ATE218354T1 - Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung - Google Patents

Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung

Info

Publication number
ATE218354T1
ATE218354T1 AT94915307T AT94915307T ATE218354T1 AT E218354 T1 ATE218354 T1 AT E218354T1 AT 94915307 T AT94915307 T AT 94915307T AT 94915307 T AT94915307 T AT 94915307T AT E218354 T1 ATE218354 T1 AT E218354T1
Authority
AT
Austria
Prior art keywords
factor viii
pct
aqueous solution
present
solution containing
Prior art date
Application number
AT94915307T
Other languages
English (en)
Inventor
Thomas Oesterberg
Angelica Fatouros
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Application granted granted Critical
Publication of ATE218354T1 publication Critical patent/ATE218354T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94915307T 1993-05-07 1994-03-24 Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung ATE218354T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19939301581A SE9301581D0 (sv) 1993-05-07 1993-05-07 Protein formulation
PCT/SE1994/000265 WO1994026286A1 (en) 1993-05-07 1994-03-24 Oxygen-reduced aqueous solution of factor viii

Publications (1)

Publication Number Publication Date
ATE218354T1 true ATE218354T1 (de) 2002-06-15

Family

ID=20389868

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94915307T ATE218354T1 (de) 1993-05-07 1994-03-24 Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung

Country Status (24)

Country Link
US (1) US5962650A (de)
EP (1) EP0700299B1 (de)
JP (1) JP3751633B2 (de)
KR (1) KR100304143B1 (de)
CN (1) CN1113655C (de)
AT (1) ATE218354T1 (de)
AU (1) AU681883B2 (de)
CA (1) CA2161350C (de)
CZ (1) CZ293527B6 (de)
DE (1) DE69430745T2 (de)
DK (1) DK0700299T3 (de)
EE (1) EE03118B1 (de)
ES (1) ES2177579T3 (de)
FI (1) FI111910B (de)
HU (1) HU215263B (de)
NO (1) NO321769B1 (de)
NZ (1) NZ266031A (de)
PL (1) PL174866B1 (de)
PT (1) PT700299E (de)
RU (1) RU2142290C1 (de)
SE (1) SE9301581D0 (de)
SK (1) SK283002B6 (de)
WO (1) WO1994026286A1 (de)
ZA (1) ZA942251B (de)

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US5763401A (en) * 1996-07-12 1998-06-09 Bayer Corporation Stabilized albumin-free recombinant factor VIII preparation having a low sugar content
ES2435141T3 (es) 1999-02-22 2013-12-18 University Of Connecticut Nuevas formulaciones de factor VIII libres de albúmina
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JP3466516B2 (ja) 1999-09-07 2003-11-10 科学技術振興事業団 安定保存可能な酸素輸液剤
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GB0207092D0 (en) 2002-03-26 2002-05-08 Sod Conseils Rech Applic Stable pharmaceutical composition containing factor VIII
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
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US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
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WO2004112828A1 (en) 2003-06-25 2004-12-29 Novo Nordisk Health Care Ag Liquid composition of factor vii polypeptides
JP5306597B2 (ja) * 2003-07-01 2013-10-02 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 第ｖｉｉ因子ポリペプチドの液体水性薬学的組成物
RU2388460C2 (ru) 2003-08-14 2010-05-10 Ново Нордиск Хелс Кеа Аг Жидкая водная фармацевтическая композиция, содержащая полипептид фактора vii
KR20140093711A (ko) * 2003-12-19 2014-07-28 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ｖｉｉ 폴리펩티드의 안정화된 조성물
PT1750733E (pt) * 2004-05-03 2014-02-14 Baxter Healthcare Sa Método de administração de factor viii suíno sem domínio b
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US7504377B2 (en) 2006-10-23 2009-03-17 Ikor, Inc. Nitric oxide-blocked cross-linked tetrameric hemoglobin
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CA2692814A1 (en) * 2007-07-11 2009-01-15 Novo Nordisk A/S Purification of factor viii using a mixed-mode or multimodal resin
EP2113564A1 (de) 2008-05-01 2009-11-04 Arecor Limited Proteinformulierung
KR101921698B1 (ko) 2008-08-21 2018-11-26 옥타파마 아게 재조합에 의해 제조된 인간 인자 ⅷ 및 ⅸ
PT2337580E (pt) * 2008-09-03 2012-05-28 Octapharma Ag Composições estabilizadas para o factor viii produzido de forma recombinante
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
US10172950B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
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DK2440239T3 (en) 2009-06-09 2017-10-16 Prolong Pharmaceuticals Llc HEMOGLOBIN FORMATIONS
GB0915480D0 (en) * 2009-09-04 2009-10-07 Arecor Ltd Stable formulation of factor viii
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US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
EP4091645A1 (de) 2010-08-25 2022-11-23 Hemanext Inc. Verfahren zur erhöhung der qualität von erythrozyten und zur verlängerung ihrer lebensdauer während der lagerung
PT3539381T (pt) 2010-11-05 2023-09-26 Hemanext Inc Irradiação de glóbulos vermelhos e armazenamento anaeróbico
CN103298483B (zh) 2010-11-05 2017-04-12 百深有限责任公司 具有增加的比活性的抗血友病因子viii的新型变体
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
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ES2524516B1 (es) * 2014-05-29 2015-03-31 Grifols Worldwide Operations Limited Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido
CA3211996A1 (en) 2015-03-10 2016-09-15 Hemanext Inc. Oxygen reduction disposable kits, devices and methods of use thereof
KR20250126858A (ko) 2015-04-23 2025-08-25 헤마넥스트 인코포레이티드 혐기성 혈액 저장 용기
CA2985799A1 (en) 2015-05-18 2016-11-24 New Health Sciences, Inc. Methods for the storage of whole blood, and compositions thereof
US11147876B2 (en) 2016-05-27 2021-10-19 Hemanext Inc. Anaerobic blood storage and pathogen inactivation method
CN112601545A (zh) 2018-08-07 2021-04-02 葛兰素史密丝克莱恩生物有限公司 工艺和疫苗

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Also Published As

Publication number Publication date
DE69430745D1 (de) 2002-07-11
EP0700299B1 (de) 2002-06-05
AU681883B2 (en) 1997-09-11
CN1113655C (zh) 2003-07-09
FI955305L (fi) 1995-11-06
EP0700299A1 (de) 1996-03-13
RU2142290C1 (ru) 1999-12-10
SE9301581D0 (sv) 1993-05-07
ZA942251B (en) 1994-11-01
CN1122573A (zh) 1996-05-15
PT700299E (pt) 2002-11-29
NO954457D0 (no) 1995-11-07
PL174866B1 (pl) 1998-09-30
FI955305A0 (fi) 1995-11-06
JPH08509745A (ja) 1996-10-15
CZ286995A3 (en) 1996-05-15
JP3751633B2 (ja) 2006-03-01
ES2177579T3 (es) 2002-12-16
KR100304143B1 (ko) 2001-11-22
CZ293527B6 (cs) 2004-05-12
KR960702317A (ko) 1996-04-27
HUT73693A (en) 1996-09-30
EE03118B1 (et) 1998-10-15
HU215263B (hu) 1998-11-30
PL311567A1 (en) 1996-02-19
SK138395A3 (en) 1997-02-05
WO1994026286A1 (en) 1994-11-24
NO954457L (no) 1995-11-07
AU6659794A (en) 1994-12-12
CA2161350A1 (en) 1994-11-24
CA2161350C (en) 2007-10-30
NZ266031A (en) 1997-04-24
SK283002B6 (sk) 2003-01-09
DK0700299T3 (da) 2002-09-23
DE69430745T2 (de) 2002-10-17
HU9503171D0 (en) 1996-01-29
FI111910B (fi) 2003-10-15
US5962650A (en) 1999-10-05
NO321769B1 (no) 2006-07-03

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UEP Publication of translation of european patent specification