SG10201401516XA - Pcsk9 vaccine - Google Patents
Pcsk9 vaccineInfo
- Publication number
- SG10201401516XA SG10201401516XA SG10201401516XA SG10201401516XA SG10201401516XA SG 10201401516X A SG10201401516X A SG 10201401516XA SG 10201401516X A SG10201401516X A SG 10201401516XA SG 10201401516X A SG10201401516X A SG 10201401516XA SG 10201401516X A SG10201401516X A SG 10201401516XA
- Authority
- SG
- Singapore
- Prior art keywords
- pcsk9 vaccine
- pcsk9
- vaccine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/005—Trypanosoma antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21061—Kexin (3.4.21.61), i.e. proprotein convertase subtilisin/kexin type 9
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23954109P | 2009-09-03 | 2009-09-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201401516XA true SG10201401516XA (en) | 2014-10-30 |
Family
ID=43413463
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201401516XA SG10201401516XA (en) | 2009-09-03 | 2010-08-23 | Pcsk9 vaccine |
| SG2012010740A SG178447A1 (en) | 2009-09-03 | 2010-08-23 | Pcsk9 vaccine |
| SG10201401515YA SG10201401515YA (en) | 2009-09-03 | 2010-08-23 | PCSK9 vaccine |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2012010740A SG178447A1 (en) | 2009-09-03 | 2010-08-23 | Pcsk9 vaccine |
| SG10201401515YA SG10201401515YA (en) | 2009-09-03 | 2010-08-23 | PCSK9 vaccine |
Country Status (30)
| Country | Link |
|---|---|
| US (4) | US8889144B2 (tr) |
| EP (3) | EP2865752A1 (tr) |
| JP (5) | JP2013503623A (tr) |
| KR (3) | KR101660578B1 (tr) |
| CN (3) | CN104548089B (tr) |
| AR (2) | AR078247A1 (tr) |
| AU (1) | AU2010290931B2 (tr) |
| BR (1) | BR112012004807A2 (tr) |
| CA (2) | CA2846746A1 (tr) |
| CO (1) | CO6501190A2 (tr) |
| DK (1) | DK2473605T3 (tr) |
| ES (1) | ES2670576T3 (tr) |
| HK (3) | HK1174056A1 (tr) |
| HU (1) | HUE037416T2 (tr) |
| IL (2) | IL218229A (tr) |
| MX (1) | MX2012002639A (tr) |
| MY (1) | MY163512A (tr) |
| NO (1) | NO2473605T3 (tr) |
| NZ (3) | NZ710626A (tr) |
| PE (3) | PE20121544A1 (tr) |
| PH (2) | PH12016500004A1 (tr) |
| PL (1) | PL2473605T3 (tr) |
| PT (1) | PT2473605T (tr) |
| RU (2) | RU2538162C2 (tr) |
| SA (3) | SA110310687B1 (tr) |
| SG (3) | SG10201401516XA (tr) |
| SI (1) | SI2473605T1 (tr) |
| TR (1) | TR201808222T4 (tr) |
| TW (1) | TWI400085B (tr) |
| WO (1) | WO2011027257A2 (tr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY178905A (en) | 2008-08-29 | 2020-10-22 | Oral Health Australia Pty Ltd | Prevention, treatment and diagnosis of p.gingivalis infection |
| EP2759306B1 (en) | 2008-12-09 | 2016-04-06 | Coley Pharmaceutical Group, Inc. | Immunostimulatory oligonucleotides |
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| GB201005005D0 (en) * | 2010-03-25 | 2010-05-12 | Angeletti P Ist Richerche Bio | New vaccine |
| US20140004142A1 (en) * | 2011-03-02 | 2014-01-02 | Pfizer Inc. | Pcsk9 vaccine |
| EP2532359A1 (en) | 2011-06-10 | 2012-12-12 | Affiris AG | CETP fragments |
| SI2570135T1 (sl) * | 2011-09-13 | 2016-05-31 | Affiris Ag | PCSK9 cepivo |
| US9255154B2 (en) | 2012-05-08 | 2016-02-09 | Alderbio Holdings, Llc | Anti-PCSK9 antibodies and use thereof |
| EP2703483A1 (en) | 2012-08-29 | 2014-03-05 | Affiris AG | PCSK9 peptide vaccine |
| ES2640320T3 (es) * | 2012-10-17 | 2017-11-02 | Glaxosmithkline Biologicals S.A. | Composición inmunogénica que comprende 1 o más conjugados de sacáridos capsulares de Streptococcus pneumoniae y un componente proteico que comprende proteína E y/o PilA de Haemophilus influenzae |
| US10058630B2 (en) * | 2012-10-22 | 2018-08-28 | Concievalve, Llc | Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis |
| US10117923B2 (en) | 2012-11-07 | 2018-11-06 | Vacplanta Limited | Production of an immunogen using a plant virus |
| US20150274784A1 (en) * | 2012-11-07 | 2015-10-01 | Vacplanta Limted | Production of an Immunogen Using a Plant Virus |
| TWI641382B (zh) * | 2013-01-31 | 2018-11-21 | 韓美藥品股份有限公司 | 於包含因子ｖｉｉ之組成物中使病毒失活之方法 |
| CN104043120B (zh) | 2013-03-13 | 2017-05-31 | 南京赛威信生物医药有限公司 | 乙型肝炎疫苗 |
| WO2015123291A1 (en) | 2014-02-11 | 2015-08-20 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Pcsk9 vaccine and methods of using the same |
| WO2015128287A1 (en) | 2014-02-28 | 2015-09-03 | Affiris Ag | Pcsk9 vaccines |
| CN104558199B (zh) * | 2014-09-05 | 2018-07-06 | 成都康弘生物科技有限公司 | 一种治疗高胆固醇血症的融合蛋白制备及其用途 |
| TWI655002B (zh) * | 2015-07-20 | 2019-04-01 | 碩騰服務有限責任公司 | 脂質體佐劑組合物 |
| KR20180063321A (ko) | 2015-10-19 | 2018-06-11 | 카딜라 핼쓰캐어 리미티드 | 신규 보조제 및 이를 함유하는 백신 조성물 |
| RU2734924C2 (ru) * | 2015-11-03 | 2020-10-26 | Аффирис Аг | Способ вакцинации против аутоантигена у пациента-человека |
| AU2017238817B2 (en) * | 2016-03-25 | 2023-12-21 | Funpep Co., Ltd. | Conjugate vaccine targeting a disease-causing biological protein |
| CA3026823A1 (en) * | 2016-06-24 | 2017-12-28 | F. Hoffmann-La Roche Ag | Compositions and methods for treating cardiovascular disease |
| CN106822881A (zh) * | 2016-12-09 | 2017-06-13 | 四川大学 | 一种针对pcsk9的抗高血脂蛋白疫苗 |
| CA3058567A1 (en) | 2017-04-13 | 2018-10-18 | Cadila Healthcare Limited | Novel peptide based pcsk9 vaccine |
| CN107488215A (zh) * | 2017-07-19 | 2017-12-19 | 邱志华 | 人前蛋白转化酶枯草溶菌素9免疫原性肽段及其载体疫苗 |
| WO2021001804A1 (en) * | 2019-07-04 | 2021-01-07 | Cadila Healthcare Limited | Angptl3 based vaccine for the treatment of liver disease |
| WO2021154947A1 (en) * | 2020-01-28 | 2021-08-05 | Ubi Ip Holdings | Peptide immunogens targeting pcsk9 and formulations thereof for prevention and treatment of pcsk9-mediated disorders |
| IL296071A (en) | 2020-03-01 | 2022-11-01 | Valneva Austria Gmbh | Sars-cov-2 virus vaccine with adjuvant cytidine-phosphoguanosine |
| WO2022147373A1 (en) * | 2020-12-31 | 2022-07-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Antibody-guided pcsk9-mimicking immunogens lacking 9-residue sequence overlap with human proteins |
| WO2023161526A1 (en) | 2022-02-28 | 2023-08-31 | Tridem Bioscience Gmbh & Co Kg | A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN |
| CN117327159A (zh) * | 2023-07-31 | 2024-01-02 | 杭州纽龙生物科技有限公司 | 一种蛋白a耐碱突变方法 |
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