SG10201700973YA - Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering - Google Patents
Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineeringInfo
- Publication number
- SG10201700973YA SG10201700973YA SG10201700973YA SG10201700973YA SG10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA
- Authority
- SG
- Singapore
- Prior art keywords
- manufacturing
- scaffold
- compositions
- methods
- living cells
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/08—Methods for forming porous structures using a negative form which is filled and then removed by pyrolysis or dissolution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261680854P | 2012-08-08 | 2012-08-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201700973YA true SG10201700973YA (en) | 2017-04-27 |
Family
ID=50068421
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201500188YA SG11201500188YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
SG10201700973YA SG10201700973YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201500188YA SG11201500188YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
Country Status (5)
Country | Link |
---|---|
US (1) | US9974886B2 (en) |
EP (1) | EP2882465B1 (en) |
CN (1) | CN104582747B (en) |
SG (2) | SG11201500188YA (en) |
WO (1) | WO2014025312A1 (en) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8822663B2 (en) | 2010-08-06 | 2014-09-02 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
CA3162352A1 (en) | 2010-10-01 | 2012-04-05 | Modernatx, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
AU2012236099A1 (en) | 2011-03-31 | 2013-10-03 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
US9428535B2 (en) | 2011-10-03 | 2016-08-30 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
EP2791160B1 (en) | 2011-12-16 | 2022-03-02 | ModernaTX, Inc. | Modified mrna compositions |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
AU2013243946A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of membrane proteins |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
LT2922554T (en) | 2012-11-26 | 2022-06-27 | Modernatx, Inc. | Terminally modified rna |
EP2971010B1 (en) | 2013-03-14 | 2020-06-10 | ModernaTX, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
CA2926218A1 (en) | 2013-10-03 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
JP6338468B2 (en) * | 2014-06-19 | 2018-06-06 | テルモ株式会社 | Method for producing gel in which cells are dispersed and cell-dispersed gel produced by the method |
WO2016011387A1 (en) | 2014-07-17 | 2016-01-21 | The Regents Of The University Of California | Controllable self-annealing microgel particles for biomedical applications |
CN104491846B (en) * | 2014-12-04 | 2018-05-11 | 常州药物研究所有限公司 | A kind of composite crosslinking medical chitose preparation and preparation method thereof |
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CN104399118B (en) * | 2014-12-10 | 2017-11-17 | 武汉理工大学 | A kind of nerve growth factor Injectable in-situ hydrogel, preparation and its application |
WO2016130953A1 (en) | 2015-02-13 | 2016-08-18 | University Of Florida Research Foundation, Inc. | High speed 3d printing system for wound and tissue replacement |
JP6998215B2 (en) * | 2015-05-08 | 2022-02-10 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | Growth medium for 3D cell culture |
CN104922734B (en) * | 2015-05-21 | 2017-11-24 | 东南大学 | Promote injectable chitosan composite aquogel of myocardial repair and preparation method thereof |
CN105078607A (en) * | 2015-06-26 | 2015-11-25 | 王向阳 | Experimental method for reconstructing vascular 3D structure inside rabbit vertebral end-plate |
CN106367467B (en) * | 2015-07-24 | 2019-11-26 | 中国科学院大连化学物理研究所 | A kind of transplanting in-vitro screening method of hydrogel microsphere |
WO2017040981A1 (en) | 2015-09-03 | 2017-03-09 | University Of Florida Research Foundation, Inc. | Valve incorporating temporary phase change material |
WO2017049066A1 (en) * | 2015-09-18 | 2017-03-23 | University Of Florida Research Foundation, Incorporated | Apparatus for culturing and interacting with a three-dimensional cell culture |
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US11931480B2 (en) | 2016-02-16 | 2024-03-19 | The Regents Of The University Of California | Microporous annealed particle gels and methods of use |
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US20220233454A1 (en) * | 2019-06-07 | 2022-07-28 | Likarda, LLC | Tunable degradation in hydrogel microparticles |
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US20220403309A1 (en) * | 2021-06-16 | 2022-12-22 | Upside Foods, Inc. | Plant fat-based scaffolds for the growth of cell-based meats and methods of making such products |
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CN114099369A (en) * | 2021-11-19 | 2022-03-01 | 佐藤生物医药(江苏)有限公司 | Nanoparticle composite hydrogel, preparation method thereof and application of nanoparticle composite hydrogel in preventing alopecia and growing hair |
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CN114410574B (en) * | 2022-03-24 | 2024-02-06 | 烟台鼎昊生物科技有限公司 | Preparation method of chondrocyte in-vitro three-dimensional culture system |
DE102022120500B3 (en) | 2022-08-15 | 2023-10-12 | FILK Freiberg Institute gGmbH | Method and device for producing hollow spheres from collagen and collagen derivatives and hollow spheres from collagen and gelatin |
CN115553469B (en) * | 2022-09-27 | 2023-10-03 | 六安益普罗科技有限公司 | Stomach mucosa-adhered probiotic slow-release microsphere, preparation method and medicine for preparing helicobacter pylori resisting or stomach mucositis relieving medicine |
CN116870243B (en) * | 2023-08-10 | 2024-01-19 | 广州创赛生物医用材料有限公司 | Hydrogel with hemostatic and anti-inflammatory effects and preparation method and application thereof |
CN117547554B (en) * | 2024-01-12 | 2024-05-14 | 山东康根源生物集团有限公司 | Mesenchymal stem cell repair preparation and preparation method thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4798786A (en) * | 1982-05-06 | 1989-01-17 | Stolle Research And Development Corporation | Living cells encapsulated in crosslinked protein |
DE10042484A1 (en) * | 2000-08-29 | 2002-03-28 | Merck Patent Gmbh | Preparing human cartilage implants, useful for repairing damaged joints, comprises culturing autologous chondrocytes in alginate gel at reduced oxygen partial pressure |
EP2229147A2 (en) * | 2007-12-03 | 2010-09-22 | The Johns Hopkins University | Methods of synthesis and use of chemospheres |
EP2429600B1 (en) * | 2009-05-15 | 2017-09-06 | Nanyang Technological University | Composition for manufacturing a scaffold for tissue engineering, and a method of making it |
-
2013
- 2013-07-26 WO PCT/SG2013/000312 patent/WO2014025312A1/en active Application Filing
- 2013-07-26 US US14/420,278 patent/US9974886B2/en active Active
- 2013-07-26 SG SG11201500188YA patent/SG11201500188YA/en unknown
- 2013-07-26 EP EP13828142.3A patent/EP2882465B1/en not_active Not-in-force
- 2013-07-26 SG SG10201700973YA patent/SG10201700973YA/en unknown
- 2013-07-26 CN CN201380042205.XA patent/CN104582747B/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2014025312A1 (en) | 2014-02-13 |
CN104582747B (en) | 2016-12-21 |
EP2882465B1 (en) | 2019-05-08 |
SG11201500188YA (en) | 2015-02-27 |
CN104582747A (en) | 2015-04-29 |
US9974886B2 (en) | 2018-05-22 |
US20150217024A1 (en) | 2015-08-06 |
EP2882465A4 (en) | 2016-04-06 |
EP2882465A1 (en) | 2015-06-17 |
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