SG10201406839VA - Benzazepine compound - Google Patents

Benzazepine compound

Info

Publication number
SG10201406839VA
SG10201406839VA SG10201406839VA SG10201406839VA SG10201406839VA SG 10201406839V A SG10201406839V A SG 10201406839VA SG 10201406839V A SG10201406839V A SG 10201406839VA SG 10201406839V A SG10201406839V A SG 10201406839VA SG 10201406839V A SG10201406839V A SG 10201406839VA
Authority
SG
Singapore
Prior art keywords
benzazepine compound
group
salt
present
compound
Prior art date
Application number
SG10201406839VA
Other languages
English (en)
Inventor
Keizo Kan
Tadaaki Ohtani
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of SG10201406839VA publication Critical patent/SG10201406839VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Studio Devices (AREA)
SG10201406839VA 2009-10-26 2010-10-25 Benzazepine compound SG10201406839VA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009245434 2009-10-26

Publications (1)

Publication Number Publication Date
SG10201406839VA true SG10201406839VA (en) 2014-12-30

Family

ID=43921941

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201406839VA SG10201406839VA (en) 2009-10-26 2010-10-25 Benzazepine compound

Country Status (16)

Country Link
US (1) US8940727B2 (ja)
EP (1) EP2495236A4 (ja)
JP (1) JP5717645B2 (ja)
KR (1) KR20120092139A (ja)
CN (3) CN104447555A (ja)
AU (1) AU2010312651A1 (ja)
BR (1) BR112012009784A2 (ja)
CA (1) CA2778756A1 (ja)
CO (1) CO6481003A2 (ja)
EA (1) EA022253B1 (ja)
IL (1) IL219132A0 (ja)
IN (1) IN2012DN03343A (ja)
MX (1) MX2012004843A (ja)
SG (1) SG10201406839VA (ja)
WO (1) WO2011052519A1 (ja)
ZA (1) ZA201202640B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها
WO2019003433A1 (ja) * 2017-06-30 2019-01-03 大塚製薬株式会社 ベンゾアゼピン誘導体
TW201938171A (zh) 2017-12-15 2019-10-01 匈牙利商羅特格登公司 作為血管升壓素Ｖ１ａ受體拮抗劑之三環化合物
HU231206B1 (hu) 2017-12-15 2021-10-28 Richter Gedeon Nyrt. Triazolobenzazepinek
JP6868089B2 (ja) 2018-12-28 2021-05-12 大塚製薬株式会社 医薬
CN112851583B (zh) * 2021-01-19 2023-09-08 徐州医科大学 新型苯并氮杂䓬类化合物、组合物及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2905909B2 (ja) 1991-04-19 1999-06-14 大塚製薬株式会社 バソプレシン拮抗剤
US5258510A (en) * 1989-10-20 1993-11-02 Otsuka Pharma Co Ltd Benzoheterocyclic compounds
US5753677A (en) 1989-10-20 1998-05-19 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
DK0450097T3 (da) 1989-10-20 1996-05-20 Otsuka Pharma Co Ltd Benzoheterocykliske forbindelser
ES2198418T3 (es) 1993-07-21 2004-02-01 Yamanouchi Pharmaceutical Co. Ltd. Derivado de la benzazepina de fusion y composicion farmaceutica que incluye este derivado.
BRPI0615973A2 (pt) * 2005-07-29 2011-05-31 Concert Pharmaceuticals Inc novos derivados de benzo [d] [1,3] - dioxol
CN101516879A (zh) * 2006-06-05 2009-08-26 奥斯拜客斯制药有限公司 具有催眠作用的取代的咪唑并吡啶化合物的制备及用途
EP2081893B1 (en) * 2006-10-19 2011-03-23 Auspex Pharmaceuticals, Inc. Substituted indoles
TWI459947B (zh) * 2007-06-26 2014-11-11 Otsuka Pharma Co Ltd 苯并氮呯化合物及藥學製劑
WO2009117144A1 (en) 2008-03-20 2009-09-24 Concert Pharmaceuticals, Inc. Benzazepine compounds

Also Published As

Publication number Publication date
EA201290228A1 (ru) 2012-12-28
JPWO2011052519A1 (ja) 2013-03-21
EA022253B1 (ru) 2015-11-30
CN104447555A (zh) 2015-03-25
AU2010312651A1 (en) 2012-05-03
ZA201202640B (en) 2013-06-26
CN104829531A (zh) 2015-08-12
JP5717645B2 (ja) 2015-05-13
CO6481003A2 (es) 2012-07-16
US8940727B2 (en) 2015-01-27
CN102753530A (zh) 2012-10-24
MX2012004843A (es) 2012-05-29
IL219132A0 (en) 2012-06-28
BR112012009784A2 (pt) 2016-05-17
EP2495236A1 (en) 2012-09-05
EP2495236A4 (en) 2013-03-27
CN102753530B (zh) 2015-06-17
KR20120092139A (ko) 2012-08-20
WO2011052519A1 (ja) 2011-05-05
CA2778756A1 (en) 2011-05-05
IN2012DN03343A (ja) 2015-10-23
US20130131045A1 (en) 2013-05-23

Similar Documents

Publication Publication Date Title
MY168201A (en) Agricultural And Horticultural Fungicidal Composition
MX2009010071A (es) Derivados de aril isoxazolina insecticidas.
RS54386B1 (en) ANTIVIRAL UNITS
MA35452B1 (fr) 3-pyrimidin-4-yl-oxazolidin-2-ones comme inhibiteurs d'idh mutante
TW200612958A (en) Substituted imidazole derivatives
RS54123B1 (en) THERAPEUTIC COMBINATION CONTAINING DOLUTEGRAVIR, ABACAVIR AND LAMIVUDINE
MX2012007060A (es) Compuesto heterociclico conteniendo nitrogeno y fungicida para el uso en agricultura y jardineria.
MX2011008176A (es) Derivados de 3,3'-espiroindolinona como agentes anticancerigenos.
RS54207B1 (en) CONDENSED IMIDAZOLYLIMIDAZOLES AS ANTIVIRAL COMPOUNDS
MX2012009186A (es) Pirrolidina-2-carboxamidas sustituidas.
RS53301B (en) TIOACETATE COMPOUNDS, COMPOSITIONS AND USE PROCEDURES
MY152972A (en) Azabicyclo compound and salt thereof
MX2010007952A (es) Arilpirrolinas insecticidas.
WO2008108378A3 (en) Bicyclic oxomorpholine derivative
MY183312A (en) Pharmaceutical formulation
RS54730B1 (sr) Inhibitori beta sekretaze
TN2009000287A1 (en) Cyclized derivatives as eg-5inhibitors
UA108510C2 (en) Cyclopropane compound
WO2011039735A3 (en) Compounds with ddx3 inhibitory activity and uses thereof
MX2013000295A (es) Procedimiento de preparacion de un inhibidor especifico de la trombina.
MY147188A (en) Substituted imidazole compounds as ksp inhibitors
GEP20125637B (en) Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them
SG10201406839VA (en) Benzazepine compound
PH12018502012A1 (en) Griseofulvin compound
IN2014CN04449A (ja)