SE9504661D0 - New compounds - Google Patents
New compoundsInfo
- Publication number
- SE9504661D0 SE9504661D0 SE9504661A SE9504661A SE9504661D0 SE 9504661 D0 SE9504661 D0 SE 9504661D0 SE 9504661 A SE9504661 A SE 9504661A SE 9504661 A SE9504661 A SE 9504661A SE 9504661 D0 SE9504661 D0 SE 9504661D0
- Authority
- SE
- Sweden
- Prior art keywords
- new compounds
- formula
- compounds
- novel compounds
- pain
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (34)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9504661A SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | New compounds |
UA98074034A UA71538C2 (en) | 1995-12-22 | 1996-11-12 | Piperazine or piperidine derivatives, a method for the preparation thereof (variants), a pharmaceutical composition and a method for treatment of diseases (variants) |
ZA9610352A ZA9610352B (en) | 1995-12-22 | 1996-12-09 | Novel compounds with analgesic effect |
EP20030028149 EP1408037A1 (en) | 1995-12-22 | 1996-12-11 | Novel diarylmethylpiperazine and diarylmethylphenyl compounds with analgesic effect |
TR1998/01180T TR199801180T2 (xx) | 1995-12-22 | 1996-12-11 | Aneljestik etkiye sahip yeni bile�ikler. |
CA002239174A CA2239174C (en) | 1995-12-22 | 1996-12-11 | Novel compounds with analgesic effect |
HU9901304A HUP9901304A3 (en) | 1995-12-22 | 1996-12-11 | Piperazine and piperidine derivatives with analgesic effect, process for their preparation and pharmaceutical compositions containing them |
EP96943426A EP0915855A1 (en) | 1995-12-22 | 1996-12-11 | Novel compounds with analgesic effect |
JP09523557A JP2000502679A (ja) | 1995-12-22 | 1996-12-11 | 鎮痛作用を有する新規化合物 |
PL327403A PL193061B1 (pl) | 1995-12-22 | 1996-12-11 | Związki piperazynowe, ich zastosowanie, środek farmaceutyczny i sposób wytwarzania związków piperazynowych |
RU98113786/04A RU2194702C2 (ru) | 1995-12-22 | 1996-12-11 | Производные пиперазина или пиперидина и фармацевтическая композиция |
IL124996A IL124996A (en) | 1995-12-22 | 1996-12-11 | New piparzine compounds, a process for their preparation and use in the preparation of painkillers |
EE9800194A EE04640B1 (et) | 1995-12-22 | 1996-12-11 | Valuvaigistava toimega ühendid |
CZ0176898A CZ296159B6 (cs) | 1995-12-22 | 1996-12-11 | Piperazinové deriváty, zpusob jejich prípravy, jejich pouzití a farmaceutický prostredek s jejich obsahem |
KR10-1998-0704757A KR100493832B1 (ko) | 1995-12-22 | 1996-12-11 | 진통효과가있는신규화합물 |
CN96180102A CN1119336C (zh) | 1995-12-22 | 1996-12-11 | 新的具有止痛作用的化合物 |
BR9612204A BR9612204A (pt) | 1995-12-22 | 1996-12-11 | Composto uso do composto composição farmacêutica e processo para preparação do composto e para o tratamento de dor |
AU12162/97A AU715547B2 (en) | 1995-12-22 | 1996-12-11 | Novel compounds with analgesic effect |
US08/836,830 US6130222A (en) | 1995-12-22 | 1996-12-11 | Compounds with analgesic effect |
NZ324887A NZ324887A (en) | 1995-12-22 | 1996-12-11 | Piperazine and piperidine compounds with analgesic effect |
SK822-98A SK282743B6 (sk) | 1995-12-22 | 1996-12-11 | Piperazínové zlúčeniny, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a ich použitie |
PCT/SE1996/001635 WO1997023466A1 (en) | 1995-12-22 | 1996-12-11 | Novel compounds with analgesic effect |
KR1020057003491A KR20050047534A (ko) | 1995-12-22 | 1996-12-11 | 진통 효과가 있는 신규 화합물을 함유하는 제약 조성물 |
RU2002106503/04A RU2307833C2 (ru) | 1995-12-22 | 1996-12-11 | Способ восстановления нарушенных функций опиоидных рецепторов |
TW085115800A TW458971B (en) | 1995-12-22 | 1996-12-20 | Novel compounds with analgesic effect |
ARP960105834A AR005420A1 (es) | 1995-12-22 | 1996-12-20 | Compuestos derivados de piperazinas y piperidinas con efecto analgésico, composiciones farmacéuticas que los contienen, uso de los mismos para la fabricación de un medicamento y un proceso para la preparación de dichos compuestos. |
MYPI96005403A MY115662A (en) | 1995-12-22 | 1996-12-20 | Novel compounds with analgesic effect |
EG19961162A EG25688A (en) | 1995-12-22 | 1996-12-21 | Novel compounds with analgesic effect |
IS4769A IS1839B (is) | 1995-12-22 | 1998-06-11 | Píperasín afleiður sem hafa verkjastillandi áhrif, framleiðsla og notkun þeirra |
MXPA/A/1998/004798A MXPA98004798A (en) | 1995-12-22 | 1998-06-15 | New compounds with analges effect |
NO19982807A NO310869B1 (no) | 1995-12-22 | 1998-06-18 | Nye forbindelser med analgetisk virkning, farmasöytisk preparat inneholdende slike forbindelser, og anvendelse derav |
US09/631,116 US6680321B1 (en) | 1995-12-22 | 2000-08-02 | Compounds with analgesic effect |
ARP010100517A AR034116A2 (es) | 1995-12-22 | 2001-02-05 | Derivados de piperazinas y piperidinas con efecto analgesico, composiciones farmaceuticas que los contienen, uso de los mismos para la fabricacion de un medicamento y un proceso para la preparacion de dichos compuestos |
US10/714,447 US20040138228A1 (en) | 1995-12-22 | 2003-11-17 | Novel compounds with analgesic effect |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9504661A SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | New compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9504661D0 true SE9504661D0 (sv) | 1995-12-22 |
Family
ID=20400739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9504661A SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | New compounds |
Country Status (27)
Country | Link |
---|---|
US (3) | US6130222A (xx) |
EP (2) | EP0915855A1 (xx) |
JP (1) | JP2000502679A (xx) |
KR (2) | KR20050047534A (xx) |
CN (1) | CN1119336C (xx) |
AR (2) | AR005420A1 (xx) |
AU (1) | AU715547B2 (xx) |
BR (1) | BR9612204A (xx) |
CA (1) | CA2239174C (xx) |
CZ (1) | CZ296159B6 (xx) |
EE (1) | EE04640B1 (xx) |
EG (1) | EG25688A (xx) |
HU (1) | HUP9901304A3 (xx) |
IL (1) | IL124996A (xx) |
IS (1) | IS1839B (xx) |
MY (1) | MY115662A (xx) |
NO (1) | NO310869B1 (xx) |
NZ (1) | NZ324887A (xx) |
PL (1) | PL193061B1 (xx) |
RU (2) | RU2194702C2 (xx) |
SE (1) | SE9504661D0 (xx) |
SK (1) | SK282743B6 (xx) |
TR (1) | TR199801180T2 (xx) |
TW (1) | TW458971B (xx) |
UA (1) | UA71538C2 (xx) |
WO (1) | WO1997023466A1 (xx) |
ZA (1) | ZA9610352B (xx) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6410537B1 (en) * | 1994-09-09 | 2002-06-25 | The United States Of America As Represented By The Secretary Of The Army | Compositions having neuroprotective and analgesic activity |
SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
TW548271B (en) | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
GB9709972D0 (en) * | 1997-05-19 | 1997-07-09 | Pfizer Ltd | Tetrazoles |
WO1999033806A1 (en) * | 1997-12-24 | 1999-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor |
GB9804734D0 (en) * | 1998-03-05 | 1998-04-29 | Pfizer Ltd | Compounds |
US6011035A (en) * | 1998-06-30 | 2000-01-04 | Neuromed Technologies Inc. | Calcium channel blockers |
GB9819382D0 (en) * | 1998-09-04 | 1998-10-28 | Cerebrus Ltd | Chemical compounds I |
US6436959B1 (en) | 1998-12-23 | 2002-08-20 | Ortho-Mcneil Pharmaceutical, Inc. | 4-[aryl(piperidin-4-yl)]aminobenzamides |
SE9904673D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
SE9904674D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
US6306876B1 (en) | 1999-12-22 | 2001-10-23 | Ortho-Mcneil Pharmaceutical, Inc. | 4-[aryl(8-azabicyclo[3.2.1]octan-3-yl)]aminobenzoic acid derivatives |
JP2003525938A (ja) | 2000-03-03 | 2003-09-02 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 3−(ジアリールメチレン)−8−アザビシクロ[3.2.1]オクタン誘導体 |
SE0001209D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
SE0001208D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
JP2004517081A (ja) * | 2000-11-29 | 2004-06-10 | イーライ・リリー・アンド・カンパニー | 1−(2−m−メタンスルホンアミドフェニルエチル)−4−(m−トリフルオロメチルフェニル)ピペラジンならびにその医薬的に許容しうる塩および溶媒和物 |
WO2002048122A2 (en) * | 2000-12-14 | 2002-06-20 | Ortho-Mcneil Pharmaceutical, Inc. | Benzamidine derivatives |
SE0100764D0 (sv) | 2001-03-07 | 2001-03-07 | Astrazeneca Ab | New assymetric process |
MXPA03010445A (es) | 2001-05-18 | 2004-03-09 | Astrazeneca Ab | Derivados de 4(fenil-piperazinil-metil) benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales. |
SE0101768D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
SE0101765D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
SE0101766D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
GB0119797D0 (en) | 2001-08-14 | 2001-10-03 | Glaxo Group Ltd | Chemical compounds |
SE0103313D0 (sv) | 2001-10-03 | 2001-10-03 | Astrazeneca Ab | Novel compounds |
RU2314809C2 (ru) | 2001-10-29 | 2008-01-20 | Маунт Кук Байосайенсиз, Инк. | Способ лечения депрессии соединениями-агонистами дельта-рецепторов |
AU2003214800A1 (en) | 2002-01-02 | 2003-07-24 | Ardent Pharmaceuticals, Inc. | Method of treating sexual dysfunctions with delta opioid receptor agonist compounds |
US8476280B2 (en) * | 2002-05-09 | 2013-07-02 | Versi Group, Llc | Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists |
US20040082612A1 (en) * | 2002-10-15 | 2004-04-29 | Baxter Ellen W | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives |
SE0203303D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203300D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203302D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
SE0400027D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
EP1737853A1 (en) | 2004-02-03 | 2007-01-03 | Janssen Pharmaceutica N.V. | 3-(diheteroarylmethylene)-8-azabicyclo¬3.2.1|octane and 3-((aryl)(heteroaryl)methylene)-8-azabicyclo¬3.2.1|octane derivatives |
DK1781631T3 (da) | 2004-08-02 | 2012-05-14 | Astrazeneca Ab | Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf |
SE0401968D0 (sv) * | 2004-08-02 | 2004-08-02 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
SE0402485D0 (sv) | 2004-10-13 | 2004-10-13 | Astrazeneca Ab | Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt |
US7598261B2 (en) * | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
CA2643677C (en) * | 2005-04-14 | 2015-06-23 | Mount Cook Biosciences, Inc. | Compositions of novel opioid compounds and method of use thereof |
KR20080016933A (ko) * | 2005-06-20 | 2008-02-22 | 아스트라제네카 아베 | (알콕시카보닐아미노)알킬 설포네이트의 제조 방법 |
JP2011520956A (ja) * | 2008-05-20 | 2011-07-21 | アストラゼネカ・アクチエボラーグ | 不安大うつ病性障害を処置する方法 |
NZ590616A (en) | 2008-06-20 | 2012-09-28 | Astrazeneca Ab | Dibenzothiazepine derivatives and use thereof |
US20110172425A1 (en) | 2008-09-17 | 2011-07-14 | Calyx Chemicals And Pharmaceuticals Pvt. Ltd. | Novel water based process for the preparation of substituted diphenylmethyl piperazines |
US20100311782A1 (en) * | 2009-06-08 | 2010-12-09 | Adolor Corporation | Substituted piperidinylpropanoic acid compounds and methods of their use |
GB201111705D0 (en) | 2011-07-07 | 2011-08-24 | Takeda Pharmaceutical | Compounds and their use |
GB201111704D0 (en) | 2011-07-07 | 2011-08-24 | Takeda Pharmaceutical | Novel compounds |
JO3115B1 (ar) | 2011-08-22 | 2017-09-20 | Takeda Pharmaceuticals Co | مركبات بيريدازينون واستخدامها كمثبطات daao |
GB201209587D0 (en) | 2012-05-30 | 2012-07-11 | Takeda Pharmaceutical | Therapeutic compounds |
US10208016B2 (en) | 2013-06-21 | 2019-02-19 | Takeda Pharmaceutical Company Limited | 1-sulfonyl piperidine derivatives as modulators of prokineticin receptors |
GB201314286D0 (en) | 2013-08-08 | 2013-09-25 | Takeda Pharmaceutical | Therapeutic Compounds |
GB201318222D0 (en) | 2013-10-15 | 2013-11-27 | Takeda Pharmaceutical | Novel compounds |
GB201320905D0 (en) | 2013-11-27 | 2014-01-08 | Takeda Pharmaceutical | Therapeutic compounds |
TW201613864A (en) | 2014-02-20 | 2016-04-16 | Takeda Pharmaceutical | Novel compounds |
GB201616839D0 (en) | 2016-10-04 | 2016-11-16 | Takeda Pharmaceutical Company Limited | Therapeutic compounds |
GB201619514D0 (en) | 2016-11-18 | 2017-01-04 | Takeda Pharmaceuticals Co | Novel compounds |
JP2021138648A (ja) | 2020-03-04 | 2021-09-16 | 武田薬品工業株式会社 | 経口固形製剤 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH585209A5 (xx) * | 1973-06-29 | 1977-02-28 | Cermol Sa | |
DE2900810A1 (de) * | 1979-01-11 | 1980-07-24 | Cassella Ag | Substituierte n-benzhydryl-n'-p- hydroxybenzyl-piperazine und verfahren zu ihrer herstellung |
IT1140978B (it) * | 1980-05-23 | 1986-10-10 | Selvi & C Spa | 1-(4-clorobenzidril)-4-(2,3-diidros sipropil)-piperazina, metodi per la sua preparazione e relative composizione farmaceutiche |
GB8320701D0 (en) * | 1983-08-01 | 1983-09-01 | Wellcome Found | Chemotherapeutic agent |
IT1196150B (it) * | 1984-06-19 | 1988-11-10 | Poli Ind Chimica Spa | Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono |
SE8500573D0 (sv) | 1985-02-08 | 1985-02-08 | Ferrosan Ab | Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain |
US5028610A (en) * | 1987-03-18 | 1991-07-02 | Sankyo Company Limited | N-benzhydryl-substituted heterocyclic derivatives, their preparation and their use |
US4829065A (en) * | 1987-04-24 | 1989-05-09 | Syntex Pharmaceuticals, Ltd. | Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives |
US4826844A (en) * | 1987-09-30 | 1989-05-02 | American Home Products Corporation | Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols |
EP0455789B1 (en) | 1989-11-22 | 1994-03-16 | Janssen Pharmaceutica N.V. | Method of preventing or limiting reperfusion damage |
GB9202238D0 (en) * | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
US5574159A (en) | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
US5807858A (en) * | 1996-06-05 | 1998-09-15 | Delta Pharmaceutical, Inc. | Compositions and methods for reducing respiratory depression |
US5681830A (en) * | 1992-02-03 | 1997-10-28 | Delta Pharmaceuticals, Inc. | Opioid compounds |
FR2696744B1 (fr) * | 1992-10-12 | 1994-12-30 | Logeais Labor Jacques | Dérivés de 2-pyrrolidone, leur procédé de préparation et leurs applications en thérapeutique. |
ATE195733T1 (de) * | 1993-07-30 | 2000-09-15 | Delta Pharmaceuticals Inc | Als heilmittel nutzbare piperazin verbindungen |
JP3352184B2 (ja) * | 1993-11-12 | 2002-12-03 | 株式会社アズウェル | ピペラジン不飽和脂肪酸誘導体 |
SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
SE9504662D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
TW548271B (en) | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
SE9604786D0 (sv) | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
WO1999033806A1 (en) | 1997-12-24 | 1999-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor |
SE0001209D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
1995
- 1995-12-22 SE SE9504661A patent/SE9504661D0/xx unknown
-
1996
- 1996-11-12 UA UA98074034A patent/UA71538C2/uk unknown
- 1996-12-09 ZA ZA9610352A patent/ZA9610352B/xx unknown
- 1996-12-11 BR BR9612204A patent/BR9612204A/pt active IP Right Grant
- 1996-12-11 EE EE9800194A patent/EE04640B1/xx not_active IP Right Cessation
- 1996-12-11 JP JP09523557A patent/JP2000502679A/ja active Pending
- 1996-12-11 HU HU9901304A patent/HUP9901304A3/hu unknown
- 1996-12-11 PL PL327403A patent/PL193061B1/pl not_active IP Right Cessation
- 1996-12-11 TR TR1998/01180T patent/TR199801180T2/xx unknown
- 1996-12-11 CA CA002239174A patent/CA2239174C/en not_active Expired - Fee Related
- 1996-12-11 IL IL124996A patent/IL124996A/en not_active IP Right Cessation
- 1996-12-11 CZ CZ0176898A patent/CZ296159B6/cs not_active IP Right Cessation
- 1996-12-11 EP EP96943426A patent/EP0915855A1/en not_active Withdrawn
- 1996-12-11 KR KR1020057003491A patent/KR20050047534A/ko not_active Application Discontinuation
- 1996-12-11 CN CN96180102A patent/CN1119336C/zh not_active Expired - Fee Related
- 1996-12-11 EP EP20030028149 patent/EP1408037A1/en not_active Ceased
- 1996-12-11 AU AU12162/97A patent/AU715547B2/en not_active Ceased
- 1996-12-11 WO PCT/SE1996/001635 patent/WO1997023466A1/en active IP Right Grant
- 1996-12-11 SK SK822-98A patent/SK282743B6/sk not_active IP Right Cessation
- 1996-12-11 NZ NZ324887A patent/NZ324887A/xx not_active IP Right Cessation
- 1996-12-11 RU RU98113786/04A patent/RU2194702C2/ru not_active IP Right Cessation
- 1996-12-11 KR KR10-1998-0704757A patent/KR100493832B1/ko not_active IP Right Cessation
- 1996-12-11 RU RU2002106503/04A patent/RU2307833C2/ru not_active IP Right Cessation
- 1996-12-11 US US08/836,830 patent/US6130222A/en not_active Expired - Fee Related
- 1996-12-20 AR ARP960105834A patent/AR005420A1/es not_active Application Discontinuation
- 1996-12-20 MY MYPI96005403A patent/MY115662A/en unknown
- 1996-12-20 TW TW085115800A patent/TW458971B/zh not_active IP Right Cessation
- 1996-12-21 EG EG19961162A patent/EG25688A/xx active
-
1998
- 1998-06-11 IS IS4769A patent/IS1839B/is unknown
- 1998-06-18 NO NO19982807A patent/NO310869B1/no not_active IP Right Cessation
-
2000
- 2000-08-02 US US09/631,116 patent/US6680321B1/en not_active Expired - Fee Related
-
2001
- 2001-02-05 AR ARP010100517A patent/AR034116A2/es active IP Right Grant
-
2003
- 2003-11-17 US US10/714,447 patent/US20040138228A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE9504661D0 (sv) | New compounds | |
MY119403A (en) | Novel compounds with analgesic effect. | |
SE9604786D0 (sv) | New compounds | |
SE9900961D0 (sv) | Novel compounds | |
TR200200579T2 (tr) | Amino-tirazolpiridin türevleri. | |
SE0101387D0 (sv) | Novel compounds | |
BR9611175B1 (pt) | compostos e composiÇÕes farmacÊuticas. | |
MX9707453A (es) | Derivados de quinazolina. | |
MX9700885A (es) | Nuevas heteroariloxazolidinonas. | |
SE9802208D0 (sv) | Novel compounds | |
DK0944643T3 (da) | Oxyiminopregnancarbolactoner. | |
IT1285770B1 (it) | Composti corticoidei | |
SE9802206D0 (sv) | Novel compounds | |
SE0104250D0 (sv) | Heterocyclic compounds | |
SE0300908D0 (sv) | Azaindole derivatives, preparations thereof, uses thereof and compositions containing them | |
SE0203070D0 (en) | Novel compounds | |
SE9504662D0 (sv) | New compounds | |
KR960703863A (ko) | 암 치료용 신규 비스-나프탈이미드(New Bis-naphthalimides for the Treatment of Cancer) | |
SE9802209D0 (sv) | Novel compounds | |
TR200001909T2 (tr) | Matris metaloprotez inhibitörleri. | |
ES2192789T3 (es) | Derivados de hidrazono-benzazuleno, composiciones farmaceuticas y compuestos intermedios. | |
MY133169A (en) | Substituted heterocyclic benzocycloalkenes and the use thereof as substances having an analgesic effect | |
ATE286395T1 (de) | Antithrombotische mittel | |
TR199900013T2 (xx) | Yeni bile�ikler. | |
SE9802538D0 (sv) | New pharmaceutically active compounds |