SE9103572D0 - Organic salts of n,n'-diacetyl cystine - Google Patents

Organic salts of n,n'-diacetyl cystine

Info

Publication number
SE9103572D0
SE9103572D0 SE9103572A SE9103572A SE9103572D0 SE 9103572 D0 SE9103572 D0 SE 9103572D0 SE 9103572 A SE9103572 A SE 9103572A SE 9103572 A SE9103572 A SE 9103572A SE 9103572 D0 SE9103572 D0 SE 9103572D0
Authority
SE
Sweden
Prior art keywords
organic salts
diacetyl cystine
cystine
diacetyl
processes
Prior art date
Application number
SE9103572A
Other languages
English (en)
Swedish (sv)
Inventor
Carl-Magnus Andersson
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9103572A priority Critical patent/SE9103572D0/xx
Publication of SE9103572D0 publication Critical patent/SE9103572D0/xx
Priority to NZ245077A priority patent/NZ245077A/en
Priority to ZA928739A priority patent/ZA928739B/xx
Priority to IL10377892A priority patent/IL103778A/xx
Priority to YU99092A priority patent/YU48594B/sh
Priority to APAP/P/1992/000448A priority patent/AP350A/en
Priority to HR9103572-5A priority patent/HRP921322B1/xx
Priority to TNTNSN92108A priority patent/TNSN92108A1/fr
Priority to MA23006A priority patent/MA22716A1/fr
Priority to IS3949A priority patent/IS1645B/is
Priority to KR1019940701815A priority patent/KR100256185B1/ko
Priority to DK92924975.3T priority patent/DK0621862T3/da
Priority to SK632-94A priority patent/SK281697B6/sk
Priority to MYPI92002155A priority patent/MY110523A/en
Priority to JP51003993A priority patent/JP3302018B2/ja
Priority to DE69213256T priority patent/DE69213256T2/de
Priority to ES92924975T priority patent/ES2090713T3/es
Priority to PL92303924A priority patent/PL170787B1/pl
Priority to PCT/SE1992/000807 priority patent/WO1993011104A1/en
Priority to SG1996004497A priority patent/SG73962A1/en
Priority to CZ941297A priority patent/CZ282085B6/cs
Priority to US07/981,373 priority patent/US5385904A/en
Priority to AT92924975T priority patent/ATE141913T1/de
Priority to HU9401473A priority patent/HU215390B/hu
Priority to PL92314567A priority patent/PL171336B1/pl
Priority to AU30996/92A priority patent/AU657827B2/en
Priority to RU94027569/04A priority patent/RU2135468C1/ru
Priority to DZ920148A priority patent/DZ1637A1/fr
Priority to CA002123516A priority patent/CA2123516A1/en
Priority to EP92924975A priority patent/EP0621862B1/en
Priority to MX9206851A priority patent/MX9206851A/es
Priority to CN92113666A priority patent/CN1039586C/zh
Priority to SI19929200351A priority patent/SI9200351A/sl
Priority to NO941968A priority patent/NO301325B1/no
Priority to FI942504A priority patent/FI942504A0/fi
Priority to US08/335,941 priority patent/US5693858A/en
Priority to EE9400378A priority patent/EE03025B1/et
Priority to US08/484,143 priority patent/US5824681A/en
Priority to US08/476,218 priority patent/US5650538A/en
Priority to US08/477,387 priority patent/US5804582A/en
Priority to GR960402920T priority patent/GR3021546T3/el
Priority to HK62297A priority patent/HK62297A/xx
Priority to LVP-97-158A priority patent/LV11949B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • C07C319/24—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SE9103572A 1991-11-29 1991-11-29 Organic salts of n,n'-diacetyl cystine SE9103572D0 (sv)

Priority Applications (43)

Application Number Priority Date Filing Date Title
SE9103572A SE9103572D0 (sv) 1991-11-29 1991-11-29 Organic salts of n,n'-diacetyl cystine
NZ245077A NZ245077A (en) 1991-11-29 1992-11-10 Isomeric forms of n,n'-diacetyl cystine salt with an organic base, preparation and pharmaceutical compositions thereof
ZA928739A ZA928739B (en) 1991-11-29 1992-11-12 Organic salts of N,N'-diacetyl cystine.
IL10377892A IL103778A (en) 1991-11-29 1992-11-17 Organic salts of N,N'-diacetyl cystine process for their preparation and pharmaceutical compositions containing them
YU99092A YU48594B (sh) 1991-11-29 1992-11-18 Organske soli n-n'-diacetilcistina i postupak njihovog dobijanja
APAP/P/1992/000448A AP350A (en) 1991-11-29 1992-11-20 Organic salts of N,N-Diacetyl cystine.
HR9103572-5A HRP921322B1 (en) 1991-11-29 1992-11-23 Organic salts of n,n'-diacetyl cystine
TNTNSN92108A TNSN92108A1 (fr) 1991-11-29 1992-11-23 Sels organiques de n, n' -diacetyl cystine
MA23006A MA22716A1 (fr) 1991-11-29 1992-11-24 Sels organiques de n,n'-diacetyl cystine
IS3949A IS1645B (is) 1991-11-29 1992-11-24 Hliðstæð aðferð við að framleiða salt af lýsini og N,N'-tvíasetýlsystíni
EP92924975A EP0621862B1 (en) 1991-11-29 1992-11-25 Organic salts of n, n'-diacetyl cystine
CZ941297A CZ282085B6 (cs) 1991-11-29 1992-11-25 Organické soli N,N'-diacetylcystinu
DZ920148A DZ1637A1 (fr) 1991-11-29 1992-11-25 Sels organiques de n'n'-diacétyl cystine.
SK632-94A SK281697B6 (sk) 1991-11-29 1992-11-25 Soľ organickej bázy a n,n'-diacetylcystínu, spôsob jej výroby, jej použitie a farmaceutický prostriedok s jej obsahom
MYPI92002155A MY110523A (en) 1991-11-29 1992-11-25 Organic salts of n, n''-dicetyl cystine
JP51003993A JP3302018B2 (ja) 1991-11-29 1992-11-25 Ｎ，ｎ’−ジアセチルシスチンの有機塩
DE69213256T DE69213256T2 (de) 1991-11-29 1992-11-25 Organische salze von n, n'-diacetylcystin
ES92924975T ES2090713T3 (es) 1991-11-29 1992-11-25 Sales organicas de n,n'-diacetil-cistina.
PL92303924A PL170787B1 (en) 1991-11-29 1992-11-25 Method of obtaining an organic salt and n,n'-diacetlocystine
PCT/SE1992/000807 WO1993011104A1 (en) 1991-11-29 1992-11-25 Organic salts of n, n'-diacetyl cystine
SG1996004497A SG73962A1 (en) 1991-11-29 1992-11-25 Organic salts of n, n'-diacetyl cystine
KR1019940701815A KR100256185B1 (ko) 1991-11-29 1992-11-25 N,n'-디아세틸 시스틴의 유기염
US07/981,373 US5385904A (en) 1991-11-29 1992-11-25 Organic salts of N,N'-diacetyl cystine
AT92924975T ATE141913T1 (de) 1991-11-29 1992-11-25 Organische salze von n, n'-diacetylcystin
HU9401473A HU215390B (hu) 1991-11-29 1992-11-25 Eljárás N,N'-diacetil-cisztin szerves bázisokkal képzett sói és az ezeket tartalmazó gyógyászati készítmények előállítására
PL92314567A PL171336B1 (en) 1991-11-29 1992-11-25 Method of obtaining an organic salt and n,n'-diacetylocystine
AU30996/92A AU657827B2 (en) 1991-11-29 1992-11-25 Organic salts of N, N'-diacetyl cystine
RU94027569/04A RU2135468C1 (ru) 1991-11-29 1992-11-25 Органические соли n,n'-диацетилцистина, способы их получения, фармацевтическая композиция, способ лечения
DK92924975.3T DK0621862T3 (da) 1991-11-29 1992-11-25 Organiske salte af N,N-diacetylcystin
CA002123516A CA2123516A1 (en) 1991-11-29 1992-11-25 Organic salts of n,n'-diacetyl cystine
MX9206851A MX9206851A (es) 1991-11-29 1992-11-27 Sales organicas de n,n'-diacetil cistina, proceso para su preparacion y composicion farmaceutica que las contiene.
CN92113666A CN1039586C (zh) 1991-11-29 1992-11-28 制备n,n′－二乙酰胱氨酸的有机盐的方法
SI19929200351A SI9200351A (en) 1991-11-29 1992-11-30 Organic salts of n,n'-diacetyl cystine
NO941968A NO301325B1 (no) 1991-11-29 1994-05-26 Organiske salter av N,N'-diacetylcystin, farmasöytisk preparat samt anvendelse av saltene
FI942504A FI942504A0 (fi) 1991-11-29 1994-05-27 N,N'-diasetyylikystiinin orgaanisia suoloja
US08/335,941 US5693858A (en) 1991-11-29 1994-11-08 Organic salts of N,N'-diacetyl cystine
EE9400378A EE03025B1 (et) 1991-11-29 1994-11-17 Immunomoduleeriva toimega N,N'-diatsetüültsüstiini orgaanilised soolad, nende valmistamine ja kasutamine
US08/484,143 US5824681A (en) 1991-11-29 1995-06-07 Organic salts of N,N'-diacetyl cystine
US08/477,387 US5804582A (en) 1991-11-29 1995-06-07 Method for the treatment of diseases due to defects the immune system
US08/476,218 US5650538A (en) 1991-11-29 1995-06-07 Organic salts of N,N'-diacetyl cystine
GR960402920T GR3021546T3 (en) 1991-11-29 1996-11-06 Organic salts of n, n'-diacetyl cystine.
HK62297A HK62297A (en) 1991-11-29 1997-05-08 Organic salts of N,N'-diacetyl cystine
LVP-97-158A LV11949B (en) 1991-11-29 1997-08-28 N, N'-DIACETYL-CISTIN ORGANIC SALTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9103572A SE9103572D0 (sv) 1991-11-29 1991-11-29 Organic salts of n,n'-diacetyl cystine

Publications (1)

Publication Number Publication Date
SE9103572D0 true SE9103572D0 (sv) 1991-11-29

Family

ID=20384494

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9103572A SE9103572D0 (sv) 1991-11-29 1991-11-29 Organic salts of n,n'-diacetyl cystine

Country Status (38)

Country Link
US (5) US5385904A (et)
EP (1) EP0621862B1 (et)
JP (1) JP3302018B2 (et)
KR (1) KR100256185B1 (et)
CN (1) CN1039586C (et)
AP (1) AP350A (et)
AT (1) ATE141913T1 (et)
AU (1) AU657827B2 (et)
CA (1) CA2123516A1 (et)
CZ (1) CZ282085B6 (et)
DE (1) DE69213256T2 (et)
DK (1) DK0621862T3 (et)
DZ (1) DZ1637A1 (et)
EE (1) EE03025B1 (et)
ES (1) ES2090713T3 (et)
FI (1) FI942504A0 (et)
GR (1) GR3021546T3 (et)
HK (1) HK62297A (et)
HR (1) HRP921322B1 (et)
HU (1) HU215390B (et)
IL (1) IL103778A (et)
IS (1) IS1645B (et)
LV (1) LV11949B (et)
MA (1) MA22716A1 (et)
MX (1) MX9206851A (et)
MY (1) MY110523A (et)
NO (1) NO301325B1 (et)
NZ (1) NZ245077A (et)
PL (2) PL171336B1 (et)
RU (1) RU2135468C1 (et)
SE (1) SE9103572D0 (et)
SG (1) SG73962A1 (et)
SI (1) SI9200351A (et)
SK (1) SK281697B6 (et)
TN (1) TNSN92108A1 (et)
WO (1) WO1993011104A1 (et)
YU (1) YU48594B (et)
ZA (1) ZA928739B (et)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3865463A (en) * 1973-11-12 1975-02-11 Busch & Co Inc Ag Electrical adapter plug
ES2092539T3 (es) * 1991-01-10 1996-12-01 Transcend Therapeutics Inc Uso de derivados de la tiazolidina-4-carboxilato para el tratamiento de enfermedades pulmonares.
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
SE9500897D0 (sv) * 1995-03-14 1995-03-14 Astra Ab The pharmacological use of certain cystine derivatives
SE9602262D0 (sv) * 1996-06-06 1996-06-06 Astra Ab New use of derivatives of cystine
AR007398A1 (es) * 1996-06-18 1999-10-27 Astrazeneca Ab Proceso para preparar sales inorganicas de n-n'-diacetilcistina
SE9602416D0 (sv) * 1996-06-18 1996-06-18 Astra Ab New forms of an organic salt of N'N-diacetylcystine
US6017959A (en) * 1996-06-18 2000-01-25 Astra Aktiebolag Forms of organic salts of N,N'-diacetylcystine
CN1059907C (zh) * 1997-05-23 2000-12-27 中国石油化工集团公司巴陵石化岳阳石油化工总厂 一种含共轭二烯轻聚合物的选择氢化方法
US20030203006A1 (en) * 1997-10-29 2003-10-30 Ajinomoto Co. Inc. Immunomodulator
US6197749B1 (en) * 1997-10-29 2001-03-06 Ajinomoto Co., Inc. Method of suppressing immune responses by reducing intracellular content of glutathione in macrophages and monocytes
SE9800932D0 (sv) * 1998-03-20 1998-03-20 Astra Ab New compunds
EP1004302A3 (en) * 1998-10-29 2003-06-04 Ajinomoto Co., Inc. Immunomodulator
SE9900438D0 (sv) * 1999-02-10 1999-02-10 Astra Ab The pharmacological use of certian cystine derivatives
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
SE518784C2 (sv) * 2000-12-27 2002-11-19 Nactilus Ab "N-Acetyl-L-cystein med kompositioner för behandling av neoplasier"
WO2002072040A1 (fr) * 2001-03-13 2002-09-19 Ajinomoto Co., Inc. Produits cosmetiques ou preparations a usage externe pour la peau
DE60318938T2 (de) 2002-03-20 2009-01-22 Mannkind Corp., Valencia Inhalationsgerät
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
JP4990142B2 (ja) 2004-08-23 2012-08-01 マンカインド コーポレイション 薬物送達のためのジケトピペラジン塩、ジケトモルホリン塩、又はジケトジオキサン塩
HUE028691T2 (en) 2005-09-14 2016-12-28 Mannkind Corp A method for formulating a drug based on increasing the affinity of crystalline microparticle surfaces towards active ingredients
AU2007216966C1 (en) 2006-02-22 2014-03-20 Mannkind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US8438729B2 (en) * 2006-03-09 2013-05-14 Canon Kabushiki Kaisha Method of producing liquid discharge head
ES2655921T3 (es) 2008-06-13 2018-02-22 Mannkind Corporation Un inhalador de polvo seco y sistema para administración de fármacos
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2904623T3 (es) 2008-06-20 2022-04-05 Mannkind Corp Aparato interactivo para establecer un perfil en tiempo real de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010144789A2 (en) 2009-06-12 2010-12-16 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
KR20130117755A (ko) 2010-06-21 2013-10-28 맨카인드 코포레이션 건조 분말 약물 운반 시스템 및 방법
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CN102491926B (zh) * 2011-12-15 2013-09-25 青岛市药品检验所 一种硫普罗宁二硫化物的制备和纯化方法
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送系统和方法
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
JP6523247B2 (ja) 2013-03-15 2019-05-29 マンカインド コーポレイション 微結晶性ジケトピペラジン粒子の製造方法および乾燥粉末組成物の製造方法
EP3021834A1 (en) 2013-07-18 2016-05-25 MannKind Corporation Heat-stable dry powder pharmaceutical compositions and methods
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2021219376A1 (en) * 2020-04-28 2021-11-04 Unilever Ip Holdings B.V. Personal care compositions with enhanced solubility actives
WO2022067248A1 (en) * 2020-09-28 2022-03-31 Georgia Tech Research Corporation Use of cystine and derivatives thereof as anti-thrombotic and thrombolytic agents

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB592631A (en) * 1945-04-04 1947-09-24 Du Pont Cysteine and cystine
GB954268A (en) 1962-02-26 1964-04-02 Mead Johnson & Co Decongestant compositions comprising n-acylated sulphydryl compounds
FR8205M (et) * 1968-12-20 1970-09-14
US3647834A (en) 1969-08-11 1972-03-07 Mead Johnson & Co Zinc mercaptide n-acetylcysteine carboxylate salts
US3878305A (en) 1972-05-25 1975-04-15 Procter & Gamble Fortification of foodstuffs with n-acyl derivatives of sulphur-containing l-amino acids
US3952115A (en) * 1975-04-02 1976-04-20 The Procter & Gamble Company Fortification of foodstuffs with N-acyl derivatives of sulfur-containing L-amino acid esters
US4141734A (en) * 1975-09-11 1979-02-27 Ciba-Geiby Ag Photographic developing process
US4093739A (en) * 1977-06-15 1978-06-06 Mead Johnson & Company Mercaptoacylamidobenzoyl glycine and mucolytic process
JPS6011888B2 (ja) * 1978-10-11 1985-03-28 参天製薬株式会社 リウマチ疾患治療薬
JPS56155298A (en) 1980-05-02 1981-12-01 Tanabe Seiyaku Co Shampoo composition
GB2097256B (en) * 1981-04-02 1985-05-30 Morelle Jean V Compositions containing n-butyryl alphaaminoacids
FR2503151A1 (fr) * 1981-04-02 1982-10-08 Morelle Jean Butyryminoacides soufres. mode de preparation. emploi comme element keratogenique chez l'homme et l'animal et comme agent de fertilisation chez les vegetaux
JPS58164566A (ja) * 1982-03-09 1983-09-29 Kenji Okawa シスチン類の製造法
US4827016A (en) * 1985-09-16 1989-05-02 Morgan Lee R Method and compounds for reducing dermal inflammations
US4708965A (en) 1985-09-16 1987-11-24 Morgan Lee R Method of treating herpes virus infections with N,N'-diacetylcystine and derivatives
US4724239A (en) * 1985-09-16 1988-02-09 Morgan Lee R Method of treating chemical ulcers with N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine
JPH0660157B2 (ja) * 1985-11-20 1994-08-10 三井東圧化学株式会社 システインからシスチンを製造する方法
JPS62195356A (ja) * 1986-02-20 1987-08-28 Seiwa Kasei:Kk シスチン誘導体及びその塩
AT402931B (de) * 1986-11-07 1997-09-25 Pharmacia Gmbh Verfahren zur herstellung von neuen cystinverbindungen und derenverwendung
SE8704542D0 (sv) * 1987-11-19 1987-11-19 Draco Ab New derivatives of cysteine
IL98310A (en) * 1990-06-08 1996-08-04 Astra Ab Medicinal preparations containing a history of cystine
TW221376B (et) * 1990-06-28 1994-03-01 Astra Ab
GB9111885D0 (en) * 1991-06-03 1991-07-24 Erba Carlo Spa Nerve growth factor for use in the prevention and treatment of viral infections

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US5804582A (en) 1998-09-08
DZ1637A1 (fr) 2002-02-17
US5385904A (en) 1995-01-31
EP0621862A1 (en) 1994-11-02
JPH07501539A (ja) 1995-02-16
NO301325B1 (no) 1997-10-13
AP9200448A0 (en) 1993-01-31
US5824681A (en) 1998-10-20
DE69213256T2 (de) 1997-01-23
WO1993011104A1 (en) 1993-06-10
HRP921322A2 (en) 1996-10-31
EP0621862B1 (en) 1996-08-28
IS1645B (is) 1997-03-25
HUT70851A (en) 1995-11-28
SK281697B6 (sk) 2001-06-11
AP350A (en) 1994-08-09
SG73962A1 (en) 2000-07-18
ZA928739B (en) 1993-06-09
LV11949A (lv) 1998-01-20
TNSN92108A1 (fr) 1993-06-08
NO941968L (no) 1994-05-26
CN1073683A (zh) 1993-06-30
PL170787B1 (en) 1997-01-31
MX9206851A (es) 1993-05-01
PL171336B1 (en) 1997-04-30
JP3302018B2 (ja) 2002-07-15
IS3949A (is) 1993-05-30
YU99092A (sh) 1995-12-04
HK62297A (en) 1997-05-16
GR3021546T3 (en) 1997-02-28
RU2135468C1 (ru) 1999-08-27
DK0621862T3 (da) 1996-09-16
YU48594B (sh) 1998-12-23
NZ245077A (en) 1995-04-27
CZ282085B6 (cs) 1997-05-14
CA2123516A1 (en) 1993-06-10
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ATE141913T1 (de) 1996-09-15
NO941968D0 (no) 1994-05-26
IL103778A (en) 1997-08-14
FI942504A (fi) 1994-05-27
FI942504A0 (fi) 1994-05-27
CN1039586C (zh) 1998-08-26
EE03025B1 (et) 1997-08-15
SK63294A3 (en) 1995-02-08
IL103778A0 (en) 1993-04-04
CZ129794A3 (en) 1995-01-18
US5693858A (en) 1997-12-02
KR100256185B1 (ko) 2000-05-15
US5650538A (en) 1997-07-22
AU657827B2 (en) 1995-03-23
MA22716A1 (fr) 1993-07-01
HRP921322B1 (en) 1998-12-31
ES2090713T3 (es) 1996-10-16
LV11949B (en) 1998-07-20
HU215390B (hu) 1998-12-28
DE69213256D1 (de) 1996-10-02

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