SE9802938D0 - Improved stability for injection solutions - Google Patents

Improved stability for injection solutions

Info

Publication number
SE9802938D0
SE9802938D0 SE9802938A SE9802938A SE9802938D0 SE 9802938 D0 SE9802938 D0 SE 9802938D0 SE 9802938 A SE9802938 A SE 9802938A SE 9802938 A SE9802938 A SE 9802938A SE 9802938 D0 SE9802938 D0 SE 9802938D0
Authority
SE
Sweden
Prior art keywords
improved stability
injection solutions
package
rubber
sealed
Prior art date
Application number
SE9802938A
Other languages
English (en)
Swedish (sv)
Inventor
Anna Lundgren
Mats Sundgren
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9802938A priority Critical patent/SE9802938D0/xx
Publication of SE9802938D0 publication Critical patent/SE9802938D0/xx
Priority to ARP990104129 priority patent/AR033788A1/es
Priority to TW088114257A priority patent/TWI228987B/zh
Priority to HK01105969.5A priority patent/HK1035482B/en
Priority to NZ50998599A priority patent/NZ509985A/xx
Priority to AT99946504T priority patent/ATE262882T1/de
Priority to EP99946504A priority patent/EP1109526B1/en
Priority to AU58903/99A priority patent/AU754447C/en
Priority to SK282-2001A priority patent/SK285474B6/sk
Priority to SI9930585T priority patent/SI1109526T1/xx
Priority to TR200100679T priority patent/TR200100679T2/xx
Priority to ES99946504T priority patent/ES2217808T3/es
Priority to US09/423,185 priority patent/US6576245B1/en
Priority to DK99946504T priority patent/DK1109526T3/da
Priority to CA 2340238 priority patent/CA2340238C/en
Priority to KR1020017002618A priority patent/KR100614162B1/ko
Priority to ID20010430A priority patent/ID28015A/id
Priority to CZ2001743A priority patent/CZ2001743A3/cs
Priority to JP2000567167A priority patent/JP2002523184A/ja
Priority to PT99946504T priority patent/PT1109526E/pt
Priority to HU0104161A priority patent/HUP0104161A3/hu
Priority to EEP200100131A priority patent/EE04768B1/xx
Priority to DE1999616082 priority patent/DE69916082T2/de
Priority to IL14133399A priority patent/IL141333A0/xx
Priority to PCT/SE1999/001440 priority patent/WO2000012043A1/en
Priority to RU2001104425A priority patent/RU2224499C2/ru
Priority to CNB998101931A priority patent/CN1230141C/zh
Priority to BR9913261A priority patent/BR9913261A/pt
Priority to UA2001021045A priority patent/UA73282C2/uk
Priority to PL99346471A priority patent/PL195244B1/pl
Priority to MYPI9903750 priority patent/MY120822A/en
Priority to SA99200573A priority patent/SA99200573B1/ar
Priority to IL141333A priority patent/IL141333A/en
Priority to IS5845A priority patent/IS2230B/is
Priority to ZA200101590A priority patent/ZA200101590B/xx
Priority to NO20011032A priority patent/NO322292B1/no
Priority to US10/347,046 priority patent/US6660279B2/en
Priority to US10/687,540 priority patent/US6998136B2/en
Priority to US11/270,309 priority patent/US20060233778A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • A61J1/062Carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1468Containers characterised by specific material properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE9802938A 1998-09-01 1998-09-01 Improved stability for injection solutions SE9802938D0 (sv)

Priority Applications (39)

Application Number Priority Date Filing Date Title
SE9802938A SE9802938D0 (sv) 1998-09-01 1998-09-01 Improved stability for injection solutions
ARP990104129 AR033788A1 (es) 1998-09-01 1999-08-18 Envase primario, uso de un tapon o embolo de caucho que contiene caucho de bromobutilo para sellar el envase primario y procedimiento para la manufactura del envase primario
TW088114257A TWI228987B (en) 1998-09-01 1999-08-20 Improved stability for injection solutions
PL99346471A PL195244B1 (pl) 1998-09-01 1999-08-24 Postać niskocząsteczkowego peptydowego inhibitoratrombiny, zastosowanie gumowego korka lub tłoka isposób wytwarzania tej postaci
JP2000567167A JP2002523184A (ja) 1998-09-01 1999-08-24 注射溶液のための改良された安定性
HU0104161A HUP0104161A3 (en) 1998-09-01 1999-08-24 Improved stability for injection solutions, containing peptid-based thrombin inhibitor and process for preparation thereof
AT99946504T ATE262882T1 (de) 1998-09-01 1999-08-24 Verbesserte stabilität für injektionslösungen
EP99946504A EP1109526B1 (en) 1998-09-01 1999-08-24 Improved stability for injection solutions
AU58903/99A AU754447C (en) 1998-09-01 1999-08-24 Improved stability for injection solutions
SK282-2001A SK285474B6 (sk) 1998-09-01 1999-08-24 Primárne balenie obsahujúce vodný roztok na parenterálne podávanie a spôsob jeho výroby
SI9930585T SI1109526T1 (en) 1998-09-01 1999-08-24 Improved stability for injection solutions
TR200100679T TR200100679T2 (tr) 1998-09-01 1999-08-24 Enjeksiyon çözeltileri için arttırılmış kararlılık.
ES99946504T ES2217808T3 (es) 1998-09-01 1999-08-24 Estabilidad mejorada para disolucines inyectables.
US09/423,185 US6576245B1 (en) 1998-09-01 1999-08-24 Stability for injection solutions
DK99946504T DK1109526T3 (da) 1998-09-01 1999-08-24 Forbedret stabilitet for injektionsoplösninger
CA 2340238 CA2340238C (en) 1998-09-01 1999-08-24 Improved stability for injection solutions
KR1020017002618A KR100614162B1 (ko) 1998-09-01 1999-08-24 안정성이 개선된 주사액
ID20010430A ID28015A (id) 1998-09-01 1999-08-24 Peningkatan stabilitas larutan injeksi
CZ2001743A CZ2001743A3 (cs) 1998-09-01 1999-08-24 Primární obal a způsob jeho výroby
HK01105969.5A HK1035482B (en) 1998-09-01 1999-08-24 Improved stability for injection solutions
PT99946504T PT1109526E (pt) 1998-09-01 1999-08-24 Estabilidade melhorada para solucoes injectaveis
NZ50998599A NZ509985A (en) 1998-09-01 1999-08-24 Improved stability for injection solutions
EEP200100131A EE04768B1 (et) 1998-09-01 1999-08-24 Esmapakend ja meetod selle valmistamiseks
DE1999616082 DE69916082T2 (de) 1998-09-01 1999-08-24 Verbesserte stabilität für injektionslösungen
IL14133399A IL141333A0 (en) 1998-09-01 1999-08-24 Improved stability for injection solutions
PCT/SE1999/001440 WO2000012043A1 (en) 1998-09-01 1999-08-24 Improved stability for injection solutions
RU2001104425A RU2224499C2 (ru) 1998-09-01 1999-08-24 Повышение стабильности растворов для инъекций
CNB998101931A CN1230141C (zh) 1998-09-01 1999-08-24 提高注射液的稳定性
BR9913261A BR9913261A (pt) 1998-09-01 1999-08-24 Embalagem primária contendo uma solução aquosa para administração parenteral, uso de uma rolha ou êmbolo contendo borracha de bromobutila, e, processo para a manufatura de uma embalagem primária
UA2001021045A UA73282C2 (en) 1998-09-01 1999-08-24 Primary package of solution for injections, method for its manufacture, use of bromobutyl rubber for manufacturing stopper or plunger sealing primary package
MYPI9903750 MY120822A (en) 1998-09-01 1999-08-30 Stability for injection solutions
SA99200573A SA99200573B1 (ar) 1998-09-01 1999-09-14 ثبات محسن لمحاليل الحقن
IL141333A IL141333A (en) 1998-09-01 2001-02-08 Package for improved stability for injection solutions
IS5845A IS2230B (is) 1998-09-01 2001-02-15 Aukinn stöðugleiki lausna til inndælingar
ZA200101590A ZA200101590B (en) 1998-09-01 2001-02-26 Improved stability for injection solutions.
NO20011032A NO322292B1 (no) 1998-09-01 2001-02-28 Primaer emballasje inneholdende en vandig opplosning for parenteral administrasjon, fremgangsmate for fremstilling av emballasjen, og anvendelse av en gummiforsegling for denne
US10/347,046 US6660279B2 (en) 1998-09-01 2003-01-17 Stability for injection solutions
US10/687,540 US6998136B2 (en) 1998-09-01 2003-10-15 Stability for injection solutions
US11/270,309 US20060233778A1 (en) 1998-09-01 2005-11-08 Stability for injection solutions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9802938A SE9802938D0 (sv) 1998-09-01 1998-09-01 Improved stability for injection solutions

Publications (1)

Publication Number Publication Date
SE9802938D0 true SE9802938D0 (sv) 1998-09-01

Family

ID=20412436

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9802938A SE9802938D0 (sv) 1998-09-01 1998-09-01 Improved stability for injection solutions

Country Status (33)

Country Link
US (4) US6576245B1 (https=)
EP (1) EP1109526B1 (https=)
JP (1) JP2002523184A (https=)
KR (1) KR100614162B1 (https=)
CN (1) CN1230141C (https=)
AR (1) AR033788A1 (https=)
AT (1) ATE262882T1 (https=)
AU (1) AU754447C (https=)
BR (1) BR9913261A (https=)
CA (1) CA2340238C (https=)
CZ (1) CZ2001743A3 (https=)
DE (1) DE69916082T2 (https=)
DK (1) DK1109526T3 (https=)
EE (1) EE04768B1 (https=)
ES (1) ES2217808T3 (https=)
HU (1) HUP0104161A3 (https=)
ID (1) ID28015A (https=)
IL (2) IL141333A0 (https=)
IS (1) IS2230B (https=)
MY (1) MY120822A (https=)
NO (1) NO322292B1 (https=)
NZ (1) NZ509985A (https=)
PL (1) PL195244B1 (https=)
PT (1) PT1109526E (https=)
RU (1) RU2224499C2 (https=)
SA (1) SA99200573B1 (https=)
SE (1) SE9802938D0 (https=)
SK (1) SK285474B6 (https=)
TR (1) TR200100679T2 (https=)
TW (1) TWI228987B (https=)
UA (1) UA73282C2 (https=)
WO (1) WO2000012043A1 (https=)
ZA (1) ZA200101590B (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802938D0 (sv) * 1998-09-01 1998-09-01 Astra Ab Improved stability for injection solutions
US6462021B1 (en) 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
US7129233B2 (en) 2000-12-01 2006-10-31 Astrazeneca Ab Mandelic acid derivatives and their use as thrombin inhibitors
AR035216A1 (es) * 2000-12-01 2004-05-05 Astrazeneca Ab Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios
AR034517A1 (es) * 2001-06-21 2004-02-25 Astrazeneca Ab Formulacion farmaceutica
US6802828B2 (en) * 2001-11-23 2004-10-12 Duoject Medical Systems, Inc. System for filling and assembling pharmaceutical delivery devices
SE0201659D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab Modified release pharmaceutical formulation
SE0201661D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab New salts
AU2003302238A1 (en) 2002-12-03 2004-06-23 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
EP1594434B1 (en) * 2003-01-14 2016-09-07 Yeda Research and Development Co. Parenteral formulations of peptides for the treatment of systemic lupus erythematosus
KR100505557B1 (ko) * 2003-02-10 2005-08-03 조을룡 약병마개 제조용 고무 조성물
US7781424B2 (en) * 2003-05-27 2010-08-24 Astrazeneca Ab Modified release pharmaceutical formulation
US8476010B2 (en) 2003-07-10 2013-07-02 App Pharmaceuticals Llc Propofol formulations with non-reactive container closures
US7524354B2 (en) * 2005-07-07 2009-04-28 Research Foundation Of State University Of New York Controlled synthesis of highly monodispersed gold nanoparticles
US20070166187A1 (en) * 2006-01-18 2007-07-19 Song Jing F Stabilization of paricalcitol using chlorobutyl or chlorinated butyl stoppers
TW200827336A (en) * 2006-12-06 2008-07-01 Astrazeneca Ab New crystalline forms
US20090061000A1 (en) * 2007-08-31 2009-03-05 Astrazeneca Ab Pharmaceutical formulation use 030
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
CN103957966B (zh) * 2011-09-27 2017-09-29 贝克顿迪金森法国公司 等离子体处理过的硅油作为医用注射装置中的涂层的用途
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381779A (en) 1981-07-16 1983-05-03 Sterling Drug Inc. Deformable slidable piston to provide self-aspiration in hypodermic cartridge ampoules
DE69000716T2 (de) 1989-03-28 1993-07-22 Duphar Int Res Vorgefuellte injektionsvorrichtung mit einem fass, das mit einer fluessigen diazepam-formulierung gefuellt ist.
US5219328A (en) * 1990-01-03 1993-06-15 Cryolife, Inc. Fibrin sealant delivery method
SE9103612D0 (sv) 1991-12-04 1991-12-04 Astra Ab New peptide derivatives
SE9301916D0 (sv) 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
SE9402332D0 (sv) * 1994-07-01 1994-07-01 Pharmacia Ab Igf-1
SE9501472D0 (sv) 1995-04-21 1995-04-21 Pharmacia Ab Truncated IGF-I
SA96170106A (ar) 1995-07-06 2005-12-03 أسترا أكتيبولاج مشتقات حامض أميني جديدة
TWI238827B (en) 1995-12-21 2005-09-01 Astrazeneca Ab Prodrugs of thrombin inhibitors
SE9601556D0 (sv) * 1996-04-24 1996-04-24 Astra Ab New pharmaceutical formulation of a thrombin inhibitor for parenteral use
SE9802938D0 (sv) 1998-09-01 1998-09-01 Astra Ab Improved stability for injection solutions

Also Published As

Publication number Publication date
IS2230B (is) 2007-04-15
AR033788A1 (es) 2004-01-07
SK285474B6 (sk) 2007-02-01
NO20011032L (no) 2001-04-30
ATE262882T1 (de) 2004-04-15
IL141333A (en) 2006-07-05
SA99200573A (ar) 2005-12-03
PL195244B1 (pl) 2007-08-31
TWI228987B (en) 2005-03-11
PL346471A1 (en) 2002-02-11
NZ509985A (en) 2002-12-20
CA2340238C (en) 2009-01-06
DE69916082D1 (de) 2004-05-06
JP2002523184A (ja) 2002-07-30
EP1109526B1 (en) 2004-03-31
PT1109526E (pt) 2004-07-30
SK2822001A3 (en) 2001-08-06
KR100614162B1 (ko) 2006-08-25
US6998136B2 (en) 2006-02-14
CA2340238A1 (en) 2000-03-09
HUP0104161A2 (hu) 2002-04-29
NO20011032D0 (no) 2001-02-28
EE200100131A (et) 2002-06-17
RU2224499C2 (ru) 2004-02-27
ZA200101590B (en) 2002-05-27
UA73282C2 (en) 2005-07-15
MY120822A (en) 2005-11-30
CN1314804A (zh) 2001-09-26
WO2000012043A1 (en) 2000-03-09
AU754447B2 (en) 2002-11-14
NO322292B1 (no) 2006-09-11
BR9913261A (pt) 2001-05-22
IS5845A (is) 2001-02-15
SA99200573B1 (ar) 2006-09-20
AU5890399A (en) 2000-03-21
ES2217808T3 (es) 2004-11-01
DE69916082T2 (de) 2004-10-21
DK1109526T3 (da) 2004-07-05
TR200100679T2 (tr) 2001-07-23
CN1230141C (zh) 2005-12-07
EE04768B1 (et) 2007-02-15
HK1035482A1 (en) 2001-11-30
US20030190310A1 (en) 2003-10-09
AU754447C (en) 2006-10-19
EP1109526A1 (en) 2001-06-27
US20040235731A1 (en) 2004-11-25
CZ2001743A3 (cs) 2002-01-16
US6660279B2 (en) 2003-12-09
ID28015A (id) 2001-05-03
IL141333A0 (en) 2002-03-10
KR20010073070A (ko) 2001-07-31
US20060233778A1 (en) 2006-10-19
US6576245B1 (en) 2003-06-10
HUP0104161A3 (en) 2002-08-28

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