MX2012004843A - Compuesto de benzazepina. - Google Patents

Compuesto de benzazepina.

Info

Publication number
MX2012004843A
MX2012004843A MX2012004843A MX2012004843A MX2012004843A MX 2012004843 A MX2012004843 A MX 2012004843A MX 2012004843 A MX2012004843 A MX 2012004843A MX 2012004843 A MX2012004843 A MX 2012004843A MX 2012004843 A MX2012004843 A MX 2012004843A
Authority
MX
Mexico
Prior art keywords
frame rate
imaging
image
moving images
still image
Prior art date
Application number
MX2012004843A
Other languages
English (en)
Inventor
Keizo Kan
Tadaaki Ohtani
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Priority claimed from PCT/JP2010/006887 external-priority patent/WO2011065000A1/ja
Publication of MX2012004843A publication Critical patent/MX2012004843A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Un objetivo de la presente invención es proporcionar un compuesto novedoso de benzazepina o una sal del mismo, que tiene excelente actividad antagónica de vasopresina; el compuesto de benzazepina o una sal del mismo de la presente invención está representado por la Fórmula (1): (Ver Formula) en donde R1, R2 y R5 pueden ser el mismo o diferente y cada uno representa H o D; y R3 y R4 representan cada uno un grupo alquilo de C1-6, un grupo deuteroalquilo de C1-6, o un grupo perdeuteroalquilo de C1-6.
MX2012004843A 2009-10-26 2010-11-25 Compuesto de benzazepina. MX2012004843A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009245434 2009-10-26
PCT/JP2010/006887 WO2011065000A1 (ja) 2009-11-26 2010-11-25 電子カメラ

Publications (1)

Publication Number Publication Date
MX2012004843A true MX2012004843A (es) 2012-05-29

Family

ID=43921941

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012004843A MX2012004843A (es) 2009-10-26 2010-11-25 Compuesto de benzazepina.

Country Status (16)

Country Link
US (1) US8940727B2 (es)
EP (1) EP2495236A4 (es)
JP (1) JP5717645B2 (es)
KR (1) KR20120092139A (es)
CN (3) CN104447555A (es)
AU (1) AU2010312651A1 (es)
BR (1) BR112012009784A2 (es)
CA (1) CA2778756A1 (es)
CO (1) CO6481003A2 (es)
EA (1) EA022253B1 (es)
IL (1) IL219132A0 (es)
IN (1) IN2012DN03343A (es)
MX (1) MX2012004843A (es)
SG (1) SG10201406839VA (es)
WO (1) WO2011052519A1 (es)
ZA (1) ZA201202640B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها
WO2019003433A1 (ja) * 2017-06-30 2019-01-03 大塚製薬株式会社 ベンゾアゼピン誘導体
TW201938171A (zh) 2017-12-15 2019-10-01 匈牙利商羅特格登公司 作為血管升壓素Ｖ１ａ受體拮抗劑之三環化合物
HU231206B1 (hu) 2017-12-15 2021-10-28 Richter Gedeon Nyrt. Triazolobenzazepinek
JP6868089B2 (ja) 2018-12-28 2021-05-12 大塚製薬株式会社 医薬
CN112851583B (zh) * 2021-01-19 2023-09-08 徐州医科大学 新型苯并氮杂䓬类化合物、组合物及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753677A (en) * 1989-10-20 1998-05-19 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
ES2089033T3 (es) 1989-10-20 1996-10-01 Otsuka Pharma Co Ltd Compuestos benzoheterociclicos.
JP2905909B2 (ja) * 1991-04-19 1999-06-14 大塚製薬株式会社 バソプレシン拮抗剤
US5258510A (en) * 1989-10-20 1993-11-02 Otsuka Pharma Co Ltd Benzoheterocyclic compounds
CA2167673C (en) 1993-07-21 2004-09-21 Akihiro Tanaka Condensed benzazepine derivative and pharmaceutical composition thereof
CN101273024A (zh) * 2005-07-29 2008-09-24 康瑟特制药公司 新颖苯并[d][1,3]-二氧杂环戊烯衍生物
BRPI0711491A2 (pt) * 2006-06-05 2012-07-10 Auspex Pharmaceuticals Inc composição, método de tratamento de um mamìfero que sofre uma doença ou de uma condição que envolve um receptor de benzodiazepina e composição farmacêutica"
CN101687788A (zh) * 2006-10-19 2010-03-31 奥斯拜客斯制药有限公司 取代的吲哚
TWI459947B (zh) * 2007-06-26 2014-11-11 Otsuka Pharma Co Ltd 苯并氮呯化合物及藥學製劑
WO2009117144A1 (en) * 2008-03-20 2009-09-24 Concert Pharmaceuticals, Inc. Benzazepine compounds

Also Published As

Publication number Publication date
CA2778756A1 (en) 2011-05-05
SG10201406839VA (en) 2014-12-30
WO2011052519A1 (ja) 2011-05-05
BR112012009784A2 (pt) 2016-05-17
CN102753530B (zh) 2015-06-17
US20130131045A1 (en) 2013-05-23
US8940727B2 (en) 2015-01-27
EA201290228A1 (ru) 2012-12-28
JP5717645B2 (ja) 2015-05-13
IL219132A0 (en) 2012-06-28
CN104829531A (zh) 2015-08-12
CN104447555A (zh) 2015-03-25
ZA201202640B (en) 2013-06-26
EA022253B1 (ru) 2015-11-30
IN2012DN03343A (es) 2015-10-23
JPWO2011052519A1 (ja) 2013-03-21
KR20120092139A (ko) 2012-08-20
CO6481003A2 (es) 2012-07-16
EP2495236A1 (en) 2012-09-05
CN102753530A (zh) 2012-10-24
EP2495236A4 (en) 2013-03-27
AU2010312651A1 (en) 2012-05-03

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