SE9100342D0 - Novel steroid esters - Google Patents

Novel steroid esters

Info

Publication number
SE9100342D0
SE9100342D0 SE9100342A SE9100342A SE9100342D0 SE 9100342 D0 SE9100342 D0 SE 9100342D0 SE 9100342 A SE9100342 A SE 9100342A SE 9100342 A SE9100342 A SE 9100342A SE 9100342 D0 SE9100342 D0 SE 9100342D0
Authority
SE
Sweden
Prior art keywords
hydrogen
pct
straight
hydrocarbon chain
branched hydrocarbon
Prior art date
Application number
SE9100342A
Other languages
English (en)
Swedish (sv)
Inventor
B Axelsson
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9100342A priority Critical patent/SE9100342D0/xx
Publication of SE9100342D0 publication Critical patent/SE9100342D0/xx
Priority to IL10054291A priority patent/IL100542A/xx
Priority to TW080110262A priority patent/TW287166B/zh
Priority to NZ241211A priority patent/NZ241211A/xx
Priority to ZA92234A priority patent/ZA92234B/xx
Priority to IE016792A priority patent/IE920167A1/en
Priority to DZ920006A priority patent/DZ1554A1/fr
Priority to YU6492A priority patent/YU48893B/sh
Priority to SI9210064A priority patent/SI9210064B/sl
Priority to APAP/P/1992/000354A priority patent/AP365A/en
Priority to DE69224982T priority patent/DE69224982T2/de
Priority to MX9200374A priority patent/MX9200374A/es
Priority to RO93-01094A priority patent/RO111272B1/ro
Priority to JP4504217A priority patent/JP2947933B2/ja
Priority to PCT/SE1992/000056 priority patent/WO1992013873A1/en
Priority to US08/094,100 priority patent/US5614514A/en
Priority to HU9302243A priority patent/HU221168B1/hu
Priority to CA002100453A priority patent/CA2100453A1/en
Priority to SK797-93A priority patent/SK281802B6/sk
Priority to KR1019930702299A priority patent/KR100205835B1/ko
Priority to AT92904423T priority patent/ATE164589T1/de
Priority to PL92300351A priority patent/PL170383B1/pl
Priority to EP92904423A priority patent/EP0572451B1/en
Priority to RU93053632A priority patent/RU2112775C1/ru
Priority to AU12358/92A priority patent/AU661472C/en
Priority to ES92904423T priority patent/ES2114931T3/es
Priority to UA93004296A priority patent/UA43825C2/uk
Priority to DK92904423T priority patent/DK0572451T3/da
Priority to CS931495A priority patent/CZ282057B6/cs
Priority to MYPI92000158A priority patent/MY111502A/en
Priority to IS3809A priority patent/IS1653B/is
Priority to CN92100797A priority patent/CN1039329C/zh
Priority to PT100087A priority patent/PT100087B/pt
Priority to MA22693A priority patent/MA22407A1/fr
Priority to TNTNSN92008A priority patent/TNSN92008A1/fr
Priority to NO932762A priority patent/NO304074B1/no
Priority to BG98011A priority patent/BG61816B1/bg
Priority to FI933451A priority patent/FI933451A/fi
Priority to EE9400330A priority patent/EE03110B1/xx
Priority to US08/493,733 priority patent/US5888995A/en
Priority to CN96122759A priority patent/CN1076607C/zh
Priority to CN96114411A priority patent/CN1076606C/zh
Priority to HK98103446A priority patent/HK1004335A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SE9100342A 1991-02-04 1991-02-04 Novel steroid esters SE9100342D0 (sv)

Priority Applications (43)

Application Number Priority Date Filing Date Title
SE9100342A SE9100342D0 (sv) 1991-02-04 1991-02-04 Novel steroid esters
IL10054291A IL100542A (en) 1991-02-04 1991-12-27 Esters of 16, 17-alkylidene-dioxy-6-and/or 9-fluoro-11,21-dihydroxy-pregna-4-ene (and-1-4-diene)-3,20-diones
TW080110262A TW287166B (fi) 1991-02-04 1991-12-30
NZ241211A NZ241211A (en) 1991-02-04 1992-01-06 16alpha,17alpha-alkylidenedioxy-11b,21-dihydroxypregan -4-ene-3,20-dione derivatives substituted by halogen in either or both of the 6alpha- or the 9alpha- position; pharmaceutical compositions, methods of preparation and treatment
ZA92234A ZA92234B (en) 1991-02-04 1992-01-13 Novel steroid esters
IE016792A IE920167A1 (en) 1991-02-04 1992-01-21 Novel steroid esters, their preparation and pharmaceutical¹use
DZ920006A DZ1554A1 (fr) 1991-02-04 1992-01-22 Steroïdes-esters nouveaux.
YU6492A YU48893B (sh) 1991-02-04 1992-01-22 Novi steroidni estri
SI9210064A SI9210064B (sl) 1991-02-04 1992-01-22 Nove antiinflamatorno in antialergijsko aktivne spojine, glukokortikosteroidi ter postopki za njihovo pripravo
APAP/P/1992/000354A AP365A (en) 1991-02-04 1992-01-27 Novel steroid esters.
CS931495A CZ282057B6 (cs) 1991-02-04 1992-01-29 Nové steroid-estery
AT92904423T ATE164589T1 (de) 1991-02-04 1992-01-29 Neue steroid-ester
DK92904423T DK0572451T3 (da) 1991-02-04 1992-01-29 Ukendte steroidistere
RO93-01094A RO111272B1 (ro) 1991-02-04 1992-01-29 Derivati de glucocorticosteroizi, procedeu pentru prepararea acestora si compozitie farmaceutica,pe baza de acesti compusi
JP4504217A JP2947933B2 (ja) 1991-02-04 1992-01-29 新規ステロイドエステル
PCT/SE1992/000056 WO1992013873A1 (en) 1991-02-04 1992-01-29 Novel steroid esters
US08/094,100 US5614514A (en) 1991-02-04 1992-01-29 Steroid esters
HU9302243A HU221168B1 (en) 1991-02-04 1992-01-29 Method for producing new 11-hydroxy-prega-4-ene-3,20-dione-21-esters and pharmaceutical compositions of the same
CA002100453A CA2100453A1 (en) 1991-02-04 1992-01-29 Novel steroid esters
SK797-93A SK281802B6 (sk) 1991-02-04 1992-01-29 Steroidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie
KR1019930702299A KR100205835B1 (ko) 1991-02-04 1992-01-29 신규 스테로이드 에스테르
DE69224982T DE69224982T2 (de) 1991-02-04 1992-01-29 Neue steroid-ester
PL92300351A PL170383B1 (pl) 1991-02-04 1992-01-29 Sposób wytwarzania nowych estrów pregnenu PL PL PL PL PL PL PL PL
EP92904423A EP0572451B1 (en) 1991-02-04 1992-01-29 Novel steroid esters
RU93053632A RU2112775C1 (ru) 1991-02-04 1992-01-29 Стероидные эфиры или их стереоизомеры, способ их получения, фармацевтическая композиция
AU12358/92A AU661472C (en) 1991-02-04 1992-01-29 Novel steroid esters
ES92904423T ES2114931T3 (es) 1991-02-04 1992-01-29 Nuevos esteres esteroidales.
UA93004296A UA43825C2 (uk) 1991-02-04 1992-01-29 Стероїдні ефіри або їх стереоізомери, спосіб їх одержання, фармацевтична композиція на їх основі
MX9200374A MX9200374A (es) 1991-02-04 1992-01-29 Nuevos esteres esteroides, procedimiento para su preparacion y preparacion farmaceutica que los contiene.
MYPI92000158A MY111502A (en) 1991-02-04 1992-01-31 Novel steroid esters
IS3809A IS1653B (is) 1991-02-04 1992-02-03 Hliðstæð aðferð við framleiðslu nýrra sykursteraestera
CN92100797A CN1039329C (zh) 1991-02-04 1992-02-03 制备甾酯类化合物的方法
PT100087A PT100087B (pt) 1991-02-04 1992-02-03 Novos esteres de esteroides
MA22693A MA22407A1 (fr) 1991-02-04 1992-02-03 Steroides-esters nouveaux
TNTNSN92008A TNSN92008A1 (fr) 1991-02-04 1992-02-04 Steroides-esters nouveaux
BG98011A BG61816B1 (bg) 1991-02-04 1993-08-02 Нови стероидни естери
NO932762A NO304074B1 (no) 1991-02-04 1993-08-02 Nye steroidestere, farmasöytisk preparat inneholdende disse forbindelsene og deres anvendelse
FI933451A FI933451A (fi) 1991-02-04 1993-08-03 Nya steroidestrar
EE9400330A EE03110B1 (et) 1991-02-04 1994-11-23 Steroidi estrid, nende valmistamise protsess ja neid sisaldavad ravimpreparaadid
US08/493,733 US5888995A (en) 1991-02-04 1995-06-22 Steroid esters
CN96122759A CN1076607C (zh) 1991-02-04 1996-10-22 制备含有新的甾酯类化合物的药物组合物的方法
CN96114411A CN1076606C (zh) 1991-02-04 1996-11-01 新的甾类在制备具有抗炎和抗过敏活性的药物中的应用
HK98103446A HK1004335A1 (en) 1991-02-04 1998-04-24 Novel steroid esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9100342A SE9100342D0 (sv) 1991-02-04 1991-02-04 Novel steroid esters

Publications (1)

Publication Number Publication Date
SE9100342D0 true SE9100342D0 (sv) 1991-02-04

Family

ID=20381807

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9100342A SE9100342D0 (sv) 1991-02-04 1991-02-04 Novel steroid esters

Country Status (38)

Country Link
US (1) US5614514A (fi)
EP (1) EP0572451B1 (fi)
JP (1) JP2947933B2 (fi)
KR (1) KR100205835B1 (fi)
CN (3) CN1039329C (fi)
AP (1) AP365A (fi)
AT (1) ATE164589T1 (fi)
BG (1) BG61816B1 (fi)
CA (1) CA2100453A1 (fi)
CZ (1) CZ282057B6 (fi)
DE (1) DE69224982T2 (fi)
DK (1) DK0572451T3 (fi)
DZ (1) DZ1554A1 (fi)
EE (1) EE03110B1 (fi)
ES (1) ES2114931T3 (fi)
FI (1) FI933451A (fi)
HK (1) HK1004335A1 (fi)
HU (1) HU221168B1 (fi)
IE (1) IE920167A1 (fi)
IL (1) IL100542A (fi)
IS (1) IS1653B (fi)
MA (1) MA22407A1 (fi)
MX (1) MX9200374A (fi)
MY (1) MY111502A (fi)
NO (1) NO304074B1 (fi)
NZ (1) NZ241211A (fi)
PL (1) PL170383B1 (fi)
PT (1) PT100087B (fi)
RO (1) RO111272B1 (fi)
RU (1) RU2112775C1 (fi)
SE (1) SE9100342D0 (fi)
SK (1) SK281802B6 (fi)
TN (1) TNSN92008A1 (fi)
TW (1) TW287166B (fi)
UA (1) UA43825C2 (fi)
WO (1) WO1992013873A1 (fi)
YU (1) YU48893B (fi)
ZA (1) ZA92234B (fi)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
WO1994015947A1 (en) * 1993-01-08 1994-07-21 Astra Aktiebolag Novel colon- or ileum-specific steroid derivatives
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
AU775500B2 (en) 1999-05-27 2004-08-05 Euro-Celtique S.A. Preparations for the application of anti-infective and/or anti-inflammatory agents
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
WO2003070745A2 (en) 2002-02-20 2003-08-28 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids
US20050009798A1 (en) 2002-02-20 2005-01-13 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
RU2330858C2 (ru) 2002-07-08 2008-08-10 Глаксомитклайн Истраживацки Центар Загреб Д.О.О. Новые соединения, составы и способы лечения воспалительных заболеваний и состояний
RS20050006A (en) 2002-07-08 2007-09-21 Glaxo Smith Kline Istraživački Centar Zagreb D.O.O., Novel compounds,compositions as carriers for steroid/non- steroid anti-inflammatory,antineoplastic and antiviral active molecules
AU2003265576A1 (en) * 2002-08-23 2004-03-11 The Mclean Hospital Corporation Corticosteroid conjugates and uses thereof
WO2004033478A2 (en) * 2002-10-08 2004-04-22 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
WO2005016352A1 (en) * 2003-08-05 2005-02-24 Sepracor Inc. AMINO ACID AND PEPTIDE-MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH ß2 ADRENERGIC AGONISTS
MX2007005073A (es) 2004-10-27 2007-06-25 Glaxosmithkline Zagreb Conjugados con actividad antiinflamtoria.
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US8737506B1 (en) 2010-12-29 2014-05-27 Sprint Communications Company L.P. Determination of transmit diversity transmission delays
US8437713B1 (en) 2011-02-16 2013-05-07 Sprint Communications Company L.P. Wireless transmit diversity control by location of a wireless communication device
US8565686B2 (en) 2011-06-30 2013-10-22 Sprint Communications Company L.P. Power status multipath search window sizing for wireless communications
DK2797601T3 (en) 2012-02-10 2018-06-14 Taiwan Liposome Co Ltd PHARMACEUTICAL COMPOSITIONS FOR REDUCING COMPLICATIONS BY Ocular steroid
JP5965187B2 (ja) * 2012-03-30 2016-08-03 小林製薬株式会社 油性軟膏剤
CN109985048B (zh) * 2017-12-29 2021-06-29 广州市赛普特医药科技股份有限公司 2β,3α,5α-三羟基雄甾-6-酮用于炎症反应的治疗

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US3126375A (en) * 1964-03-24 Chioacyl
US3197469A (en) * 1958-08-06 1965-07-27 Pharmaceutical Res Products In 16, 17-acetals and ketals of 6-halo-16, 17-dihydroxy steroids of the pregnane seriesand intermediates therefor
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378109B (fi) * 1972-05-19 1975-08-18 Bofors Ab
US3796701A (en) * 1973-02-26 1974-03-12 Squibb & Sons Inc 5alpha,9-oxazino steroids and 9-carboxamido steroids
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4304727A (en) * 1980-12-05 1981-12-08 The Upjohn Company 9α-Debromination
JPS58176485A (ja) * 1982-04-08 1983-10-15 Nippon Denso Co Ltd 可変容量圧縮機
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
JPS6067496A (ja) * 1983-09-26 1985-04-17 Ota Seiyaku Kk フルオシノロン１６，１７−アセトニド２１−ブチレ−トおよびその製造法
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters

Also Published As

Publication number Publication date
UA43825C2 (uk) 2002-01-15
KR100205835B1 (ko) 1999-07-01
NO932762D0 (no) 1993-08-02
AU661472B2 (en) 1995-07-27
SK281802B6 (sk) 2001-08-06
CN1039329C (zh) 1998-07-29
FI933451A0 (fi) 1993-08-03
ATE164589T1 (de) 1998-04-15
NO932762L (no) 1993-08-02
CN1064078A (zh) 1992-09-02
JP2947933B2 (ja) 1999-09-13
IL100542A0 (en) 1992-09-06
CZ149593A3 (en) 1994-03-16
MY111502A (en) 2000-07-31
RO111272B1 (ro) 1996-08-30
JPH06505233A (ja) 1994-06-16
HU9302243D0 (en) 1993-10-28
CN1076607C (zh) 2001-12-26
EP0572451A1 (en) 1993-12-08
AU1235892A (en) 1992-09-07
NZ241211A (en) 1993-08-26
CN1158726A (zh) 1997-09-10
MA22407A1 (fr) 1992-10-01
YU6492A (sh) 1994-12-28
US5614514A (en) 1997-03-25
PT100087B (pt) 1999-09-30
HUT64972A (en) 1994-03-28
HK1004335A1 (en) 1998-11-20
DZ1554A1 (fr) 2002-02-17
BG98011A (bg) 1994-04-29
SK79793A3 (en) 1994-03-09
IE920167A1 (en) 1992-08-12
PT100087A (pt) 1993-05-31
WO1992013873A1 (en) 1992-08-20
DK0572451T3 (da) 1998-10-19
PL170383B1 (pl) 1996-12-31
TW287166B (fi) 1996-10-01
IS1653B (is) 1997-06-20
CZ282057B6 (cs) 1997-05-14
DE69224982T2 (de) 1998-07-30
IS3809A (is) 1992-08-05
FI933451A (fi) 1993-08-03
EP0572451B1 (en) 1998-04-01
ZA92234B (en) 1992-10-28
CN1076606C (zh) 2001-12-26
ES2114931T3 (es) 1998-06-16
IL100542A (en) 1997-02-18
AP365A (en) 1994-10-21
CA2100453A1 (en) 1992-08-05
CN1155418A (zh) 1997-07-30
AP9200354A0 (en) 1992-01-31
NO304074B1 (no) 1998-10-19
YU48893B (sh) 2002-10-18
TNSN92008A1 (fr) 1993-06-08
MX9200374A (es) 1992-08-01
HU221168B1 (en) 2002-08-28
EE03110B1 (et) 1998-08-17
DE69224982D1 (de) 1998-05-07
RU2112775C1 (ru) 1998-06-10
BG61816B1 (bg) 1998-06-30

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