SG10201500298PA - Inhibitors of flaviviridae viruses - Google Patents

Inhibitors of flaviviridae viruses

Info

Publication number
SG10201500298PA
SG10201500298PA SG10201500298PA SG10201500298PA SG10201500298PA SG 10201500298P A SG10201500298P A SG 10201500298PA SG 10201500298P A SG10201500298P A SG 10201500298PA SG 10201500298P A SG10201500298P A SG 10201500298PA SG 10201500298P A SG10201500298P A SG 10201500298PA
Authority
SG
Singapore
Prior art keywords
inhibitors
flaviviridae viruses
flaviviridae
viruses
Prior art date
Application number
SG10201500298PA
Other languages
English (en)
Inventor
Eda Canales
Michael O'neil Hanrahan Clarke
Scott E Lazerwith
Willard Lew
Philip Anthony Morganelli
William J Watkins
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43538203&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201500298P(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of SG10201500298PA publication Critical patent/SG10201500298PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SG10201500298PA 2010-01-15 2011-01-14 Inhibitors of flaviviridae viruses SG10201500298PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29557610P 2010-01-15 2010-01-15
US35348110P 2010-06-10 2010-06-10

Publications (1)

Publication Number Publication Date
SG10201500298PA true SG10201500298PA (en) 2015-03-30

Family

ID=43538203

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201500298PA SG10201500298PA (en) 2010-01-15 2011-01-14 Inhibitors of flaviviridae viruses
SG2012051181A SG182475A1 (en) 2010-01-15 2011-01-14 Inhibitors of flaviviridae viruses

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2012051181A SG182475A1 (en) 2010-01-15 2011-01-14 Inhibitors of flaviviridae viruses

Country Status (27)

Country Link
US (2) US8513298B2 (fr)
EP (2) EP3219713A1 (fr)
JP (2) JP5868872B2 (fr)
KR (1) KR101727776B1 (fr)
CN (1) CN102712633B (fr)
AP (1) AP3576A (fr)
AR (1) AR080001A1 (fr)
AU (1) AU2011205744B2 (fr)
BR (1) BR112012017382A2 (fr)
CA (1) CA2785567C (fr)
CL (1) CL2012001960A1 (fr)
CR (1) CR20120417A (fr)
EA (1) EA021196B1 (fr)
EC (1) ECSP12012104A (fr)
ES (1) ES2626150T3 (fr)
IL (1) IL220545B (fr)
MX (1) MX2012008211A (fr)
NZ (1) NZ600817A (fr)
PE (1) PE20130281A1 (fr)
PL (1) PL2523950T3 (fr)
PT (1) PT2523950T (fr)
SG (2) SG10201500298PA (fr)
SI (1) SI2523950T1 (fr)
TW (1) TWI491609B (fr)
UY (1) UY33183A (fr)
WO (1) WO2011088345A1 (fr)
ZA (1) ZA201205248B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2427342T3 (es) * 2009-07-21 2013-10-30 Gilead Sciences, Inc. Ácidos 5-alquiniltien-2-ilcarboxílicos como inhibidores de virus de los Flaviviridae
WO2011031669A1 (fr) 2009-09-09 2011-03-17 Gilead Sciences, Inc. Inhibiteurs de virus de la famille des flaviviridae
JP5777223B2 (ja) 2010-01-15 2015-09-09 ギリアード サイエンシーズ， インコーポレイテッド フラビウイルス科ウイルスのインヒビター
CN102712633B (zh) 2010-01-15 2015-07-29 吉里德科学公司 黄病毒科病毒的抑制剂
US20130273005A1 (en) * 2010-12-20 2013-10-17 Gilead Sciences, Inc. Methods for treating hcv
DE102011003295A1 (de) * 2011-01-28 2012-08-02 Kiekert Ag Kraftfahrzeugschloss
US8741946B2 (en) 2011-07-13 2014-06-03 Gilead Sciences, Inc. Inhibitors of flaviviridae viruses
NZ623396A (en) * 2011-09-16 2016-07-29 Gilead Pharmasset Llc Methods for treating hcv
CN103087052A (zh) * 2011-10-31 2013-05-08 上海壹志医药科技有限公司 噻吩衍生物及其药物用途
JP6209601B2 (ja) * 2012-06-08 2017-10-04 ギリアード サイエンシーズ， インコーポレイテッド フラビウイルス科ウイルスの大環状阻害剤
ES2656087T3 (es) 2012-06-08 2018-02-23 Gilead Sciences, Inc. Inhibidores macrocíclicos de virus Flaviviridae
AR091279A1 (es) 2012-06-08 2015-01-21 Gilead Sciences Inc Inhibidores macrociclicos de virus flaviviridae
US8841340B2 (en) 2012-08-17 2014-09-23 Gilead Sciences, Inc. Solid forms of an antiviral compound
US8927741B2 (en) 2012-08-17 2015-01-06 Gilead Sciences, Inc. Synthesis of an antiviral compound
US8759544B2 (en) 2012-08-17 2014-06-24 Gilead Sciences, Inc. Synthesis of an antiviral compound
LT2950786T (lt) 2013-01-31 2020-03-10 Gilead Pharmasset Llc Dviejų antivirusinių junginių preparatų kompozicija
WO2016065248A1 (fr) 2014-10-23 2016-04-28 Complete Genomics, Inc. Séquençage de confinement de signal (sc) et analogues de nucléotides utiles pour le séquençage de confinement de signal
KR20170123308A (ko) 2014-12-26 2017-11-07 에모리 유니버시티 Ｎ4-하이드록시시티딘, 이와 관련된 유도체 및 이의 항 바이러스적 용도
US10328061B2 (en) 2016-05-02 2019-06-25 Florida State University Research Foundation, Inc. Treatment of Zika virus infections using alpha-glucosidase inhibitors
CN109562107A (zh) 2016-05-10 2019-04-02 C4医药公司 用于靶蛋白降解的杂环降解决定子体
CN109562113A (zh) 2016-05-10 2019-04-02 C4医药公司 用于靶蛋白降解的螺环降解决定子体
EP3455218A4 (fr) 2016-05-10 2019-12-18 C4 Therapeutics, Inc. Dégronimères de type glutarimide liés au carbone c3 pour la dégradation de protéines cibles
CN116731101A (zh) 2016-06-01 2023-09-12 雅斯娜 用于治疗多种疾病的n-己酸-l-酪氨酸-l-异亮氨酸-(6)-氨基己酰胺的衍生物
BR122022008466B1 (pt) 2017-12-07 2023-12-05 Emory University Uso de um composto
CN108096562B (zh) * 2017-12-25 2021-05-11 武汉百药联科科技有限公司 20s蛋白酶体抑制剂在制备治疗日本乙型脑炎病毒感染的药物中的用途
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US743729A (en) * 1903-03-02 1903-11-10 William Clark Kirk Work-support for lathes.
US3533088A (en) * 1967-10-31 1970-10-06 Rca Corp Control circuit for memory
US4714839A (en) * 1986-03-27 1987-12-22 Advanced Micro Devices, Inc. Control circuit for disabling or enabling the provision of redundancy
US4721868A (en) * 1986-09-23 1988-01-26 Advanced Micro Devices, Inc. IC input circuitry programmable for realizing multiple functions from a single input
JPH02146195A (ja) * 1988-11-28 1990-06-05 Nec Corp 半導体記憶装置
JPH03214500A (ja) * 1990-01-18 1991-09-19 Sony Corp メモリ装置
JP2575919B2 (ja) * 1990-03-22 1997-01-29 株式会社東芝 半導体記憶装置の冗長回路
US5959445A (en) * 1995-09-29 1999-09-28 Intel Corporation Static, high-sensitivity, fuse-based storage cell
US5861421A (en) 1995-12-21 1999-01-19 Smithkline Beecham Corporation 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds
US6037799A (en) * 1995-12-29 2000-03-14 Stmicroelectronics, Inc. Circuit and method for selecting a signal
US20020002199A1 (en) * 1998-03-12 2002-01-03 Lone Jeppesen Modulators of protein tyrosine phosphatases (ptpases)
US20050119332A1 (en) * 1998-03-12 2005-06-02 Lone Jeppesen Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases)
US6175261B1 (en) * 1999-01-07 2001-01-16 Texas Instruments Incorporated Fuse cell for on-chip trimming
US6275063B1 (en) * 1999-08-24 2001-08-14 Micron Technology, Inc. Method and apparatus for limited reprogrammability of fuse options using one-time programmable elements
US6353336B1 (en) * 2000-03-24 2002-03-05 Cypress Semiconductor Corp. Electrical ID method for output driver
EP1395571A1 (fr) * 2001-06-11 2004-03-10 Shire Biochem Inc. Composes et methodes de traitement ou de prevention d'infections a i flavivirus /i
AP1753A (en) * 2001-06-11 2007-07-18 Shire Biochem Inc Thiophene derivatives as antiviral agents for flavvivirus infection
KR100481179B1 (ko) * 2002-09-10 2005-04-07 삼성전자주식회사 퓨즈를 구비한 회로 및 이를 이용한 반도체 장치
JP3884374B2 (ja) * 2002-12-06 2007-02-21 株式会社東芝 半導体装置
KR101058696B1 (ko) * 2002-12-10 2011-08-22 바이로켐 파마 인코포레이티드 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법
AU2003291885A1 (en) 2002-12-10 2004-06-30 Virochem Pharma Inc. Compounds and methods for the treatment or prevention of flavivirus infections
KR100569585B1 (ko) * 2003-12-05 2006-04-10 주식회사 하이닉스반도체 내부 전원 드라이버 제어 회로
DE10359791A1 (de) * 2003-12-19 2005-07-21 Bayer Healthcare Ag Substituierte Thiophene
US7521473B2 (en) * 2004-02-25 2009-04-21 Wyeth Inhibitors of protein tyrosine phosphatase 1B
US7470701B2 (en) 2004-03-30 2008-12-30 Novartis Vaccines And Diagnostics, Inc. Substituted 2,5-heterocyclic derivatives
DE102005028077A1 (de) 2004-12-22 2006-07-13 Aicuris Gmbh & Co. Kg Alkinyl-substituierte Thiophene
DE102004061746A1 (de) 2004-12-22 2006-07-06 Bayer Healthcare Ag Alkinyl-substituierte Thiophene
ES2415742T3 (es) * 2005-05-13 2013-07-26 Vertex Pharmaceuticals (Canada) Incorporated Compuestos y procedimientos para el tratamiento o prevención de infecciones por flavivirus
CN101501215A (zh) 2005-07-07 2009-08-05 阿什洛米克斯控股有限公司 用于诊断内毒素血症的多核苷酸标记基因及它们的表达
GB0602046D0 (en) 2006-02-01 2006-03-15 Smithkline Beecham Corp Compounds
KR20080096670A (ko) 2006-02-15 2008-10-31 사노피-아벤티스 신규한 아미노 알콜-치환된 아릴티에노피리미디논, 이의 제조 방법 및 약제로서 이의 용도
EA201101492A1 (ru) * 2006-11-15 2012-09-28 Вирокем Фарма Инк. Аналоги тиофена для лечения или предупреждения флавивирусных инфекций
WO2008059042A1 (fr) * 2006-11-17 2008-05-22 Smithkline Beecham Corporation Dérivés du 2-carboxy thiophène en tant qu'agents anti-viraux
KR20110098779A (ko) 2008-12-03 2011-09-01 프레시디오 파마슈티칼스, 인코포레이티드 Ｈｃｖ ｎｓ5ａ의 억제제
ES2427342T3 (es) * 2009-07-21 2013-10-30 Gilead Sciences, Inc. Ácidos 5-alquiniltien-2-ilcarboxílicos como inhibidores de virus de los Flaviviridae
WO2011031669A1 (fr) 2009-09-09 2011-03-17 Gilead Sciences, Inc. Inhibiteurs de virus de la famille des flaviviridae
WO2011068715A1 (fr) 2009-11-25 2011-06-09 Vertex Pharmaceuticals Incorporated Dérivés d'acide 5-alcynyl-thiophène-2-carboxylique et leur utilisation pour traiter ou prévenir des infections à flavivirus
JP5777223B2 (ja) * 2010-01-15 2015-09-09 ギリアード サイエンシーズ， インコーポレイテッド フラビウイルス科ウイルスのインヒビター
CN102712633B (zh) 2010-01-15 2015-07-29 吉里德科学公司 黄病毒科病毒的抑制剂
EP2585447A2 (fr) 2010-06-28 2013-05-01 Vertex Pharmaceuticals Incorporated Composés et méthodes pour le traitement ou la prévention d'infections par flavivirus
US8741946B2 (en) 2011-07-13 2014-06-03 Gilead Sciences, Inc. Inhibitors of flaviviridae viruses

Also Published As

Publication number Publication date
PE20130281A1 (es) 2013-03-08
ECSP12012104A (es) 2012-09-28
ES2626150T3 (es) 2017-07-24
ZA201205248B (en) 2013-03-27
AP2012006414A0 (en) 2012-08-31
CA2785567C (fr) 2018-03-27
EA201290576A1 (ru) 2013-01-30
UY33183A (es) 2011-08-31
TWI491609B (zh) 2015-07-11
US20130315861A1 (en) 2013-11-28
PT2523950T (pt) 2017-06-01
AU2011205744A1 (en) 2012-07-26
JP2013517291A (ja) 2013-05-16
SI2523950T1 (sl) 2017-06-30
PL2523950T3 (pl) 2017-09-29
KR101727776B1 (ko) 2017-04-17
TW201134822A (en) 2011-10-16
EP2523950A1 (fr) 2012-11-21
EP2523950B1 (fr) 2017-03-15
US20110178129A1 (en) 2011-07-21
US9321753B2 (en) 2016-04-26
CN102712633A (zh) 2012-10-03
CA2785567A1 (fr) 2011-07-21
JP2016041732A (ja) 2016-03-31
MX2012008211A (es) 2012-08-08
CL2012001960A1 (es) 2012-10-26
IL220545B (en) 2018-02-28
CR20120417A (es) 2012-11-30
JP5868872B2 (ja) 2016-02-24
EA021196B1 (ru) 2015-04-30
KR20120101733A (ko) 2012-09-14
US8513298B2 (en) 2013-08-20
NZ600817A (en) 2014-08-29
EP3219713A1 (fr) 2017-09-20
AP3576A (en) 2016-02-08
AU2011205744B2 (en) 2015-06-25
IL220545A0 (en) 2012-08-30
AR080001A1 (es) 2012-03-07
CN102712633B (zh) 2015-07-29
SG182475A1 (en) 2012-08-30
BR112012017382A2 (pt) 2017-12-05
WO2011088345A1 (fr) 2011-07-21

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