SG10201902402TA - Systems and methods for two-dimensional rplc-sfc chromatography - Google Patents
Systems and methods for two-dimensional rplc-sfc chromatographyInfo
- Publication number
- SG10201902402TA SG10201902402TA SG10201902402TA SG10201902402TA SG10201902402TA SG 10201902402T A SG10201902402T A SG 10201902402TA SG 10201902402T A SG10201902402T A SG 10201902402TA SG 10201902402T A SG10201902402T A SG 10201902402TA SG 10201902402T A SG10201902402T A SG 10201902402TA
- Authority
- SG
- Singapore
- Prior art keywords
- rplc
- dimension
- chromatography
- sfc
- dimensional
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
- B01D15/1878—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series for multi-dimensional chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1885—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in parallel
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3833—Chiral chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/40—Selective adsorption, e.g. chromatography characterised by the separation mechanism using supercritical fluid as mobile phase or eluent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/462—Flow patterns using more than one column with serial coupling of separation columns with different eluents or with eluents in different states
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/201—Injection using a sampling valve multiport valves, i.e. having more than two ports
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/202—Injection using a sampling valve rotary valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/207—Injection using a sampling valve with metering cavity, e.g. sample loop
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8877—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample optical isomers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462069219P | 2014-10-27 | 2014-10-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201902402TA true SG10201902402TA (en) | 2019-04-29 |
Family
ID=54361074
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201703244TA SG11201703244TA (en) | 2014-10-27 | 2015-10-26 | Systems and methods for two-dimensional rplc-sfc chromatography |
SG10201902402TA SG10201902402TA (en) | 2014-10-27 | 2015-10-26 | Systems and methods for two-dimensional rplc-sfc chromatography |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201703244TA SG11201703244TA (en) | 2014-10-27 | 2015-10-26 | Systems and methods for two-dimensional rplc-sfc chromatography |
Country Status (22)
Country | Link |
---|---|
US (3) | US10101306B2 (pt) |
EP (3) | EP3798630A1 (pt) |
JP (3) | JP6646057B2 (pt) |
KR (3) | KR20210049180A (pt) |
CN (2) | CN110514770A (pt) |
AU (3) | AU2015340750B2 (pt) |
BR (1) | BR112017005703A2 (pt) |
CA (1) | CA2960469C (pt) |
DK (1) | DK3213065T3 (pt) |
ES (1) | ES2831012T3 (pt) |
HR (1) | HRP20201799T1 (pt) |
HU (1) | HUE051209T2 (pt) |
IL (1) | IL251233A0 (pt) |
LT (1) | LT3213065T (pt) |
MX (1) | MX2017004784A (pt) |
PL (1) | PL3213065T3 (pt) |
PT (1) | PT3213065T (pt) |
RS (1) | RS61088B1 (pt) |
RU (1) | RU2678921C2 (pt) |
SG (2) | SG11201703244TA (pt) |
SI (1) | SI3213065T1 (pt) |
WO (1) | WO2016066569A1 (pt) |
Families Citing this family (26)
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CN110514770A (zh) | 2014-10-27 | 2019-11-29 | 豪夫迈·罗氏有限公司 | 用于两向rplc-sfc色谱的系统和方法 |
DE102017101012A1 (de) | 2016-01-22 | 2017-07-27 | Waters Technologies Corporation | At-column dilution verwendendes mehrdimensionales chromatographiesystem |
DE102017101427A1 (de) * | 2016-01-25 | 2017-07-27 | Waters Technologies Corporation | Mehrdimensionales Chromatographiesystem zur Analyse multipler Probenkomponenten |
US20200041467A1 (en) * | 2016-09-28 | 2020-02-06 | Evosep Aps | Chromatographic analysis with low pressure dual gradient refocusing |
DE102016121516B4 (de) | 2016-11-10 | 2019-03-28 | Dionex Softron Gmbh | Verfahren und Vorrichtung zur Probenbeschickung |
US11415563B2 (en) * | 2017-04-13 | 2022-08-16 | Shimadzu Corporation | Method for analyzing sample by liquid chromatograph mass spectrometry |
US10921295B2 (en) * | 2017-09-08 | 2021-02-16 | Elemental Scientific, Inc. | Automated system for detection of silicon species in phosphoric acid |
WO2019130460A1 (ja) * | 2017-12-27 | 2019-07-04 | 株式会社島津製作所 | 二次元液体クロマトグラフシステム |
CN110243951A (zh) * | 2018-03-09 | 2019-09-17 | 株式会社岛津制作所 | 超临界流体萃取仪与液质联用仪的连接装置 |
CN112074723A (zh) * | 2018-04-30 | 2020-12-11 | 安捷伦科技有限公司 | 具有压力调节的多维样品分离 |
EP3572137A1 (en) * | 2018-05-24 | 2019-11-27 | Biotage AB | Conditioning of packed chromatography columns |
US11173418B2 (en) * | 2018-07-11 | 2021-11-16 | Waters Technologies Corporation | Materials and methods for trap-elute mixed mode chromatography |
US11307181B1 (en) | 2018-07-14 | 2022-04-19 | Sielc Technologies Corporation | HPLC system with mixed-mode columns for measuring charged analytes in complex mixtures |
US11307183B2 (en) * | 2018-07-18 | 2022-04-19 | Waters Technologies Corporation | Methods for determination of polar pesticides by chromatography |
EP3847454A1 (en) * | 2018-09-05 | 2021-07-14 | Waters Technologies Corporation | Interface module for two-dimensional liquid chromatography |
JP7319720B2 (ja) | 2018-10-25 | 2023-08-02 | エンテック インスツルメンツ インコーポレイテッド | 化学試料の圧力制御分離のシステム及び方法 |
CN113474647B (zh) * | 2019-03-13 | 2024-01-23 | 株式会社岛津制作所 | 色谱仪用自动进样器 |
CN111896633B (zh) * | 2019-05-05 | 2022-12-27 | 株式会社岛津制作所 | 分析系统 |
CN110146631B (zh) * | 2019-06-25 | 2021-11-12 | 山西康宝生物制品股份有限公司 | 一种药用材料中聚乙二醇单甲醚残留量的检测方法 |
CN110320310B (zh) * | 2019-08-02 | 2021-06-08 | 中国科学院新疆理化技术研究所 | 一种在线监测异构化动力学的方法 |
DE102019123373A1 (de) * | 2019-08-30 | 2021-03-04 | Dionex Softron Gmbh | Verfahren und System für zweidimensionale Chromatografie |
CN110646536A (zh) * | 2019-09-26 | 2020-01-03 | 上海烟草集团有限责任公司 | 一种卷烟主流烟气中烟草特有亚硝胺的在线二维色谱串联质谱的测定方法 |
US11709154B2 (en) * | 2019-10-17 | 2023-07-25 | Aisti Science Co., Ltd. | Liquid chromatograph including passage switch valve |
US11951475B2 (en) | 2020-05-22 | 2024-04-09 | Waters Technologies Corporation | Multiple sample channel device for liquid chromatography |
US20210382021A1 (en) * | 2020-06-09 | 2021-12-09 | Waters Technologies Corporation | Systems and methods for two-dimensional liquid chromatography using size exclusion chromatography as a first dimension |
CN116829937A (zh) * | 2021-01-26 | 2023-09-29 | 沃特世科技公司 | 具有旁路状态的旋转阀 |
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JPH08313508A (ja) * | 1995-05-19 | 1996-11-29 | Dkk Corp | パージ方法及びパージ・トラップ装置 |
DE19807063A1 (de) * | 1998-02-20 | 1999-08-26 | Merck Patent Gmbh | Gepackte Kapillaren, insbesondere für die Enantiomerentrennung |
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CN101619090A (zh) * | 2008-07-02 | 2010-01-06 | 中国科学院大连化学物理研究所 | 用于生物大分子分离纯化的柱切换循环体积排阻色谱系统 |
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US8650936B2 (en) * | 2011-07-11 | 2014-02-18 | Korea University Research And Business Foundation | Liquid chromatography device |
JP2013134095A (ja) | 2011-12-26 | 2013-07-08 | Olympus Corp | 共焦点顕微鏡又は多光子顕微鏡の光学系を用いた光分析装置 |
WO2013167193A1 (en) | 2012-05-10 | 2013-11-14 | Agilent Technologies, Inc. | Two-dimensional fluid separation with controlled pressure |
EP2677313A1 (en) * | 2012-06-22 | 2013-12-25 | Agilent Technologies, Inc. | Compressible fluid pumping system for dynamically compensating compressible fluids over large pressure ranges |
CN103134889B (zh) * | 2013-01-25 | 2015-03-04 | 中山大学 | 在线富集-分步聚焦进样-超高效液相色谱联用系统及应用 |
CN110514770A (zh) | 2014-10-27 | 2019-11-29 | 豪夫迈·罗氏有限公司 | 用于两向rplc-sfc色谱的系统和方法 |
US10788462B2 (en) | 2018-06-29 | 2020-09-29 | The Boeing Company | Dual function non-destructive inspection apparatus and method |
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2015
- 2015-10-26 CN CN201910647926.2A patent/CN110514770A/zh active Pending
- 2015-10-26 CA CA2960469A patent/CA2960469C/en active Active
- 2015-10-26 PT PT157871807T patent/PT3213065T/pt unknown
- 2015-10-26 SI SI201531415T patent/SI3213065T1/sl unknown
- 2015-10-26 HU HUE15787180A patent/HUE051209T2/hu unknown
- 2015-10-26 MX MX2017004784A patent/MX2017004784A/es unknown
- 2015-10-26 RU RU2017116685A patent/RU2678921C2/ru active
- 2015-10-26 DK DK15787180.7T patent/DK3213065T3/da active
- 2015-10-26 SG SG11201703244TA patent/SG11201703244TA/en unknown
- 2015-10-26 SG SG10201902402TA patent/SG10201902402TA/en unknown
- 2015-10-26 JP JP2017541164A patent/JP6646057B2/ja active Active
- 2015-10-26 EP EP20185425.4A patent/EP3798630A1/en not_active Withdrawn
- 2015-10-26 KR KR1020217011811A patent/KR20210049180A/ko not_active Application Discontinuation
- 2015-10-26 PL PL15787180T patent/PL3213065T3/pl unknown
- 2015-10-26 US US14/923,273 patent/US10101306B2/en active Active
- 2015-10-26 EP EP15787180.7A patent/EP3213065B1/en active Active
- 2015-10-26 WO PCT/EP2015/074695 patent/WO2016066569A1/en active Application Filing
- 2015-10-26 AU AU2015340750A patent/AU2015340750B2/en not_active Ceased
- 2015-10-26 ES ES15787180T patent/ES2831012T3/es active Active
- 2015-10-26 CN CN201580057626.9A patent/CN107073358B/zh active Active
- 2015-10-26 KR KR1020197010617A patent/KR102244882B1/ko active IP Right Grant
- 2015-10-26 EP EP20166295.4A patent/EP3754332A1/en active Pending
- 2015-10-26 LT LTEP15787180.7T patent/LT3213065T/lt unknown
- 2015-10-26 BR BR112017005703-4A patent/BR112017005703A2/pt active Search and Examination
- 2015-10-26 RS RS20201370A patent/RS61088B1/sr unknown
- 2015-10-26 KR KR1020177011249A patent/KR101975686B1/ko active IP Right Grant
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2017
- 2017-03-16 IL IL251233A patent/IL251233A0/en unknown
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2018
- 2018-09-07 US US16/125,427 patent/US10788467B2/en active Active
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2019
- 2019-04-08 AU AU2019202439A patent/AU2019202439B2/en not_active Ceased
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2020
- 2020-01-09 JP JP2020001805A patent/JP7177103B2/ja active Active
- 2020-08-27 US US17/005,111 patent/US11340199B2/en active Active
- 2020-11-10 HR HRP20201799TT patent/HRP20201799T1/hr unknown
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2021
- 2021-05-20 AU AU2021203243A patent/AU2021203243A1/en not_active Abandoned
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2022
- 2022-11-10 JP JP2022180033A patent/JP2023001316A/ja active Pending
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