B (en) 2020-04-30
EP3757214B1 (en) 2022-06-15
BR112016021848A2 (pt) 2017-10-03
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AU2015240761A1 (en) 2016-09-22
PL3126499T3 (pl) 2020-11-30
CN106459972B (zh) 2020-05-08
RU2016142532A (ru) 2018-05-10
RS60707B1 (sr) 2020-09-30
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CN111440798A (zh) 2020-07-24
HRP20220798T1 (hr) 2022-10-14

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