SE9301581D0 - Protein formulation - Google Patents

Protein formulation

Info

Publication number
SE9301581D0
SE9301581D0 SE19939301581A SE9301581A SE9301581D0 SE 9301581 D0 SE9301581 D0 SE 9301581D0 SE 19939301581 A SE19939301581 A SE 19939301581A SE 9301581 A SE9301581 A SE 9301581A SE 9301581 D0 SE9301581 D0 SE 9301581D0
Authority
SE
Sweden
Prior art keywords
factor viii
pct
aqueous solution
present
activity
Prior art date
Application number
SE19939301581A
Other languages
English (en)
Swedish (sv)
Inventor
*Oesterberg Thomas
*Fatouros Angelica
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE19939301581A priority Critical patent/SE9301581D0/xx
Publication of SE9301581D0 publication Critical patent/SE9301581D0/xx
Priority to CZ19952869A priority patent/CZ293527B6/cs
Priority to DE69430745T priority patent/DE69430745T2/de
Priority to JP52470394A priority patent/JP3751633B2/ja
Priority to HU9503171A priority patent/HU215263B/hu
Priority to US08/535,251 priority patent/US5962650A/en
Priority to EP94915307A priority patent/EP0700299B1/en
Priority to SK1383-95A priority patent/SK283002B6/sk
Priority to CN94192021A priority patent/CN1113655C/zh
Priority to RU95121755A priority patent/RU2142290C1/ru
Priority to PT94915307T priority patent/PT700299E/pt
Priority to PCT/SE1994/000265 priority patent/WO1994026286A1/en
Priority to NZ266031A priority patent/NZ266031A/en
Priority to ES94915307T priority patent/ES2177579T3/es
Priority to AT94915307T priority patent/ATE218354T1/de
Priority to CA002161350A priority patent/CA2161350C/en
Priority to DK94915307T priority patent/DK0700299T3/da
Priority to AU66597/94A priority patent/AU681883B2/en
Priority to KR1019950704933A priority patent/KR100304143B1/ko
Priority to PL94311567A priority patent/PL174866B1/pl
Priority to ZA942251A priority patent/ZA942251B/xx
Priority to EE9400380A priority patent/EE03118B1/xx
Priority to FI955305A priority patent/FI111910B/fi
Priority to NO19954457A priority patent/NO321769B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
SE19939301581A 1993-05-07 1993-05-07 Protein formulation SE9301581D0 (sv)

Priority Applications (24)

Application Number Priority Date Filing Date Title
SE19939301581A SE9301581D0 (sv) 1993-05-07 1993-05-07 Protein formulation
PL94311567A PL174866B1 (pl) 1993-05-07 1994-03-24 Sposób wytwarzania leku zawierającego czynnik krzepnięcia VIII
PT94915307T PT700299E (pt) 1993-05-07 1994-03-24 Solucao aquosa de factor viii com teor de oxigenio reduzido
NZ266031A NZ266031A (en) 1993-05-07 1994-03-24 Factor viii composition with reduced dissolved oxygen
JP52470394A JP3751633B2 (ja) 1993-05-07 1994-03-24 因子ｖｉｉｉの酸素低減水溶液
HU9503171A HU215263B (hu) 1993-05-07 1994-03-24 VIII faktor csökkentett oxigéntartalmú vizes oldata
US08/535,251 US5962650A (en) 1993-05-07 1994-03-24 Oxygen-reduced aqueous solution of factor VIII
EP94915307A EP0700299B1 (en) 1993-05-07 1994-03-24 Oxygen-reduced aqueous solution of factor viii
SK1383-95A SK283002B6 (sk) 1993-05-07 1994-03-24 Prípravok s obsahom koagulačného faktora VIII
CN94192021A CN1113655C (zh) 1993-05-07 1994-03-24 氧降低的凝固因子vⅲ水溶液
RU95121755A RU2142290C1 (ru) 1993-05-07 1994-03-24 Водный раствор фактора viii со сниженной концентрацией кислорода
CZ19952869A CZ293527B6 (cs) 1993-05-07 1994-03-24 Formulace s obsahem koagulačního faktoru VIII a způsob její přípravy
PCT/SE1994/000265 WO1994026286A1 (en) 1993-05-07 1994-03-24 Oxygen-reduced aqueous solution of factor viii
DE69430745T DE69430745T2 (de) 1993-05-07 1994-03-24 Sauerstoff reduzierte wässerige faktor viii-enthaltene lösung
ES94915307T ES2177579T3 (es) 1993-05-07 1994-03-24 Solucion acuosa de factor viii de bajo contenido en oxigeno.
AT94915307T ATE218354T1 (de) 1993-05-07 1994-03-24 Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung
CA002161350A CA2161350C (en) 1993-05-07 1994-03-24 Oxygen-reduced aqueous solution of factor viii
DK94915307T DK0700299T3 (da) 1993-05-07 1994-03-24 Oxygen-reduceret, vandig faktor VIII-opløsning
AU66597/94A AU681883B2 (en) 1993-05-07 1994-03-24 Oxygen-reduced aqueous solution of factor VIII
KR1019950704933A KR100304143B1 (ko) 1993-05-07 1994-03-24 산소가감소된인자viii의수용액
ZA942251A ZA942251B (en) 1993-05-07 1994-04-02 Protein formulation.
EE9400380A EE03118B1 (et) 1993-05-07 1994-11-17 Proteiinravim ja selle valmistamismeetod
FI955305A FI111910B (fi) 1993-05-07 1995-11-06 Menetelmä hyytymistekijää VIII sisältävän lääkeainevalmisteen valmistamiseksi
NO19954457A NO321769B1 (no) 1993-05-07 1995-11-07 Oksygenredusert vandig opplosning av faktor VIII og fremgangsmate for fremstilling av denne.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE19939301581A SE9301581D0 (sv) 1993-05-07 1993-05-07 Protein formulation

Publications (1)

Publication Number Publication Date
SE9301581D0 true SE9301581D0 (sv) 1993-05-07

Family

ID=20389868

Family Applications (1)

Application Number Title Priority Date Filing Date
SE19939301581A SE9301581D0 (sv) 1993-05-07 1993-05-07 Protein formulation

Country Status (24)

Country Link
US (1) US5962650A (cs)
EP (1) EP0700299B1 (cs)
JP (1) JP3751633B2 (cs)
KR (1) KR100304143B1 (cs)
CN (1) CN1113655C (cs)
AT (1) ATE218354T1 (cs)
AU (1) AU681883B2 (cs)
CA (1) CA2161350C (cs)
CZ (1) CZ293527B6 (cs)
DE (1) DE69430745T2 (cs)
DK (1) DK0700299T3 (cs)
EE (1) EE03118B1 (cs)
ES (1) ES2177579T3 (cs)
FI (1) FI111910B (cs)
HU (1) HU215263B (cs)
NO (1) NO321769B1 (cs)
NZ (1) NZ266031A (cs)
PL (1) PL174866B1 (cs)
PT (1) PT700299E (cs)
RU (1) RU2142290C1 (cs)
SE (1) SE9301581D0 (cs)
SK (1) SK283002B6 (cs)
WO (1) WO1994026286A1 (cs)
ZA (1) ZA942251B (cs)

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IL113010A (en) * 1994-03-31 1999-10-28 Pharmacia & Upjohn Ab Pharmaceutical formulation comprising factor viii with an activity of at least 500iu/ml and an enhancer for improved subcutaneous intramuscular or intradermal administration
SE9403915D0 (sv) * 1994-11-14 1994-11-14 Annelie Almstedt Process A
SE9501189D0 (sv) * 1995-03-31 1995-03-31 Pharmacia Ab Protein formulation
US5929031A (en) * 1995-05-02 1999-07-27 Baxter Biotech Technology Sarl Storage stable hemoglobin solutions
US5925738A (en) * 1995-12-01 1999-07-20 The American National Red Cross Methods of production and use of liquid formulations of plasma proteins
US7560107B2 (en) * 1996-06-26 2009-07-14 Emory University Modified factor VIII
US5763401A (en) * 1996-07-12 1998-06-09 Bayer Corporation Stabilized albumin-free recombinant factor VIII preparation having a low sugar content
WO2000048635A1 (en) 1999-02-22 2000-08-24 Baxter International Inc. Novel albumin-free factor viii formulations
NZ516400A (en) * 1999-07-13 2004-02-27 Biovitrum Ab Stable factor VIII compositions
JP3466516B2 (ja) * 1999-09-07 2003-11-10 科学技術振興事業団 安定保存可能な酸素輸液剤
AU2002351755A1 (en) * 2001-12-21 2003-07-15 Novo Nordisk A/S Liquid composition of modified factor vii polypeptides
ES2325653T3 (es) * 2001-12-21 2009-09-11 Novo Nordisk Health Care Ag Composicion liquida de polipeptidos del factor vii.
GB0207092D0 (en) 2002-03-26 2002-05-08 Sod Conseils Rech Applic Stable pharmaceutical composition containing factor VIII
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
WO2004000347A1 (en) * 2002-06-21 2003-12-31 Novo Nordisk A/S Stabilised solid compositions of factor vii polypeptides
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
CA2525224A1 (en) 2003-05-23 2004-12-02 Michael Bech Jensen Protein stabilization in solution
JP4658041B2 (ja) 2003-06-25 2011-03-23 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト Ｖｉｉ因子ポリペプチドの液体組成物
EP1644030B1 (en) * 2003-07-01 2009-10-28 Novo Nordisk Health Care AG Liquid, aqueous pharmaceutical composition of factor vii polypeptides
CA2534028A1 (en) 2003-08-14 2005-02-24 Novo Nordisk Health Care Ag Liquid, aqueous pharmaceutical composition of factor vii polypeptides
EP2298287B1 (en) 2003-12-19 2018-04-11 Novo Nordisk Health Care AG Stabilised compositions of factor VII polypeptides
ES2449044T3 (es) * 2004-05-03 2014-03-18 Emory University Procedimiento de administración de fVIII sin dominio B porcino
US7494974B2 (en) 2006-10-24 2009-02-24 Ikor, Inc. Carboxymethylated cross-linked tetrameric hemoglobin
US7504377B2 (en) 2006-10-23 2009-03-17 Ikor, Inc. Nitric oxide-blocked cross-linked tetrameric hemoglobin
DE502007004128D1 (de) * 2007-04-17 2010-07-29 Schwabe Willmar Gmbh & Co Verfahren zur Herstellung von lagerstabilen Lösungen aus Pelargonium-Extrakten
CA2692814A1 (en) * 2007-07-11 2009-01-15 Novo Nordisk A/S Purification of factor viii using a mixed-mode or multimodal resin
EP2113564A1 (en) 2008-05-01 2009-11-04 Arecor Limited Protein formulation
US9120873B2 (en) 2008-08-21 2015-09-01 Octapharma Ag Recombinantly produced human factor VIII and IX
SI2337580T1 (sl) * 2008-09-03 2012-06-29 Octapharma Ag Stabilizirani sestavki za rekombinanto proizveden faktor VIII
ES2706296T3 (es) 2008-11-07 2019-03-28 Univ Connecticut Formulaciones de Factor VIII
KR20180126103A (ko) 2009-06-09 2018-11-26 프로롱 파마슈티컬스, 엘엘씨 헤모글로빈 조성물
US10172949B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
US10172950B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
GB0915480D0 (en) * 2009-09-04 2009-10-07 Arecor Ltd Stable formulation of factor viii
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
JP5930483B2 (ja) 2010-08-25 2016-06-08 ニュー・ヘルス・サイエンシーズ・インコーポレイテッドＮｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． 保存中の赤血球の品質及び生存を高める方法
ES2793484T3 (es) 2010-11-05 2020-11-16 Hemanext Inc Irradiación de glóbulos rojos y almacenamiento anaeróbico
SG10201509149VA (en) 2010-11-05 2015-12-30 Baxter Int A new variant of antihemophilic factor viii having increased specific activity
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
JP6097293B2 (ja) 2011-08-10 2017-03-15 ニュー・ヘルス・サイエンシーズ・インコーポレイテッドＮｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． 一体型の白血球、酸素及び／又は二酸化炭素減損・血漿分離フィルタ装置
US9877476B2 (en) 2013-02-28 2018-01-30 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
ES2524516B1 (es) * 2014-05-29 2015-03-31 Grifols Worldwide Operations Limited Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido
ES2902499T3 (es) 2015-03-10 2022-03-28 Hemanext Inc Kits desechables de reducción de oxígeno, dispositivos y procedimientos de uso de los mismos
KR102661405B1 (ko) 2015-04-23 2024-04-25 헤마넥스트 인코포레이티드 혐기성 혈액 저장 용기
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BR112018073923A2 (pt) 2016-05-27 2019-02-26 New Health Sciences, Inc. armazenamento anaeróbico de sangue e método de inativação de patógenos
BR112021000965A2 (pt) 2018-08-07 2021-04-27 Glaxosmithkline Biologicals S.A. processos e vacinas

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Also Published As

Publication number Publication date
DE69430745T2 (de) 2002-10-17
EP0700299A1 (en) 1996-03-13
HU9503171D0 (en) 1996-01-29
DK0700299T3 (da) 2002-09-23
ZA942251B (en) 1994-11-01
FI955305A0 (fi) 1995-11-06
NO954457D0 (no) 1995-11-07
PT700299E (pt) 2002-11-29
AU681883B2 (en) 1997-09-11
PL311567A1 (en) 1996-02-19
NO954457L (no) 1995-11-07
KR100304143B1 (ko) 2001-11-22
HUT73693A (en) 1996-09-30
ES2177579T3 (es) 2002-12-16
WO1994026286A1 (en) 1994-11-24
RU2142290C1 (ru) 1999-12-10
NZ266031A (en) 1997-04-24
FI111910B (fi) 2003-10-15
ATE218354T1 (de) 2002-06-15
AU6659794A (en) 1994-12-12
CZ293527B6 (cs) 2004-05-12
EP0700299B1 (en) 2002-06-05
CZ286995A3 (en) 1996-05-15
CN1113655C (zh) 2003-07-09
HU215263B (hu) 1998-11-30
CN1122573A (zh) 1996-05-15
NO321769B1 (no) 2006-07-03
US5962650A (en) 1999-10-05
PL174866B1 (pl) 1998-09-30
KR960702317A (ko) 1996-04-27
FI955305L (fi) 1995-11-06
CA2161350A1 (en) 1994-11-24
DE69430745D1 (de) 2002-07-11
SK138395A3 (en) 1997-02-05
EE03118B1 (et) 1998-10-15
SK283002B6 (sk) 2003-01-09
JP3751633B2 (ja) 2006-03-01
JPH08509745A (ja) 1996-10-15
CA2161350C (en) 2007-10-30

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