SG10201700973YA - Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering - Google Patents
Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineeringInfo
- Publication number
- SG10201700973YA SG10201700973YA SG10201700973YA SG10201700973YA SG10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA
- Authority
- SG
- Singapore
- Prior art keywords
- manufacturing
- scaffold
- compositions
- methods
- living cells
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/08—Methods for forming porous structures using a negative form which is filled and then removed by pyrolysis or dissolution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261680854P | 2012-08-08 | 2012-08-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201700973YA true SG10201700973YA (en) | 2017-04-27 |
Family
ID=50068421
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201500188YA SG11201500188YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
SG10201700973YA SG10201700973YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201500188YA SG11201500188YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
Country Status (5)
Country | Link |
---|---|
US (1) | US9974886B2 (de) |
EP (1) | EP2882465B1 (de) |
CN (1) | CN104582747B (de) |
SG (2) | SG11201500188YA (de) |
WO (1) | WO2014025312A1 (de) |
Families Citing this family (75)
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US8822663B2 (en) | 2010-08-06 | 2014-09-02 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
CA3162352A1 (en) | 2010-10-01 | 2012-04-05 | Modernatx, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
AU2012236099A1 (en) | 2011-03-31 | 2013-10-03 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
US9428535B2 (en) | 2011-10-03 | 2016-08-30 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
EP2791160B1 (de) | 2011-12-16 | 2022-03-02 | ModernaTX, Inc. | Modifizierte mrna zusammensetzungen |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
AU2013243946A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of membrane proteins |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
LT2922554T (lt) | 2012-11-26 | 2022-06-27 | Modernatx, Inc. | Terminaliai modifikuota rnr |
EP2971010B1 (de) | 2013-03-14 | 2020-06-10 | ModernaTX, Inc. | Formulierung und abgabe von modifizierten nukleosid-, nukleotid- und nukleinsäurezusammensetzungen |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
CA2926218A1 (en) | 2013-10-03 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
JP6338468B2 (ja) * | 2014-06-19 | 2018-06-06 | テルモ株式会社 | 細胞を分散したゲルの製造方法およびその製造方法により製造された細胞分散ゲル |
WO2016011387A1 (en) | 2014-07-17 | 2016-01-21 | The Regents Of The University Of California | Controllable self-annealing microgel particles for biomedical applications |
CN104491846B (zh) * | 2014-12-04 | 2018-05-11 | 常州药物研究所有限公司 | 一种复合交联医用几丁糖制剂及其制备方法 |
ES2745696T3 (es) | 2014-12-05 | 2020-03-03 | Univ Florida | Impresión 3D utilizando materiales de cambio de fase como soporte |
CN105734017B (zh) * | 2014-12-09 | 2019-11-12 | 中国科学院大连化学物理研究所 | 一种促进间充质干细胞向神经前体细胞定向分化、增殖的方法 |
CN104399118B (zh) * | 2014-12-10 | 2017-11-17 | 武汉理工大学 | 一种神经生长因子可注射原位水凝胶、制备及其应用 |
WO2016130953A1 (en) | 2015-02-13 | 2016-08-18 | University Of Florida Research Foundation, Inc. | High speed 3d printing system for wound and tissue replacement |
JP6998215B2 (ja) * | 2015-05-08 | 2022-02-10 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 3次元細胞培養のための成長培地 |
CN104922734B (zh) * | 2015-05-21 | 2017-11-24 | 东南大学 | 促进心肌修复的可注射壳聚糖复合水凝胶及其制备方法 |
CN105078607A (zh) * | 2015-06-26 | 2015-11-25 | 王向阳 | 重建兔椎体终板内血管3d结构的实验方法 |
CN106367467B (zh) * | 2015-07-24 | 2019-11-26 | 中国科学院大连化学物理研究所 | 一种移植用水凝胶微球的体外筛选方法 |
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US11931480B2 (en) | 2016-02-16 | 2024-03-19 | The Regents Of The University Of California | Microporous annealed particle gels and methods of use |
CN109642213B (zh) | 2016-03-01 | 2023-02-24 | 牛津大学创新有限公司 | 载有装载的支架的相转移 |
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TWI659939B (zh) * | 2017-06-23 | 2019-05-21 | 高雄醫學大學 | 具有主動緩釋放效應之陶瓷材料,其製造方法及包含此陶瓷材料之系統 |
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CN108410803B (zh) * | 2018-03-28 | 2019-02-05 | 湖南源品细胞生物科技有限公司 | 一种诱导脂肪干细胞成软骨分化的培养方法和培养液 |
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CN108841776B (zh) * | 2018-06-13 | 2022-05-10 | 河海大学常州校区 | 一种成分可调控的3d凝胶的制备方法及应用 |
CN108815574B (zh) * | 2018-07-17 | 2021-04-06 | 深圳市晶莱新材料科技有限公司 | 骨修复水凝胶支架及其制备方法 |
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CA3190689A1 (en) | 2020-08-31 | 2022-03-03 | The Board Of Trustees Of University Of Illinois | Alginate-coated mesenchymal stromal and progenitor cells and methods for using the same |
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CN115553469B (zh) * | 2022-09-27 | 2023-10-03 | 六安益普罗科技有限公司 | 一种胃黏膜粘附的益生菌缓释微球、制备方法及用于制备抗幽门螺旋杆菌或缓解胃黏膜炎的药物 |
CN116870243B (zh) * | 2023-08-10 | 2024-01-19 | 广州创赛生物医用材料有限公司 | 一种具有止血抗炎作用的水凝胶及其制备方法和应用 |
CN117547554B (zh) * | 2024-01-12 | 2024-05-14 | 山东康根源生物集团有限公司 | 一种间充质干细胞修复制剂及其制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4798786A (en) * | 1982-05-06 | 1989-01-17 | Stolle Research And Development Corporation | Living cells encapsulated in crosslinked protein |
DE10042484A1 (de) * | 2000-08-29 | 2002-03-28 | Merck Patent Gmbh | Verfahren zur Herstellung von humanen Knorpelimplantaten mittels in vitro gezüchteter Chondrozyten |
EP2229147A2 (de) * | 2007-12-03 | 2010-09-22 | The Johns Hopkins University | Synthese- und anwendungsverfahren für chemosphären |
EP2429600B1 (de) * | 2009-05-15 | 2017-09-06 | Nanyang Technological University | Zusammensetzung zur herstellung eines gerüsts zur gewebezüchtung und herstellungsverfahren dafür |
-
2013
- 2013-07-26 WO PCT/SG2013/000312 patent/WO2014025312A1/en active Application Filing
- 2013-07-26 US US14/420,278 patent/US9974886B2/en active Active
- 2013-07-26 SG SG11201500188YA patent/SG11201500188YA/en unknown
- 2013-07-26 EP EP13828142.3A patent/EP2882465B1/de not_active Not-in-force
- 2013-07-26 SG SG10201700973YA patent/SG10201700973YA/en unknown
- 2013-07-26 CN CN201380042205.XA patent/CN104582747B/zh active Active
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Publication number | Publication date |
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WO2014025312A1 (en) | 2014-02-13 |
CN104582747B (zh) | 2016-12-21 |
EP2882465B1 (de) | 2019-05-08 |
SG11201500188YA (en) | 2015-02-27 |
CN104582747A (zh) | 2015-04-29 |
US9974886B2 (en) | 2018-05-22 |
US20150217024A1 (en) | 2015-08-06 |
EP2882465A4 (de) | 2016-04-06 |
EP2882465A1 (de) | 2015-06-17 |
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