DE69000716T2 - Vorgefuellte injektionsvorrichtung mit einem fass, das mit einer fluessigen diazepam-formulierung gefuellt ist. - Google Patents

Vorgefuellte injektionsvorrichtung mit einem fass, das mit einer fluessigen diazepam-formulierung gefuellt ist.

Info

Publication number
DE69000716T2
DE69000716T2 DE9090200587T DE69000716T DE69000716T2 DE 69000716 T2 DE69000716 T2 DE 69000716T2 DE 9090200587 T DE9090200587 T DE 9090200587T DE 69000716 T DE69000716 T DE 69000716T DE 69000716 T2 DE69000716 T2 DE 69000716T2
Authority
DE
Germany
Prior art keywords
filled
barrel
injection device
formulation
diazepam formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE9090200587T
Other languages
English (en)
Other versions
DE69000716D1 (de
Inventor
Den Heuvel Johan Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duphar International Research BV
Original Assignee
Duphar International Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research BV filed Critical Duphar International Research BV
Publication of DE69000716D1 publication Critical patent/DE69000716D1/de
Application granted granted Critical
Publication of DE69000716T2 publication Critical patent/DE69000716T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/062—Carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M2005/3132—Syringe barrels having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
DE9090200587T 1989-03-28 1990-03-13 Vorgefuellte injektionsvorrichtung mit einem fass, das mit einer fluessigen diazepam-formulierung gefuellt ist. Expired - Fee Related DE69000716T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8900747 1989-03-28

Publications (2)

Publication Number Publication Date
DE69000716D1 DE69000716D1 (de) 1993-02-18
DE69000716T2 true DE69000716T2 (de) 1993-07-22

Family

ID=19854360

Family Applications (1)

Application Number Title Priority Date Filing Date
DE9090200587T Expired - Fee Related DE69000716T2 (de) 1989-03-28 1990-03-13 Vorgefuellte injektionsvorrichtung mit einem fass, das mit einer fluessigen diazepam-formulierung gefuellt ist.

Country Status (9)

Country Link
US (1) US5383864A (de)
EP (1) EP0390244B1 (de)
JP (1) JPH02283377A (de)
AT (1) ATE84205T1 (de)
CA (1) CA2012919A1 (de)
DE (1) DE69000716T2 (de)
DK (1) DK0390244T3 (de)
ES (1) ES2036885T3 (de)
IL (1) IL93881A (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU635631B2 (en) * 1991-01-15 1993-03-25 Astra Pharmaceuticals Pty Ltd Plastic syringe
NZ247392A (en) * 1992-04-30 1995-05-26 Takeda Chemical Industries Ltd Prefilled syringe containing two substances mixed before injection
US5364363A (en) * 1993-07-08 1994-11-15 Survival Technology, Inc. Rectal administrator
DE4332308C1 (de) * 1993-09-23 1994-09-29 Heraeus Kulzer Gmbh Spritze zum dosierten Abgeben von viskosen Werkstoffen, insbesondere von dentalen Werkstoffen
CA2164318C (en) * 1993-12-28 1999-12-07 Tetsuro Higashikawa Syringe
US5586975A (en) * 1994-02-18 1996-12-24 Takeda Chemical Industries. Ltd. Air and liquid tight container with a slidable gasket
JP3306796B2 (ja) * 1995-01-26 2002-07-24 大成化工株式会社 薬液が予備充填された注入筒向けガラスカートリッジ
FR2756811B1 (fr) * 1996-12-06 1999-02-05 Valois Dispositif de distribution de produit fluide du type bicomposant
SE9802938D0 (sv) * 1998-09-01 1998-09-01 Astra Ab Improved stability for injection solutions
US6840952B2 (en) * 2000-12-07 2005-01-11 Mark B. Saker Tissue tract sealing device
US20020139088A1 (en) * 2001-03-08 2002-10-03 Archie Woodworth Polymeric syringe body and stopper
EP1455864A2 (de) * 2001-11-02 2004-09-15 Meridian Medical Technologies, Inc. Medikamentenbehälter, medikamentausgabeset zur verabreichung von medikamenten und verpackungsverfahren dafür
GB0304823D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
US8476010B2 (en) 2003-07-10 2013-07-02 App Pharmaceuticals Llc Propofol formulations with non-reactive container closures
GB0414054D0 (en) 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
GB2453069B (en) 2004-11-22 2009-12-09 Intelliject Llc Devices,systems and methods for medicament delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
EP1843812A4 (de) 2005-02-01 2008-12-03 Intelliject Llc Vorrichtungen, systeme und verfahren zur medikamentenabgabe
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
WO2006109272A2 (en) * 2005-04-13 2006-10-19 Coeur Inc Syringe plunger jacket with expandable seal
US8007635B2 (en) 2005-05-02 2011-08-30 International Paper Company Lignocellulosic materials and the products made therefrom
US20070166187A1 (en) * 2006-01-18 2007-07-19 Song Jing F Stabilization of paricalcitol using chlorobutyl or chlorinated butyl stoppers
CN103316403B (zh) * 2006-06-30 2017-05-24 艾伯维生物技术有限公司 自动注射装置
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
US20100103765A1 (en) * 2008-10-24 2010-04-29 Hornbostel Marc D Liquid injector for silicon production
US8734390B2 (en) * 2009-09-30 2014-05-27 Terumo Kabushiki Kaisha Injection aid and medication syringe device
EP2667918B1 (de) 2011-01-24 2017-03-01 AbbVie Biotechnology Ltd Automatische injektionsvorrichtungen mit übersrpitzten griffflächen
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9173999B2 (en) 2011-01-26 2015-11-03 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
US9204914B2 (en) * 2012-01-27 2015-12-08 Kyphon Sarl Cement mixer and bone filler device
BR112014021644A2 (pt) 2012-03-02 2016-10-25 Abbvie Inc dispositivo automático de treinamento de injeção
US9522235B2 (en) 2012-05-22 2016-12-20 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
US9125805B2 (en) * 2012-06-27 2015-09-08 Xeris Pharmaceuticals, Inc. Stable formulations for parenteral injection of small molecule drugs
US20160144123A1 (en) * 2014-11-26 2016-05-26 John Berndt Syringe adapter
EP3025744A1 (de) 2014-11-28 2016-06-01 Sulzer Mixpac AG Vorrichtung und Verfahren zum Aufbewahren und Mischen von separaten Substanzen
EP3274021B1 (de) 2015-03-24 2024-02-14 Kaleo, Inc. Vorrichtungen und verfahren zur abgabe eines lyophilisierten medikaments
WO2017004345A1 (en) 2015-06-30 2017-01-05 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
US9579453B1 (en) 2016-02-18 2017-02-28 Chalbourne Brasington Two-step auto-injection device
US10688244B2 (en) 2016-12-23 2020-06-23 Kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
WO2018175135A1 (en) 2017-03-21 2018-09-27 International Paper Company Odor control pulp composition
US10245381B2 (en) 2017-08-21 2019-04-02 Chalbourne Brasington Two-step auto-injection device
CA3101995C (en) 2018-06-08 2023-10-10 Antares Pharma, Inc. Auto-insert injector
EP3659594B1 (de) 2018-11-30 2020-11-18 Klaus Stegemann Eine sterile lösung mit einem medizinischen wirkstoff enthaltende applikationsspritze und verfahren für deren bereitstellung
WO2021030210A1 (en) 2019-08-09 2021-02-18 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291695A (en) * 1976-04-05 1981-09-29 Duphar International Research B.V. Disposable injection syringe
NL178057C (nl) * 1976-04-05 1986-01-16 Duphar Int Res Injectiespuit voor eenmalig gebruik.
NL180634C (nl) * 1977-12-23 1987-04-01 Duphar Int Res Injectiespuit alsmede naaldhouder hiervoor.
DE3103897A1 (de) * 1981-02-05 1982-09-09 Kurt Dr. Schreiner "glasampulle"
US4381779A (en) * 1981-07-16 1983-05-03 Sterling Drug Inc. Deformable slidable piston to provide self-aspiration in hypodermic cartridge ampoules
DE3266681D1 (en) * 1981-07-27 1985-11-07 Duphar Int Res Automatic injection syringe
DE3278101D1 (en) * 1981-08-10 1988-03-17 Duphar Int Res Automatic injection syringe
ATE23802T1 (de) * 1982-10-27 1986-12-15 Duphar Int Res Automatische injektionsvorrichtung.
DE3673317D1 (de) * 1985-10-11 1990-09-13 Duphar Int Res Automatische spritze.
US5002935A (en) * 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
US4893636A (en) * 1988-03-09 1990-01-16 Sherwood Medical Company Medical container stopper

Also Published As

Publication number Publication date
CA2012919A1 (en) 1990-09-28
DE69000716D1 (de) 1993-02-18
IL93881A0 (en) 1990-12-23
ATE84205T1 (de) 1993-01-15
DK0390244T3 (da) 1993-02-08
JPH02283377A (ja) 1990-11-20
EP0390244A1 (de) 1990-10-03
ES2036885T3 (es) 1993-06-01
IL93881A (en) 1994-10-07
EP0390244B1 (de) 1993-01-07
US5383864A (en) 1995-01-24

Similar Documents

Publication Publication Date Title
ATE84205T1 (de) Vorgefuellte injektionsvorrichtung mit einem fass, das mit einer fluessigen diazepam-formulierung gefuellt ist.
ATE394211T1 (de) Vorgefüllte kunststoffspritzen
ATE222127T1 (de) Vorgefüllte spritze zum einspritzen von zwei flüssigkeiten
AU547955B2 (en) Disposable hypodermic syringe
KR840005668A (ko) 주 사 기
ATE96042T1 (de) Injektionsspritze.
GB2297693A (en) Syringes
DE59407728D1 (de) Injektionsspritze zum Mischen und Applizieren von Injektionssubstanzen
ES2047135T3 (es) Jeringuilla de un solo uso que tiene caracteristicas de resistencia a abusos.
GEP20001900B (en) Injection Device with Dual-Chamber Cartridge and Method for Its Preparing
FI881719A0 (fi) Automaattinen kaksikammioinjektioruisku
DK0612255T3 (da) Injektionsindretning
ES2030852T3 (es) Componente conectador de espiga ventilada.
IT8952601V0 (it) Siringa per il lavaggio dei canali radicolari dei denti
SE8306876L (sv) Injektionsspruta
ES2016216A6 (es) Jeringa de un solo uso para inyeccion.
BR9302000A (pt) Seringa com dispositivo de bloqueio da agulha e meio para sua retração na seringa no fim de uma injeção

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee