RS61088B1 - Sistemi i postupci za dvodimenzionalnu rplc-sfc hromatografiju - Google Patents
Sistemi i postupci za dvodimenzionalnu rplc-sfc hromatografijuInfo
- Publication number
- RS61088B1 RS61088B1 RS20201370A RSP20201370A RS61088B1 RS 61088 B1 RS61088 B1 RS 61088B1 RS 20201370 A RS20201370 A RS 20201370A RS P20201370 A RSP20201370 A RS P20201370A RS 61088 B1 RS61088 B1 RS 61088B1
- Authority
- RS
- Serbia
- Prior art keywords
- methods
- sfc chromatography
- rplc
- dimensional
- dimensional rplc
- Prior art date
Links
- 238000004587 chromatography analysis Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
- B01D15/1878—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series for multi-dimensional chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1885—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in parallel
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3833—Chiral chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/40—Selective adsorption, e.g. chromatography characterised by the separation mechanism using supercritical fluid as mobile phase or eluent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/462—Flow patterns using more than one column with serial coupling of separation columns with different eluents or with eluents in different states
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/201—Injection using a sampling valve multiport valves, i.e. having more than two ports
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/202—Injection using a sampling valve rotary valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/207—Injection using a sampling valve with metering cavity, e.g. sample loop
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8877—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pathology (AREA)
- Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462069219P | 2014-10-27 | 2014-10-27 | |
PCT/EP2015/074695 WO2016066569A1 (en) | 2014-10-27 | 2015-10-26 | Systems and methods for two-dimensional rplc-sfc chromatography |
EP15787180.7A EP3213065B1 (en) | 2014-10-27 | 2015-10-26 | System and methods for two-dimensional rplc-sfc chromatography |
Publications (1)
Publication Number | Publication Date |
---|---|
RS61088B1 true RS61088B1 (sr) | 2020-12-31 |
Family
ID=54361074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20201370A RS61088B1 (sr) | 2014-10-27 | 2015-10-26 | Sistemi i postupci za dvodimenzionalnu rplc-sfc hromatografiju |
Country Status (22)
Country | Link |
---|---|
US (3) | US10101306B2 (sr) |
EP (3) | EP3213065B1 (sr) |
JP (3) | JP6646057B2 (sr) |
KR (3) | KR20210049180A (sr) |
CN (2) | CN107073358B (sr) |
AU (3) | AU2015340750B2 (sr) |
BR (1) | BR112017005703A2 (sr) |
CA (1) | CA2960469C (sr) |
DK (1) | DK3213065T3 (sr) |
ES (1) | ES2831012T3 (sr) |
HR (1) | HRP20201799T1 (sr) |
HU (1) | HUE051209T2 (sr) |
IL (1) | IL251233A0 (sr) |
LT (1) | LT3213065T (sr) |
MX (1) | MX2017004784A (sr) |
PL (1) | PL3213065T3 (sr) |
PT (1) | PT3213065T (sr) |
RS (1) | RS61088B1 (sr) |
RU (1) | RU2678921C2 (sr) |
SG (2) | SG10201902402TA (sr) |
SI (1) | SI3213065T1 (sr) |
WO (1) | WO2016066569A1 (sr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
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EP3213065B1 (en) | 2014-10-27 | 2020-08-26 | F. Hoffmann-La Roche AG | System and methods for two-dimensional rplc-sfc chromatography |
DE102017101012A1 (de) | 2016-01-22 | 2017-07-27 | Waters Technologies Corporation | At-column dilution verwendendes mehrdimensionales chromatographiesystem |
DE102017101427A1 (de) * | 2016-01-25 | 2017-07-27 | Waters Technologies Corporation | Mehrdimensionales Chromatographiesystem zur Analyse multipler Probenkomponenten |
CN110178027A (zh) * | 2016-09-28 | 2019-08-27 | 埃沃赛普私人有限责任公司 | 使用低压双重梯度再集中的色谱分析 |
DE102016121516B4 (de) | 2016-11-10 | 2019-03-28 | Dionex Softron Gmbh | Verfahren und Vorrichtung zur Probenbeschickung |
JP6933343B2 (ja) * | 2017-04-13 | 2021-09-08 | 株式会社島津製作所 | 液体クロマトグラフ質量分析による試料分析方法 |
US10921295B2 (en) * | 2017-09-08 | 2021-02-16 | Elemental Scientific, Inc. | Automated system for detection of silicon species in phosphoric acid |
EP3734269B1 (en) * | 2017-12-27 | 2024-03-27 | Shimadzu Corporation | Two-dimensional liquid chromatography system |
CN110243951A (zh) * | 2018-03-09 | 2019-09-17 | 株式会社岛津制作所 | 超临界流体萃取仪与液质联用仪的连接装置 |
US11933769B2 (en) | 2018-04-30 | 2024-03-19 | Agilent Technologies, Inc. | Multidimensional sample separation with pressure adjustment |
EP3572137B1 (en) * | 2018-05-24 | 2024-06-19 | Biotage AB | Conditioning of packed chromatography columns |
EP3821238B1 (en) * | 2018-07-11 | 2022-08-31 | Waters Technologies Corporation | Chromatographic system and method for trap-elute mixed mode chromatography |
US11307181B1 (en) | 2018-07-14 | 2022-04-19 | Sielc Technologies Corporation | HPLC system with mixed-mode columns for measuring charged analytes in complex mixtures |
US11307183B2 (en) * | 2018-07-18 | 2022-04-19 | Waters Technologies Corporation | Methods for determination of polar pesticides by chromatography |
US11360056B2 (en) * | 2018-09-05 | 2022-06-14 | Waters Technologies Corporation | Interface module for two-dimensional liquid chromatography |
EP3849682B1 (en) | 2018-10-25 | 2024-06-05 | Entech Instruments Inc. | System and method of pressure-controlled splitting of a chemical sample |
JP7156496B2 (ja) * | 2019-03-13 | 2022-10-19 | 株式会社島津製作所 | クロマトグラフ用オートサンプラ |
CN111896633B (zh) * | 2019-05-05 | 2022-12-27 | 株式会社岛津制作所 | 分析系统 |
CN110146631B (zh) * | 2019-06-25 | 2021-11-12 | 山西康宝生物制品股份有限公司 | 一种药用材料中聚乙二醇单甲醚残留量的检测方法 |
CN110320310B (zh) * | 2019-08-02 | 2021-06-08 | 中国科学院新疆理化技术研究所 | 一种在线监测异构化动力学的方法 |
DE102019123373A1 (de) * | 2019-08-30 | 2021-03-04 | Dionex Softron Gmbh | Verfahren und System für zweidimensionale Chromatografie |
CN110646536A (zh) * | 2019-09-26 | 2020-01-03 | 上海烟草集团有限责任公司 | 一种卷烟主流烟气中烟草特有亚硝胺的在线二维色谱串联质谱的测定方法 |
US11709154B2 (en) * | 2019-10-17 | 2023-07-25 | Aisti Science Co., Ltd. | Liquid chromatograph including passage switch valve |
CN115698702A (zh) | 2020-05-22 | 2023-02-03 | 沃特世科技公司 | 用于液相色谱的多样品通道装置 |
US20210382021A1 (en) * | 2020-06-09 | 2021-12-09 | Waters Technologies Corporation | Systems and methods for two-dimensional liquid chromatography using size exclusion chromatography as a first dimension |
US11506641B2 (en) | 2021-01-26 | 2022-11-22 | Waters Technologies Corporation | Rotary valve having bypass state |
CN118425391A (zh) * | 2023-01-31 | 2024-08-02 | 岛津企业管理(中国)有限公司 | 检测系统以及手性化合物检测方法 |
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US4845985A (en) | 1988-02-17 | 1989-07-11 | Hewlett-Packard Company | Supercritical fluid chromatography |
US5139681A (en) | 1990-10-09 | 1992-08-18 | The Dow Chemical Company | On-line multidimensional chromatographic system with large volume injection handling for supercritical fluid chromatography |
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JPH08313508A (ja) * | 1995-05-19 | 1996-11-29 | Dkk Corp | パージ方法及びパージ・トラップ装置 |
DE19807063A1 (de) * | 1998-02-20 | 1999-08-26 | Merck Patent Gmbh | Gepackte Kapillaren, insbesondere für die Enantiomerentrennung |
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US8215922B2 (en) * | 2008-06-24 | 2012-07-10 | Aurora Sfc Systems, Inc. | Compressible fluid pumping system for dynamically compensating compressible fluids over large pressure ranges |
CN101619090A (zh) * | 2008-07-02 | 2010-01-06 | 中国科学院大连化学物理研究所 | 用于生物大分子分离纯化的柱切换循环体积排阻色谱系统 |
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WO2010118414A1 (en) * | 2009-04-10 | 2010-10-14 | Waters Technologies Corporation | Apparatus and method for coupled lc-nmr analysis |
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CN103930778A (zh) | 2011-03-23 | 2014-07-16 | 明尼苏达大学评议会 | 用于多维液体分析的阀和分流系统 |
US8716025B2 (en) | 2011-07-08 | 2014-05-06 | Agilent Technologies, Inc. | Drifting two-dimensional separation with adaption of second dimension gradient to actual first dimension condition |
US8650936B2 (en) * | 2011-07-11 | 2014-02-18 | Korea University Research And Business Foundation | Liquid chromatography device |
JP2013134095A (ja) | 2011-12-26 | 2013-07-08 | Olympus Corp | 共焦点顕微鏡又は多光子顕微鏡の光学系を用いた光分析装置 |
US9694301B2 (en) | 2012-05-10 | 2017-07-04 | Agilent Technologies, Inc. | Two-dimensional fluid separation with controlled pressure |
EP2677313A1 (en) * | 2012-06-22 | 2013-12-25 | Agilent Technologies, Inc. | Compressible fluid pumping system for dynamically compensating compressible fluids over large pressure ranges |
CN103134889B (zh) * | 2013-01-25 | 2015-03-04 | 中山大学 | 在线富集-分步聚焦进样-超高效液相色谱联用系统及应用 |
EP3213065B1 (en) | 2014-10-27 | 2020-08-26 | F. Hoffmann-La Roche AG | System and methods for two-dimensional rplc-sfc chromatography |
US10788462B2 (en) | 2018-06-29 | 2020-09-29 | The Boeing Company | Dual function non-destructive inspection apparatus and method |
-
2015
- 2015-10-26 EP EP15787180.7A patent/EP3213065B1/en active Active
- 2015-10-26 AU AU2015340750A patent/AU2015340750B2/en not_active Ceased
- 2015-10-26 EP EP20185425.4A patent/EP3798630A1/en not_active Withdrawn
- 2015-10-26 MX MX2017004784A patent/MX2017004784A/es unknown
- 2015-10-26 HU HUE15787180A patent/HUE051209T2/hu unknown
- 2015-10-26 KR KR1020217011811A patent/KR20210049180A/ko not_active Application Discontinuation
- 2015-10-26 SI SI201531415T patent/SI3213065T1/sl unknown
- 2015-10-26 US US14/923,273 patent/US10101306B2/en active Active
- 2015-10-26 LT LTEP15787180.7T patent/LT3213065T/lt unknown
- 2015-10-26 DK DK15787180.7T patent/DK3213065T3/da active
- 2015-10-26 SG SG10201902402TA patent/SG10201902402TA/en unknown
- 2015-10-26 WO PCT/EP2015/074695 patent/WO2016066569A1/en active Application Filing
- 2015-10-26 KR KR1020177011249A patent/KR101975686B1/ko active IP Right Grant
- 2015-10-26 BR BR112017005703-4A patent/BR112017005703A2/pt active Search and Examination
- 2015-10-26 EP EP20166295.4A patent/EP3754332A1/en active Pending
- 2015-10-26 CN CN201580057626.9A patent/CN107073358B/zh active Active
- 2015-10-26 KR KR1020197010617A patent/KR102244882B1/ko active IP Right Grant
- 2015-10-26 CA CA2960469A patent/CA2960469C/en not_active Expired - Fee Related
- 2015-10-26 SG SG11201703244TA patent/SG11201703244TA/en unknown
- 2015-10-26 RU RU2017116685A patent/RU2678921C2/ru active
- 2015-10-26 PL PL15787180T patent/PL3213065T3/pl unknown
- 2015-10-26 CN CN201910647926.2A patent/CN110514770A/zh active Pending
- 2015-10-26 PT PT157871807T patent/PT3213065T/pt unknown
- 2015-10-26 JP JP2017541164A patent/JP6646057B2/ja active Active
- 2015-10-26 RS RS20201370A patent/RS61088B1/sr unknown
- 2015-10-26 ES ES15787180T patent/ES2831012T3/es active Active
-
2017
- 2017-03-16 IL IL251233A patent/IL251233A0/en unknown
-
2018
- 2018-09-07 US US16/125,427 patent/US10788467B2/en active Active
-
2019
- 2019-04-08 AU AU2019202439A patent/AU2019202439B2/en not_active Ceased
-
2020
- 2020-01-09 JP JP2020001805A patent/JP7177103B2/ja active Active
- 2020-08-27 US US17/005,111 patent/US11340199B2/en active Active
- 2020-11-10 HR HRP20201799TT patent/HRP20201799T1/hr unknown
-
2021
- 2021-05-20 AU AU2021203243A patent/AU2021203243A1/en not_active Abandoned
-
2022
- 2022-11-10 JP JP2022180033A patent/JP2023001316A/ja not_active Ceased
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